Lipopolysaccharides (LPS) induce the differentiation of human monocytes to osteoclasts in a tumour necrosis factor (TNF) α-dependent manner: A link between infection and pathological bone resorption

Molecular Immunology

Volumn 45, Issue 12, 2008, Pages 3330-3337

  Mörmann, Maik ^a   Thederan, Mareike ^a   Nackchbandi, Inaam ^a,b   Giese, Thomas ^a   Wagner, Christof ^a,c   Hänsch, G Maria ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c UNFALLKRANKENHAUS BERLIN   (Germany)

Author keywords

Bone infection; Bone resorption; LPS; Monocytes; Osteoclasts; TNF ; U937

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CALCIUM PHOSPHATE; CATHEPSIN K; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL AGGREGATION; CELL DIFFERENTIATION; CELL STRAIN U937; CELL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFECTION; INFLAMMATION; MONOCYTE; MULTINUCLEAR CELL; OSTEOCLAST; OSTEOPOROSIS; PARACRINE SIGNALING; PRIORITY JOURNAL;

ANTIBODIES; ANTIGENS, CD14; BONE DISEASES, INFECTIOUS; BONE RESORPTION; CELL AGGREGATION; CELL DIFFERENTIATION; CELL SEPARATION; HUMANS; KINETICS; LIPOPOLYSACCHARIDES; MONOCYTES; OSTEOCLASTS; PHENOTYPE; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

BACTERIA (MICROORGANISMS);

EID: 44749086080     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.04.022     Document Type: Article

References (42)

1. Abu-Amer Y., Ross F.P., Edwards J., and Teitelbaum S.L. Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor. J. Clin. Invest. 10 (1997) 1557-1565
2. Asagiri M., and Takayanagi H. The molecular understanding of osteoclast differentiation. Bone 40 (2007) 251-264
3. Bendre M.S., Montague D.C., Peery T., Akel N.S., Gaddy D., and Suva L.J. Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. Bone 33 (2003) 28-37
4. Boyle W.J., Simonet W.S., and Lacey D.L. Osteoclast differentiation and activation. Nature 423 (2003) 337-342
5. Cannistra S.A., Rambaldi A., Spriggs D.R., Herrmann F., Kufe D., and Griffin J.D. Human granulocyte-macrophage colony-stimulating factor induces expression of the tumor necrosis factor gene by the U937 cell line and by normal human monocytes. J. Clin. Invest. 79 (1987) 1720-1728
6. Chung Y.H., Chang E.J., Kim S.J., Kim H.H., Kim H.M., Lee S.B., and Ko J.S. Lipopolysaccharide from Prevotella nigrescens stimulates osteoclastogenesis in cocultures of bone marrow mononuclear cells and primary osteoblasts. J. Periodontol. Res. 41 (2006) 288-296
7. Danks L., Sabokbar A., Gundle R., and Athanasou N.A. Synovial macrophage-osteoclast differentiation in inflammatory arthritis. Ann. Rheum. Dis. 61 (2002) 916-921
8. Doucet P., and Lowenstein M. Osteoclast activation by bacterial endotoxins during periodontal diseases. Med. Sci. 22 (2006) 614-620
9. Dumitrescu A.L., Abd-El-Aleem S., Morales-Aza B., and Donaldson L.F. A model of periodontitis in the rat: effect of lipopolysaccharide on bone resorption, osteoclast activity, and local peptidergic innervation. J. Clin. Periodontol. 3 (2004) 596-603
10. Ginsburg I. Role of lipoteichoic acid in infection and inflammation. Lancet Infect. Dis. 2 (2002) 171-179
11. Goppelt-Struebe M., Reiser C.O.A., Schneider N., and Grell M. Modulation of tumor necrosis factor (TNF) receptor expression during monocyte differentiation by glucocorticoids. Inflamm. Res. 45 (1996) 503-507
12. Graves D.T., Oskoui M., Volejnikova S., Naguib G., Cai S., Desta T., Kakouras A., and Jiang Y. Tumor necrosis factor modulates fibroblast apoptosis, PMN recruitment, and osteoclast formation in response to P. gingivalis infection. J. Dent. Res. 80 (2001) 1875-1879
13. Hass R., Bartels H., Topley N., Hadam M., Köhler L., Goppelt-Strübe M., and Resch K. TPA-induced differentiation and adhesion of U937 cells: changes in ultrastructure, cytoskeletal organization and expression of cell surface antigens. Eur. J. Cell. Biol. 48 (1989) 282-293
14. Henderson B., and Nair S.P. Hard labour: bacterial infection of the skeleton. Trends Microbiol. 11 (2003) 570-577
15. Honig A., Rieger L., Kapp M., Krockenberger M., Eck M., Dietl J., and Kämmerer U. Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study. BMC Cancer 199 (2006) 1-9
16. Husheem M., Nyman J.K.E., Vääräniemi J., Vaanaen H.K., and Hentunen T.A. Characterization of circulating human osteoclast progenitors: development of an in vitro resorption assay. Calcif. Tissue 76 (2005) 223-230
17. Islam S., Hassan F., Tumurkhuu G., Dagvadorj J., Koide N., Naiki Y., Mori I., Yoshida T., and Yokochi T. Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells. Biochem. Biophys. Res. Commun. 360 (2007) 346-351
18. Jiang Y., Mehta C.K., Hsu T.Y., and Alsulaimani F.F. Bacteria induce osteoclastogenesis via an osteoblast-independent pathway. Infect. Immun. 70 (2002) 3143-3148
19. Kudo O., Fujikawa Y., Itonaga I., Sabokbar A., Torisu T., and Athanasou N.A. Proinflammatory cytokine (TNFα/IL-1α) induction of human osteoclast formation. J. Pathol. 198 (2002) 220-227
20. Lally E.T., Kieba I.R., Sato A., Green C.L., Rosenbloom J., Korostoff J., Wang J.F., Shenker B.J., Ortlepp S., Robinson M.K., and Billings P.C. RTX toxins recognize a beta2 integrin on the surface of human target cells. J. Biol. Chem. 272 (1997) 30463-30469
21. Lee Z.H., and Kim H.H. Signal transduction by receptor activator of nuclear factor kappa B in osteoclasts. Biochem. Biophys. Res. Commun. 305 (2003) 211-214
22. Littlewood-Evans A.J., Bilbe G., Bowler W.B., Farley D., Wlodarski B., Kokubo T., Inaoka T., Sloane J., Evans D.B., and Gallagher J.A. The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma. Cancer Res. 57 (1997) 5386-5390
23. Matayoshi A., Brown C., DiPersio J.F., Haug J., Abu-Amer Y., Liapis H., Kuestner R., and Pacifici R. Human blood-mobilized hematopoietic precursors differentiate into osteoclasts in the absence of stromal cells. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 10785-10790
24. Nair S.P., Megghji S., Wilson M., Reddi K., White P., and Henderson B. Bacterially induced bone destruction: Mechanisms and Misconceptions. Infect. Immun. 64 (1996) 2371-2380
25. Nowack R., Schwalbe K., Flores-Suarez L.F., Yard B., and Van der Woude F.J. Upregulation of CD14 and CD18 on monocytes in vitro by antineutrophil cytoplasmic autoantibodies. J. Am. Soc. Nephrol. 11 (2000) 1639-1664
26. Orcel P., Feuga M., Bielakoff J., and De Vernejoul M.C. Local bone injections of LPS and M-CSF increase bone resorption by different pathways in vivo in rats. Am. J. Physiol. 264 (1993) 391-407
27. Plunkett T.A., and Rubens R.D. The biology and management of bone metastases. Critic. Rev. Oncol./Heamatol. 31 (1999) 89-96
28. Rivollier A., Mazzorana M., Tebib J., Piperno M., Aitsiselmi T., Rabourdin-Combe C., Jurdic P., and Servet-Delprat C. Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment. Blood 104 (2004) 4029-4037
29. Roodman G.D. Regulation of osteoclast differentiation. Ann. N. Y. Acad. Sci. 1068 (2006) 100-109
30. Russo C., and Polosa R. TNF-alpha as a promising therapeutic target in chronic asthma: a lesson from rheumatoid arthritis. Clin. Sci. (Lond.) 109 (2005) 135-142
31. Sakuma Y., Tanaka K., Suda M., Yasoda A., Natsui K., Tanaka I., Ushikubi F., Narumiya S., Segi E., Sugimoto Y., Ichikawa A., and Nakao K. Crucial involvement of the EP4 subtype of prostaglandin E receptor in osteoclast formation by proinflammatory cytokines and lipopolysaccharide. J. Bone Miner. Res. 15 (2000) 218-227
32. Scali J.J., Visentini S., Salomón J., Sevilla D., Ju Y.C., Morales E., Ugarte L., Tachdjian A., Pacheco G., and Veiga S. Rapid and deep control of inflammation in rheumatoid arthritis with infliximab and its correlation with acute-phase reactants. Ann. N. Y. Acad. Sci. 1110 (2007) 389-401
33. Suda K., Woo J.T., Takami M., Sexton P.M., and Nagai K. Lipopolysaccharide supports survival of preosteoclasts independent of TNF-alpha, IL-1, and RANKL. J. Cell Physiol. 190 (2002) 101-108
34. Susa M., Luong-Nguyen N.H., Cappellen D., Zamurovic N., and Gamse R. Human primary osteoclasts: in vitro generation and application as pharmacological and clinical assay. J. Transl. Med. 6 (2004) 1-12
35. Sorensen M.G., Henriksen K., Schaller S., Henriksen D.B., Nielsen F.C., Dziegel M.H., and Karsdal M.A. Characterization of osteoclasts derived from CD14+monocytes isolated from the peripheral blood. J. Bone Miner. Metab. 25 (2007) 36-45
36. Tanaka S., Nakamura I., Inoue J.-I., Oda H., and Nakamura K. Signal transduction pathways regulating osteoclast differentiation and function. J. Bone Miner. Metab. 21 (2003) 123-133
37. Theill L.E., Boyle W.J., and Penninger J.M. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu. Rev. Immunol. 20 (2002) 795-823
38. Teitelbaum S.L. Bone resorption by osteoclasts. Science 289 (2000) 1504-1508
39. Ugarova T.P., Solovjov D.A., Zhang L., Loukinov D.I., Yee V.C., Medved L.V., and Plow E.F. Identification of a novel recognition sequence for integrin alphaM beta2 within the gamma-chain of fibrinogen. J. Biol. Chem. 273 (1998) 22419-22427
40. Walsh N.C., and Gravallese E.M. Bone loss in inflammatory arthritis: mechanisms and treatment strategies. Curr. Opin. Rheumatol. 16 (2004) 419-427
41. Zhang D.E., Hetherington C.J., Gonzalez D.A., Chen H.M., and Tenen D.G. Regulation of CD14 expression during monocytic differentiation induced with 1 alpha,25-dihydroxyvitamin D3. J. Immunol. 153 (1994) 3276-3284
42. Zhuang I., Jung J.Y., Wang E.W., Houlihan P., Ramos I., Pashia M., and Chole R.A. Pseudomonas aeruginosa lipopolysaccharide induces osteoclastogenesis through a toll-like receptor 4 mediated pathway in vitro and in vivo. Laryngoscope 117 (2007) 841-847