-
1
-
-
70449106029
-
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
-
Bartholomaus I, et al. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature. 2009;462(7269):94-98.
-
(2009)
Nature.
, vol.462
, Issue.7269
, pp. 94-98
-
-
Bartholomaus, I.1
-
2
-
-
79956116032
-
ROR?T drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
-
Codarri L, et al. ROR?t drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat Immunol. 2011;12(6):560-567.
-
(2011)
Nat Immunol.
, vol.12
, Issue.6
, pp. 560-567
-
-
Codarri, L.1
-
3
-
-
84941735780
-
The cytokine GM-CSF drives the inflammatory signature of CCR2+ monocytes and licenses autoimmunity
-
Croxford AL, et al. The cytokine GM-CSF drives the inflammatory signature of CCR2+ monocytes and licenses autoimmunity. Immunity. 2015;43(3):502-514.
-
(2015)
Immunity.
, vol.43
, Issue.3
, pp. 502-514
-
-
Croxford, A.L.1
-
4
-
-
16244380177
-
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
-
Greter M, et al. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat Med. 2005;11(3):328-334.
-
(2005)
Nat Med.
, vol.11
, Issue.3
, pp. 328-334
-
-
Greter, M.1
-
5
-
-
33846472053
-
CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE
-
Bailey SL, Schreiner B, McMahon EJ, Miller SD. CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE. Nat Immunol. 2007;8(2):172-180.
-
(2007)
Nat Immunol.
, vol.8
, Issue.2
, pp. 172-180
-
-
Bailey, S.L.1
Schreiner, B.2
McMahon, E.J.3
Miller, S.D.4
-
6
-
-
82955228112
-
T(H)17 cytokines in autoimmune neuro-inflammation
-
Becher B, Segal BM. T(H)17 cytokines in autoimmune neuro-inflammation. Curr Opin Immunol. 2011;23(6):707-712.
-
(2011)
Curr Opin Immunol.
, vol.23
, Issue.6
, pp. 707-712
-
-
Becher, B.1
Segal, B.M.2
-
7
-
-
84896522891
-
GM-CSF-responsive monocytederived dendritic cells are pivotal in Th17 pathogenesis
-
Ko HJ, et al. GM-CSF-responsive monocytederived dendritic cells are pivotal in Th17 pathogenesis. J Immunol. 2014;192(5):2202-2209.
-
(2014)
J Immunol.
, vol.192
, Issue.5
, pp. 2202-2209
-
-
Ko, H.J.1
-
8
-
-
84905116959
-
Differential roles of microglia and monocytes in the inflamed central nervous system
-
Yamasaki R, et al. Differential roles of microglia and monocytes in the inflamed central nervous system. J Exp Med. 2014;211(8):1533-1549.
-
(2014)
J Exp Med.
, vol.211
, Issue.8
, pp. 1533-1549
-
-
Yamasaki, R.1
-
9
-
-
84877118165
-
Therapies for multiple sclerosis: Translational achievements and outstanding needs
-
Haghikia A, Hohlfeld R, Gold R, Fugger L. Therapies for multiple sclerosis: translational achievements and outstanding needs. Trends Mol Med. 2013;19(5):309-319.
-
(2013)
Trends Mol Med.
, vol.19
, Issue.5
, pp. 309-319
-
-
Haghikia, A.1
Hohlfeld, R.2
Gold, R.3
Fugger, L.4
-
10
-
-
84926336855
-
Role of the innate and adaptive immune responses in the course of multiple sclerosis
-
Hemmer B, Kerschensteiner M, Korn T. Role of the innate and adaptive immune responses in the course of multiple sclerosis. Lancet Neurol. 2015;14(4):406-419.
-
(2015)
Lancet Neurol.
, vol.14
, Issue.4
, pp. 406-419
-
-
Hemmer, B.1
Kerschensteiner, M.2
Korn, T.3
-
11
-
-
22444450988
-
Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
-
Pluchino S, et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature. 2005;436(7048):266-271.
-
(2005)
Nature.
, vol.436
, Issue.7048
, pp. 266-271
-
-
Pluchino, S.1
-
12
-
-
33745684551
-
The therapeutic potential of neural stem cells
-
Martino G, Pluchino S. The therapeutic potential of neural stem cells. Nat Rev Neurosci. 2006;7(5):395-406.
-
(2006)
Nat Rev Neurosci.
, vol.7
, Issue.5
, pp. 395-406
-
-
Martino, G.1
Pluchino, S.2
-
13
-
-
84860729847
-
Neural stem cell transplantation in central nervous system disorders: From cell replacement to neuroprotection
-
De Feo D, Merlini A, Laterza C, Martino G. Neural stem cell transplantation in central nervous system disorders: from cell replacement to neuroprotection. Curr Opin Neurol. 2012;25(3):322-333.
-
(2012)
Curr Opin Neurol.
, vol.25
, Issue.3
, pp. 322-333
-
-
De Feo, D.1
Merlini, A.2
Laterza, C.3
Martino, G.4
-
14
-
-
84979726329
-
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
-
Pluchino S, et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature. 2003;422(6933):688-694.
-
(2003)
Nature.
, vol.422
, Issue.6933
, pp. 688-694
-
-
Pluchino, S.1
-
15
-
-
19944426191
-
Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1?/CXC chemokine receptor 4 pathway
-
Imitola J, et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1?/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A. 2004;101(52):18117-18122.
-
(2004)
Proc Natl Acad Sci U S A.
, vol.101
, Issue.52
, pp. 18117-18122
-
-
Imitola, J.1
-
16
-
-
67749143855
-
Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms
-
Bacigaluppi M, et al. Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain. 2009;132(pt 8):2239-2251.
-
(2009)
Brain.
, vol.132
, pp. 2239-2251
-
-
Bacigaluppi, M.1
-
17
-
-
84857206115
-
Transplanted neural stem/ precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord
-
Cusimano M, et al. Transplanted neural stem/ precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord. Brain. 2012;135(pt 2):447-460.
-
(2012)
Brain.
, vol.135
, pp. 447-460
-
-
Cusimano, M.1
-
18
-
-
84868207687
-
Neural progenitor cells regulate microglia functions and activity
-
Mosher KI, et al. Neural progenitor cells regulate microglia functions and activity. Nat Neurosci. 2012;15(11):1485-1487.
-
(2012)
Nat Neurosci.
, vol.15
, Issue.11
, pp. 1485-1487
-
-
Mosher, K.I.1
-
19
-
-
80051869587
-
Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease
-
Cao W, et al. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity. 2011;35(2):273-284.
-
(2011)
Immunity.
, vol.35
, Issue.2
, pp. 273-284
-
-
Cao, W.1
-
20
-
-
84949623819
-
Commonalities in immune modulation between mesenchymal stem cells (MSCs) and neural stem/precursor cells (NPCs)
-
Ottoboni L, De Feo D, Merlini A, Martino G. Commonalities in immune modulation between mesenchymal stem cells (MSCs) and neural stem/precursor cells (NPCs). Immunol Lett. 2015;168(2):228-239.
-
(2015)
Immunol Lett.
, vol.168
, Issue.2
, pp. 228-239
-
-
Ottoboni, L.1
De Feo, D.2
Merlini, A.3
Martino, G.4
-
21
-
-
0346494281
-
Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis
-
Einstein O, et al. Intraventricular transplantation of neural precursor cell spheres attenuates acute experimental allergic encephalomyelitis. Mol Cell Neurosci. 2003;24(4):1074-1082.
-
(2003)
Mol Cell Neurosci.
, vol.24
, Issue.4
, pp. 1074-1082
-
-
Einstein, O.1
-
22
-
-
84889249118
-
IPSC-derived neural precursors exert a neuroprotective role in immunemediated demyelination via the secretion of LIF
-
Laterza C, et al. iPSC-derived neural precursors exert a neuroprotective role in immunemediated demyelination via the secretion of LIF. Nat Commun. 2013;4:2597.
-
(2013)
Nat Commun.
, vol.4
, pp. 2597
-
-
Laterza, C.1
-
23
-
-
84905107360
-
Dendritic cells, monocytes and macrophages: A unified nomenclature based on ontogeny
-
Guilliams M, et al. Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol. 2014;14(8):571-578.
-
(2014)
Nat Rev Immunol.
, vol.14
, Issue.8
, pp. 571-578
-
-
Guilliams, M.1
-
24
-
-
84866532132
-
Induction and molecular signature of pathogenic TH17 cells
-
Lee Y, et al. Induction and molecular signature of pathogenic TH17 cells. Nat Immunol. 2012;13(10):991-999.
-
(2012)
Nat Immunol.
, vol.13
, Issue.10
, pp. 991-999
-
-
Lee, Y.1
-
25
-
-
79956152607
-
The encephalitogenicity of T(H)17 cells is dependent on IL-1-and IL-23-induced production of the cytokine GM-CSF
-
El-Behi M, et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1-and IL-23-induced production of the cytokine GM-CSF. Nat Immunol. 2011;12(6):568-575.
-
(2011)
Nat Immunol.
, vol.12
, Issue.6
, pp. 568-575
-
-
El-Behi, M.1
-
26
-
-
84964697743
-
Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress
-
Rissone A, et al. Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress. J Exp Med. 2015;212(8):1185-1202.
-
(2015)
J Exp Med.
, vol.212
, Issue.8
, pp. 1185-1202
-
-
Rissone, A.1
-
27
-
-
82755161784
-
Protein transamidation by transglutaminase 2 in cells: A disputed Ca2+-dependent action of a multifunctional protein
-
Kiraly R, Demeny M, Fesus L. Protein transamidation by transglutaminase 2 in cells: a disputed Ca2+-dependent action of a multifunctional protein. FEBS J. 2011;278(24):4717-4739.
-
(2011)
FEBS J.
, vol.278
, Issue.24
, pp. 4717-4739
-
-
Kiraly, R.1
Demeny, M.2
Fesus, L.3
-
28
-
-
84956883431
-
Novel markers to delineate murine M1 and M2 macrophages
-
Jablonski KA, et al. Novel markers to delineate murine M1 and M2 macrophages. PLoS One. 2015;10(12):e0145342.
-
(2015)
PLoS One.
, vol.10
, Issue.12
, pp. e0145342
-
-
Jablonski, K.A.1
-
29
-
-
14844340837
-
The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages
-
Cao S, Liu J, Song L, Ma X. The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol. 2005;174(6):3484-3492.
-
(2005)
J Immunol.
, vol.174
, Issue.6
, pp. 3484-3492
-
-
Cao, S.1
Liu, J.2
Song, L.3
Ma, X.4
-
30
-
-
81255177676
-
The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation
-
Ahmed N, et al. The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol. 2011;12(12):1176-1183.
-
(2011)
Nat Immunol.
, vol.12
, Issue.12
, pp. 1176-1183
-
-
Ahmed, N.1
-
31
-
-
79959746857
-
Stabilin-1/CLEVER-1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages
-
Palani S, Maksimow M, Miiluniemi M, Auvinen K, Jalkanen S, Salmi M. Stabilin-1/CLEVER-1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages. Eur J Immunol. 2011;41(7):2052-2063.
-
(2011)
Eur J Immunol.
, vol.41
, Issue.7
, pp. 2052-2063
-
-
Palani, S.1
Maksimow, M.2
Miiluniemi, M.3
Auvinen, K.4
Jalkanen, S.5
Salmi, M.6
-
32
-
-
84875658660
-
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: Similarities and differences
-
Martinez FO, et al. Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood. 2013;121(9):e57-e69.
-
(2013)
Blood.
, vol.121
, Issue.9
, pp. e57-e69
-
-
Martinez, F.O.1
-
33
-
-
84893754533
-
DAMP molecule S100A9 acts as a molecular pattern to enhance inflammation during influenza A virus infection: Role of DDX21-TRIF-TLR4-MyD88 pathway
-
Tsai SY, et al. DAMP molecule S100A9 acts as a molecular pattern to enhance inflammation during influenza A virus infection: role of DDX21-TRIF-TLR4-MyD88 pathway. PLoS Pathog. 2014;10(1):e1003848.
-
(2014)
PLoS Pathog.
, vol.10
, Issue.1
, pp. e1003848
-
-
Tsai, S.Y.1
-
34
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue J, et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity. 2014;40(2):274-288.
-
(2014)
Immunity.
, vol.40
, Issue.2
, pp. 274-288
-
-
Xue, J.1
-
35
-
-
71549167047
-
CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
-
Mildner A, et al. CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system. Brain. 2009; 132(pt 9):2487-2500.
-
(2009)
Brain.
, vol.132
, pp. 2487-2500
-
-
Mildner, A.1
-
36
-
-
0035902476
-
A role for CD36 in the regulation of dendritic cell function
-
Urban BC, Willcox N, Roberts DJ. A role for CD36 in the regulation of dendritic cell function. Proc Natl Acad Sci U S A. 2001;98(15):8750-8755.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, Issue.15
, pp. 8750-8755
-
-
Urban, B.C.1
Willcox, N.2
Roberts, D.J.3
-
37
-
-
84880791174
-
NLRP3 inflammasome activation: CD36 serves double duty
-
Kagan JC, Horng T. NLRP3 inflammasome activation: CD36 serves double duty. Nat Immunol. 2013;14(8):772-774.
-
(2013)
Nat Immunol.
, vol.14
, Issue.8
, pp. 772-774
-
-
Kagan, J.C.1
Horng, T.2
-
38
-
-
84920950343
-
IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
-
Cayrol C, Girard JP. IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr Opin Immunol. 2014;31:31-37.
-
(2014)
Curr Opin Immunol.
, vol.31
, pp. 31-37
-
-
Cayrol, C.1
Girard, J.P.2
-
39
-
-
84860007667
-
The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice
-
Zelenay S, et al. The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice. J Clin Invest. 2012;122(5):1615-1627.
-
(2012)
J Clin Invest.
, vol.122
, Issue.5
, pp. 1615-1627
-
-
Zelenay, S.1
-
40
-
-
84859489665
-
Inducible heat shock protein 70 reduces T cell responses and stimulatory capacity of monocyte-derived dendritic cells
-
Stocki P, Wang XN, Dickinson AM. Inducible heat shock protein 70 reduces T cell responses and stimulatory capacity of monocyte-derived dendritic cells. J Biol Chem. 2012;287(15):12387-12394.
-
(2012)
J Biol Chem.
, vol.287
, Issue.15
, pp. 12387-12394
-
-
Stocki, P.1
Wang, X.N.2
Dickinson, A.M.3
-
41
-
-
84925857963
-
IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages
-
Shimizu K, et al. IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages. J Immunol. 2015;194(7):3156-3168.
-
(2015)
J Immunol.
, vol.194
, Issue.7
, pp. 3156-3168
-
-
Shimizu, K.1
-
42
-
-
84948823311
-
A truncated variant of ASCC1, a novel inhibitor of NF-?B, is associated with disease severity in patients with rheumatoid arthritis
-
Torices S, et al. A truncated variant of ASCC1, a novel inhibitor of NF-?B, is associated with disease severity in patients with rheumatoid arthritis. J Immunol. 2015;195(11):5415-5420.
-
(2015)
J Immunol.
, vol.195
, Issue.11
, pp. 5415-5420
-
-
Torices, S.1
-
43
-
-
84855846598
-
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology
-
Pello OM, et al. Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology. Blood. 2012;119(2):411-421.
-
(2012)
Blood.
, vol.119
, Issue.2
, pp. 411-421
-
-
Pello, O.M.1
-
44
-
-
84957800096
-
Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1?-dependent
-
Liu L, et al. Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1?-dependent. Proc Natl Acad Sci U S A. 2016;113(6):1564-1569.
-
(2016)
Proc Natl Acad Sci U S A.
, vol.113
, Issue.6
, pp. 1564-1569
-
-
Liu, L.1
-
45
-
-
84941622047
-
Tumor-induced myeloid deviation: When myeloid-derived suppressor cells meet tumor-associated macrophages
-
Ugel S, De Sanctis F, Mandruzzato S, Bronte V. Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages. J Clin Invest. 2015;125(9):3365-3376.
-
(2015)
J Clin Invest.
, vol.125
, Issue.9
, pp. 3365-3376
-
-
Ugel, S.1
De Sanctis, F.2
Mandruzzato, S.3
Bronte, V.4
-
46
-
-
84878605147
-
PU. 1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment
-
Schonheit J, et al. PU. 1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment. Cell Rep. 2013;3(5):1617-1628.
-
(2013)
Cell Rep.
, vol.3
, Issue.5
, pp. 1617-1628
-
-
Schonheit, J.1
-
47
-
-
84869411578
-
Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-?B pathways
-
Shih VF, et al. Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-?B pathways. Nat Immunol. 2012;13(12):1162-1170.
-
(2012)
Nat Immunol.
, vol.13
, Issue.12
, pp. 1162-1170
-
-
Shih, V.F.1
-
48
-
-
0036500132
-
Functional proteomics of transforming growth factor-?1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGF?1-dependent regulation of DNA repair
-
Kanamoto T, Hellman U, Heldin CH, Souchelnytskyi S. Functional proteomics of transforming growth factor-?1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGF?1-dependent regulation of DNA repair. EMBO J. 2002;21(5):1219-1230.
-
(2002)
EMBO J.
, vol.21
, Issue.5
, pp. 1219-1230
-
-
Kanamoto, T.1
Hellman, U.2
Heldin, C.H.3
Souchelnytskyi, S.4
-
49
-
-
79957969914
-
Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1
-
Leikauf GD, et al. Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. Am J Respir Crit Care Med. 2011;183(11):1499-1509.
-
(2011)
Am J Respir Crit Care Med.
, vol.183
, Issue.11
, pp. 1499-1509
-
-
Leikauf, G.D.1
-
50
-
-
37049000161
-
Role of arginine metabolism in immunity and immunopathology
-
Peranzoni E, et al. Role of arginine metabolism in immunity and immunopathology. Immunobiology. 2007;212(9-10):795-812.
-
(2007)
Immunobiology.
, vol.212
, Issue.910
, pp. 795-812
-
-
Peranzoni, E.1
-
51
-
-
79959713114
-
TGF-? Limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function
-
Rani R, Smulian AG, Greaves DR, Hogan SP, Herbert DR. TGF-? limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. Eur J Immunol. 2011;41(7):2000-2009.
-
(2011)
Eur J Immunol.
, vol.41
, Issue.7
, pp. 2000-2009
-
-
Rani, R.1
Smulian, A.G.2
Greaves, D.R.3
Hogan, S.P.4
Herbert, D.R.5
-
52
-
-
70350445698
-
A CREB-C/EBP? Cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair
-
Ruffell D, et al. A CREB-C/EBP? cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. Proc Natl Acad Sci U S A. 2009;106(41):17475-17480.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, Issue.41
, pp. 17475-17480
-
-
Ruffell, D.1
-
53
-
-
84879103109
-
Macrophage activation and polarization as an adaptive component of innate immunity
-
Locati M, Mantovani A, Sica A. Macrophage activation and polarization as an adaptive component of innate immunity. Adv Immunol. 2013;120:163-184.
-
(2013)
Adv Immunol.
, vol.120
, pp. 163-184
-
-
Locati, M.1
Mantovani, A.2
Sica, A.3
-
54
-
-
67649966553
-
Site-specific anti-tumor immunity: Differences in DC function, TGF-? Production and numbers of intratumoral Foxp3+ Treg
-
Biollaz G, et al. Site-specific anti-tumor immunity: differences in DC function, TGF-? production and numbers of intratumoral Foxp3+ Treg. Eur J Immunol. 2009;39(5):1323-1333.
-
(2009)
Eur J Immunol.
, vol.39
, Issue.5
, pp. 1323-1333
-
-
Biollaz, G.1
-
55
-
-
0030198199
-
TGF-?1 inhibits NF-?B/Rel activity inducing apoptosis of B cells: Transcriptional activation of i kappa B
-
Arsura M, Wu M, Sonenshein GE. TGF-?1 inhibits NF-?B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B?. Immunity. 1996;5(1):31-40.
-
(1996)
Immunity.
, vol.5
, Issue.1
, pp. 31-40
-
-
Arsura, M.1
Wu, M.2
Sonenshein, G.E.3
-
56
-
-
84867290406
-
Dendritic cell-specific disruption of TGF-? Receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity
-
Ramalingam R, et al. Dendritic cell-specific disruption of TGF-? receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity. J Immunol. 2012;189(8):3878-3893.
-
(2012)
J Immunol.
, vol.189
, Issue.8
, pp. 3878-3893
-
-
Ramalingam, R.1
-
57
-
-
41949098657
-
Activin-A: A novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production
-
Robson NC, et al. Activin-A: a novel dendritic cell-derived cytokine that potently attenuates CD40 ligand-specific cytokine and chemokine production. Blood. 2008;111(5):2733-2743.
-
(2008)
Blood.
, vol.111
, Issue.5
, pp. 2733-2743
-
-
Robson, N.C.1
-
58
-
-
84868019450
-
Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice
-
Parsa R, et al. Adoptive transfer of immunomodulatory M2 macrophages prevents type 1 diabetes in NOD mice. Diabetes. 2012;61(11):2881-2892.
-
(2012)
Diabetes.
, vol.61
, Issue.11
, pp. 2881-2892
-
-
Parsa, R.1
-
59
-
-
84864610045
-
Small molecule-mediated TGF-? Type II receptor degradation promotes cardiomyogenesis in embryonic stem cells
-
Willems E, et al. Small molecule-mediated TGF-? type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012;11(2):242-252.
-
(2012)
Cell Stem Cell.
, vol.11
, Issue.2
, pp. 242-252
-
-
Willems, E.1
-
60
-
-
0037100520
-
Induced disruption of the transforming growth factor ? Type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable
-
Leveen P, et al. Induced disruption of the transforming growth factor ? type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable. Blood. 2002;100(2):560-568.
-
(2002)
Blood.
, vol.100
, Issue.2
, pp. 560-568
-
-
Leveen, P.1
-
61
-
-
34447275920
-
Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen
-
Caton ML, Smith-Raska MR, Reizis B. Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen. J Exp Med. 2007;204(7):1653-1664.
-
(2007)
J Exp Med.
, vol.204
, Issue.7
, pp. 1653-1664
-
-
Caton, M.L.1
Smith-Raska, M.R.2
Reizis, B.3
-
62
-
-
0030609894
-
TGF?2 knockout mice have multiple developmental defects that are nonoverlapping with other TGF? Knockout phenotypes
-
Sanford LP, et al. TGF?2 knockout mice have multiple developmental defects that are nonoverlapping with other TGF? knockout phenotypes. Development. 1997;124(13):2659-2670.
-
(1997)
Development.
, vol.124
, Issue.13
, pp. 2659-2670
-
-
Sanford, L.P.1
-
63
-
-
65149093082
-
Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
-
King IL, Dickendesher TL, Segal BM. Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood. 2009;113(14):3190-3197.
-
(2009)
Blood.
, vol.113
, Issue.14
, pp. 3190-3197
-
-
King, I.L.1
Dickendesher, T.L.2
Segal, B.M.3
-
64
-
-
77952982377
-
Induction of inhibitory central nervous system-derived and stimulatory bloodderived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation
-
Hesske L, et al. Induction of inhibitory central nervous system-derived and stimulatory bloodderived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation. Brain. 2010;133(pt 6):1637-1654.
-
(2010)
Brain.
, vol.133
, pp. 1637-1654
-
-
Hesske, L.1
-
65
-
-
0033807680
-
CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis
-
Fife BT, Huffnagle GB, Kuziel WA, Karpus WJ. CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis. J Exp Med. 2000;192(6):899-905.
-
(2000)
J Exp Med.
, vol.192
, Issue.6
, pp. 899-905
-
-
Fife, B.T.1
Huffnagle, G.B.2
Kuziel, W.A.3
Karpus, W.J.4
-
66
-
-
80052246111
-
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
-
Ajami B, Bennett JL, Krieger C, McNagny KM, Rossi FM. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci. 2011;14(9):1142-1149.
-
(2011)
Nat Neurosci.
, vol.14
, Issue.9
, pp. 1142-1149
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
McNagny, K.M.4
Rossi, F.M.5
-
67
-
-
0035476518
-
Granulocyte macrophage colony-stimulating factor: A new putative therapeutic target in multiple sclerosis
-
McQualter JL, et al. Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis. J Exp Med. 2001;194(7):873-882.
-
(2001)
J Exp Med.
, vol.194
, Issue.7
, pp. 873-882
-
-
McQualter, J.L.1
-
68
-
-
33846018916
-
GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis
-
Ponomarev ED, Shriver LP, Maresz K, Pedras-Vasconcelos J, Verthelyi D, Dittel BN. GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis. J Immunol. 2007;178(1):39-48.
-
(2007)
J Immunol.
, vol.178
, Issue.1
, pp. 39-48
-
-
Ponomarev, E.D.1
Shriver, L.P.2
Maresz, K.3
Pedras-Vasconcelos, J.4
Verthelyi, D.5
Dittel, B.N.6
-
69
-
-
0032193230
-
Protection from collageninduced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice
-
Campbell IK, Rich MJ, Bischof RJ, Dunn AR, Grail D, Hamilton JA. Protection from collageninduced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice. J Immunol. 1998;161(7):3639-3644.
-
(1998)
J Immunol.
, vol.161
, Issue.7
, pp. 3639-3644
-
-
Campbell, I.K.1
Rich, M.J.2
Bischof, R.J.3
Dunn, A.R.4
Grail, D.5
Hamilton, J.A.6
-
70
-
-
53349143503
-
GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival
-
Sonderegger I, Iezzi G, Maier R, Schmitz N, Kurrer M, Kopf M. GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival. J Exp Med. 2008;205(10):2281-2294.
-
(2008)
J Exp Med.
, vol.205
, Issue.10
, pp. 2281-2294
-
-
Sonderegger, I.1
Iezzi, G.2
Maier, R.3
Schmitz, N.4
Kurrer, M.5
Kopf, M.6
-
71
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish CL, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med. 2005;201(2):233-240.
-
(2005)
J Exp Med.
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
-
72
-
-
60749107176
-
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
-
McGeachy MJ, et al. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol. 2009;10(3):314-324.
-
(2009)
Nat Immunol.
, vol.10
, Issue.3
, pp. 314-324
-
-
McGeachy, M.J.1
-
73
-
-
84958916856
-
Interleukin-23-induced transcription factor Blimp-1 promotes pathogenicity of T helper 17 cells
-
Jain R, et al. Interleukin-23-induced transcription factor Blimp-1 promotes pathogenicity of T helper 17 cells. Immunity. 2016;44(1):131-142.
-
(2016)
Immunity.
, vol.44
, Issue.1
, pp. 131-142
-
-
Jain, R.1
-
74
-
-
84946149406
-
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
-
Kara EE, et al. CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nat Commun. 2015;6:8644.
-
(2015)
Nat Commun.
, vol.6
, pp. 8644
-
-
Kara, E.E.1
-
75
-
-
84949252174
-
Single-cell genomics unveils critical regulators of Th17 cell pathogenicity
-
Gaublomme JT, et al. Single-cell genomics unveils critical regulators of Th17 cell pathogenicity. Cell. 2015;163(6):1400-1412.
-
(2015)
Cell.
, vol.163
, Issue.6
, pp. 1400-1412
-
-
Gaublomme, J.T.1
-
76
-
-
84879571563
-
Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection
-
Nairz M, et al. Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J Exp Med. 2013;210(5):855-873.
-
(2013)
J Exp Med.
, vol.210
, Issue.5
, pp. 855-873
-
-
Nairz, M.1
-
77
-
-
84917707278
-
Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer
-
Aliper AM, Frieden-Korovkina VP, Buzdin A, Roumiantsev SA, Zhavoronkov A. Interactome analysis of myeloid-derived suppressor cells in murine models of colon and breast cancer. Oncotarget. 2014;5(22):11345-11353.
-
(2014)
Oncotarget.
, vol.5
, Issue.22
, pp. 11345-11353
-
-
Aliper, A.M.1
Frieden-Korovkina, V.P.2
Buzdin, A.3
Roumiantsev, S.A.4
Zhavoronkov, A.5
-
78
-
-
84928884360
-
Id1 suppresses antitumour immune responses and promotes tumour progression by impairing myeloid cell maturation
-
Papaspyridonos M, et al. Id1 suppresses antitumour immune responses and promotes tumour progression by impairing myeloid cell maturation. Nat Commun. 2015;6:6840.
-
(2015)
Nat Commun.
, vol.6
, pp. 6840
-
-
Papaspyridonos, M.1
-
79
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010;141(1):39-51.
-
(2010)
Cell.
, vol.141
, Issue.1
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
80
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill F. Cancer and the chemokine network. Nat Rev Cancer. 2004;4(7):540-550.
-
(2004)
Nat Rev Cancer.
, vol.4
, Issue.7
, pp. 540-550
-
-
Balkwill, F.1
-
81
-
-
84867290406
-
Dendritic cell-specific disruption of TGF-? Receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity
-
Ramalingam R, et al. Dendritic cell-specific disruption of TGF-? receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity. J Immunol. 2012;189(8):3878-3893.
-
(2012)
J Immunol.
, vol.189
, Issue.8
, pp. 3878-3893
-
-
Ramalingam, R.1
-
82
-
-
49449116101
-
TGF-? Signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis
-
Laouar Y, et al. TGF-? signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2008;105(31):10865-10870.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, Issue.31
, pp. 10865-10870
-
-
Laouar, Y.1
-
83
-
-
84904957737
-
TGF-? Signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation
-
Speck S, et al. TGF-? signaling initiated in dendritic cells instructs suppressive effects on Th17 differentiation at the site of neuroinflammation. PLoS One. 2014;9(7):e102390.
-
(2014)
PLoS One.
, vol.9
, Issue.7
, pp. e102390
-
-
Speck, S.1
-
84
-
-
0028982243
-
TGF-?2 decreases migration of lymphocytes in vitro and homing of cells into the central nervous system in vivo
-
Fabry Z, et al. TGF-?2 decreases migration of lymphocytes in vitro and homing of cells into the central nervous system in vivo. J Immunol. 1995;155(1):325-332.
-
(1995)
J Immunol.
, vol.155
, Issue.1
, pp. 325-332
-
-
Fabry, Z.1
-
85
-
-
33846114185
-
Downregulation of transforming growth factor-beta2 facilitates inflammation in the central nervous system by reciprocal astrocyte/ microglia interactions
-
Siglienti I, et al. Downregulation of transforming growth factor-beta2 facilitates inflammation in the central nervous system by reciprocal astrocyte/ microglia interactions. J Neuropathol Exp Neurol. 2007;66(1):47-56.
-
(2007)
J Neuropathol Exp Neurol.
, vol.66
, Issue.1
, pp. 47-56
-
-
Siglienti, I.1
-
86
-
-
0034653933
-
TGF-?2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis
-
Drescher KM, Murray PD, Lin X, Carlino JA, Rodriguez M. TGF-?2 reduces demyelination, virus antigen expression, and macrophage recruitment in a viral model of multiple sclerosis. J Immunol. 2000;164(6):3207-3213.
-
(2000)
J Immunol.
, vol.164
, Issue.6
, pp. 3207-3213
-
-
Drescher, K.M.1
Murray, P.D.2
Lin, X.3
Carlino, J.A.4
Rodriguez, M.5
-
87
-
-
84990854127
-
TGF? Regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells
-
Parsa R, et al. TGF? regulates persistent neuroinflammation by controlling Th1 polarization and ROS production via monocyte-derived dendritic cells. Glia. 2016;64(11):1925-1937.
-
(2016)
Glia.
, vol.64
, Issue.11
, pp. 1925-1937
-
-
Parsa, R.1
-
88
-
-
84978127447
-
The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion
-
Hucke S, et al. The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion. Acta Neuropathol. 2016;132(3):413-431.
-
(2016)
Acta Neuropathol.
, vol.132
, Issue.3
, pp. 413-431
-
-
Hucke, S.1
-
89
-
-
0038523790
-
Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis
-
Bettelli E, Pagany M, Weiner HL, Linington C, Sobel RA, Kuchroo VK. Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. J Exp Med. 2003;197(9):1073-1081.
-
(2003)
J Exp Med.
, vol.197
, Issue.9
, pp. 1073-1081
-
-
Bettelli, E.1
Pagany, M.2
Weiner, H.L.3
Linington, C.4
Sobel, R.A.5
Kuchroo, V.K.6
-
90
-
-
1642445643
-
Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon
-
Tropepe V, Sibilia M, Ciruna BG, Rossant J, Wagner EF, van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Dev Biol. 1999;208(1):166-188.
-
(1999)
Dev Biol.
, vol.208
, Issue.1
, pp. 166-188
-
-
Tropepe, V.1
Sibilia, M.2
Ciruna, B.G.3
Rossant, J.4
Wagner, E.F.5
Van Der Kooy, D.6
-
91
-
-
67650155553
-
Immune regulatory neural stem/ precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function
-
Pluchino S, et al. Immune regulatory neural stem/ precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function. PLoS One. 2009;4(6):e5959.
-
(2009)
PLoS One.
, vol.4
, Issue.6
, pp. e5959
-
-
Pluchino, S.1
-
92
-
-
4444261780
-
HMGB1 is an endogenous immune adjuvant released by necrotic cells
-
Rovere-Querini P, et al. HMGB1 is an endogenous immune adjuvant released by necrotic cells. EMBO Rep. 2004;5(8):825-830.
-
(2004)
EMBO Rep.
, vol.5
, Issue.8
, pp. 825-830
-
-
Rovere-Querini, P.1
-
93
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 2010;330(6005):841-845.
-
(2010)
Science.
, vol.330
, Issue.6005
, pp. 841-845
-
-
Ginhoux, F.1
|