IRF3 and type i interferons fuel a fatal response to myocardial infarction

Nature Medicine

Volumn 23, Issue 12, 2017, Pages 1481-1487

  King, Kevin R ^a,b,c,d   Aguirre, Aaron D ^a   Ye, Yu Xiang ^a,e   Sun, Yuan ^a   Roh, Jason D ^a   Ng, Richard P ^a,f   Kohler, Rainer H ^a   Arlauckas, Sean P ^a   Yoshiko, V ^a   Savo, Andrej ^a,d   Sadreyev, Ruslan I ^a   Kelly, Mark ^a   Fitzgibbons, Timothy P ^g   Fitzgerald, Katherine A ^g   Mitchison, Timothy ^d   Libby, Peter ^d   Nahrendorf, Matthias ^a   Weissleder, Ralph ^a,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^f HARVARD COLLEGE   (United States)

^g UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYCLIC GMP; CYCLIC GMP AMP SYNTHASE; CYTOKINE; INTERFERON; INTERFERON REGULATORY FACTOR 3; NEUTRALIZING ANTIBODY; RNA; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; IFNAR1 PROTEIN, MOUSE; IRF3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE FAILURE; HEART VENTRICLE REMODELING; INFLAMMATORY CELL; LEUKOCYTE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA SEQUENCE; ANIMAL; C57BL MOUSE; CELL CULTURE; GENETICS; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; MORTALITY; PATHOLOGY; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX;

ANIMALS; CELLS, CULTURED; CYTOKINES; INFLAMMATION; INTERFERON REGULATORY FACTOR-3; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; RECEPTOR, INTERFERON ALPHA-BETA; SEVERITY OF ILLNESS INDEX;

EID: 85034837637     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4428     Document Type: Article

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