Computational design of environmental sensors for the potent opioid fentanyl

eLife

Volumn 6, Issue , 2017, Pages

  Bick, Matthew J ^a   Greisen, Per J ^a   Morey, Kevin J ^b   Antunes, Mauricio S ^b   La, David ^a   Sankaran, Banumathi ^c   Reymond, Luc ^d,e   Johnsson, Kai ^d,e   Medford, June I ^b   Baker, David ^a,f  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d EPFL   (Switzerland)

^e MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^f UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBENICILLIN; COMPLEMENTARY DNA; GLUCOSE; KANAMYCIN; MOLECULAR SCAFFOLD; OPIATE AGONIST; OPIOID FENTANYL; UNCLASSIFIED DRUG; FENTANYL; MEMBRANE PROTEIN; NARCOTIC AGENT; PROTEIN BINDING; RECOMBINANT PROTEIN;

ALGORITHM; ANISOTROPY; ARABIDOPSIS; ARTICLE; BINDING AFFINITY; BIOLOGY; BIOTINYLATION; CHEMICAL PHENOMENA; CHROMOPHORE ASSISTED LIGHT INACTIVATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DNA BINDING; ENVIRONMENTAL FACTOR; GENE FREQUENCY; GENE MUTATION; GEOMETRY; HYDROGEN BOND; LIMIT OF QUANTITATION; LUCIFERASE ASSAY; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PROBABILITY; PROTEIN EXPRESSION; QUADRUPOLE MASS SPECTROMETRY; SCORING SYSTEM; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SOFTWARE; CHEMISTRY; GENE EXPRESSION; GENETICS; METABOLISM; PROCEDURES; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; X RAY CRYSTALLOGRAPHY;

COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; FENTANYL; GENE EXPRESSION; MEMBRANE PROTEINS; NARCOTICS; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 85032909293     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.28909     Document Type: Article

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