1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 14, 2010, Pages 5367-5378

  Salameh, Bader A ^a   Cumpstey, Ian ^b   Sundin, Anders ^b   Leffler, Hakon ^b   Nilsson, Ulf J ^b  

^a HASHEMITE UNIVERSITY   (Jordan)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Azide; Galactose; Galectin; Inhibition; Triazole

Indexed keywords

1H 1,2,3 TRIAZOL 1 YL THIODIGALACTOSIDE DERIVATIVE; ACETYLENE DERIVATIVE; AZIDE; COPPER DERIVATIVE; ECALECTIN; GALACTOSIDE; GALECTIN 3; GALECTIN 7; GALECTIN 8; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CYCLOADDITION; DRUG BINDING; DRUG CONFORMATION; DRUG SELECTIVITY; DRUG SYNTHESIS;

CATALYSIS; GALECTIN 3; HUMANS; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; THIOGALACTOSIDES; TRIAZOLES;

EID: 77955335001     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.05.040     Document Type: Article

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