The Potency of Diarylamine Radical-Trapping Antioxidants as Inhibitors of Ferroptosis Underscores the Role of Autoxidation in the Mechanism of Cell Death

ACS Chemical Biology

Volumn 12, Issue 10, 2017, Pages 2538-2545

  Shah, Ron ^a   Margison, Kaitlyn ^a   Pratt, Derek A ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; ANTIOXIDANT; AROMATIC AMINE; DIPHENYLAMINE DERIVATIVE; DYE; GLUTATHIONE; HETEROCYCLIC COMPOUND; PETROLEUM; PHENOTHIAZINE DERIVATIVE; PHENOXAZINE DERIVATIVE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; RADICAL; 1,4-DIOXANE; AMINE; DIOXANE DERIVATIVE; GLUTATHIONE PEROXIDASE; LIPOSOME; PHOSPHOLIPID-HYDROPEROXIDE GLUTATHIONE PEROXIDASE;

ANIMAL CELL; ARTICLE; AUTOOXIDATION; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; FERROPTOSIS; GENE; GENE DELETION; GPX4 GENE; LIPID BILAYER; LIPID PEROXIDATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; AUTOPHAGY; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

AMINES; ANIMALS; ANTIOXIDANTS; APOPTOSIS; AUTOPHAGY; CELL LINE; CELL SURVIVAL; DIOXANES; FIBROBLASTS; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE PEROXIDASE; HUMANS; LIPID PEROXIDATION; LIPOSOMES; MICE; OXIDATION-REDUCTION;

EID: 85031940157     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.7b00730     Document Type: Article

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