STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum

Cell

Volumn 171, Issue 4, 2017, Pages 809-823.e13

  Moretti, Julien ^a   Roy, Soumit ^c,k   Bozec, Dominique ^c   Martinez, Jennifer ^d   Chapman, Jessica R ^e   Ueberheide, Beatrix ^e   Lamming, Dudley W ^f   Chen, Zhijian J ^g   Horng, Tiffany ^h   Yeretssian, Garabet ⁱ   Green, Douglas R ^j   Blander, J Magarian ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Weill Cornell Medical Center   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^g UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^h HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

ⁱ The Leona M and Harry B Helmsley Charitable Trust   (United States)

^j ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^k NONE   (United States)

more..

Author keywords

autophagy; c di AMP; cell autonomous innate immunity; ER stress; ER phagy; Gram positive bacteria; mTOR; STING; type I interferon; vita PAMP

Indexed keywords

ADENOSINE PHOSPHATE; CYCLIC DI ADENOSINE MONOPHOSPHATE; MAMMALIAN TARGET OF RAPAMYCIN; MEMBRANE PROTEIN; PATHOGEN ASSOCIATED MOLECULAR PATTERN; STING PROTEIN; UNCLASSIFIED DRUG; MPYS PROTEIN, MOUSE; MTOR PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELLULAR STRESS RESPONSE; ENDOPLASMIC RETICULUM STRESS; GRAM POSITIVE BACTERIUM; HOST RESISTANCE; IMMUNE RESPONSE; INTERFERON REPONSE; MICROBIAL VIABILITY; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ANIMAL; ENDOPLASMIC RETICULUM; FEMALE; GRAM POSITIVE INFECTION; IMMUNOLOGY; MALE; METABOLISM; MOUSE; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FEMALE; GRAM-POSITIVE BACTERIA; GRAM-POSITIVE BACTERIAL INFECTIONS; MALE; MEMBRANE PROTEINS; MICE; PATHOGEN-ASSOCIATED MOLECULAR PATTERN MOLECULES; PHAGOCYTES; TOR SERINE-THREONINE KINASES;

EID: 85031780991     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.09.034     Document Type: Article

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