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Volumn 214, Issue 11, 2017, Pages 3207-3217

B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD40 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 6; TOLL LIKE RECEPTOR; AUTOANTIBODY;

EID: 85033390839     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20170580     Document Type: Article
Times cited : (188)

References (35)
  • 1
    • 33344475672 scopus 로고    scopus 로고
    • Lymphoid neogenesis in chronic inflammatory diseases
    • Aloisi, F., and R. Pujol-Borrell. 2006. Lymphoid neogenesis in chronic inflammatory diseases. Nat. Rev. Immunol. 6:205-217. http ://dx.doi.org /10.1038 /nri1786
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 205-217
    • Aloisi, F.1    Pujol-Borrell, R.2
  • 5
    • 77953306816 scopus 로고    scopus 로고
    • Preclinical rheumatoid arthritis: Identification, evaluation, and future directions for investigation
    • Deane, K.D., J.M. Norris, and V.M. Holers. 2010. Preclinical rheumatoid arthritis: Identification, evaluation, and future directions for investigation. Rheum. Dis. Clin. North Am. 36:213-241. http ://dx.doi.org /10.1016 /j.rdc.2010.02.001
    • (2010) Rheum. Dis. Clin. North Am , vol.36 , pp. 213-241
    • Deane, K.D.1    Norris, J.M.2    Holers, V.M.3
  • 7
    • 84969132610 scopus 로고    scopus 로고
    • IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity
    • Domeier, P.P., S.B. Chodisetti, C. Soni, S.L. Schell, M.J. Elias, E.B. Wong, T.K. Cooper, D. Kitamura, and Z.S. Rahman. 2016. IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity. J. Exp. Med. 213:715-732. http ://dx.doi.org /10.1084 /jem.20151722
    • (2016) J. Exp. Med , vol.213 , pp. 715-732
    • Domeier, P.P.1    Chodisetti, S.B.2    Soni, C.3    Schell, S.L.4    Elias, M.J.5    Wong, E.B.6    Cooper, T.K.7    Kitamura, D.8    Rahman, Z.S.9
  • 8
    • 79952637807 scopus 로고    scopus 로고
    • IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (TFH) differentiation
    • Eto, D., C. Lao, D. DiToro, B. Barnett, T.C. Escobar, R. Kageyama, I. Yusuf, and S. Crotty. 2011. IL-21 and IL-6 are critical for different aspects of B cell immunity and redundantly induce optimal follicular helper CD4 T cell (TFH) differentiation. PLoS One. 6:e17739. http ://dx.doi.org /10.1371 / journal.pone.0017739
    • (2011) PLoS One , vol.6
    • Eto, D.1    Lao, C.2    DiToro, D.3    Barnett, B.4    Escobar, T.C.5    Kageyama, R.6    Yusuf, I.7    Crotty, S.8
  • 9
    • 84941773482 scopus 로고    scopus 로고
    • B cellspecific MHC class II deletion reveals multiple nonredundant roles for B cell antigen presentation in murine lupus
    • Giles, J.R., M. Kashgarian, P.A. Koni, and M.J. Shlomchik. 2015. B cellspecific MHC class II deletion reveals multiple nonredundant roles for B cell antigen presentation in murine lupus. J. Immunol. 195:2571-2579. http ://dx.doi.org /10.4049 /jimmunol.1500792
    • (2015) J. Immunol , vol.195 , pp. 2571-2579
    • Giles, J.R.1    Kashgarian, M.2    Koni, P.A.3    Shlomchik, M.J.4
  • 10
    • 85033406527 scopus 로고    scopus 로고
    • Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation
    • Giles, J.R., A.T. Neves, A. Marshak-Rothstein, and M.J. Shlomchik. 2017. Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation. JCI Insight. 2:e90870. http ://dx.doi.org /10.1172 /jci.insight.90870
    • (2017) JCI Insight , vol.2
    • Giles, J.R.1    Neves, A.T.2    Marshak-Rothstein, A.3    Shlomchik, M.J.4
  • 12
    • 79952745936 scopus 로고    scopus 로고
    • Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response
    • Hou, B., P. Saudan, G. Ott, M.L. Wheeler, M. Ji, L. Kuzmich, L.M. Lee, R.L. Coffman, M.F. Bachmann, and A.L. DeFranco. 2011. Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity. 34:375-384. http ://dx.doi.org /10.1016 /j.immuni.2011.01.011
    • (2011) Immunity , vol.34 , pp. 375-384
    • Hou, B.1    Saudan, P.2    Ott, G.3    Wheeler, M.L.4    Ji, M.5    Kuzmich, L.6    Lee, L.M.7    Coffman, R.L.8    Bachmann, M.F.9    DeFranco, A.L.10
  • 15
    • 84962911289 scopus 로고    scopus 로고
    • Interleukin 6 accelerates mortality by promoting the progression of the systemic lupus erythematosus-like disease of BXSB.Yaa mice
    • Jain, S., G. Park, T.J. Sproule, G.J. Christianson, C.M. Leeth, H. Wang, D.C. Roopenian, and H.C. Morse III. 2016. Interleukin 6 accelerates mortality by promoting the progression of the systemic lupus erythematosus-like disease of BXSB.Yaa mice. PLoS One. 11:e0153059. http ://dx.doi.org /10.1371 /journal.pone.0153059
    • (2016) PLoS One , vol.11
    • Jain, S.1    Park, G.2    Sproule, T.J.3    Christianson, G.J.4    Leeth, C.M.5    Wang, H.6    Roopenian, D.C.7    Morse, H.C.8
  • 16
    • 0033849422 scopus 로고    scopus 로고
    • Regulation of CD27 expression in the course of germinal center B cell differentiation: The pivotal role of IL-10
    • Jung, J., J. Choe, L. Li, and Y.S. Choi. 2000. Regulation of CD27 expression in the course of germinal center B cell differentiation: The pivotal role of IL-10. Eur. J. Immunol. 30:2437-2443. http ://dx.doi.org /10.1002 /1521-4141(2000)30 :8<2437::AID-IMMU2437>3.0.CO;2-M
    • (2000) Eur. J. Immunol , vol.30 , pp. 2437-2443
    • Jung, J.1    Choe, J.2    Li, L.3    Choi, Y.S.4
  • 17
    • 84870283741 scopus 로고    scopus 로고
    • B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
    • Karnowski, A., S. Chevrier, G.T. Belz, A. Mount, D. Emslie, K. D'Costa, D.M. Tarlinton, A. Kallies, and L.M. Corcoran. 2012. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J. Exp. Med. 209:2049-2064. http ://dx.doi.org /10.1084 /jem.20111504
    • (2012) J. Exp. Med , vol.209 , pp. 2049-2064
    • Karnowski, A.1    Chevrier, S.2    Belz, G.T.3    Mount, A.4    Emslie, D.5    D'Costa, K.6    Tarlinton, D.M.7    Kallies, A.8    Corcoran, L.M.9
  • 18
    • 0032538991 scopus 로고    scopus 로고
    • Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component
    • Kopf, M., S. Herren, M.V. Wiles, M.B. Pepys, and M.H. Kosco-Vilbois. 1998. Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component. J. Exp. Med. 188:1895-1906. http ://dx.doi.org /10.1084 /jem.188.10.1895
    • (1998) J. Exp. Med , vol.188 , pp. 1895-1906
    • Kopf, M.1    Herren, S.2    Wiles, M.V.3    Pepys, M.B.4    Kosco-Vilbois, M.H.5
  • 19
    • 84884321720 scopus 로고    scopus 로고
    • The pathogenesis of lupus nephritis
    • Lech, M., and H.J. Anders. 2013. The pathogenesis of lupus nephritis. J. Am. Soc. Nephrol. 24:1357-1366. http ://dx.doi.org /10.1681 /ASN.2013010026
    • (2013) J. Am. Soc. Nephrol , vol.24 , pp. 1357-1366
    • Lech, M.1    Anders, H.J.2
  • 21
    • 84869213212 scopus 로고    scopus 로고
    • Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers
    • Lee, S.K., D.G. Silva, J.L. Martin, A. Pratama, X. Hu, P.P. Chang, G. Walters, and C.G. Vinuesa. 2012. Interferon-γ excess leads to pathogenic accumulation of follicular helper T cells and germinal centers. Immunity. 37:880-892. http ://dx.doi.org /10.1016 /j.immuni.2012.10.010
    • (2012) Immunity , vol.37 , pp. 880-892
    • Lee, S.K.1    Silva, D.G.2    Martin, J.L.3    Pratama, A.4    Hu, X.5    Chang, P.P.6    Walters, G.7    Vinuesa, C.G.8
  • 23
    • 84992568338 scopus 로고    scopus 로고
    • Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies
    • Lu, R., M.E. Munroe, J.M. Guthridge, K.M. Bean, D.A. Fife, H. Chen, S.R. Slight-Webb, M.P. Keith, J.B. Harley, and J.A. James. 2016. Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies. J. Autoimmun. 74:182-193. http ://dx.doi.org /10.1016 /j.jaut.2016.06.001
    • (2016) J. Autoimmun , vol.74 , pp. 182-193
    • Lu, R.1    Munroe, M.E.2    Guthridge, J.M.3    Bean, K.M.4    Fife, D.A.5    Chen, H.6    Slight-Webb, S.R.7    Keith, M.P.8    Harley, J.B.9    James, J.A.10
  • 24
    • 78751690647 scopus 로고    scopus 로고
    • Human blood CXCR5+CD4+ T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion
    • Morita, R., N. Schmitt, S.E. Bentebibel, R. Ranganathan, L. Bourdery, G. Zurawski, E. Foucat, M. Dullaers, S. Oh, N. Sabzghabaei, et al. 2011. Human blood CXCR5+CD4+ T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity. 34:108-121. http ://dx.doi.org /10.1016 /j.immuni.2010.12.012
    • (2011) Immunity , vol.34 , pp. 108-121
    • Morita, R.1    Schmitt, N.2    Bentebibel, S.E.3    Ranganathan, R.4    Bourdery, L.5    Zurawski, G.6    Foucat, E.7    Dullaers, M.8    Oh, S.9    Sabzghabaei, N.10
  • 25
    • 84962191041 scopus 로고    scopus 로고
    • Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification
    • Munroe, M.E., R. Lu, Y.D. Zhao, D.A. Fife, J.M. Robertson, J.M. Guthridge, T.B. Niewold, G.C. Tsokos, M.P. Keith, J.B. Harley, and J.A. James. 2016. Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification. Ann. Rheum. Dis. 75:2014-2021. http ://dx.doi.org /10.1136 /annrheumdis-2015-208140
    • (2016) Ann. Rheum. Dis , vol.75 , pp. 2014-2021
    • Munroe, M.E.1    Lu, R.2    Zhao, Y.D.3    Fife, D.A.4    Robertson, J.M.5    Guthridge, J.M.6    Niewold, T.B.7    Tsokos, G.C.8    Keith, M.P.9    Harley, J.B.10    James, J.A.11
  • 26
    • 28544449847 scopus 로고    scopus 로고
    • Divergent immunoglobulin g subclass activity through selective Fc receptor binding
    • Nimmerjahn, F., and J.V. Ravetch. 2005. Divergent immunoglobulin g subclass activity through selective Fc receptor binding. Science. 310:1510-1512. http ://dx.doi.org /10.1126 /science.1118948
    • (2005) Science , vol.310 , pp. 1510-1512
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 27
    • 46749151286 scopus 로고    scopus 로고
    • Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
    • Nurieva, R.I., Y. Chung, D. Hwang, X.O. Yang, H.S. Kang, L. Ma, Y.H. Wang, S.S. Watowich, A.M. Jetten, Q. Tian, and C. Dong. 2008. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity. 29:138-149. http ://dx.doi.org /10.1016 /j.immuni.2008.05.009
    • (2008) Immunity , vol.29 , pp. 138-149
    • Nurieva, R.I.1    Chung, Y.2    Hwang, D.3    Yang, X.O.4    Kang, H.S.5    Ma, L.6    Wang, Y.H.7    Watowich, S.S.8    Jetten, A.M.9    Tian, Q.10    Dong, C.11
  • 29
    • 33644750399 scopus 로고    scopus 로고
    • Autoantibodies in diabetes
    • Pihoker, C., L.K. Gilliam, C.S. Hampe, and A. Lernmark. 2005. Autoantibodies in diabetes. Diabetes. 54(Suppl 2):S52-S61. http ://dx.doi.org /10.2337 / diabetes.54.suppl 2.S52
    • (2005) Diabetes , vol.54 , pp. S52-S61
    • Pihoker, C.1    Gilliam, L.K.2    Hampe, C.S.3    Lernmark, A.4
  • 31
    • 0036476551 scopus 로고    scopus 로고
    • Stat1-dependent and-independent pathways in IFN-γ-dependent signaling
    • Ramana, C.V., M.P. Gil, R.D. Schreiber, and G.R. Stark. 2002. Stat1-dependent and-independent pathways in IFN-γ-dependent signaling. Trends Immunol. 23:96-101. http ://dx.doi.org /10.1016 /S1471-4906(01)02118-4
    • (2002) Trends Immunol , vol.23 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3    Stark, G.R.4
  • 33
    • 72949104221 scopus 로고    scopus 로고
    • Dysregulation of germinal centres in autoimmune disease
    • Vinuesa, C.G., I. Sanz, and M.C. Cook. 2009. Dysregulation of germinal centres in autoimmune disease. Nat. Rev. Immunol. 9:845-857. http ://dx.doi.org /10.1038 /nri2637
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 845-857
    • Vinuesa, C.G.1    Sanz, I.2    Cook, M.C.3
  • 35
    • 66249120016 scopus 로고    scopus 로고
    • IL-6 produced by immune complex-activated follicular dendritic cells promotes germinal center reactions, IgG responses and somatic hypermutation
    • Wu, Y., M.E. El Shikh, R.M. El Sayed, A.M. Best, A.K. Szakal, and J.G. Tew. 2009. IL-6 produced by immune complex-activated follicular dendritic cells promotes germinal center reactions, IgG responses and somatic hypermutation. Int. Immunol. 21:745-756. http ://dx.doi.org /10.1093 / intimm /dxp041
    • (2009) Int. Immunol , vol.21 , pp. 745-756
    • Wu, Y.1    El Shikh, M.E.2    El Sayed, R.M.3    Best, A.M.4    Szakal, A.K.5    Tew, J.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.