Erratum: Protective Effects of Pretreatment with Quercetin Against Lipopolysaccharide-Induced Apoptosis and the Inhibition of Osteoblast Differentiation via the MAPK and Wnt/β-Catenin Pathways in MC3T3-E1 Cells (Cell Physiol Biochem (2017) 43 (1547–1561) DOI: 10.1159/000481978);Protective Effects of Pretreatment with Quercetin Against Lipopolysaccharide-Induced Apoptosis and the Inhibition of Osteoblast Differentiation via the MAPK and Wnt/β-Catenin Pathways in MC3T3-E1 Cells

Cellular Physiology and Biochemistry

Volumn 43, Issue 4, 2017, Pages 1547-1561

  Guo, Chun ^a,b   Yang, Rui Juan ^a   Jang, Ke ^c   Zhou, Xiao Ling ^a   Liu, Yu Zhen ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

^b HENAN UNIVERSITY   (China)

^c AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Differentiation; Lipopolysaccharide; MAPK; Osteoblast; Quercetin; Wnt ? catenin

Indexed keywords

7,8 DIHYDRO 2 [4 (TRIFLUOROMETHYL)PHENYL] 5H THIOPYRANO[4,3 D]PYRIMIDIN 4 OL; BETA CATENIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; QUERCETIN; WNT PROTEIN;

ALP GENE; ANIMAL CELL; APOPTOSIS; ARTICLE; BAX GENE; BCL 2 GENE; BCL XL GENE; BONE MINERALIZATION; CASPASE 3 GENE; CELL DIFFERENTIATION; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOCHROME C GENE; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE; GENE EXPRESSION; MC3T3-E1 CELL LINE; NONHUMAN; OCN GENE; OSTEOBLAST; OSX GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RUNX2 GENE; UPREGULATION; ANIMAL; BONE DEVELOPMENT; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; MAPK SIGNALING; METABOLISM; MOUSE; WNT SIGNALING;

ANIMALS; APOPTOSIS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; OSTEOBLASTS; OSTEOGENESIS; QUERCETIN; WNT SIGNALING PATHWAY;

EID: 85031765804     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.33594/000000609     Document Type: Erratum

References (45)

1. Nair SP, Meghji S, Wilson M, Reddi K, White P, Henderson B: Bacterially induced bone destruction: mechanisms and misconceptions. Infect Immun 1996; 64: 2371-2380.
2. Mörmann M, Thederan M, Nackchbandi I, Giese T, Wagner C, Hänsch GM: Lipopolysaccharides (LPS) induce the differentiation of human monocytes to osteoclasts in a tumour necrosis factor (TNF) alpha-dependent manner: a link between infection and pathological bone resorption. Mol Immunol 2008; 45: 3330-3337.
3. Itoh K, Udagawa N, Kobayashi K, Suda K, Li X, Takami M, Okahashi N, Nishihara T, Takahashi N: Lipopolysaccharide promotes the survival of osteoclasts via Toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages. J Immunol 2003; 170: 3688-3695.
4. Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T: Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells. Biochem Biophys Res Commun 2007; 360: 346-351.
5. Hou GQ, Guo C, Song GH, Fang N, Fan WJ, Chen XD, Yuan L, Wang ZQ: Lipopolysaccharide (LPS) promotes osteoclast differentiation and activation by enhancing the MAPK pathway and COX-2 expression in RAW264.7 cells. Int J Mol Med 2013; 32: 503-510.
6. Xing Q, Ye Q, Fan M, Zhou Y, Xu Q, Sandham A: Porphyromonas gingivalis lipopolysaccharide inhibits the osteoblastic differentiation of preosteoblasts by activating Notch1 signalling. J Cell Physiol 2010; 225: 106-114.
7. Ochi H, Hara Y, Tagawa M, Shinomiya K, Asou Y: The roles of TNFR1 in lipopolysaccharide-induced bone loss: dual effects of TNFR1 on bone metabolism via osteoclastogenesis and osteoblast survival. J Orthop Res 2010; 28: 657-663.
8. Kadono H, Kido J, Kataoka M, Yamauchi N, Nagata T: Inhibition of osteoblastic cell differentiation by lipopolysaccharide extracts from Porphyromonas gingivalis. Infect Immun 1999; 67: 2841-2846.
9. Guo C, Yuan L, Wang JG, Wang F, Yang XK, Zhang FH, Song JL, Ma XY, Cheng Q, Song GH: Lipopolysaccharide (LPS) induces the apoptosis and inhibits osteoblast differentiation through JNK pathway in MC3T3-E1 cells. Inflammation 2014; 37: 621-631.
10. Bandow K, Maeda A, Kakimoto K, Kusuyama J, Shamoto M, Ohnishi T, Matsuguchi T: Molecular mechanisms of the inhibitory effect of lipopolysaccharide (LPS) on osteoblast differentiation. Biochem Biophys Res Commun 2010; 402: 755-761.
11. Woo JT, Nakagawa H, Notoya M, Yonezawa T, Udagawa N, Lee IS, Ohnishi M, Hagiwara H, Nagai K: Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts. Biol Pharm Bull 2004; 27: 504-509.
12. Wattel A, Kamel S, Mentaverri R, Lorget F, Prouillet C, Petit JP, Fardelonne P, Brazier M: Potent inhibitory effect of naturally occurring flavonoids quercetin and kaempferol on in vitro osteoclastic bone resorption. Biochem Pharmacol 2003; 65: 35-42.
13. Siddiqui JA, Swarnkar G, Sharan K, Chakravarti B, Gautam AK, Rawat P, Kumar M, Gupta V, Manickavasagam L, Dwivedi AK, Maurya R, Chattopadhyay N: A naturally occurring rare analog of quercetin promotes peak bone mass achievement and exerts anabolic effect on osteoporotic bone. Osteoporos Int 2011; 22: 3013-3027.
14. Kittl M, Beyreis M, Tumurkhuu M, Fürst J, Helm K, Pitschmann A, Gaisberger M, Glasl S, Ritter M, Jakab M. Quercetin Stimulates Insulin Secretion and Reduces the Viability of Rat INS-1 Beta-Cells. Cell Physiol Biochem 2016; 39(1):278-293.
15. Guo C, Hou GQ, Li XD, Xia X, Liu DX, Huang DY, Du SX: Quercetin triggers apoptosis of lipopolysaccharide (LPS)-induced osteoclasts and inhibits bone resorption in RAW264.7 cells. Cell Physiol Biochem 2012; 30: 123-136.
16. Notoya M, Tsukamoto Y, Nishimura H, Woo JT, Nagai K, Lee IS, Hagiwara H: Quercetin, a flavonoid, inhibits the proliferation, differentiation, and mineralization of osteoblasts in vitro. Eur J Pharmacol 2004; 485: 89-96.
17. Son YO, Kook SH, Choi KC, Jang YS, Jeon YM, Kim JG, Lee KY, Kim J, Chung MS, Chung GH, Lee JC: Quercetin, a bioflavonoid, accelerates TNF-alpha-induced growth inhibition and apoptosis in MC3T3-E1 osteoblastic cells. Eur J Pharmacol 2006; 529: 24-32.
18. Nam TW, Yoo CI, Kim HT, Kwon CH, Park JY, Kim YK: The flavonoid quercetin induces apoptosis and inhibits migration through a MAPK-dependent mechanism in osteoblasts. J Bone Miner Metab 2008; 26: 551-560.
19. Prouillet C, Mazière JC, Mazière C, Wattel A, Brazier M, Kamel S: Stimulatory effect of naturally occurring flavonols quercetin and kaempferol on alkaline phosphatase activity in MG-63 human osteoblasts through ERK and estrogen receptor pathway. Biochem Pharmacol 2004; 67: 1307-1313.
20. Trivedi R, Kumar A, Gupta V, Kumar S, Nagar GK, Romero JR, Dwivedi AK, Chattopadhyay N: Effects of Egb 761 on bone mineral density, bone microstructure, and osteoblast function: Possible roles of quercetin and kaempferol. Mol Cell Endocrinol 2009; 302: 86-91.
21. Fatokun AA, Tome M, Smith RA, Darlington LG, Stone TW: Protection by the flavonoids quercetin and luteolin against peroxide-or menadione-induced oxidative stress in MC3T3-E1 osteoblast cells. Nat Prod Res 2015; 29: 1127-1132.
22. Wang XC, Zhao NJ, Guo C, Chen JT, Song JL, Gao L: Quercetin reversed lipopolysaccharide-induced inhibition of osteoblast differentiation through the mitogen-activated protein kinase pathway in MC3T3-E1 cells. Mol Med Rep 2014; 10: 3320-3326.
23. Matsuguchi T, Chiba N, Bandow K, Kakimoto K, Masuda A, Ohnishi T: JNK activity is essential for Atf4 expression and late-stage osteoblast differentiation. J Bone Miner Res 2009; 24: 398-410.
24. Guo C, Wang SL, Xu ST, Wang JG, Song GH: SP600125 reduces lipopolysaccharide-induced apoptosis and restores the early-stage differentiation of osteoblasts inhibited by LPS through the MAPK pathway in MC3T3-E1 cells. Int J Mol Med 2015; 35: 1427-1434.
25. Gutiérrez-Venegas G, Jiménez-Estrada M, Maldonado S: The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts. Int Immunopharmacol 2007; 7: 1199-1210.
26. Gao M, Wang H, Zhu L: Quercetin Assists Fluconazole to Inhibit Biofilm Formations of Fluconazole-Resistant Candida Albicans in In vitro and In vivo Antifungal Managements of Vulvovaginal Candidiasis. Cell Physiol Biochem 2016; 40: 727-742.
27. Gim H, Nam JH, Lee S, Shim JH, Kim HJ, Ha KT, Kim BJ: Quercetin Inhibits Pacemaker Potentials via Nitric Oxide/cGMP-Dependent Activation and TRPM7/ANO1 Channels in Cultured Interstitial Cells of Cajal from Mouse Small Intestine. Cell Physiol Biochem 2015; 35: 2422-2436.
28. Hoeppner LH, Secreto FJ, Westendorf JJ: Wnt signalling as a therapeutic target for bone diseases. Expert Opin Ther Targets 2009; 13: 485-496.
29. Long F: Building strong bones: molecular regulation of the osteoblast lineage. Nat Rev Mol Cell Biol 2012; 13: 27-38.
30. Baron R, Kneissel M: WNT signalling in bone homeostasis and disease: from human mutations to treatments. Nat Med 2013; 19: 179-192.
31. Kern B, Shen J, Starbuck M, Karsenty G: Cbfa1 contributes to the osteoblast-specific expression of type I collagen genes. J Biol Chem 2001; 276: 7101-7107.
32. Kim HK, Cho SG, Kim JH, Doan TK, Hu QS, Ulhaq R, Song EK, Yoon TR: Mevinolin enhances osteogenic genes (ALP, type I collagen and osteocalcin), CD44, CD47 and CD51 expression during osteogenic differentiation. Life Sci 2009; 84: 290-295.
33. Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B: The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 2002; 108: 17-29.
34. Fu H, Doll B, McNelis T, Hollinger JO: Osteoblast differentiation in vitro and in vivo promoted by Osterix. J Biomed Mater Res A 2007; 83: 770-778.
35. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH: Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 2001; 22: 153-183.
36. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-1331.
37. Fister S, Günthert AR, Aicher B, Paulini KW, Emons G, Gründker C: GnRH-II antagonists induce apoptosis in human endometrial, ovarian, and breast cancer cells via activation of stress-induced MAPKs p38 and JNK and proapoptotic protein Bax. Cancer Res 2009; 69: 6473-6481.
38. Park GB, Kim YS, Lee HK, Song H, Cho DH, Lee WJ, Hur DY: Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway. J Immunol 2010; 185: 7274-7284.
39. Lai SL, Chien AJ, Moon RT: Wnt/Fz signalling and the cytoskeleton: potential roles in tumorigenesis. Cell Res 2009; 19: 532-545.
40. Fuerer C, Nusse R, Ten Berge D: Wnt signalling in development and disease. EMBO Rep 2008; 9: 134-138.
41. Almeida M, Han L, Bellido T, Manolagas SC, Kousteni S: Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and-independent signalling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT. J Biol Chem 2005; 280: 41342-41351.
42. Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A: Axin, a negative regulator of the Wnt signalling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3 beta-dependent phosphorylation of beta-catenin. EMBO J 1998; 17: 1371-1384.
43. Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X: Control of beta-catenin phosphorylation/degradation by a dualkinase mechanism. Cell 2002; 108: 837-847.
44. Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W: Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996; 382: 638-642.
45. Novak A, Dedhar S: Signalling through beta-catenin and Lef/Tcf. Cell Mol Life Sci 1999; 56: 523-537.