Screening for galectin-3 inhibitors from synthetic lacto-N-biose libraries using microscale affinity chromatography coupled to mass spectrometry

Journal of Organic Chemistry

Volumn 71, Issue 19, 2006, Pages 7146-7154

  Fort, Sébastien ^a,b   Kim, Hyo Sun ^a   Hindsgaul, Ole ^a,c  

^a UNIVERSITY OF ALBERTA   (Canada)

^b CENTRE DE RECHERCHES SUR LES MACROMOLÉCULES VÉGÉTALES CERMAV CNRS   (France)

^c CARLSBERG LABORATORY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; BIOSYNTHESIS; HYDROPHOBIC CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; ONCOLOGY; POLYSACCHARIDES;

APOPTOSIS; DISACCHARIDE LIBRARIES; MICROSCALE AFFINITY; SYNTHETIC MODIFICATIONS;

PROTEINS;

BETA DEXTRO GALACTOPYRANOSYL(1-3) BETA DEXTRO GLUCOPYRANOSYL(LACTO N BIOSE) DERIVATIVE; DISACCHARIDE; GALECTIN 3; GLUCOPYRANOSIDE; LACTO N BIOSE DERIVATIVE; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; APOPTOSIS; ARTICLE; BINDING AFFINITY; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CHEMICAL MODIFICATION; CHEMICAL REACTION; INFLAMMATION; LECTIN BINDING; MASS SPECTROMETRY; METASTASIS; ORGANIC CHEMISTRY; STRUCTURE ANALYSIS;

ACETYLGLUCOSAMINE; CHROMATOGRAPHY, AFFINITY; DISACCHARIDES; GALECTIN 3; LIGANDS; MASS SPECTROMETRY; MOLECULAR STRUCTURE; PROTEIN BINDING;

EID: 33749000292     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060485v     Document Type: Article

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