NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction

Oncotarget

Volumn 8, Issue 59, 2017, Pages 99740-99756

  Pavillard, Luís E ^a   Cañadas Lozano, Diego ^a   Alcocer Gómez, Elísabet ^a   Marín Aguilar, Fabiola ^a   Pereira, Sheila ^b   Robertson, Avril A B ^c   Muntané, Jordi ^b,g   Ryffel, Bernhard ^d   Cooper, Matthew A ^c   Quiles, José L ^h   Bullón, Pedro ^a   Ruiz Cabello, Jesús ^e,f   Cordero, Mario D ^h  

^a UNIVERSITY OF SEVILLE   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d Molecular Immunology   (France)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^g INSTITUTO DE SALUD CARLOS III   (Spain)

^h UNIVERSITY OF GRANADA   (Spain)

Author keywords

Autophagy; Cardiac damage; MCC950; NLRP3 inflammasome

Indexed keywords

CRYOPYRIN; INFLAMMASOME; MCC 950; PROTEIN INHIBITOR; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; HEART INJURY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIPID DIET; MALE; METABOLIC DISORDER; MOLECULAR MECHANICS; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PROTEIN SYNTHESIS INHIBITION; SUGAR INTAKE; THP-1 CELL LINE;

EID: 85034669140     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.20763     Document Type: Article

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