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Volumn 40, Issue , 2018, Pages 17-27

Sleep and Alzheimer's disease: A pivotal role for the suprachiasmatic nucleus

Author keywords

Aging; Alzheimer's disease; Circadian rhythm; Dementia; Molecular clock; Sleep; Suprachiasmatic nucleus

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; GROWTH FACTOR; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; NEUROTENSIN; PROKINETICIN 2; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 85033467615     PISSN: 10870792     EISSN: 15322955     Source Type: Journal    
DOI: 10.1016/j.smrv.2017.07.005     Document Type: Review
Times cited : (76)

References (159)
  • 1
    • 84941331228 scopus 로고    scopus 로고
    • World Alzheimer report 2015. The global impact of dementia. An analysis of prevalence, incidence, cost and trends
    • Alzheimer's Disease International London
    • Prince, M., Wimo, A.G.M., Ali, G.C., Wu, Y.T., Prina, M., World Alzheimer report 2015. The global impact of dementia. An analysis of prevalence, incidence, cost and trends., 2015, Alzheimer's Disease International, London.
    • (2015)
    • Prince, M.1    Wimo, A.G.M.2    Ali, G.C.3    Wu, Y.T.4    Prina, M.5
  • 2
    • 67650844275 scopus 로고    scopus 로고
    • Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention
    • Qiu, C., Kivipelto, M., von Strauss, E., Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. Dialog Clin Neurosci 11:2 (2009), 111–128.
    • (2009) Dialog Clin Neurosci , vol.11 , Issue.2 , pp. 111-128
    • Qiu, C.1    Kivipelto, M.2    von Strauss, E.3
  • 3
    • 7944233158 scopus 로고    scopus 로고
    • Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases
    • Selkoe, D.J., Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat Cell Biol 6:11 (2004), 1054–1061.
    • (2004) Nat Cell Biol , vol.6 , Issue.11 , pp. 1054-1061
    • Selkoe, D.J.1
  • 4
    • 0031711244 scopus 로고    scopus 로고
    • Neurofibrillary tangles and Alzheimer's disease
    • Brion, J.P., Neurofibrillary tangles and Alzheimer's disease. Eur Neurol 40:3 (1998), 130–140.
    • (1998) Eur Neurol , vol.40 , Issue.3 , pp. 130-140
    • Brion, J.P.1
  • 5
    • 0025899041 scopus 로고
    • Amyloid deposition as the central event in the aetiology of Alzheimer's disease
    • Hardy, J., Allsop, D., Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 12:10 (1991), 383–388.
    • (1991) Trends Pharmacol Sci , vol.12 , Issue.10 , pp. 383-388
    • Hardy, J.1    Allsop, D.2
  • 7
    • 80051544073 scopus 로고    scopus 로고
    • Animal models in the drug discovery pipeline for Alzheimer's disease
    • Van Dam, D., De Deyn, P.P., Animal models in the drug discovery pipeline for Alzheimer's disease. Br J Pharmacol 164:4 (2011), 1285–1300.
    • (2011) Br J Pharmacol , vol.164 , Issue.4 , pp. 1285-1300
    • Van Dam, D.1    De Deyn, P.P.2
  • 8
    • 0037174346 scopus 로고    scopus 로고
    • Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study
    • Lyketsos, C.G., Lopez, O., Jones, B., Fitzpatrick, A.L., Breitner, J., DeKosky, S., Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA 288:12 (2002), 1475–1483.
    • (2002) JAMA , vol.288 , Issue.12 , pp. 1475-1483
    • Lyketsos, C.G.1    Lopez, O.2    Jones, B.3    Fitzpatrick, A.L.4    Breitner, J.5    DeKosky, S.6
  • 9
    • 84873571505 scopus 로고    scopus 로고
    • Behavioral symptoms in mild cognitive impairment as compared with Alzheimer's disease and healthy older adults
    • Van der Mussele, S., Le Bastard, N., Vermeiren, Y., Saerens, J., Somers, N., Marien, P., et al. Behavioral symptoms in mild cognitive impairment as compared with Alzheimer's disease and healthy older adults. Int J Geriatr Psychiatry 28:3 (2013), 265–275.
    • (2013) Int J Geriatr Psychiatry , vol.28 , Issue.3 , pp. 265-275
    • Van der Mussele, S.1    Le Bastard, N.2    Vermeiren, Y.3    Saerens, J.4    Somers, N.5    Marien, P.6
  • 10
    • 84912087058 scopus 로고    scopus 로고
    • Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease
    • Vermeiren, Y., Van Dam, D., Aerts, T., Engelborghs, S., De Deyn, P.P., Brain region-specific monoaminergic correlates of neuropsychiatric symptoms in Alzheimer's disease. J Alzheimer's Dis JAD 41:3 (2014), 819–833.
    • (2014) J Alzheimer's Dis JAD , vol.41 , Issue.3 , pp. 819-833
    • Vermeiren, Y.1    Van Dam, D.2    Aerts, T.3    Engelborghs, S.4    De Deyn, P.P.5
  • 11
    • 84986879605 scopus 로고    scopus 로고
    • Neuropsychiatric disturbances in Alzheimer's disease: what have we learned from neuropathological studies?
    • Van Dam, D., Vermeiren, Y., Dekker, A.D., Naude, P.J., De Deyn, P.P., Neuropsychiatric disturbances in Alzheimer's disease: what have we learned from neuropathological studies?. Curr Alzheim Res 13:10 (2016), 1145–1164.
    • (2016) Curr Alzheim Res , vol.13 , Issue.10 , pp. 1145-1164
    • Van Dam, D.1    Vermeiren, Y.2    Dekker, A.D.3    Naude, P.J.4    De Deyn, P.P.5
  • 12
    • 0030428313 scopus 로고    scopus 로고
    • Behavioral and psychological signs and symptoms of dementia: a consensus statement on current knowledge and implications for research and treatment
    • Finkel, S.I., Costa e Silva, J., Cohen, G., Miller, S., Sartorius, N., Behavioral and psychological signs and symptoms of dementia: a consensus statement on current knowledge and implications for research and treatment. Int Psychogeriatr 8:Suppl. S3 (1997), 497–500.
    • (1997) Int Psychogeriatr , vol.8 , pp. 497-500
    • Finkel, S.I.1    Costa e Silva, J.2    Cohen, G.3    Miller, S.4    Sartorius, N.5
  • 14
    • 20944443191 scopus 로고    scopus 로고
    • Sleep disturbance in mild to moderate Alzheimer's disease
    • Moran, M., Lynch, C.A., Walsh, C., Coen, R., Coakley, D., Lawlor, B.A., Sleep disturbance in mild to moderate Alzheimer's disease. Sleep Med 6:4 (2005), 347–352.
    • (2005) Sleep Med , vol.6 , Issue.4 , pp. 347-352
    • Moran, M.1    Lynch, C.A.2    Walsh, C.3    Coen, R.4    Coakley, D.5    Lawlor, B.A.6
  • 15
    • 69549118448 scopus 로고    scopus 로고
    • Sleep disturbances in older adults with mild cognitive impairment
    • Beaulieu-Bonneau, S., Hudon, C., Sleep disturbances in older adults with mild cognitive impairment. Int Psychogeriatr IPA 21:4 (2009), 654–666.
    • (2009) Int Psychogeriatr IPA , vol.21 , Issue.4 , pp. 654-666
    • Beaulieu-Bonneau, S.1    Hudon, C.2
  • 16
    • 2442502760 scopus 로고    scopus 로고
    • Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia
    • Hatfield, C.F., Herbert, J., van Someren, E.J., Hodges, J.R., Hastings, M.H., Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia. Brain J Neurol 127:Pt. 5 (2004), 1061–1074.
    • (2004) Brain J Neurol , vol.127 , pp. 1061-1074
    • Hatfield, C.F.1    Herbert, J.2    van Someren, E.J.3    Hodges, J.R.4    Hastings, M.H.5
  • 18
    • 0028865361 scopus 로고
    • Observed sleep/wakefulness and severity of dementia in an Alzheimer's disease special care unit
    • Bliwise, D.L., Hughes, M., McMahon, P.M., Kutner, N., Observed sleep/wakefulness and severity of dementia in an Alzheimer's disease special care unit. J Gerontol Ser A Biol Sci Med Sci 50:6 (1995), M303–M306.
    • (1995) J Gerontol Ser A Biol Sci Med Sci , vol.50 , Issue.6 , pp. M303-M306
    • Bliwise, D.L.1    Hughes, M.2    McMahon, P.M.3    Kutner, N.4
  • 19
    • 0025238507 scopus 로고
    • Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease
    • Witting, W., Kwa, I.H., Eikelenboom, P., Mirmiran, M., Swaab, D.F., Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease. Biol Psychiatry 27:6 (1990), 563–572.
    • (1990) Biol Psychiatry , vol.27 , Issue.6 , pp. 563-572
    • Witting, W.1    Kwa, I.H.2    Eikelenboom, P.3    Mirmiran, M.4    Swaab, D.F.5
  • 20
    • 0035997202 scopus 로고    scopus 로고
    • Age-associated difference in circadian sleep-wake and rest-activity rhythms
    • Huang, Y.L., Liu, R.Y., Wang, Q.S., Van Someren, E.J., Xu, H., Zhou, J.N., Age-associated difference in circadian sleep-wake and rest-activity rhythms. Physiol Behav 76:4–5 (2002), 597–603.
    • (2002) Physiol Behav , vol.76 , Issue.4-5 , pp. 597-603
    • Huang, Y.L.1    Liu, R.Y.2    Wang, Q.S.3    Van Someren, E.J.4    Xu, H.5    Zhou, J.N.6
  • 23
    • 0028918770 scopus 로고
    • Symposium: cognitive processes and sleep disturbances: sleep/wake patterns in Alzheimer's disease: relationships with cognition and function
    • Moe, K.E., Vitiello, M.V., Larsen, L.H., Prinz, P.N., Symposium: cognitive processes and sleep disturbances: sleep/wake patterns in Alzheimer's disease: relationships with cognition and function. J Sleep Res 4:1 (1995), 15–20.
    • (1995) J Sleep Res , vol.4 , Issue.1 , pp. 15-20
    • Moe, K.E.1    Vitiello, M.V.2    Larsen, L.H.3    Prinz, P.N.4
  • 24
    • 0026355073 scopus 로고
    • Sleep problems and institutionalization of the elderly
    • Pollak, C.P., Perlick, D., Sleep problems and institutionalization of the elderly. J Geriatr Psychiatry Neurol 4:4 (1991), 204–210.
    • (1991) J Geriatr Psychiatry Neurol , vol.4 , Issue.4 , pp. 204-210
    • Pollak, C.P.1    Perlick, D.2
  • 25
    • 44949090437 scopus 로고    scopus 로고
    • Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia
    • Harper, D.G., Stopa, E.G., Kuo-Leblanc, V., McKee, A.C., Asayama, K., Volicer, L., et al. Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia. Brain J Neurol 131:Pt. 6 (2008), 1609–1617.
    • (2008) Brain J Neurol , vol.131 , pp. 1609-1617
    • Harper, D.G.1    Stopa, E.G.2    Kuo-Leblanc, V.3    McKee, A.C.4    Asayama, K.5    Volicer, L.6
  • 26
    • 0037244324 scopus 로고    scopus 로고
    • Melatonin rhythmicity: effect of age and Alzheimer's disease
    • Skene, D.J., Swaab, D.F., Melatonin rhythmicity: effect of age and Alzheimer's disease. Exp Gerontol 38:1–2 (2003), 199–206.
    • (2003) Exp Gerontol , vol.38 , Issue.1-2 , pp. 199-206
    • Skene, D.J.1    Swaab, D.F.2
  • 28
    • 0022347706 scopus 로고
    • The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia
    • Swaab, D.F., Fliers, E., Partiman, T.S., The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. Brain Res 342:1 (1985), 37–44.
    • (1985) Brain Res , vol.342 , Issue.1 , pp. 37-44
    • Swaab, D.F.1    Fliers, E.2    Partiman, T.S.3
  • 29
    • 83255175636 scopus 로고    scopus 로고
    • Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women
    • Tranah, G.J., Blackwell, T., Stone, K.L., Ancoli-Israel, S., Paudel, M.L., Ensrud, K.E., et al. Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older women. Ann Neurol 70:5 (2011), 722–732.
    • (2011) Ann Neurol , vol.70 , Issue.5 , pp. 722-732
    • Tranah, G.J.1    Blackwell, T.2    Stone, K.L.3    Ancoli-Israel, S.4    Paudel, M.L.5    Ensrud, K.E.6
  • 30
    • 77951897767 scopus 로고    scopus 로고
    • Systems biology of mammalian circadian clocks
    • Ukai, H., Ueda, H.R., Systems biology of mammalian circadian clocks. Annu Rev Physiol 72 (2010), 579–603.
    • (2010) Annu Rev Physiol , vol.72 , pp. 579-603
    • Ukai, H.1    Ueda, H.R.2
  • 31
    • 0026908395 scopus 로고
    • Behavioral and morphological studies of fetal neural transplants into SCN-lesioned rats
    • Aguilar-Roblero, R., Drucker-Colin, R., Moore, R.Y., Behavioral and morphological studies of fetal neural transplants into SCN-lesioned rats. Chronobiol Int 9:4 (1992), 278–296.
    • (1992) Chronobiol Int , vol.9 , Issue.4 , pp. 278-296
    • Aguilar-Roblero, R.1    Drucker-Colin, R.2    Moore, R.Y.3
  • 32
    • 0024458873 scopus 로고
    • Circadian rhythmicity after neural transplant to hamster third ventricle: specificity of suprachiasmatic nuclei
    • DeCoursey, P.J., Buggy, J., Circadian rhythmicity after neural transplant to hamster third ventricle: specificity of suprachiasmatic nuclei. Brain Res 500:1–2 (1989), 263–275.
    • (1989) Brain Res , vol.500 , Issue.1-2 , pp. 263-275
    • DeCoursey, P.J.1    Buggy, J.2
  • 33
    • 0023265407 scopus 로고
    • Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain
    • Lehman, M.N., Silver, R., Gladstone, W.R., Kahn, R.M., Gibson, M., Bittman, E.L., Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain. J Neurosci Offic J Soc Neurosci 7:6 (1987), 1626–1638.
    • (1987) J Neurosci Offic J Soc Neurosci , vol.7 , Issue.6 , pp. 1626-1638
    • Lehman, M.N.1    Silver, R.2    Gladstone, W.R.3    Kahn, R.M.4    Gibson, M.5    Bittman, E.L.6
  • 34
    • 0025021084 scopus 로고
    • Transplanted suprachiasmatic nucleus determines circadian period
    • Ralph, M.R., Foster, R.G., Davis, F.C., Menaker, M., Transplanted suprachiasmatic nucleus determines circadian period. Science (New York, NY) 247:4945 (1990), 975–978.
    • (1990) Science (New York, NY) , vol.247 , Issue.4945 , pp. 975-978
    • Ralph, M.R.1    Foster, R.G.2    Davis, F.C.3    Menaker, M.4
  • 35
    • 0035914180 scopus 로고    scopus 로고
    • Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections
    • Abrahamson, E.E., Moore, R.Y., Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections. Brain Res 916:1–2 (2001), 172–191.
    • (2001) Brain Res , vol.916 , Issue.1-2 , pp. 172-191
    • Abrahamson, E.E.1    Moore, R.Y.2
  • 36
    • 0019505404 scopus 로고
    • Circadian rhythms in vasopressin deficient rats
    • Groblewski, T.A., Nunez, A.A., Gold, R.M., Circadian rhythms in vasopressin deficient rats. Brain Res Bull 6:2 (1981), 125–130.
    • (1981) Brain Res Bull , vol.6 , Issue.2 , pp. 125-130
    • Groblewski, T.A.1    Nunez, A.A.2    Gold, R.M.3
  • 37
    • 0011871304 scopus 로고
    • Effects of continuous infusion of vasopressin on circadian rhythms of food and water intake, urine output and electrolyte excretion in Brattleboro rats
    • Stoinev, A.G., Ikonomov, O., Effects of continuous infusion of vasopressin on circadian rhythms of food and water intake, urine output and electrolyte excretion in Brattleboro rats. Biulleten' eksperimental'noi biologii i meditsiny 109:2 (1990), 109–111.
    • (1990) Biulleten' eksperimental'noi biologii i meditsiny , vol.109 , Issue.2 , pp. 109-111
    • Stoinev, A.G.1    Ikonomov, O.2
  • 38
    • 0024455660 scopus 로고
    • Vasopressin-deficient rats show a reduced amplitude of the circadian sleep rhythm
    • Brown, M.H., Nunez, A.A., Vasopressin-deficient rats show a reduced amplitude of the circadian sleep rhythm. Physiol Behav 46:4 (1989), 759–762.
    • (1989) Physiol Behav , vol.46 , Issue.4 , pp. 759-762
    • Brown, M.H.1    Nunez, A.A.2
  • 39
    • 20044362444 scopus 로고    scopus 로고
    • Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons
    • Aton, S.J., Colwell, C.S., Harmar, A.J., Waschek, J., Herzog, E.D., Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nat Neurosci 8:4 (2005), 476–483.
    • (2005) Nat Neurosci , vol.8 , Issue.4 , pp. 476-483
    • Aton, S.J.1    Colwell, C.S.2    Harmar, A.J.3    Waschek, J.4    Herzog, E.D.5
  • 40
    • 0035925705 scopus 로고    scopus 로고
    • Effects of neurotensin on discharge rates of rat suprachiasmatic nucleus neurons in vitro
    • Coogan, A.N., Rawlings, N., Luckman, S.M., Piggins, H.D., Effects of neurotensin on discharge rates of rat suprachiasmatic nucleus neurons in vitro. Neuroscience 103:3 (2001), 663–672.
    • (2001) Neuroscience , vol.103 , Issue.3 , pp. 663-672
    • Coogan, A.N.1    Rawlings, N.2    Luckman, S.M.3    Piggins, H.D.4
  • 41
    • 0036979704 scopus 로고    scopus 로고
    • Neurotensin phase-shifts the firing rate rhythm of neurons in the rat suprachiasmatic nuclei in vitro
    • Meyer-Spasche, A., Reed, H.E., Piggins, H.D., Neurotensin phase-shifts the firing rate rhythm of neurons in the rat suprachiasmatic nuclei in vitro. Eur J Neurosci 16:2 (2002), 339–344.
    • (2002) Eur J Neurosci , vol.16 , Issue.2 , pp. 339-344
    • Meyer-Spasche, A.1    Reed, H.E.2    Piggins, H.D.3
  • 42
    • 0032576607 scopus 로고    scopus 로고
    • Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor
    • Alexander, M.J., Leeman, S.E., Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor. J Comp Neurol 402:4 (1998), 475–500.
    • (1998) J Comp Neurol , vol.402 , Issue.4 , pp. 475-500
    • Alexander, M.J.1    Leeman, S.E.2
  • 43
    • 0029784846 scopus 로고    scopus 로고
    • Cellular distribution of neurotensin receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor
    • Boudin, H., Pelaprat, D., Rostene, W., Beaudet, A., Cellular distribution of neurotensin receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor. J Comp Neurol 373:1 (1996), 76–89.
    • (1996) J Comp Neurol , vol.373 , Issue.1 , pp. 76-89
    • Boudin, H.1    Pelaprat, D.2    Rostene, W.3    Beaudet, A.4
  • 44
    • 0026730192 scopus 로고
    • Association of neurotensin receptors with VIP-containing neurons and serotonin-containing axons in the suprachiasmatic nucleus of the rat
    • Francois-Bellan, A.M., Bosler, O., Tonon, M.C., Wei, L.T., Beaudet, A., Association of neurotensin receptors with VIP-containing neurons and serotonin-containing axons in the suprachiasmatic nucleus of the rat. Synapse (New York, NY) 10:4 (1992), 282–290.
    • (1992) Synapse (New York, NY) , vol.10 , Issue.4 , pp. 282-290
    • Francois-Bellan, A.M.1    Bosler, O.2    Tonon, M.C.3    Wei, L.T.4    Beaudet, A.5
  • 46
    • 0015403011 scopus 로고
    • A retinohypothalamic projection in the rat
    • Moore, R.Y., Lenn, N.J., A retinohypothalamic projection in the rat. J Comp Neurol 146:1 (1972), 1–14.
    • (1972) J Comp Neurol , vol.146 , Issue.1 , pp. 1-14
    • Moore, R.Y.1    Lenn, N.J.2
  • 47
    • 22544443993 scopus 로고    scopus 로고
    • Nonphotic entrainment in humans?
    • Mistlberger, R.E., Skene, D.J., Nonphotic entrainment in humans?. J Biol Rhythms 20:4 (2005), 339–352.
    • (2005) J Biol Rhythms , vol.20 , Issue.4 , pp. 339-352
    • Mistlberger, R.E.1    Skene, D.J.2
  • 48
    • 0026772425 scopus 로고
    • Circadian rhythm abnormalities in totally blind people: incidence and clinical significance
    • Sack, R.L., Lewy, A.J., Blood, M.L., Keith, L.D., Nakagawa, H., Circadian rhythm abnormalities in totally blind people: incidence and clinical significance. J Clin Endocrinol Metabol 75:1 (1992), 127–134.
    • (1992) J Clin Endocrinol Metabol , vol.75 , Issue.1 , pp. 127-134
    • Sack, R.L.1    Lewy, A.J.2    Blood, M.L.3    Keith, L.D.4    Nakagawa, H.5
  • 50
    • 0036178045 scopus 로고    scopus 로고
    • Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells
    • Akashi, M., Tsuchiya, Y., Yoshino, T., Nishida, E., Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells. Mol Cell Biol 22:6 (2002), 1693–1703.
    • (2002) Mol Cell Biol , vol.22 , Issue.6 , pp. 1693-1703
    • Akashi, M.1    Tsuchiya, Y.2    Yoshino, T.3    Nishida, E.4
  • 51
    • 43749084373 scopus 로고    scopus 로고
    • Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK
    • Langmesser, S., Tallone, T., Bordon, A., Rusconi, S., Albrecht, U., Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK. BMC Mol Biol 9:1 (2008), 1–16.
    • (2008) BMC Mol Biol , vol.9 , Issue.1 , pp. 1-16
    • Langmesser, S.1    Tallone, T.2    Bordon, A.3    Rusconi, S.4    Albrecht, U.5
  • 52
    • 0037711399 scopus 로고    scopus 로고
    • The circadian clock: pacemaker and tumour suppressor
    • Fu, L., Lee, C.C., The circadian clock: pacemaker and tumour suppressor. Nat Rev Cancer 3:5 (2003), 350–361.
    • (2003) Nat Rev Cancer , vol.3 , Issue.5 , pp. 350-361
    • Fu, L.1    Lee, C.C.2
  • 53
    • 24944460267 scopus 로고    scopus 로고
    • Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors
    • Guillaumond, F., Dardente, H., Giguere, V., Cermakian, N., Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors. J Biol Rhythms 20:5 (2005), 391–403.
    • (2005) J Biol Rhythms , vol.20 , Issue.5 , pp. 391-403
    • Guillaumond, F.1    Dardente, H.2    Giguere, V.3    Cermakian, N.4
  • 54
    • 33749169177 scopus 로고    scopus 로고
    • BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer
    • Kwon, I., Lee, J., Chang, S.H., Jung, N.C., Lee, B.J., Son, G.H., et al. BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer. Mol Cell Biol 26:19 (2006), 7318–7330.
    • (2006) Mol Cell Biol , vol.26 , Issue.19 , pp. 7318-7330
    • Kwon, I.1    Lee, J.2    Chang, S.H.3    Jung, N.C.4    Lee, B.J.5    Son, G.H.6
  • 55
    • 77954867762 scopus 로고    scopus 로고
    • Circadian rhythms and memory formation
    • Gerstner, J.R., Yin, J.C., Circadian rhythms and memory formation. Nat Rev Neurosci 11:8 (2010), 577–588.
    • (2010) Nat Rev Neurosci , vol.11 , Issue.8 , pp. 577-588
    • Gerstner, J.R.1    Yin, J.C.2
  • 56
    • 17244374730 scopus 로고    scopus 로고
    • Caenorhabditis elegans opens up new insights into circadian clock mechanisms
    • Hasegawa, K., Saigusa, T., Tamai, Y., Caenorhabditis elegans opens up new insights into circadian clock mechanisms. Chronobiol Int 22:1 (2005), 1–19.
    • (2005) Chronobiol Int , vol.22 , Issue.1 , pp. 1-19
    • Hasegawa, K.1    Saigusa, T.2    Tamai, Y.3
  • 57
    • 16844370426 scopus 로고    scopus 로고
    • Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation
    • Laposky, A., Easton, A., Dugovic, C., Walisser, J., Bradfield, C., Turek, F., Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation. Sleep 28:4 (2005), 395–409.
    • (2005) Sleep , vol.28 , Issue.4 , pp. 395-409
    • Laposky, A.1    Easton, A.2    Dugovic, C.3    Walisser, J.4    Bradfield, C.5    Turek, F.6
  • 60
    • 77951927020 scopus 로고    scopus 로고
    • Suprachiasmatic nucleus: cell autonomy and network properties
    • Welsh, D.K., Takahashi, J.S., Kay, S.A., Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol 72 (2010), 551–577.
    • (2010) Annu Rev Physiol , vol.72 , pp. 551-577
    • Welsh, D.K.1    Takahashi, J.S.2    Kay, S.A.3
  • 61
    • 0035847577 scopus 로고    scopus 로고
    • The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems
    • Abrahamson, E.E., Leak, R.K., Moore, R.Y., The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems. NeuroReport, 12(2), 2001.
    • (2001) NeuroReport , vol.12 , Issue.2
    • Abrahamson, E.E.1    Leak, R.K.2    Moore, R.Y.3
  • 62
    • 0037987893 scopus 로고    scopus 로고
    • The biological clock tunes the organs of the body: timing by hormones and the autonomic nervous system
    • Buijs, R.M., van Eden, C.G., Goncharuk, V.D., Kalsbeek, A., The biological clock tunes the organs of the body: timing by hormones and the autonomic nervous system. J Endocrinol 177:1 (2003), 17–26.
    • (2003) J Endocrinol , vol.177 , Issue.1 , pp. 17-26
    • Buijs, R.M.1    van Eden, C.G.2    Goncharuk, V.D.3    Kalsbeek, A.4
  • 63
    • 0030759684 scopus 로고    scopus 로고
    • Distribution of vasopressin and vasoactive intestinal polypeptide (VIP) fibers in the human hypothalamus with special emphasis on suprachiasmatic nucleus efferent projections
    • Dai, J., Swaab, D.F., Buijs, R.M., Distribution of vasopressin and vasoactive intestinal polypeptide (VIP) fibers in the human hypothalamus with special emphasis on suprachiasmatic nucleus efferent projections. J Comp Neurol 383:4 (1997), 397–414.
    • (1997) J Comp Neurol , vol.383 , Issue.4 , pp. 397-414
    • Dai, J.1    Swaab, D.F.2    Buijs, R.M.3
  • 64
    • 9244242062 scopus 로고    scopus 로고
    • Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state
    • Deurveilher, S., Semba, K., Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state. Neuroscience 130:1 (2005), 165–183.
    • (2005) Neuroscience , vol.130 , Issue.1 , pp. 165-183
    • Deurveilher, S.1    Semba, K.2
  • 65
    • 0348010253 scopus 로고    scopus 로고
    • Organization of suprachiasmatic nucleus projections in Syrian hamsters (Mesocricetus auratus): an anterograde and retrograde analysis
    • Kriegsfeld, L.J., Leak, R.K., Yackulic, C.B., LeSauter, J., Silver, R.A.E., Organization of suprachiasmatic nucleus projections in Syrian hamsters (Mesocricetus auratus): an anterograde and retrograde analysis. J Comp Neurol 468:3 (2004), 361–379.
    • (2004) J Comp Neurol , vol.468 , Issue.3 , pp. 361-379
    • Kriegsfeld, L.J.1    Leak, R.K.2    Yackulic, C.B.3    LeSauter, J.4    Silver, R.A.E.5
  • 66
    • 14644435678 scopus 로고    scopus 로고
    • The hypothalamic integrator for circadian rhythms
    • Saper, C.B., Lu, J., Chou, T.C., Gooley, J., The hypothalamic integrator for circadian rhythms. Trends Neurosci 28:3 (2005), 152–157.
    • (2005) Trends Neurosci , vol.28 , Issue.3 , pp. 152-157
    • Saper, C.B.1    Lu, J.2    Chou, T.C.3    Gooley, J.4
  • 67
    • 0023105452 scopus 로고
    • Efferent projections of the suprachiasmatic nucleus: II. Studies using retrograde transport of fluorescent dyes and simultaneous peptide immunohistochemistry in the rat
    • Watts, A.G., Swanson, L.W., Efferent projections of the suprachiasmatic nucleus: II. Studies using retrograde transport of fluorescent dyes and simultaneous peptide immunohistochemistry in the rat. J Comp Neurol 258:2 (1987), 230–252.
    • (1987) J Comp Neurol , vol.258 , Issue.2 , pp. 230-252
    • Watts, A.G.1    Swanson, L.W.2
  • 68
    • 0023112513 scopus 로고
    • Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat
    • Watts, A.G., Swanson, L.W., Sanchez-Watts, G., Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. J Comp Neurol 258:2 (1987), 204–229.
    • (1987) J Comp Neurol , vol.258 , Issue.2 , pp. 204-229
    • Watts, A.G.1    Swanson, L.W.2    Sanchez-Watts, G.3
  • 69
    • 0004209977 scopus 로고    scopus 로고
    • The mouse brain in stereotactic coordinates
    • Franklin, K.B.J., Paxinos, G., The mouse brain in stereotactic coordinates. 2008.
    • (2008)
    • Franklin, K.B.J.1    Paxinos, G.2
  • 70
    • 0035399808 scopus 로고    scopus 로고
    • Contrasting effects of Ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep–wake cycle and temperature regulation
    • Lu, J., Zhang, Y.H., Chou, T.C., Gaus, S.E., Elmquist, J.K., Shiromani, P., et al. Contrasting effects of Ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep–wake cycle and temperature regulation. J Neurosci Offic J Soc Neurosci 21:13 (2001), 4864–4874.
    • (2001) J Neurosci Offic J Soc Neurosci , vol.21 , Issue.13 , pp. 4864-4874
    • Lu, J.1    Zhang, Y.H.2    Chou, T.C.3    Gaus, S.E.4    Elmquist, J.K.5    Shiromani, P.6
  • 72
    • 0344011437 scopus 로고    scopus 로고
    • Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms
    • Chou, T.C., Scammell, T.E., Gooley, J.J., Gaus, S.E., Saper, C.B., Lu, J., Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J Neurosci 23:33 (2003), 10691–10702.
    • (2003) J Neurosci , vol.23 , Issue.33 , pp. 10691-10702
    • Chou, T.C.1    Scammell, T.E.2    Gooley, J.J.3    Gaus, S.E.4    Saper, C.B.5    Lu, J.6
  • 73
    • 0029852865 scopus 로고    scopus 로고
    • Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat
    • Thompson, R.H., Canteras, N.S., Swanson, L.W., Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat. J Comp Neurol 376:1 (1996), 143–173.
    • (1996) J Comp Neurol , vol.376 , Issue.1 , pp. 143-173
    • Thompson, R.H.1    Canteras, N.S.2    Swanson, L.W.3
  • 74
    • 13344282764 scopus 로고    scopus 로고
    • Neural control of the pineal gland
    • Moore, R.Y., Neural control of the pineal gland. Behav Brain Res 73:1–2 (1996), 125–130.
    • (1996) Behav Brain Res , vol.73 , Issue.1-2 , pp. 125-130
    • Moore, R.Y.1
  • 75
    • 0033950174 scopus 로고    scopus 로고
    • Morphological heterogeneity of the GABAergic network in the suprachiasmatic nucleus, the brain's circadian pacemaker
    • Castel, M., Morris, J.F., Morphological heterogeneity of the GABAergic network in the suprachiasmatic nucleus, the brain's circadian pacemaker. J Anat 196:Pt. 1 (2000), 1–13.
    • (2000) J Anat , vol.196 , pp. 1-13
    • Castel, M.1    Morris, J.F.2
  • 76
    • 0034669181 scopus 로고    scopus 로고
    • Localization of glutamatergic/aspartatergic neurons projecting to the hypothalamic paraventricular nucleus studied by retrograde transport of [3H]D-aspartate autoradiography
    • Csáki, A., Kocsis, K., Halász, B., Kiss, J., Localization of glutamatergic/aspartatergic neurons projecting to the hypothalamic paraventricular nucleus studied by retrograde transport of [3H]D-aspartate autoradiography. Neuroscience 101:3 (2000), 637–655.
    • (2000) Neuroscience , vol.101 , Issue.3 , pp. 637-655
    • Csáki, A.1    Kocsis, K.2    Halász, B.3    Kiss, J.4
  • 77
    • 0034791539 scopus 로고    scopus 로고
    • Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons
    • Cui, L.-N., Coderre, E., Renaud, L.P., Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons. Am J Physiol Regul Integr Comp Physiol, 281(4), 2001, R1283.
    • (2001) Am J Physiol Regul Integr Comp Physiol , vol.281 , Issue.4 , pp. R1283
    • Cui, L.-N.1    Coderre, E.2    Renaud, L.P.3
  • 78
    • 0033803257 scopus 로고    scopus 로고
    • Melatonin sees the light: blocking GABA-ergic transmission in the paraventricular nucleus induces daytime secretion of melatonin
    • Kalsbeek, A., Garidou, M.-L., Palm, I.F., Van Der Vliet, J., Simonneaux, V., Pévet, P., et al. Melatonin sees the light: blocking GABA-ergic transmission in the paraventricular nucleus induces daytime secretion of melatonin. Eur J Neurosci 12:9 (2000), 3146–3154.
    • (2000) Eur J Neurosci , vol.12 , Issue.9 , pp. 3146-3154
    • Kalsbeek, A.1    Garidou, M.-L.2    Palm, I.F.3    Van Der Vliet, J.4    Simonneaux, V.5    Pévet, P.6
  • 79
    • 0842265631 scopus 로고    scopus 로고
    • Glutamatergic clock output stimulates melatonin synthesis at night
    • Perreau-Lenz, S., Kalsbeek, A., Pévet, P., Buijs, R.M., Glutamatergic clock output stimulates melatonin synthesis at night. Eur J Neurosci 19:2 (2004), 318–324.
    • (2004) Eur J Neurosci , vol.19 , Issue.2 , pp. 318-324
    • Perreau-Lenz, S.1    Kalsbeek, A.2    Pévet, P.3    Buijs, R.M.4
  • 80
    • 4444370704 scopus 로고    scopus 로고
    • Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver
    • Kalsbeek, A., La Fleur, S., Van Heijningen, C., Buijs, R.M., Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver. J Neurosci, 24(35), 2004, 7604.
    • (2004) J Neurosci , vol.24 , Issue.35 , pp. 7604
    • Kalsbeek, A.1    La Fleur, S.2    Van Heijningen, C.3    Buijs, R.M.4
  • 81
    • 0030761518 scopus 로고    scopus 로고
    • Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock
    • Liu, C., Weaver, D.R., Jin, X., Shearman, L.P., Pieschl, R.L., Gribkoff, V.K., et al. Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron 19:1 (1997), 91–102.
    • (1997) Neuron , vol.19 , Issue.1 , pp. 91-102
    • Liu, C.1    Weaver, D.R.2    Jin, X.3    Shearman, L.P.4    Pieschl, R.L.5    Gribkoff, V.K.6
  • 82
    • 0029781519 scopus 로고    scopus 로고
    • A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms
    • Silver, R., LeSauter, J., Tresco, P.A., Lehman, M.N., A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 382:6594 (1996), 810–813.
    • (1996) Nature , vol.382 , Issue.6594 , pp. 810-813
    • Silver, R.1    LeSauter, J.2    Tresco, P.A.3    Lehman, M.N.4
  • 83
    • 0035930732 scopus 로고    scopus 로고
    • Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling
    • Kramer, A., Yang, F.-C., Snodgrass, P., Li, X., Scammell, T.E., Davis, F.C., et al. Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science (New York, NY), 294(5551), 2001, 2511.
    • (2001) Science (New York, NY) , vol.294 , Issue.5551 , pp. 2511
    • Kramer, A.1    Yang, F.-C.2    Snodgrass, P.3    Li, X.4    Scammell, T.E.5    Davis, F.C.6
  • 84
    • 0037161808 scopus 로고    scopus 로고
    • Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus
    • Cheng, M.Y., Bullock, C.M., Li, C., Lee, A.G., Bermak, J.C., Belluzzi, J., et al. Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 417:6887 (2002), 405–410.
    • (2002) Nature , vol.417 , Issue.6887 , pp. 405-410
    • Cheng, M.Y.1    Bullock, C.M.2    Li, C.3    Lee, A.G.4    Bermak, J.C.5    Belluzzi, J.6
  • 85
    • 0001036193 scopus 로고
    • Characteristics of a circadian pacemaker in the suprachiasmatic nucleus
    • Inouye, S.T., Kawamura, H., Characteristics of a circadian pacemaker in the suprachiasmatic nucleus. J Comp Physiol 146:2 (1982), 153–160.
    • (1982) J Comp Physiol , vol.146 , Issue.2 , pp. 153-160
    • Inouye, S.T.1    Kawamura, H.2
  • 86
    • 0018713686 scopus 로고
    • Persistence of circadian rhythmicity in a mammalian hypothalamic “island” containing the suprachiasmatic nucleus
    • Inouye, S.T., Kawamura, H., Persistence of circadian rhythmicity in a mammalian hypothalamic “island” containing the suprachiasmatic nucleus. Proc Natl Acad Sci U S A 76:11 (1979), 5962–5966.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , Issue.11 , pp. 5962-5966
    • Inouye, S.T.1    Kawamura, H.2
  • 87
    • 0021186070 scopus 로고
    • Circadian rhythms in multiple unit activity inside and outside the suprachiasmatic nucleus in the diurnal chipmunk (Eutamias sibiricus)
    • Sato, T., Kawamura, H., Circadian rhythms in multiple unit activity inside and outside the suprachiasmatic nucleus in the diurnal chipmunk (Eutamias sibiricus). Neurosci Res 1:1 (1984), 45–52.
    • (1984) Neurosci Res , vol.1 , Issue.1 , pp. 45-52
    • Sato, T.1    Kawamura, H.2
  • 89
    • 33751380766 scopus 로고    scopus 로고
    • Light and GABAA receptor activation alter period mRNA levels in the SCN of diurnal Nile grass rats
    • Novak, C.M., Ehlen, J.C., Paul, K.N., Fukuhara, C., Albers, H.E., Light and GABAA receptor activation alter period mRNA levels in the SCN of diurnal Nile grass rats. Eur J Neurosci 24:10 (2006), 2843–2852.
    • (2006) Eur J Neurosci , vol.24 , Issue.10 , pp. 2843-2852
    • Novak, C.M.1    Ehlen, J.C.2    Paul, K.N.3    Fukuhara, C.4    Albers, H.E.5
  • 90
    • 14844337870 scopus 로고    scopus 로고
    • Age-related changes in electrophysiological properties of the mouse suprachiasmatic nucleus in vitro
    • Nygard, M., Hill, R.H., Wikstrom, M.A., Kristensson, K., Age-related changes in electrophysiological properties of the mouse suprachiasmatic nucleus in vitro. Brain Res Bull 65:2 (2005), 149–154.
    • (2005) Brain Res Bull , vol.65 , Issue.2 , pp. 149-154
    • Nygard, M.1    Hill, R.H.2    Wikstrom, M.A.3    Kristensson, K.4
  • 91
    • 33646710160 scopus 로고    scopus 로고
    • The aging suprachiasmatic nucleus and cytokines: functional, molecular, and cellular changes in rodents
    • Bentivoglio, M., Deng, X.H., Nygård, M., Sadki, A., Kristensson, K., The aging suprachiasmatic nucleus and cytokines: functional, molecular, and cellular changes in rodents. Chronobiol Int 23:1–2 (2006), 437–449.
    • (2006) Chronobiol Int , vol.23 , Issue.1-2 , pp. 437-449
    • Bentivoglio, M.1    Deng, X.H.2    Nygård, M.3    Sadki, A.4    Kristensson, K.5
  • 92
    • 0032185940 scopus 로고    scopus 로고
    • The significance of circadian organization for longevity in the golden hamster
    • Hurd, M.W., Ralph, M.R., The significance of circadian organization for longevity in the golden hamster. J Biol Rhythms 13:5 (1998), 430–436.
    • (1998) J Biol Rhythms , vol.13 , Issue.5 , pp. 430-436
    • Hurd, M.W.1    Ralph, M.R.2
  • 93
    • 0032430346 scopus 로고    scopus 로고
    • Fetal tissue containing the suprachiasmatic nucleus restores multiple circadian rhythms in old rats
    • Li, H., Satinoff, E., Fetal tissue containing the suprachiasmatic nucleus restores multiple circadian rhythms in old rats. Am J Physiol 275:6 Pt. 2 (1998), R1735–R1744.
    • (1998) Am J Physiol , vol.275 , Issue.6 , pp. R1735-R1744
    • Li, H.1    Satinoff, E.2
  • 94
    • 0028892495 scopus 로고
    • Age and sex do not affect the volume, cell numbers, or cell size of the suprachiasmatic nucleus of the rat: an unbiased stereological study
    • Madeira, M.D., Sousa, N., Santer, R.M., Paula-Barbosa, M.M., Gundersen, H.J., Age and sex do not affect the volume, cell numbers, or cell size of the suprachiasmatic nucleus of the rat: an unbiased stereological study. J Comp Neurol 361:4 (1995), 585–601.
    • (1995) J Comp Neurol , vol.361 , Issue.4 , pp. 585-601
    • Madeira, M.D.1    Sousa, N.2    Santer, R.M.3    Paula-Barbosa, M.M.4    Gundersen, H.J.5
  • 95
    • 14844309309 scopus 로고    scopus 로고
    • Age-related change and its sex differences in histoarchitecture of the hypothalamic suprachiasmatic nucleus of F344/N rats
    • Tsukahara, S., Tanaka, S., Ishida, K., Hoshi, N., Kitagawa, H., Age-related change and its sex differences in histoarchitecture of the hypothalamic suprachiasmatic nucleus of F344/N rats. Exp Gerontol 40:3 (2005), 147–155.
    • (2005) Exp Gerontol , vol.40 , Issue.3 , pp. 147-155
    • Tsukahara, S.1    Tanaka, S.2    Ishida, K.3    Hoshi, N.4    Kitagawa, H.5
  • 96
    • 84856707077 scopus 로고    scopus 로고
    • Neuron numbers in the hypothalamus of the normal aging rhesus monkey: stability across the adult lifespan and between the sexes
    • Roberts, D.E., Killiany, R.J., Rosene, D.L., Neuron numbers in the hypothalamus of the normal aging rhesus monkey: stability across the adult lifespan and between the sexes. J Comp Neurol 520:6 (2012), 1181–1197.
    • (2012) J Comp Neurol , vol.520 , Issue.6 , pp. 1181-1197
    • Roberts, D.E.1    Killiany, R.J.2    Rosene, D.L.3
  • 97
    • 0035139566 scopus 로고    scopus 로고
    • Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study
    • Angelie, E., Bonmartin, A., Boudraa, A., Gonnaud, P.M., Mallet, J.J., Sappey-Marinier, D., Regional differences and metabolic changes in normal aging of the human brain: proton MR spectroscopic imaging study. AJNR Am J Neuroradiol 22:1 (2001), 119–127.
    • (2001) AJNR Am J Neuroradiol , vol.22 , Issue.1 , pp. 119-127
    • Angelie, E.1    Bonmartin, A.2    Boudraa, A.3    Gonnaud, P.M.4    Mallet, J.J.5    Sappey-Marinier, D.6
  • 98
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • Lu, T., Pan, Y., Kao, S.-Y., Li, C., Kohane, I., Chan, J., et al. Gene regulation and DNA damage in the ageing human brain. Nature 429:6994 (2004), 883–891.
    • (2004) Nature , vol.429 , Issue.6994 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.-Y.3    Li, C.4    Kohane, I.5    Chan, J.6
  • 99
    • 0029553607 scopus 로고
    • Age-related differences in synaptosomal membrane fluidity
    • Ohyama, H., Hiramatsu, M., Ogawa, N., Mori, A., Age-related differences in synaptosomal membrane fluidity. Biochem Mol Biol Int 37:1 (1995), 133–140.
    • (1995) Biochem Mol Biol Int , vol.37 , Issue.1 , pp. 133-140
    • Ohyama, H.1    Hiramatsu, M.2    Ogawa, N.3    Mori, A.4
  • 100
    • 0034125199 scopus 로고    scopus 로고
    • Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease
    • Eckert, G.P., Cairns, N.J., Maras, A., Gattaz, W.F., Muller, W.E., Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease. Dementia Geriatr Cognitive Disord 11:4 (2000), 181–186.
    • (2000) Dementia Geriatr Cognitive Disord , vol.11 , Issue.4 , pp. 181-186
    • Eckert, G.P.1    Cairns, N.J.2    Maras, A.3    Gattaz, W.F.4    Muller, W.E.5
  • 101
    • 0020967343 scopus 로고
    • Alterations of the synaptosomal membrane ‘microviscosity’ in the brain cortex of rats during aging and centrophenoxine treatment
    • Nagy, K., Nagy, V., Bertoni-Freddari, C., Nagy, I., Alterations of the synaptosomal membrane ‘microviscosity’ in the brain cortex of rats during aging and centrophenoxine treatment. Archives Gerontol Geriatr 2:1–2 (1983), 23–39.
    • (1983) Archives Gerontol Geriatr , vol.2 , Issue.1-2 , pp. 23-39
    • Nagy, K.1    Nagy, V.2    Bertoni-Freddari, C.3    Nagy, I.4
  • 102
    • 0025865674 scopus 로고
    • Cholesterol modulation of membrane fluidity and VIP receptor/effector system in rat prostatic epithelial cells
    • Carmena, M.J., Hueso, C., Guijarro, L.G., Prieto, J.C., Cholesterol modulation of membrane fluidity and VIP receptor/effector system in rat prostatic epithelial cells. Regul Pept 33:3 (1991), 287–297.
    • (1991) Regul Pept , vol.33 , Issue.3 , pp. 287-297
    • Carmena, M.J.1    Hueso, C.2    Guijarro, L.G.3    Prieto, J.C.4
  • 103
    • 0028837479 scopus 로고
    • N-methyl-D-aspartate receptor density and membrane fluidity as possible determinants of the decline of passive avoidance performance in aging
    • Scheuer, K., Stoll, S., Paschke, U., Weigel, R., Muller, W.E., N-methyl-D-aspartate receptor density and membrane fluidity as possible determinants of the decline of passive avoidance performance in aging. Pharmacol Biochem Behav 50:1 (1995), 65–70.
    • (1995) Pharmacol Biochem Behav , vol.50 , Issue.1 , pp. 65-70
    • Scheuer, K.1    Stoll, S.2    Paschke, U.3    Weigel, R.4    Muller, W.E.5
  • 104
    • 0032939968 scopus 로고    scopus 로고
    • Activation and degeneration during aging: a morphometric study of the human hypothalamus
    • Zhou, J.-N., Swaab, D.F., Activation and degeneration during aging: a morphometric study of the human hypothalamus. Microsc Res Tech 44:1 (1999), 36–48.
    • (1999) Microsc Res Tech , vol.44 , Issue.1 , pp. 36-48
    • Zhou, J.-N.1    Swaab, D.F.2
  • 105
    • 0028260798 scopus 로고
    • Alterations in circadian rhythmicity of the vasopressin-producing neurons of the human suprachiasmatic nucleus (SCN) with aging
    • Hofman, M.A., Swaab, D.F., Alterations in circadian rhythmicity of the vasopressin-producing neurons of the human suprachiasmatic nucleus (SCN) with aging. Brain Res 651:1–2 (1994), 134–142.
    • (1994) Brain Res , vol.651 , Issue.1-2 , pp. 134-142
    • Hofman, M.A.1    Swaab, D.F.2
  • 107
    • 0034033920 scopus 로고    scopus 로고
    • Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression
    • Liu, R.Y., Zhou, J.N., Hoogendijk, W.J., van Heerikhuize, J., Kamphorst, W., Unmehopa, U.A., et al. Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression. J Neuropathol Exp Neurol 59:4 (2000), 314–322.
    • (2000) J Neuropathol Exp Neurol , vol.59 , Issue.4 , pp. 314-322
    • Liu, R.Y.1    Zhou, J.N.2    Hoogendijk, W.J.3    van Heerikhuize, J.4    Kamphorst, W.5    Unmehopa, U.A.6
  • 108
    • 0029121750 scopus 로고
    • VIP neurons in the human SCN in relation to sex, age, and Alzheimer's disease
    • Zhou, J.N., Hofman, M.A., Swaab, D.F., VIP neurons in the human SCN in relation to sex, age, and Alzheimer's disease. Neurobiol Aging 16:4 (1995), 571–576.
    • (1995) Neurobiol Aging , vol.16 , Issue.4 , pp. 571-576
    • Zhou, J.N.1    Hofman, M.A.2    Swaab, D.F.3
  • 110
    • 85018624693 scopus 로고    scopus 로고
    • Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease
    • Yin, Z., Raj, D., Saiepour, N., Van Dam, D., Brouwer, N., Holtman, I.R., et al. Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease. Neurobiol Aging 55 (2017), 115–122.
    • (2017) Neurobiol Aging , vol.55 , pp. 115-122
    • Yin, Z.1    Raj, D.2    Saiepour, N.3    Van Dam, D.4    Brouwer, N.5    Holtman, I.R.6
  • 112
    • 0037376760 scopus 로고    scopus 로고
    • Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease
    • Quinn, J., Montine, T., Morrow, J., Woodward, W.R., Kulhanek, D., Eckenstein, F., Inflammation and cerebral amyloidosis are disconnected in an animal model of Alzheimer's disease. J Neuroimmunol 137:1 (2003), 32–41.
    • (2003) J Neuroimmunol , vol.137 , Issue.1 , pp. 32-41
    • Quinn, J.1    Montine, T.2    Morrow, J.3    Woodward, W.R.4    Kulhanek, D.5    Eckenstein, F.6
  • 113
    • 0035829592 scopus 로고    scopus 로고
    • A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
    • Weggen, S., Eriksen, J.L., Das, P., Sagi, S.A., Wang, R., Pietrzik, C.U., et al. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity. Nature 414:6860 (2001), 212–216.
    • (2001) Nature , vol.414 , Issue.6860 , pp. 212-216
    • Weggen, S.1    Eriksen, J.L.2    Das, P.3    Sagi, S.A.4    Wang, R.5    Pietrzik, C.U.6
  • 114
    • 0024601426 scopus 로고
    • Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease
    • Ogomori, K., Kitamoto, T., Tateishi, J., Sato, Y., Suetsugu, M., Abe, M., Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease. Am J Pathol 134:2 (1989), 243–251.
    • (1989) Am J Pathol , vol.134 , Issue.2 , pp. 243-251
    • Ogomori, K.1    Kitamoto, T.2    Tateishi, J.3    Sato, Y.4    Suetsugu, M.5    Abe, M.6
  • 116
    • 84888204785 scopus 로고    scopus 로고
    • Disruption of neurogenesis by hypothalamic inflammation in obesity or aging
    • Purkayastha, S., Cai, D., Disruption of neurogenesis by hypothalamic inflammation in obesity or aging. Rev Endocr Metabol Disord, 14(4), 2013, 10.1007/s11154-013-9279-z.
    • (2013) Rev Endocr Metabol Disord , vol.14 , Issue.4
    • Purkayastha, S.1    Cai, D.2
  • 117
    • 84877734347 scopus 로고    scopus 로고
    • Hypothalamic programming of systemic aging involving IKKβ/NF-κB and GnRH
    • Zhang, G., Li, J., Purkayastha, S., Tang, Y., Zhang, H., Yin, Y., et al. Hypothalamic programming of systemic aging involving IKKβ/NF-κB and GnRH. Nature 497:7448 (2013), 211–216.
    • (2013) Nature , vol.497 , Issue.7448 , pp. 211-216
    • Zhang, G.1    Li, J.2    Purkayastha, S.3    Tang, Y.4    Zhang, H.5    Yin, Y.6
  • 118
    • 0025756494 scopus 로고
    • Disruption of human circadian and cognitive regulation following a discrete hypothalamic lesion: a case study
    • Cohen, R.A., Albers, E.H., Disruption of human circadian and cognitive regulation following a discrete hypothalamic lesion: a case study. Neurology 41:5 (1991), 726–729.
    • (1991) Neurology , vol.41 , Issue.5 , pp. 726-729
    • Cohen, R.A.1    Albers, E.H.2
  • 119
    • 0022620519 scopus 로고
    • A discrete lesion of ventral hypothalamus and optic chiasm that disturbed the daily temperature rhythm
    • Schwartz, W., Busis, N., Tessa Hedley-Whyte, E., A discrete lesion of ventral hypothalamus and optic chiasm that disturbed the daily temperature rhythm. J Neurol 233:1 (1986), 1–4.
    • (1986) J Neurol , vol.233 , Issue.1 , pp. 1-4
    • Schwartz, W.1    Busis, N.2    Tessa Hedley-Whyte, E.3
  • 120
    • 84867141844 scopus 로고    scopus 로고
    • Lesions of suprachiasmatic nucleus modify sleep structure but do not alter the total amount of daily sleep in rats
    • Liu, X.-G., Zhang, B.-J., Xu, X.-H., Huang, Z.-L., Qu, W.-M., Lesions of suprachiasmatic nucleus modify sleep structure but do not alter the total amount of daily sleep in rats. Sleep Biol Rhythms 10:4 (2012), 293–301.
    • (2012) Sleep Biol Rhythms , vol.10 , Issue.4 , pp. 293-301
    • Liu, X.-G.1    Zhang, B.-J.2    Xu, X.-H.3    Huang, Z.-L.4    Qu, W.-M.5
  • 121
    • 77955714612 scopus 로고    scopus 로고
    • Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 1
    • Sterniczuk, R., Dyck, R.H., Laferla, F.M., Antle, M.C., Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 1. Circadian changes Brain Res 1348 (2010), 139–148.
    • (2010) Circadian changes Brain Res , vol.1348 , pp. 139-148
    • Sterniczuk, R.1    Dyck, R.H.2    Laferla, F.M.3    Antle, M.C.4
  • 124
    • 84865955498 scopus 로고    scopus 로고
    • Disruption of the sleep-wake cycle and diurnal fluctuation of beta-amyloid in mice with Alzheimer's disease pathology
    • 150ra22
    • Roh, J.H., Huang, Y., Bero, A.W., Kasten, T., Stewart, F.R., Bateman, R.J., et al. Disruption of the sleep-wake cycle and diurnal fluctuation of beta-amyloid in mice with Alzheimer's disease pathology. Sci Transl Med, 4(150), 2012 150ra22.
    • (2012) Sci Transl Med , vol.4 , Issue.150
    • Roh, J.H.1    Huang, Y.2    Bero, A.W.3    Kasten, T.4    Stewart, F.R.5    Bateman, R.J.6
  • 126
    • 0036973151 scopus 로고    scopus 로고
    • Effect of melatonin on changes in locomotor activity rhythm of Syrian hamsters injected with beta amyloid peptide 25–35 in the suprachiasmatic nuclei
    • Furio, A.M., Cutrera, R.A., Thea, V.C., Lloret, S.P., Riccio, P., Caccuri, R.L., et al. Effect of melatonin on changes in locomotor activity rhythm of Syrian hamsters injected with beta amyloid peptide 25–35 in the suprachiasmatic nuclei. Cell Mol Neurobiol 22:5 (2002), 699–709.
    • (2002) Cell Mol Neurobiol , vol.22 , Issue.5 , pp. 699-709
    • Furio, A.M.1    Cutrera, R.A.2    Thea, V.C.3    Lloret, S.P.4    Riccio, P.5    Caccuri, R.L.6
  • 127
    • 84897941947 scopus 로고    scopus 로고
    • The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease
    • Chen, K.F., Possidente, B., Lomas, D.A., Crowther, D.C., The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease. Dis Models Mech 7:4 (2014), 445–458.
    • (2014) Dis Models Mech , vol.7 , Issue.4 , pp. 445-458
    • Chen, K.F.1    Possidente, B.2    Lomas, D.A.3    Crowther, D.C.4
  • 128
    • 79955465615 scopus 로고    scopus 로고
    • Glial cells physiologically modulate clock neurons and circadian behavior in a calcium-dependent manner
    • Ng, F.S., Tangredi, M.M., Jackson, F.R., Glial cells physiologically modulate clock neurons and circadian behavior in a calcium-dependent manner. Curr Biol 21:8 (2011), 625–634.
    • (2011) Curr Biol , vol.21 , Issue.8 , pp. 625-634
    • Ng, F.S.1    Tangredi, M.M.2    Jackson, F.R.3
  • 129
    • 79952148685 scopus 로고    scopus 로고
    • Disruption of circadian clocks has ramifications for metabolism, brain, and behavior
    • Karatsoreos, I.N., Bhagat, S., Bloss, E.B., Morrison, J.H., McEwen, B.S., Disruption of circadian clocks has ramifications for metabolism, brain, and behavior. Proc Natl Acad Sci 108:4 (2011), 1657–1662.
    • (2011) Proc Natl Acad Sci , vol.108 , Issue.4 , pp. 1657-1662
    • Karatsoreos, I.N.1    Bhagat, S.2    Bloss, E.B.3    Morrison, J.H.4    McEwen, B.S.5
  • 130
    • 84890015150 scopus 로고    scopus 로고
    • Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
    • Musiek, E.S., Lim, M.M., Yang, G., Bauer, A.Q., Qi, L., Lee, Y., et al. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. J Clin Investig 123:12 (2013), 5389–5400.
    • (2013) J Clin Investig , vol.123 , Issue.12 , pp. 5389-5400
    • Musiek, E.S.1    Lim, M.M.2    Yang, G.3    Bauer, A.Q.4    Qi, L.5    Lee, Y.6
  • 131
    • 0024396397 scopus 로고
    • Abnormal pattern electroretinogram in Alzheimer's disease: evidence for retinal ganglion cell degeneration?
    • Katz, B., Rimmer, S., Iragui, V., Katzman, R., Abnormal pattern electroretinogram in Alzheimer's disease: evidence for retinal ganglion cell degeneration?. Ann Neurol 26:2 (1989), 221–225.
    • (1989) Ann Neurol , vol.26 , Issue.2 , pp. 221-225
    • Katz, B.1    Rimmer, S.2    Iragui, V.3    Katzman, R.4
  • 132
    • 0022497666 scopus 로고
    • Optic-nerve degeneration in Alzheimer's disease
    • Hinton, D.R., Sadun, A.A., Blanks, J.C., Miller, C.A., Optic-nerve degeneration in Alzheimer's disease. N Engl J Med 315:8 (1986), 485–487.
    • (1986) N Engl J Med , vol.315 , Issue.8 , pp. 485-487
    • Hinton, D.R.1    Sadun, A.A.2    Blanks, J.C.3    Miller, C.A.4
  • 133
    • 0033230210 scopus 로고    scopus 로고
    • Is age-related maculopathy associated with Alzheimer's disease? The Rotterdam study
    • Klaver, C.C., Ott, A., Hofman, A., Assink, J.J., Breteler, M.M., de Jong, P.T., Is age-related maculopathy associated with Alzheimer's disease? The Rotterdam study. Am J Epidemiol 150:9 (1999), 963–968.
    • (1999) Am J Epidemiol , vol.150 , Issue.9 , pp. 963-968
    • Klaver, C.C.1    Ott, A.2    Hofman, A.3    Assink, J.J.4    Breteler, M.M.5    de Jong, P.T.6
  • 134
    • 0036206205 scopus 로고    scopus 로고
    • High occurrence rate of glaucoma among patients with Alzheimer's disease
    • Bayer, A.U., Ferrari, F., Erb, C., High occurrence rate of glaucoma among patients with Alzheimer's disease. Eur Neurol 47:3 (2002), 165–168.
    • (2002) Eur Neurol , vol.47 , Issue.3 , pp. 165-168
    • Bayer, A.U.1    Ferrari, F.2    Erb, C.3
  • 135
    • 33744520848 scopus 로고    scopus 로고
    • High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease
    • Tamura, H., Kawakami, H., Kanamoto, T., Kato, T., Yokoyama, T., Sasaki, K., et al. High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease. J Neurolog Sci 246:1–2 (2006), 79–83.
    • (2006) J Neurolog Sci , vol.246 , Issue.1-2 , pp. 79-83
    • Tamura, H.1    Kawakami, H.2    Kanamoto, T.3    Kato, T.4    Yokoyama, T.5    Sasaki, K.6
  • 136
    • 72449167431 scopus 로고    scopus 로고
    • Alzheimer's disease and glaucoma: is there a causal relationship?
    • Wostyn, P., Audenaert, K., De Deyn, P.P., Alzheimer's disease and glaucoma: is there a causal relationship?. Br J Ophthalmol, 93(12), 2009, 1557.
    • (2009) Br J Ophthalmol , vol.93 , Issue.12 , pp. 1557
    • Wostyn, P.1    Audenaert, K.2    De Deyn, P.P.3
  • 137
    • 85017436400 scopus 로고    scopus 로고
    • Alzheimer's disease and glaucoma: can glymphatic system dysfunction underlie their comorbidity?
    • Wostyn, P., De Groot, V., Van Dam, D., Audenaert, K., Killer, H.E., De Deyn, P.P., Alzheimer's disease and glaucoma: can glymphatic system dysfunction underlie their comorbidity?. Acta Ophthalmol 95:3 (2017), e244–e245.
    • (2017) Acta Ophthalmol , vol.95 , Issue.3 , pp. e244-e245
    • Wostyn, P.1    De Groot, V.2    Van Dam, D.3    Audenaert, K.4    Killer, H.E.5    De Deyn, P.P.6
  • 138
    • 31544481443 scopus 로고    scopus 로고
    • Neuropathology of Alzheimer's disease
    • ix
    • Mott, R.T., Hulette, C.M., Neuropathology of Alzheimer's disease. Neuroimaging Clin N Am 15:4 (2005), 755–765 ix.
    • (2005) Neuroimaging Clin N Am , vol.15 , Issue.4 , pp. 755-765
    • Mott, R.T.1    Hulette, C.M.2
  • 139
    • 2142643647 scopus 로고    scopus 로고
    • Basal forebrain neurons modulate the synthesis and expression of neuropeptides in the rat suprachiasmatic nucleus
    • Madeira, M.D., Pereira, P.A., Silva, S.M., Cadete-Leite, A., Paula-Barbosa, M.M., Basal forebrain neurons modulate the synthesis and expression of neuropeptides in the rat suprachiasmatic nucleus. Neuroscience 125:4 (2004), 889–901.
    • (2004) Neuroscience , vol.125 , Issue.4 , pp. 889-901
    • Madeira, M.D.1    Pereira, P.A.2    Silva, S.M.3    Cadete-Leite, A.4    Paula-Barbosa, M.M.5
  • 140
    • 1842734305 scopus 로고    scopus 로고
    • Modulation of photic resetting in rats by lesions of projections to the suprachiasmatic nuclei expressing p75 neurotrophin receptor
    • Erhardt, C., Galani, R., Jeltsch, H., Cassel, J.C., Klosen, P., Menet, J.S., et al. Modulation of photic resetting in rats by lesions of projections to the suprachiasmatic nuclei expressing p75 neurotrophin receptor. Eur J Neurosci 19:7 (2004), 1773–1788.
    • (2004) Eur J Neurosci , vol.19 , Issue.7 , pp. 1773-1788
    • Erhardt, C.1    Galani, R.2    Jeltsch, H.3    Cassel, J.C.4    Klosen, P.5    Menet, J.S.6
  • 141
    • 60249102594 scopus 로고    scopus 로고
    • Cholinergic depletion of the medial septum followed by phase shifting does not impair memory or rest-activity rhythms measured under standard light/dark conditions in rats
    • Craig, L.A., Hong, N.S., Kopp, J., McDonald, R.J., Cholinergic depletion of the medial septum followed by phase shifting does not impair memory or rest-activity rhythms measured under standard light/dark conditions in rats. Brain Res Bull 79:1 (2009), 53–62.
    • (2009) Brain Res Bull , vol.79 , Issue.1 , pp. 53-62
    • Craig, L.A.1    Hong, N.S.2    Kopp, J.3    McDonald, R.J.4
  • 142
    • 1242296774 scopus 로고    scopus 로고
    • Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation
    • Gais, S., Born, J., Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation. Proc Natl Acad Sci U S A 101:7 (2004), 2140–2144.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.7 , pp. 2140-2144
    • Gais, S.1    Born, J.2
  • 143
  • 144
    • 0037247867 scopus 로고    scopus 로고
    • Alterations in the circadian rhythm of salivary melatonin begin during middle-age
    • Zhou, J.-N., Liu, R.-Y., van Heerikhuize, J., Hofman, M.A., Swaab, D.F., Alterations in the circadian rhythm of salivary melatonin begin during middle-age. J Pineal Res 34:1 (2003), 11–16.
    • (2003) J Pineal Res , vol.34 , Issue.1 , pp. 11-16
    • Zhou, J.-N.1    Liu, R.-Y.2    van Heerikhuize, J.3    Hofman, M.A.4    Swaab, D.F.5
  • 145
    • 0032901972 scopus 로고    scopus 로고
    • Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype
    • Liu, R.Y., Zhou, J.N., van Heerikhuize, J., Hofman, M.A., Swaab, D.F., Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer's disease, and apolipoprotein E-epsilon4/4 genotype. J Clin Endocrinol Metabol 84:1 (1999), 323–327.
    • (1999) J Clin Endocrinol Metabol , vol.84 , Issue.1 , pp. 323-327
    • Liu, R.Y.1    Zhou, J.N.2    van Heerikhuize, J.3    Hofman, M.A.4    Swaab, D.F.5
  • 146
    • 34249291586 scopus 로고    scopus 로고
    • Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease
    • Wu, Y.H., Zhou, J.N., Van Heerikhuize, J., Jockers, R., Swaab, D.F., Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease. Neurobiol Aging 28:8 (2007), 1239–1247.
    • (2007) Neurobiol Aging , vol.28 , Issue.8 , pp. 1239-1247
    • Wu, Y.H.1    Zhou, J.N.2    Van Heerikhuize, J.3    Jockers, R.4    Swaab, D.F.5
  • 147
    • 0037344588 scopus 로고    scopus 로고
    • Does melatonin improve sleep in older people? A randomised crossover trial
    • Baskett, J.J., Broad, J.B., Wood, P.C., Duncan, J.R., Pledger, M.J., English, J., et al. Does melatonin improve sleep in older people? A randomised crossover trial. Age Ageing 32:2 (2003), 164–170.
    • (2003) Age Ageing , vol.32 , Issue.2 , pp. 164-170
    • Baskett, J.J.1    Broad, J.B.2    Wood, P.C.3    Duncan, J.R.4    Pledger, M.J.5    English, J.6
  • 148
    • 0031886418 scopus 로고    scopus 로고
    • The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement
    • Hughes, R.J., Sack, R.L., Lewy, A.J., The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement. Sleep 21:1 (1998), 52–68.
    • (1998) Sleep , vol.21 , Issue.1 , pp. 52-68
    • Hughes, R.J.1    Sack, R.L.2    Lewy, A.J.3
  • 149
    • 0031661066 scopus 로고    scopus 로고
    • Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment
    • Jean-Louis, G., von Gizycki, H., Zizi, F., Melatonin effects on sleep, mood, and cognition in elderly with mild cognitive impairment. J Pineal Res 25:3 (1998), 177–183.
    • (1998) J Pineal Res , vol.25 , Issue.3 , pp. 177-183
    • Jean-Louis, G.1    von Gizycki, H.2    Zizi, F.3
  • 152
    • 0033592893 scopus 로고    scopus 로고
    • Rapid down-regulation of mammalian Period genes during behavioral resetting of the circadian clock
    • Maywood, E.S., Mrosovsky, N., Field, M.D., Hastings, M.H., Rapid down-regulation of mammalian Period genes during behavioral resetting of the circadian clock. Proc Natl Acad Sci U S A 96:26 (1999), 15211–15216.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.26 , pp. 15211-15216
    • Maywood, E.S.1    Mrosovsky, N.2    Field, M.D.3    Hastings, M.H.4
  • 153
    • 0034522343 scopus 로고    scopus 로고
    • Illumination levels in nursing home patients: effects on sleep and activity rhythms
    • Shochat, T., Martin, J., Marler, M., Ancoli-Israel, S., Illumination levels in nursing home patients: effects on sleep and activity rhythms. J Sleep Res 9:4 (2000), 373–379.
    • (2000) J Sleep Res , vol.9 , Issue.4 , pp. 373-379
    • Shochat, T.1    Martin, J.2    Marler, M.3    Ancoli-Israel, S.4
  • 154
    • 0347574979 scopus 로고    scopus 로고
    • Increased light exposure consolidates sleep and strengthens circadian rhythms in severe Alzheimer's disease patients
    • Ancoli-Israel, S., Gehrman, P., Martin, J.L., Shochat, T., Marler, M., Corey-Bloom, J., et al. Increased light exposure consolidates sleep and strengthens circadian rhythms in severe Alzheimer's disease patients. Behav Sleep Med 1:1 (2003), 22–36.
    • (2003) Behav Sleep Med , vol.1 , Issue.1 , pp. 22-36
    • Ancoli-Israel, S.1    Gehrman, P.2    Martin, J.L.3    Shochat, T.4    Marler, M.5    Corey-Bloom, J.6
  • 155
    • 0033920638 scopus 로고    scopus 로고
    • Effects of bright light on cognitive and sleep-wake (circadian) rhythm disturbances in Alzheimer-type dementia
    • Yamadera, H., Ito, T., Suzuki, H., Asayama, K., Ito, R., Endo, S., Effects of bright light on cognitive and sleep-wake (circadian) rhythm disturbances in Alzheimer-type dementia. Psychiatry Clin Neurosci 54:3 (2000), 352–353.
    • (2000) Psychiatry Clin Neurosci , vol.54 , Issue.3 , pp. 352-353
    • Yamadera, H.1    Ito, T.2    Suzuki, H.3    Asayama, K.4    Ito, R.5    Endo, S.6
  • 156
    • 84959920978 scopus 로고    scopus 로고
    • Temporal integration of light flashes by the human circadian system
    • Najjar, R.P., Zeitzer, J.M., Temporal integration of light flashes by the human circadian system. J Clin Investig 126:3 (2016), 938–947.
    • (2016) J Clin Investig , vol.126 , Issue.3 , pp. 938-947
    • Najjar, R.P.1    Zeitzer, J.M.2
  • 157
    • 44949175084 scopus 로고    scopus 로고
    • Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial
    • Riemersma-van der Lek, R.F., Swaab, D.F., Twisk, J., Hol, E.M., Hoogendijk, W.J., Van Someren, E.J., Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. Jama 299:22 (2008), 2642–2655.
    • (2008) Jama , vol.299 , Issue.22 , pp. 2642-2655
    • Riemersma-van der Lek, R.F.1    Swaab, D.F.2    Twisk, J.3    Hol, E.M.4    Hoogendijk, W.J.5    Van Someren, E.J.6
  • 158
    • 84915751979 scopus 로고    scopus 로고
    • Clock genes, pancreatic function, and diabetes
    • Vieira, E., Burris, T.P., Quesada, I., Clock genes, pancreatic function, and diabetes. Trends Mol Med 20:12 (2014), 685–693.
    • (2014) Trends Mol Med , vol.20 , Issue.12 , pp. 685-693
    • Vieira, E.1    Burris, T.P.2    Quesada, I.3
  • 159
    • 33750708917 scopus 로고    scopus 로고
    • Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback
    • Fuller, P.M., Gooley, J.J., Saper, C.B., Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback. J Biol Rhythms 21:6 (2006), 482–493.
    • (2006) J Biol Rhythms , vol.21 , Issue.6 , pp. 482-493
    • Fuller, P.M.1    Gooley, J.J.2    Saper, C.B.3


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