Tailored Multivalent Neo-Glycoproteins: Synthesis, Evaluation, and Application of a Library of Galectin-3-Binding Glycan Ligands

Bioconjugate Chemistry

Volumn 28, Issue 11, 2017, Pages 2832-2840

  Laaf, Dominic ^a   Bojarová, Pavla ^b   Pelantová, Helena ^b   Křen, Vladimír ^b   Elling, Lothar ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b INSTITUTE OF MICROBIOLOGY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSAYS; BINDING ENERGY; BODY FLUIDS; CHELATION; DIAGNOSIS; DISEASES; ENZYMES; EPITOPES; GLYCOSYLATION; POLYSACCHARIDES; TUMORS;

BINDING LECTIN; EARLY CANCER; GALECTINS; GLYCANS; GLYCOSYLATIONS; HIGH SELECTIVITY; SYNTHESIS EVALUATION; TUMOR ANGIOGENESIS; TUMOR BIOMARKERS; TUMOR METASTASIS;

GLYCOPROTEINS;

BOVINE SERUM ALBUMIN; EPITOPE; GALECTIN 3; GLYCAN; N ACETYLGALACTOSAMINE; NEOGLYCOPROTEIN; AMINOSUGAR; GLYCOPROTEIN; LIGAND; N-ACETYLLACTOSAMINE; OLIGOSACCHARIDE; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; BIOTINYLATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCOPROTEIN SYNTHESIS; GLYCOSYLATION; HUMAN; IC50; IN VITRO STUDY; INHIBITION CONSTANT; LECTIN BINDING; MOLECULAR IMAGING; SERUM; ANIMAL; ANTAGONISTS AND INHIBITORS; BOVINE; CHEMISTRY; COMBINATORIAL CHEMISTRY; METABOLISM; SYNTHESIS;

AMINO SUGARS; ANIMALS; CATTLE; COMBINATORIAL CHEMISTRY TECHNIQUES; GALECTIN 3; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; LIGANDS; OLIGOSACCHARIDES; PROTEIN BINDING; SERUM ALBUMIN, BOVINE;

EID: 85034109121     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.7b00520     Document Type: Article

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