-
1
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
Paolicelli, R.C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., Ferreira, T.A., Guiducci, E., Dumas, L., et al. Synaptic pruning by microglia is necessary for normal brain development. Science 333 (2011), 1456–1458.
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
Bolasco, G.2
Pagani, F.3
Maggi, L.4
Scianni, M.5
Panzanelli, P.6
Giustetto, M.7
Ferreira, T.A.8
Guiducci, E.9
Dumas, L.10
-
2
-
-
84861427387
-
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
-
Schafer, D.P., Lehrman, E.K., Kautzman, A.G., Koyama, R., Mardinly, A.R., Yamasaki, R., Ransohoff, R.M., Greenberg, M.E., Barres, B.A., Stevens, B., Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron 74 (2012), 691–705.
-
(2012)
Neuron
, vol.74
, pp. 691-705
-
-
Schafer, D.P.1
Lehrman, E.K.2
Kautzman, A.G.3
Koyama, R.4
Mardinly, A.R.5
Yamasaki, R.6
Ransohoff, R.M.7
Greenberg, M.E.8
Barres, B.A.9
Stevens, B.10
-
3
-
-
36849076770
-
The classical complement cascade mediates CNS synapse elimination
-
Stevens, B., Allen, N.J., Vazquez, L.E., Howell, G.R., Christopherson, K.S., Nouri, N., Micheva, K.D., Mehalow, A.K., Huberman, A.D., Stafford, B., The classical complement cascade mediates CNS synapse elimination. Cell, 131, 2007, 1164.
-
(2007)
Cell
, vol.131
, pp. 1164
-
-
Stevens, B.1
Allen, N.J.2
Vazquez, L.E.3
Howell, G.R.4
Christopherson, K.S.5
Nouri, N.6
Micheva, K.D.7
Mehalow, A.K.8
Huberman, A.D.9
Stafford, B.10
-
4
-
-
84888348687
-
TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement
-
Bialas, A.R., Stevens, B., TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement. Nat Neurosci 16 (2013), 1773–1782.
-
(2013)
Nat Neurosci
, vol.16
, pp. 1773-1782
-
-
Bialas, A.R.1
Stevens, B.2
-
5
-
-
73949103664
-
C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production
-
Fraser, D.A., Pisalyaput, K., Tenner, A.J., C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production. J Neurochem 112 (2010), 733–743.
-
(2010)
J Neurochem
, vol.112
, pp. 733-743
-
-
Fraser, D.A.1
Pisalyaput, K.2
Tenner, A.J.3
-
6
-
-
14244268775
-
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
-
Takahashi, K., Rochford, C.D., Neumann, H., Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J Exp Med 201 (2005), 647–657.
-
(2005)
J Exp Med
, vol.201
, pp. 647-657
-
-
Takahashi, K.1
Rochford, C.D.2
Neumann, H.3
-
7
-
-
51149091666
-
Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor
-
Wakselman, S., Bechade, C., Roumier, A., Bernard, D., Triller, A., Bessis, A., Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor. J Neurosci 28 (2008), 8138–8143.
-
(2008)
J Neurosci
, vol.28
, pp. 8138-8143
-
-
Wakselman, S.1
Bechade, C.2
Roumier, A.3
Bernard, D.4
Triller, A.5
Bessis, A.6
-
8
-
-
84894574217
-
Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor
-
Parkhurst, C.N., Yang, G., Ninan, I., Savas, J.N., Yates, J.R. 3rd, Lafaille, J.J., Hempstead, B.L., Littman, D.R., Gan, W.B., Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell 155 (2013), 1596–1609.
-
(2013)
Cell
, vol.155
, pp. 1596-1609
-
-
Parkhurst, C.N.1
Yang, G.2
Ninan, I.3
Savas, J.N.4
Yates, J.R.5
Lafaille, J.J.6
Hempstead, B.L.7
Littman, D.R.8
Gan, W.B.9
-
9
-
-
36048932754
-
A dual role for interleukin-1 in hippocampal-dependent memory processes
-
Goshen, I., Kreisel, T., Ounallah-Saad, H., Renbaum, P., Zalzstein, Y., Ben-Hur, T., Levy-Lahad, E., Yirmiya, R., A dual role for interleukin-1 in hippocampal-dependent memory processes. Psychoneuroendocrinology 32 (2007), 1106–1115.
-
(2007)
Psychoneuroendocrinology
, vol.32
, pp. 1106-1115
-
-
Goshen, I.1
Kreisel, T.2
Ounallah-Saad, H.3
Renbaum, P.4
Zalzstein, Y.5
Ben-Hur, T.6
Levy-Lahad, E.7
Yirmiya, R.8
-
10
-
-
84922519429
-
Microglia modulate wiring of the embryonic forebrain
-
Microglia modulate outgrowth of dopaminergic axons and the laminar positioning of subsets of neocortical interneurons during embryonic forebrain formation. This microglia activity is dependent on Cx3cr1 signaling.
-
Squarzoni, P., Oller, G., Hoeffel, G., Pont-Lezica, L., Rostaing, P., Low, D., Bessis, A., Ginhoux, F., Garel, S., Microglia modulate wiring of the embryonic forebrain. Cell Rep 8 (2014), 1271–1279 Microglia modulate outgrowth of dopaminergic axons and the laminar positioning of subsets of neocortical interneurons during embryonic forebrain formation. This microglia activity is dependent on Cx3cr1 signaling.
-
(2014)
Cell Rep
, vol.8
, pp. 1271-1279
-
-
Squarzoni, P.1
Oller, G.2
Hoeffel, G.3
Pont-Lezica, L.4
Rostaing, P.5
Low, D.6
Bessis, A.7
Ginhoux, F.8
Garel, S.9
-
11
-
-
84876939061
-
Layer V cortical neurons require microglial support for survival during postnatal development
-
Ueno, M., Fujita, Y., Tanaka, T., Nakamura, Y., Kikuta, J., Ishii, M., Yamashita, T., Layer V cortical neurons require microglial support for survival during postnatal development. Nat Neurosci 16 (2013), 543–551.
-
(2013)
Nat Neurosci
, vol.16
, pp. 543-551
-
-
Ueno, M.1
Fujita, Y.2
Tanaka, T.3
Nakamura, Y.4
Kikuta, J.5
Ishii, M.6
Yamashita, T.7
-
12
-
-
0031934936
-
Microglia-derived nerve growth factor causes cell death in the developing retina
-
Frade, J.M., Barde, Y.A., Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 20 (1998), 35–41.
-
(1998)
Neuron
, vol.20
, pp. 35-41
-
-
Frade, J.M.1
Barde, Y.A.2
-
13
-
-
84899418705
-
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
-
Prinz, M., Priller, J., Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease. Nat Rev Neurosci 15 (2014), 300–312.
-
(2014)
Nat Rev Neurosci
, vol.15
, pp. 300-312
-
-
Prinz, M.1
Priller, J.2
-
14
-
-
84943279510
-
Microglia function in central nervous system development and plasticity
-
Schafer, D.P., Stevens, B., Microglia function in central nervous system development and plasticity. Cold Spring Harb Perspect Biol, 7, 2015, a020545.
-
(2015)
Cold Spring Harb Perspect Biol
, vol.7
, pp. a020545
-
-
Schafer, D.P.1
Stevens, B.2
-
15
-
-
84896692474
-
Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior
-
Zhan, Y., Paolicelli, R.C., Sforazzini, F., Weinhard, L., Bolasco, G., Pagani, F., Vyssotski, A.L., Bifone, A., Gozzi, A., Ragozzino, D., Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior. Nat Neurosci, 17, 2014, 400.
-
(2014)
Nat Neurosci
, vol.17
, pp. 400
-
-
Zhan, Y.1
Paolicelli, R.C.2
Sforazzini, F.3
Weinhard, L.4
Bolasco, G.5
Pagani, F.6
Vyssotski, A.L.7
Bifone, A.8
Gozzi, A.9
Ragozzino, D.10
-
16
-
-
84868212781
-
The immune system and developmental programming of brain and behavior
-
Bilbo, S.D., Schwarz, J.M., The immune system and developmental programming of brain and behavior. Front Neuroendocrinol 33 (2012), 267–286.
-
(2012)
Front Neuroendocrinol
, vol.33
, pp. 267-286
-
-
Bilbo, S.D.1
Schwarz, J.M.2
-
17
-
-
84860744795
-
A lifespan approach to neuroinflammatory and cognitive disorders: a critical role for glia
-
Bilbo, S.D., Smith, S.H., Schwarz, J.M., A lifespan approach to neuroinflammatory and cognitive disorders: a critical role for glia. J Neuroimmune Pharmacol, 2011.
-
(2011)
J Neuroimmune Pharmacol
-
-
Bilbo, S.D.1
Smith, S.H.2
Schwarz, J.M.3
-
18
-
-
24344478174
-
Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition
-
Bilbo, S.D., Biedenkapp, J.C., Der-Avakian, A., Watkins, L.R., Rudy, J.W., Maier, S.F., Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. J Neurosci 25 (2005), 8000–8009.
-
(2005)
J Neurosci
, vol.25
, pp. 8000-8009
-
-
Bilbo, S.D.1
Biedenkapp, J.C.2
Der-Avakian, A.3
Watkins, L.R.4
Rudy, J.W.5
Maier, S.F.6
-
19
-
-
77953521826
-
Enduring consequences of maternal obesity for brain inflammation and behavior of offspring
-
Bilbo, S.D., Tsang, V., Enduring consequences of maternal obesity for brain inflammation and behavior of offspring. FASEB J 24 (2010), 2104–2115.
-
(2010)
FASEB J
, vol.24
, pp. 2104-2115
-
-
Bilbo, S.D.1
Tsang, V.2
-
20
-
-
80054921191
-
Microglia and memory: modulation by early-life infection
-
Williamson, L.L., Sholar, P.W., Mistry, R.S., Smith, S.H., Bilbo, S.D., Microglia and memory: modulation by early-life infection. J Neurosci 31 (2011), 15511–15521.
-
(2011)
J Neurosci
, vol.31
, pp. 15511-15521
-
-
Williamson, L.L.1
Sholar, P.W.2
Mistry, R.S.3
Smith, S.H.4
Bilbo, S.D.5
-
21
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M.F., Conway, S.J., Ng, L.G., Stanley, E.R., et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (New York, N.Y.) 330 (2010), 841–845.
-
(2010)
Science (New York, N.Y.)
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
Mehler, M.F.7
Conway, S.J.8
Ng, L.G.9
Stanley, E.R.10
-
22
-
-
84875892857
-
Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
-
Kierdorf, K., Erny, D., Goldmann, T., Sander, V., Schulz, C., Perdiguero, E.G., Wieghofer, P., Heinrich, A., Riemke, P., Hölscher, C., Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci, 16, 2013, 273.
-
(2013)
Nat Neurosci
, vol.16
, pp. 273
-
-
Kierdorf, K.1
Erny, D.2
Goldmann, T.3
Sander, V.4
Schulz, C.5
Perdiguero, E.G.6
Wieghofer, P.7
Heinrich, A.8
Riemke, P.9
Hölscher, C.10
-
23
-
-
85032230436
-
On place and time: microglia in embryonic and perinatal brain development
-
(in press)
-
Thion, M.S., Garel, S., On place and time: microglia in embryonic and perinatal brain development. Curr Opin Neurobiol, 47, 2017, 10.1016/j.conb.2017.10.004 (in press).
-
(2017)
Curr Opin Neurobiol
, vol.47
-
-
Thion, M.S.1
Garel, S.2
-
24
-
-
84898676953
-
Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain
-
Elmore, M.R., Najafi, A.R., Koike, M.A., Dagher, N.N., Spangenberg, E.E., Rice, R.A., Kitazawa, M., Matusow, B., Nguyen, H., West, B.L., et al. Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain. Neuron 82 (2014), 380–397.
-
(2014)
Neuron
, vol.82
, pp. 380-397
-
-
Elmore, M.R.1
Najafi, A.R.2
Koike, M.A.3
Dagher, N.N.4
Spangenberg, E.E.5
Rice, R.A.6
Kitazawa, M.7
Matusow, B.8
Nguyen, H.9
West, B.L.10
-
25
-
-
84859508307
-
A lineage of myeloid cells independent of Myb and hematopoietic stem cells
-
Schulz, C., Gomez Perdiguero, E., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S.E., Pollard, J.W., et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336 (2012), 86–90.
-
(2012)
Science
, vol.336
, pp. 86-90
-
-
Schulz, C.1
Gomez Perdiguero, E.2
Chorro, L.3
Szabo-Rogers, H.4
Cagnard, N.5
Kierdorf, K.6
Prinz, M.7
Wu, B.8
Jacobsen, S.E.9
Pollard, J.W.10
-
26
-
-
79959964671
-
Maternal infection and immune involvement in autism
-
Patterson, P.H., Maternal infection and immune involvement in autism. Trends Mol Med 17 (2011), 389–394.
-
(2011)
Trends Mol Med
, vol.17
, pp. 389-394
-
-
Patterson, P.H.1
-
27
-
-
39049150319
-
The risk for schizophrenia from childhood and adult infections
-
Brown, A.S., The risk for schizophrenia from childhood and adult infections. Am J Psychiatry 165 (2008), 7–10.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 7-10
-
-
Brown, A.S.1
-
28
-
-
43749086873
-
Maternal infection during pregnancy and schizophrenia
-
Boksa, P., Maternal infection during pregnancy and schizophrenia. J Psychiatry Neurosci 33 (2008), 183–185.
-
(2008)
J Psychiatry Neurosci
, vol.33
, pp. 183-185
-
-
Boksa, P.1
-
29
-
-
39049118349
-
Infections in the CNS during childhood and the risk of subsequent psychotic illness: a cohort study of more than one million Swedish subjects
-
Dalman, C., Allebeck, P., Gunnell, D., Harrison, G., Kristensson, K., Lewis, G., Lofving, S., Rasmussen, F., Wicks, S., Karlsson, H., Infections in the CNS during childhood and the risk of subsequent psychotic illness: a cohort study of more than one million Swedish subjects. Am J Psychiatry 165 (2008), 59–65.
-
(2008)
Am J Psychiatry
, vol.165
, pp. 59-65
-
-
Dalman, C.1
Allebeck, P.2
Gunnell, D.3
Harrison, G.4
Kristensson, K.5
Lewis, G.6
Lofving, S.7
Rasmussen, F.8
Wicks, S.9
Karlsson, H.10
-
30
-
-
84864520051
-
Modeling an autism risk factor in mice leads to permanent immune dysregulation
-
Hsiao, E.Y., McBride, S.W., Chow, J., Mazmanian, S.K., Patterson, P.H., Modeling an autism risk factor in mice leads to permanent immune dysregulation. Proc Natl Acad Sci U S A 109 (2012), 12776–12781.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 12776-12781
-
-
Hsiao, E.Y.1
McBride, S.W.2
Chow, J.3
Mazmanian, S.K.4
Patterson, P.H.5
-
31
-
-
67749114055
-
Immune involvement in schizophrenia and autism: etiology, pathology and animal models
-
Patterson, P.H., Immune involvement in schizophrenia and autism: etiology, pathology and animal models. Behav Brain Res 204 (2009), 313–321.
-
(2009)
Behav Brain Res
, vol.204
, pp. 313-321
-
-
Patterson, P.H.1
-
32
-
-
0037218688
-
Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring
-
Shi, L., Fatemi, S.H., Sidwell, R.W., Patterson, P.H., Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci 23 (2003), 297–302.
-
(2003)
J Neurosci
, vol.23
, pp. 297-302
-
-
Shi, L.1
Fatemi, S.H.2
Sidwell, R.W.3
Patterson, P.H.4
-
33
-
-
56949092229
-
Activation of the maternal immune system alters cerebellar development in the offspring
-
Shi, L., Smith, S.E., Malkova, N., Tse, D., Su, Y., Patterson, P.H., Activation of the maternal immune system alters cerebellar development in the offspring. Brain Behav Immun 23 (2009), 116–123.
-
(2009)
Brain Behav Immun
, vol.23
, pp. 116-123
-
-
Shi, L.1
Smith, S.E.2
Malkova, N.3
Tse, D.4
Su, Y.5
Patterson, P.H.6
-
34
-
-
85030631674
-
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring
-
Kim, S., Kim, H., Yim, Y.S., Ha, S., Atarashi, K., Tan, T.G., Longman, R.S., Honda, K., Littman, D.R., Choi, G.B., et al. Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring. Nature, 2017.
-
(2017)
Nature
-
-
Kim, S.1
Kim, H.2
Yim, Y.S.3
Ha, S.4
Atarashi, K.5
Tan, T.G.6
Longman, R.S.7
Honda, K.8
Littman, D.R.9
Choi, G.B.10
-
35
-
-
85030630920
-
Reversing behavioural abnormalities in mice exposed to maternal inflammation
-
Shin Yim, Y., Park, A., Berrios, J., Lafourcade, M., Pascual, L.M., Soares, N., Yeon Kim, J., Kim, S., Kim, H., Waisman, A., et al. Reversing behavioural abnormalities in mice exposed to maternal inflammation. Nature, 2017.
-
(2017)
Nature
-
-
Shin Yim, Y.1
Park, A.2
Berrios, J.3
Lafourcade, M.4
Pascual, L.M.5
Soares, N.6
Yeon Kim, J.7
Kim, S.8
Kim, H.9
Waisman, A.10
-
36
-
-
84959447961
-
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
-
Choi, G.B., Yim, Y.S., Wong, H., Kim, S., Kim, H., Kim, S.V., Hoeffer, C.A., Littman, D.R., Huh, J.R., The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science 351 (2016), 933–939.
-
(2016)
Science
, vol.351
, pp. 933-939
-
-
Choi, G.B.1
Yim, Y.S.2
Wong, H.3
Kim, S.4
Kim, H.5
Kim, S.V.6
Hoeffer, C.A.7
Littman, D.R.8
Huh, J.R.9
-
37
-
-
85032389769
-
Associations between maternal cytokine levels during gestation and child neurodevelopment
-
(in press)
-
Dozmorov, M.K., Bilbo, S.D., Kollins, S., Zucker, N., Schechter, J.C., Do, E.K., Zhang, J., Murphy, S., Hoyo, C., Fuemmeler, B.F., Associations between maternal cytokine levels during gestation and child neurodevelopment. Brain Behav Immun, 2017 (in press).
-
(2017)
Brain Behav Immun
-
-
Dozmorov, M.K.1
Bilbo, S.D.2
Kollins, S.3
Zucker, N.4
Schechter, J.C.5
Do, E.K.6
Zhang, J.7
Murphy, S.8
Hoyo, C.9
Fuemmeler, B.F.10
-
38
-
-
58349119112
-
Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease
-
Cunningham, C., Campion, S., Lunnon, K., Murray, C.L., Woods, J.F., Deacon, R.M., Rawlins, J.N., Perry, V.H., Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease. Biol Psychiatry 65 (2009), 304–312.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 304-312
-
-
Cunningham, C.1
Campion, S.2
Lunnon, K.3
Murray, C.L.4
Woods, J.F.5
Deacon, R.M.6
Rawlins, J.N.7
Perry, V.H.8
-
39
-
-
84888794751
-
Inflammation and the two-hit hypothesis of schizophrenia
-
Feigenson, K.A., Kusnecov, A.W., Silverstein, S.M., Inflammation and the two-hit hypothesis of schizophrenia. Neurosci Biobehav Rev 38 (2014), 72–93.
-
(2014)
Neurosci Biobehav Rev
, vol.38
, pp. 72-93
-
-
Feigenson, K.A.1
Kusnecov, A.W.2
Silverstein, S.M.3
-
40
-
-
85029933030
-
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
-
Fuger, P., Hefendehl, J.K., Veeraraghavalu, K., Wendeln, A.C., Schlosser, C., Obermuller, U., Wegenast-Braun, B.M., Neher, J.J., Martus, P., Kohsaka, S., et al. Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging. Nat Neurosci, 2017.
-
(2017)
Nat Neurosci
-
-
Fuger, P.1
Hefendehl, J.K.2
Veeraraghavalu, K.3
Wendeln, A.C.4
Schlosser, C.5
Obermuller, U.6
Wegenast-Braun, B.M.7
Neher, J.J.8
Martus, P.9
Kohsaka, S.10
-
41
-
-
85025596546
-
The lifespan and turnover of microglia in the human brain
-
Reu, P., Khosravi, A., Bernard, S., Mold, J.E., Salehpour, M., Alkass, K., Perl, S., Tisdale, J., Possnert, G., Druid, H., et al. The lifespan and turnover of microglia in the human brain. Cell Rep 20 (2017), 779–784.
-
(2017)
Cell Rep
, vol.20
, pp. 779-784
-
-
Reu, P.1
Khosravi, A.2
Bernard, S.3
Mold, J.E.4
Salehpour, M.5
Alkass, K.6
Perl, S.7
Tisdale, J.8
Possnert, G.9
Druid, H.10
-
42
-
-
33244494436
-
A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats
-
Bilbo, S.D., Rudy, J.W., Watkins, L.R., Maier, S.F., A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats. Behav Brain Res 169 (2006), 39–47.
-
(2006)
Behav Brain Res
, vol.169
, pp. 39-47
-
-
Bilbo, S.D.1
Rudy, J.W.2
Watkins, L.R.3
Maier, S.F.4
-
43
-
-
84971596960
-
Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets
-
Early-life viral infection in pigs leads to upregulation of microglial 'sensome’ genes in the hippocampus later in life, accompanied by increases in microglial phagocytic activity in vitro.
-
Ji, P., Schachtschneider, K.M., Schook, L.B., Walker, F.R., Johnson, R.W., Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets. Brain Behav Immun 54 (2016), 243–251 Early-life viral infection in pigs leads to upregulation of microglial 'sensome’ genes in the hippocampus later in life, accompanied by increases in microglial phagocytic activity in vitro.
-
(2016)
Brain Behav Immun
, vol.54
, pp. 243-251
-
-
Ji, P.1
Schachtschneider, K.M.2
Schook, L.B.3
Walker, F.R.4
Johnson, R.W.5
-
44
-
-
77950947668
-
Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain
-
Bland, S.T., Beckley, J.T., Young, S., Tsang, V., Watkins, L.R., Maier, S.F., Bilbo, S.D., Enduring consequences of early-life infection on glial and neural cell genesis within cognitive regions of the brain. Brain Behav Immun 24 (2010), 329–338.
-
(2010)
Brain Behav Immun
, vol.24
, pp. 329-338
-
-
Bland, S.T.1
Beckley, J.T.2
Young, S.3
Tsang, V.4
Watkins, L.R.5
Maier, S.F.6
Bilbo, S.D.7
-
45
-
-
84947916984
-
Late prenatal immune activation causes hippocampal deficits in the absence of persistent inflammation across aging
-
Giovanoli, S., Notter, T., Richetto, J., Labouesse, M.A., Vuillermot, S., Riva, M.A., Meyer, U., Late prenatal immune activation causes hippocampal deficits in the absence of persistent inflammation across aging. J Neuroinflammation, 12, 2015, 221.
-
(2015)
J Neuroinflammation
, vol.12
, pp. 221
-
-
Giovanoli, S.1
Notter, T.2
Richetto, J.3
Labouesse, M.A.4
Vuillermot, S.5
Riva, M.A.6
Meyer, U.7
-
46
-
-
84994501931
-
Maternal viral infection during pregnancy elicits anti-social behavior in neonatal piglet offspring independent of postnatal microglial cell activation
-
Antonson, A.M., Radlowski, E.C., Lawson, M.A., Rytych, J.L., Johnson, R.W., Maternal viral infection during pregnancy elicits anti-social behavior in neonatal piglet offspring independent of postnatal microglial cell activation. Brain Behav Immun 59 (2017), 300–312.
-
(2017)
Brain Behav Immun
, vol.59
, pp. 300-312
-
-
Antonson, A.M.1
Radlowski, E.C.2
Lawson, M.A.3
Rytych, J.L.4
Johnson, R.W.5
-
47
-
-
84976883162
-
Microglia development follows a stepwise program to regulate brain homeostasis
-
Authors identified three stages of microglia development, which are characterized by distinct gene expression and linked with chromatin changes, occurring in sync with the developing brain. Furthermore, they demonstrate that the proper development of microglia is affected by the microbiome. Maternal immune activation resulted in a transcriptional shift of ‘pre-microglia’ toward a more advanced developmental stage.
-
Matcovitch-Natan, O., Winter, D.R., Giladi, A., Vargas Aguilar, S., Spinrad, A., Sarrazin, S., Ben-Yehuda, H., David, E., Zelada Gonzalez, F., Perrin, P., et al. Microglia development follows a stepwise program to regulate brain homeostasis. Science, 353, 2016, aad8670 Authors identified three stages of microglia development, which are characterized by distinct gene expression and linked with chromatin changes, occurring in sync with the developing brain. Furthermore, they demonstrate that the proper development of microglia is affected by the microbiome. Maternal immune activation resulted in a transcriptional shift of ‘pre-microglia’ toward a more advanced developmental stage.
-
(2016)
Science
, vol.353
, pp. aad8670
-
-
Matcovitch-Natan, O.1
Winter, D.R.2
Giladi, A.3
Vargas Aguilar, S.4
Spinrad, A.5
Sarrazin, S.6
Ben-Yehuda, H.7
David, E.8
Zelada Gonzalez, F.9
Perrin, P.10
-
48
-
-
85020135902
-
Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity
-
The authors describe sex differences in microglial developmental trajectory in mice in which female microglia mature more quickly than male microglia during normal development. Further, microglial transcriptional responses to LPS differed between male and female mice, which were strongly correlated to changes in morphology. Finally, using these transcriptome data from purified mouse microglia, authors show accelerated microglial development in human brain disease such as autism and Alzheimer's disease.
-
Hanamsagar, R., Alter, M.D., Block, C.S., Sullivan, H., Bolton, J.L., Bilbo, S.D., Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity. Glia 65 (2017), 1504–1520 The authors describe sex differences in microglial developmental trajectory in mice in which female microglia mature more quickly than male microglia during normal development. Further, microglial transcriptional responses to LPS differed between male and female mice, which were strongly correlated to changes in morphology. Finally, using these transcriptome data from purified mouse microglia, authors show accelerated microglial development in human brain disease such as autism and Alzheimer's disease.
-
(2017)
Glia
, vol.65
, pp. 1504-1520
-
-
Hanamsagar, R.1
Alter, M.D.2
Block, C.S.3
Sullivan, H.4
Bolton, J.L.5
Bilbo, S.D.6
-
49
-
-
84948568111
-
Sex differences in neurodevelopmental and neurodegenerative disorders: focus on microglial function and neuroinflammation during development
-
Hanamsagar, R., Bilbo, S.D., Sex differences in neurodevelopmental and neurodegenerative disorders: focus on microglial function and neuroinflammation during development. J Steroid Biochem Mol Biol 160 (2016), 127–133.
-
(2016)
J Steroid Biochem Mol Biol
, vol.160
, pp. 127-133
-
-
Hanamsagar, R.1
Bilbo, S.D.2
-
50
-
-
84857917135
-
Sex differences in microglial colonization of the developing rat brain
-
Schwarz, J.M., Sholar, P.W., Bilbo, S.D., Sex differences in microglial colonization of the developing rat brain. J Neurochem 120 (2012), 948–963.
-
(2012)
J Neurochem
, vol.120
, pp. 948-963
-
-
Schwarz, J.M.1
Sholar, P.W.2
Bilbo, S.D.3
-
51
-
-
84994642931
-
Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products
-
Carter, C.J., Blizard, R.A., Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products. Neurochem Int, 2016.
-
(2016)
Neurochem Int
-
-
Carter, C.J.1
Blizard, R.A.2
-
52
-
-
85006757073
-
Rapid and sensitive detection of bisphenol a from serum matrix
-
Lin, X., Cheng, C., Terry, P., Chen, J., Cui, H., Wu, J., Rapid and sensitive detection of bisphenol a from serum matrix. Biosens Bioelectron 91 (2016), 104–109.
-
(2016)
Biosens Bioelectron
, vol.91
, pp. 104-109
-
-
Lin, X.1
Cheng, C.2
Terry, P.3
Chen, J.4
Cui, H.5
Wu, J.6
-
53
-
-
48749119557
-
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier
-
Hartz, A.M., Bauer, B., Block, M.L., Hong, J.S., Miller, D.S., Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier. FASEB J 22 (2008), 2723–2733.
-
(2008)
FASEB J
, vol.22
, pp. 2723-2733
-
-
Hartz, A.M.1
Bauer, B.2
Block, M.L.3
Hong, J.S.4
Miller, D.S.5
-
54
-
-
79961033108
-
Diesel exhaust activates and primes microglia: Air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity
-
Levesque, S., Taetzsch, T., Lull, M.E., Kodavanti, U., Stadler, K., Wagner, A., Johnson, J.A., Duke, L., Kodavanti, P., Surace, M.J., Diesel exhaust activates and primes microglia: Air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity. Environ Health Perspect, 119, 2011, 1149.
-
(2011)
Environ Health Perspect
, vol.119
, pp. 1149
-
-
Levesque, S.1
Taetzsch, T.2
Lull, M.E.3
Kodavanti, U.4
Stadler, K.5
Wagner, A.6
Johnson, J.A.7
Duke, L.8
Kodavanti, P.9
Surace, M.J.10
-
55
-
-
85031722400
-
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
-
Collaborators GBDRF, Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390 (2017), 1345–1422.
-
(2017)
Lancet
, vol.390
, pp. 1345-1422
-
-
Collaborators GBDRF1
-
56
-
-
84953392157
-
Ambient air pollution exposure estimation for the global burden of disease 2013
-
Brauer, M., Freedman, G., Frostad, J., van Donkelaar, A., Martin, R.V., Dentener, F., van Dingenen, R., Estep, K., Amini, H., Apte, J.S., et al. Ambient air pollution exposure estimation for the global burden of disease 2013. Environ Sci Technol 50 (2016), 79–88.
-
(2016)
Environ Sci Technol
, vol.50
, pp. 79-88
-
-
Brauer, M.1
Freedman, G.2
Frostad, J.3
van Donkelaar, A.4
Martin, R.V.5
Dentener, F.6
van Dingenen, R.7
Estep, K.8
Amini, H.9
Apte, J.S.10
-
57
-
-
6344244680
-
Estimated risk for altered fetal growth resulting from exposure to fine particles during pregnancy: an epidemiologic prospective cohort study in Poland
-
Jedrychowski, W., Bendkowska, I., Flak, E., Penar, A., Jacek, R., Kaim, I., Spengler, J.D., Camann, D., Perera, F.P., Estimated risk for altered fetal growth resulting from exposure to fine particles during pregnancy: an epidemiologic prospective cohort study in Poland. Environ Health Perspect 112 (2004), 1398–1402.
-
(2004)
Environ Health Perspect
, vol.112
, pp. 1398-1402
-
-
Jedrychowski, W.1
Bendkowska, I.2
Flak, E.3
Penar, A.4
Jacek, R.5
Kaim, I.6
Spengler, J.D.7
Camann, D.8
Perera, F.P.9
-
58
-
-
84908395017
-
Environmental toxicants and autism spectrum disorders: a systematic review
-
Rossignol, D.A., Genuis, S.J., Frye, R.E., Environmental toxicants and autism spectrum disorders: a systematic review. Transl Psychiatry, 4, 2014, e360.
-
(2014)
Transl Psychiatry
, vol.4
, pp. e360
-
-
Rossignol, D.A.1
Genuis, S.J.2
Frye, R.E.3
-
59
-
-
84880980761
-
Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses’ Health Study II participants
-
Roberts, A.L., Lyall, K., Hart, J.E., Laden, F., Just, A.C., Bobb, J.F., Koenen, K.C., Ascherio, A., Weisskopf, M.G., Perinatal air pollutant exposures and autism spectrum disorder in the children of Nurses’ Health Study II participants. Environ Health Perspect 121 (2013), 978–984.
-
(2013)
Environ Health Perspect
, vol.121
, pp. 978-984
-
-
Roberts, A.L.1
Lyall, K.2
Hart, J.E.3
Laden, F.4
Just, A.C.5
Bobb, J.F.6
Koenen, K.C.7
Ascherio, A.8
Weisskopf, M.G.9
-
60
-
-
85016301332
-
Neurotoxicity of traffic-related air pollution
-
Costa, L.G., Cole, T.B., Coburn, J., Chang, Y.C., Dao, K., Roque, P.J., Neurotoxicity of traffic-related air pollution. Neurotoxicology, 2015.
-
(2015)
Neurotoxicology
-
-
Costa, L.G.1
Cole, T.B.2
Coburn, J.3
Chang, Y.C.4
Dao, K.5
Roque, P.J.6
-
61
-
-
84867230254
-
The outdoor air pollution and brain health workshop
-
Block, M.L., Elder, A., Auten, R.L., Bilbo, S.D., Chen, H., Chen, J.C., Cory-Slechta, D.A., Costa, D., Diaz-Sanchez, D., Dorman, D.C., et al. The outdoor air pollution and brain health workshop. Neurotoxicology 33 (2012), 972–984.
-
(2012)
Neurotoxicology
, vol.33
, pp. 972-984
-
-
Block, M.L.1
Elder, A.2
Auten, R.L.3
Bilbo, S.D.4
Chen, H.5
Chen, J.C.6
Cory-Slechta, D.A.7
Costa, D.8
Diaz-Sanchez, D.9
Dorman, D.C.10
-
62
-
-
84862777928
-
Diesel exhaust particles and airway inflammation
-
Ghio, A.J., Smith, C.B., Madden, M.C., Diesel exhaust particles and airway inflammation. Curr Opin Pulm Med 18 (2012), 144–150.
-
(2012)
Curr Opin Pulm Med
, vol.18
, pp. 144-150
-
-
Ghio, A.J.1
Smith, C.B.2
Madden, M.C.3
-
63
-
-
85020110865
-
Gestational exposure to air pollution alters cortical volume, microglial morphology, and microglia–neuron interactions in a sex-specific manner
-
Bolton, J.L., Marinero, S., Hassanzadeh, T., Natesan, D., Le, D., Belliveau, C., Mason, S.N., Auten, R.L., Bilbo, S.D., Gestational exposure to air pollution alters cortical volume, microglial morphology, and microglia–neuron interactions in a sex-specific manner. Front Synaptic Neurosci, 9, 2017, 10.
-
(2017)
Front Synaptic Neurosci
, vol.9
, pp. 10
-
-
Bolton, J.L.1
Marinero, S.2
Hassanzadeh, T.3
Natesan, D.4
Le, D.5
Belliveau, C.6
Mason, S.N.7
Auten, R.L.8
Bilbo, S.D.9
-
64
-
-
85017145947
-
Neuropathological consequences of gestational exposure to concentrated ambient fine and ultrafine particles in the mouse
-
Klocke, C., Allen, J.L., Sobolewski, M., Mayer-Proschel, M., Blum, J.L., Lauterstein, D., Zelikoff, J.T., Cory-Slechta, D.A., Neuropathological consequences of gestational exposure to concentrated ambient fine and ultrafine particles in the mouse. Toxicol Sci 156 (2017), 492–508.
-
(2017)
Toxicol Sci
, vol.156
, pp. 492-508
-
-
Klocke, C.1
Allen, J.L.2
Sobolewski, M.3
Mayer-Proschel, M.4
Blum, J.L.5
Lauterstein, D.6
Zelikoff, J.T.7
Cory-Slechta, D.A.8
-
65
-
-
84953439557
-
Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders
-
Allen, J.L., Oberdorster, G., Morris-Schaffer, K., Wong, C., Klocke, C., Sobolewski, M., Conrad, K., Mayer-Proschel, M., Cory-Slechta, D.A., Developmental neurotoxicity of inhaled ambient ultrafine particle air pollution: parallels with neuropathological and behavioral features of autism and other neurodevelopmental disorders. Neurotoxicology 59 (2017), 140–154.
-
(2017)
Neurotoxicology
, vol.59
, pp. 140-154
-
-
Allen, J.L.1
Oberdorster, G.2
Morris-Schaffer, K.3
Wong, C.4
Klocke, C.5
Sobolewski, M.6
Conrad, K.7
Mayer-Proschel, M.8
Cory-Slechta, D.A.9
-
66
-
-
85017464891
-
Altered white matter integrity in adults with autism spectrum disorder and an IQ >100: a diffusion tensor imaging study
-
Nickel, K., Tebartz van Elst, L., Perlov, E., Endres, D., Muller, G.T., Riedel, A., Fangmeier, T., Maier, S., Altered white matter integrity in adults with autism spectrum disorder and an IQ >100: a diffusion tensor imaging study. Acta Psychiatr Scand 135 (2017), 573–583.
-
(2017)
Acta Psychiatr Scand
, vol.135
, pp. 573-583
-
-
Nickel, K.1
Tebartz van Elst, L.2
Perlov, E.3
Endres, D.4
Muller, G.T.5
Riedel, A.6
Fangmeier, T.7
Maier, S.8
-
67
-
-
84939540039
-
Excitatory/inhibitory balance and circuit homeostasis in autism spectrum disorders
-
Nelson, S.B., Valakh, V., Excitatory/inhibitory balance and circuit homeostasis in autism spectrum disorders. Neuron 87 (2015), 684–698.
-
(2015)
Neuron
, vol.87
, pp. 684-698
-
-
Nelson, S.B.1
Valakh, V.2
-
68
-
-
84883284551
-
Maternal stress and effects of prenatal air pollution on offspring mental health outcomes in mice
-
Bolton, J.L., Huff, N.C., Smith, S.H., Mason, S.N., Foster, W.M., Auten, R.L., Bilbo, S.D., Maternal stress and effects of prenatal air pollution on offspring mental health outcomes in mice. Environ Health Perspect 121 (2013), 1075–1082.
-
(2013)
Environ Health Perspect
, vol.121
, pp. 1075-1082
-
-
Bolton, J.L.1
Huff, N.C.2
Smith, S.H.3
Mason, S.N.4
Foster, W.M.5
Auten, R.L.6
Bilbo, S.D.7
-
69
-
-
13844275495
-
The lasting impact of childhood health and circumstance
-
Case, A., Fertig, A., Paxson, C., The lasting impact of childhood health and circumstance. J Health Econ 24 (2005), 365–389.
-
(2005)
J Health Econ
, vol.24
, pp. 365-389
-
-
Case, A.1
Fertig, A.2
Paxson, C.3
-
70
-
-
77955951477
-
Socioeconomic status and the brain: mechanistic insights from human and animal research
-
Hackman, D.A., Farah, M.J., Meaney, M.J., Socioeconomic status and the brain: mechanistic insights from human and animal research. Nat Rev Neurosci 11 (2010), 651–659.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 651-659
-
-
Hackman, D.A.1
Farah, M.J.2
Meaney, M.J.3
-
71
-
-
68149119286
-
Parental stress increases the effect of traffic-related air pollution on childhood asthma incidence
-
Shankardass, K., McConnell, R., Jerrett, M., Milam, J., Richardson, J., Berhane, K., Parental stress increases the effect of traffic-related air pollution on childhood asthma incidence. Proc Natl Acad Sci U S A 106 (2009), 12406–12411.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12406-12411
-
-
Shankardass, K.1
McConnell, R.2
Jerrett, M.3
Milam, J.4
Richardson, J.5
Berhane, K.6
-
72
-
-
84859887139
-
Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice
-
Diz-Chaves, Y., Pernia, O., Carrero, P., Garcia-Segura, L.M., Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice. J Neuroinflammation, 9, 2012, 71.
-
(2012)
J Neuroinflammation
, vol.9
, pp. 71
-
-
Diz-Chaves, Y.1
Pernia, O.2
Carrero, P.3
Garcia-Segura, L.M.4
-
73
-
-
84926377243
-
Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment
-
Maternal stress, in the form of sleep deprivation in pregnant rats, results in increased microglia number and activation markers, decreased hippocampal neurogenesis and impaired hippocampus-dependent spatial learning and memory in offspring. These effects can be reversed by prepubertal administration of minocycline in the offspring.
-
Zhao, Q., Xie, X., Fan, Y., Zhang, J., Jiang, W., Wu, X., Yan, S., Chen, Y., Peng, C., You, Z., Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment. Sci Rep, 5, 2015, 9513 Maternal stress, in the form of sleep deprivation in pregnant rats, results in increased microglia number and activation markers, decreased hippocampal neurogenesis and impaired hippocampus-dependent spatial learning and memory in offspring. These effects can be reversed by prepubertal administration of minocycline in the offspring.
-
(2015)
Sci Rep
, vol.5
, pp. 9513
-
-
Zhao, Q.1
Xie, X.2
Fan, Y.3
Zhang, J.4
Jiang, W.5
Wu, X.6
Yan, S.7
Chen, Y.8
Peng, C.9
You, Z.10
-
74
-
-
84957607802
-
Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness
-
This is a systematic review of effects of stress on microglia using pre-defined search criteria on PubMed and EMBASE. Authors found consistent evidence that a range of psychosocial stressors lead to elevated microglial activity in the hippocampus and other brain regions. These effects were seen with early-life/prenatal stress, as well as stressors in adulthood.
-
Calcia, M.A., Bonsall, D.R., Bloomfield, P.S., Selvaraj, S., Barichello, T., Howes, O.D., Stress and neuroinflammation: a systematic review of the effects of stress on microglia and the implications for mental illness. Psychopharmacology (Berl) 233 (2016), 1637–1650 This is a systematic review of effects of stress on microglia using pre-defined search criteria on PubMed and EMBASE. Authors found consistent evidence that a range of psychosocial stressors lead to elevated microglial activity in the hippocampus and other brain regions. These effects were seen with early-life/prenatal stress, as well as stressors in adulthood.
-
(2016)
Psychopharmacology (Berl)
, vol.233
, pp. 1637-1650
-
-
Calcia, M.A.1
Bonsall, D.R.2
Bloomfield, P.S.3
Selvaraj, S.4
Barichello, T.5
Howes, O.D.6
-
75
-
-
53249109683
-
A novel mouse model for acute and long-lasting consequences of early life stress
-
Rice, C.J., Sandman, C.A., Lenjavi, M.R., Baram, T.Z., A novel mouse model for acute and long-lasting consequences of early life stress. Endocrinology 149 (2008), 4892–4900.
-
(2008)
Endocrinology
, vol.149
, pp. 4892-4900
-
-
Rice, C.J.1
Sandman, C.A.2
Lenjavi, M.R.3
Baram, T.Z.4
-
76
-
-
84896725191
-
Prenatal air pollution exposure induces sexually dimorphic fetal programming of metabolic and neuroinflammatory outcomes in adult offspring
-
Bolton, J.L., Auten, R.L., Bilbo, S.D., Prenatal air pollution exposure induces sexually dimorphic fetal programming of metabolic and neuroinflammatory outcomes in adult offspring. Brain Behav Immun 37 (2014), 30–44.
-
(2014)
Brain Behav Immun
, vol.37
, pp. 30-44
-
-
Bolton, J.L.1
Auten, R.L.2
Bilbo, S.D.3
-
77
-
-
84868296575
-
Prenatal air pollution exposure induces neuroinflammation and predisposes offspring to weight gain in adulthood in a sex-specific manner
-
Bolton, J.L., Smith, S.H., Huff, N.C., Gilmour, M.I., Foster, W.M., Auten, R.L., Bilbo, S.D., Prenatal air pollution exposure induces neuroinflammation and predisposes offspring to weight gain in adulthood in a sex-specific manner. FASEB J 26 (2012), 4743–4754.
-
(2012)
FASEB J
, vol.26
, pp. 4743-4754
-
-
Bolton, J.L.1
Smith, S.H.2
Huff, N.C.3
Gilmour, M.I.4
Foster, W.M.5
Auten, R.L.6
Bilbo, S.D.7
-
78
-
-
84992170640
-
Early life stress perturbs the maturation of microglia in the developing hippocampus
-
In this study, authors used brief daily separation (BDS) as a model for early-life stress. In BDS offspring, microglial cell density decreases, and inflammatory and cell migration gene expression increases. Microglia harvested from the hippocampus of 28-day old BDS mice showed an increase in phagocytic activity.
-
Delpech, J.C., Wei, L., Hao, J., Yu, X., Madore, C., Butovsky, O., Kaffman, A., Early life stress perturbs the maturation of microglia in the developing hippocampus. Brain Behav Immun 57 (2016), 79–93 In this study, authors used brief daily separation (BDS) as a model for early-life stress. In BDS offspring, microglial cell density decreases, and inflammatory and cell migration gene expression increases. Microglia harvested from the hippocampus of 28-day old BDS mice showed an increase in phagocytic activity.
-
(2016)
Brain Behav Immun
, vol.57
, pp. 79-93
-
-
Delpech, J.C.1
Wei, L.2
Hao, J.3
Yu, X.4
Madore, C.5
Butovsky, O.6
Kaffman, A.7
-
79
-
-
84973402694
-
Fractalkine attenuates microglial cell activation induced by prenatal stress
-
Slusarczyk, J., Trojan, E., Glombik, K., Chamera, K., Roman, A., Budziszewska, B., Basta-Kaim, A., Fractalkine attenuates microglial cell activation induced by prenatal stress. Neural Plast, 2016, 2016, 7258201.
-
(2016)
Neural Plast
, vol.2016
, pp. 7258201
-
-
Slusarczyk, J.1
Trojan, E.2
Glombik, K.3
Chamera, K.4
Roman, A.5
Budziszewska, B.6
Basta-Kaim, A.7
-
80
-
-
84937126408
-
Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection
-
Williamson, L.L., McKenney, E.A., Holzknecht, Z.E., Belliveau, C., Rawls, J.F., Poulton, S., Parker, W., Bilbo, S.D., Got worms? Perinatal exposure to helminths prevents persistent immune sensitization and cognitive dysfunction induced by early-life infection. Brain Behav Immun 51 (2016), 14–28.
-
(2016)
Brain Behav Immun
, vol.51
, pp. 14-28
-
-
Williamson, L.L.1
McKenney, E.A.2
Holzknecht, Z.E.3
Belliveau, C.4
Rawls, J.F.5
Poulton, S.6
Parker, W.7
Bilbo, S.D.8
-
81
-
-
20444416345
-
Suppression of glial activation is involved in the protection of IL-10 on maternal E. coli induced neonatal white matter injury
-
Pang, Y., Rodts-Palenik, S., Cai, Z., Bennett, W.A., Rhodes, P.G., Suppression of glial activation is involved in the protection of IL-10 on maternal E. coli induced neonatal white matter injury. Brain Res Dev Brain Res 157 (2005), 141–149.
-
(2005)
Brain Res Dev Brain Res
, vol.157
, pp. 141-149
-
-
Pang, Y.1
Rodts-Palenik, S.2
Cai, Z.3
Bennett, W.A.4
Rhodes, P.G.5
-
82
-
-
84856591762
-
Maternal infection during late pregnancy increases anxiety- and depression-like behaviors with increasing age in male offspring
-
Enayati, M., Solati, J., Hosseini, M.H., Shahi, H.R., Saki, G., Salari, A.A., Maternal infection during late pregnancy increases anxiety- and depression-like behaviors with increasing age in male offspring. Brain Res Bull 87 (2012), 295–302.
-
(2012)
Brain Res Bull
, vol.87
, pp. 295-302
-
-
Enayati, M.1
Solati, J.2
Hosseini, M.H.3
Shahi, H.R.4
Saki, G.5
Salari, A.A.6
-
83
-
-
85019321120
-
Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring
-
Fernandez de Cossio, L., Guzman, A., van der Veldt, S., Luheshi, G.N., Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring. Brain Behav Immun, 2016.
-
(2016)
Brain Behav Immun
-
-
Fernandez de Cossio, L.1
Guzman, A.2
van der Veldt, S.3
Luheshi, G.N.4
-
84
-
-
85026192650
-
Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood
-
Schaafsma, W., Basterra, L.B., Jacobs, S., Brouwer, N., Meerlo, P., Schaafsma, A., Boddeke, E., Eggen, B.J.L., Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood. Neurobiol Dis 106 (2017), 291–300.
-
(2017)
Neurobiol Dis
, vol.106
, pp. 291-300
-
-
Schaafsma, W.1
Basterra, L.B.2
Jacobs, S.3
Brouwer, N.4
Meerlo, P.5
Schaafsma, A.6
Boddeke, E.7
Eggen, B.J.L.8
-
85
-
-
50249137611
-
Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function
-
Roumier, A., Pascual, O., Bechade, C., Wakselman, S., Poncer, J.C., Real, E., Triller, A., Bessis, A., Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function. PLoS ONE, 3, 2008, e2595.
-
(2008)
PLoS ONE
, vol.3
, pp. e2595
-
-
Roumier, A.1
Pascual, O.2
Bechade, C.3
Wakselman, S.4
Poncer, J.C.5
Real, E.6
Triller, A.7
Bessis, A.8
-
86
-
-
84859887139
-
Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice
-
Diz-Chaves, Y., Pernía, O., Carrero, P., Garcia-Segura, L., Prenatal stress causes alterations in the morphology of microglia and the inflammatory response of the hippocampus of adult female mice. J Neuroinflammation, 9, 2012, 71.
-
(2012)
J Neuroinflammation
, vol.9
, pp. 71
-
-
Diz-Chaves, Y.1
Pernía, O.2
Carrero, P.3
Garcia-Segura, L.4
-
87
-
-
84926377243
-
Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment
-
Zhao, Q., Xie, X., Fan, Y., Zhang, J., Jiang, W., Wu, X., Yan, S., Chen, Y., Peng, C., You, Z., Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment. Sci Rep, 5, 2015, 9513.
-
(2015)
Sci Rep
, vol.5
, pp. 9513
-
-
Zhao, Q.1
Xie, X.2
Fan, Y.3
Zhang, J.4
Jiang, W.5
Wu, X.6
Yan, S.7
Chen, Y.8
Peng, C.9
You, Z.10
-
88
-
-
84963705460
-
Preventive effects of minocycline in a neurodevelopmental two-hit model with relevance to schizophrenia
-
Giovanoli, S., Engler, H., Engler, A., Richetto, J., Feldon, J., Riva, M.A., Schedlowski, M., Meyer, U., Preventive effects of minocycline in a neurodevelopmental two-hit model with relevance to schizophrenia. Transl Psychiatry, 6, 2016, e772.
-
(2016)
Transl Psychiatry
, vol.6
, pp. e772
-
-
Giovanoli, S.1
Engler, H.2
Engler, A.3
Richetto, J.4
Feldon, J.5
Riva, M.A.6
Schedlowski, M.7
Meyer, U.8
-
89
-
-
41349099144
-
Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood
-
Bilbo, S.D., Barrientos, R.M., Eads, A.S., Northcutt, A., Watkins, L.R., Rudy, J.W., Maier, S.F., Early-life infection leads to altered BDNF and IL-1beta mRNA expression in rat hippocampus following learning in adulthood. Brain Behav Immun 22 (2008), 451–455.
-
(2008)
Brain Behav Immun
, vol.22
, pp. 451-455
-
-
Bilbo, S.D.1
Barrientos, R.M.2
Eads, A.S.3
Northcutt, A.4
Watkins, L.R.5
Rudy, J.W.6
Maier, S.F.7
-
90
-
-
84885121954
-
Neonatal E. coli infection causes neuro-behavioral deficits associated with hypomyelination and neuronal sequestration of iron
-
Lieblein-Boff, J.C., McKim, D.B., Shea, D.T., Wei, P., Deng, Z., Sawicki, C., Quan, N., Bilbo, S.D., Bailey, M.T., McTigue, D.M., et al. Neonatal E. coli infection causes neuro-behavioral deficits associated with hypomyelination and neuronal sequestration of iron. J Neurosci 33 (2013), 16334–16345.
-
(2013)
J Neurosci
, vol.33
, pp. 16334-16345
-
-
Lieblein-Boff, J.C.1
McKim, D.B.2
Shea, D.T.3
Wei, P.4
Deng, Z.5
Sawicki, C.6
Quan, N.7
Bilbo, S.D.8
Bailey, M.T.9
McTigue, D.M.10
-
91
-
-
84991463652
-
Early postnatal lipopolysaccharide exposure leads to enhanced neurogenesis and impaired communicative functions in rats
-
Pang, Y., Dai, X., Roller, A., Carter, K., Paul, I., Bhatt, A.J., Lin, R.C., Fan, L.W., Early postnatal lipopolysaccharide exposure leads to enhanced neurogenesis and impaired communicative functions in rats. PLOS ONE, 11, 2016, e0164403.
-
(2016)
PLOS ONE
, vol.11
, pp. e0164403
-
-
Pang, Y.1
Dai, X.2
Roller, A.3
Carter, K.4
Paul, I.5
Bhatt, A.J.6
Lin, R.C.7
Fan, L.W.8
-
92
-
-
84994083515
-
Neonatal lipopolysaccharide treatment alters hippocampal neuroinflammation, microglia morphology and anxiety-like behavior in rats selectively bred for an infantile trait
-
Claypoole, L.D., Zimmerberg, B., Williamson, L.L., Neonatal lipopolysaccharide treatment alters hippocampal neuroinflammation, microglia morphology and anxiety-like behavior in rats selectively bred for an infantile trait. Brain Behav Immun 59 (2017), 135–146.
-
(2017)
Brain Behav Immun
, vol.59
, pp. 135-146
-
-
Claypoole, L.D.1
Zimmerberg, B.2
Williamson, L.L.3
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