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Volumn 19, Issue 6, 2017, Pages 1691-1702

Exosomes for the Enhanced Tissue Bioavailability and Efficacy of Curcumin

Author keywords

Anti cancer activity; Curcumin; Drug delivery; Exosomes; Toxicity

Indexed keywords

ACETONITRILE; ALCOHOL; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT;

EID: 85031763228     PISSN: None     EISSN: 15507416     Source Type: Journal    
DOI: 10.1208/s12248-017-0154-9     Document Type: Article
Times cited : (236)

References (61)
  • 1
    • 45849149639 scopus 로고    scopus 로고
    • Curcumin and cancer: an “old-age” disease with an “age-old” solution
    • COI: 1:CAS:528:DC%2BD1cXotlCgtbs%3D, PID: 18462866
    • Anand P, Sundaram C, Jhurani S, Kunnumakkara AB, Aggarwal BB. Curcumin and cancer: an “old-age” disease with an “age-old” solution. Cancer Lett. 2008;267(1):133–64. https://doi.org/10.1016/j.canlet.2008.03.025.
    • (2008) Cancer Lett , vol.267 , Issue.1 , pp. 133-164
    • Anand, P.1    Sundaram, C.2    Jhurani, S.3    Kunnumakkara, A.B.4    Aggarwal, B.B.5
  • 2
    • 84898880876 scopus 로고    scopus 로고
    • Curcumin implants, not curcumin diet, inhibit estrogen-induced mammary carcinogenesis in ACI rats
    • COI: 1:CAS:528:DC%2BC2cXlslSmt74%3D
    • Bansal SS, Kausar H, Vadhanam MV, Ravoori S, Pan J, Rai SN, et al. Curcumin implants, not curcumin diet, inhibit estrogen-induced mammary carcinogenesis in ACI rats. Cancer Prev Res. 2014;7(4):456–65. https://doi.org/10.1158/1940-6207.CAPR-13-0248.
    • (2014) Cancer Prev Res , vol.7 , Issue.4 , pp. 456-465
    • Bansal, S.S.1    Kausar, H.2    Vadhanam, M.V.3    Ravoori, S.4    Pan, J.5    Rai, S.N.6
  • 3
    • 84859741795 scopus 로고    scopus 로고
    • Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice
    • PID: 21968952
    • Zhongfa L, Chiu M, Wang J, Chen W, Yen W, Fan-Havard P, et al. Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice. Cancer Chemother Pharmacol. 2012;69(3):679–89. https://doi.org/10.1007/s00280-011-1749-y.
    • (2012) Cancer Chemother Pharmacol , vol.69 , Issue.3 , pp. 679-689
    • Zhongfa, L.1    Chiu, M.2    Wang, J.3    Chen, W.4    Yen, W.5    Fan-Havard, P.6
  • 4
    • 76749114901 scopus 로고    scopus 로고
    • Advances of cancer therapy by nanotechnology
    • PID: 19688065
    • Wang X, Wang Y, Chen ZG, Shin DM. Advances of cancer therapy by nanotechnology. Cancer Res Treat. 2009;41(1):1–11. https://doi.org/10.4143/crt.2009.41.1.1.
    • (2009) Cancer Res Treat , vol.41 , Issue.1 , pp. 1-11
    • Wang, X.1    Wang, Y.2    Chen, Z.G.3    Shin, D.M.4
  • 5
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • COI: 1:CAS:528:DC%2BD2MXpt1WlsA%3D%3D, PID: 15688077
    • Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov. 2005;4(2):145–60. https://doi.org/10.1038/nrd1632.
    • (2005) Nat Rev Drug Discov , vol.4 , Issue.2 , pp. 145-160
    • Torchilin, V.P.1
  • 6
    • 38849111818 scopus 로고    scopus 로고
    • Cytotoxicity of nanoparticles
    • COI: 1:CAS:528:DC%2BD1cXhsV2rtbg%3D, PID: 18165959
    • Lewinski N, Colvin V, Drezek R. Cytotoxicity of nanoparticles. Small. 2008;4(1):26–49. https://doi.org/10.1002/smll.200700595.
    • (2008) Small , vol.4 , Issue.1 , pp. 26-49
    • Lewinski, N.1    Colvin, V.2    Drezek, R.3
  • 7
    • 33745597580 scopus 로고    scopus 로고
    • Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety
    • COI: 1:CAS:528:DC%2BD28XmsVehtrY%3D, PID: 16484287
    • Donaldson K, Aitken R, Tran L, Stone V, Duffin R, Forrest G, et al. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci. 2006;92(1):5–22. https://doi.org/10.1093/toxsci/kfj130.
    • (2006) Toxicol Sci , vol.92 , Issue.1 , pp. 5-22
    • Donaldson, K.1    Aitken, R.2    Tran, L.3    Stone, V.4    Duffin, R.5    Forrest, G.6
  • 8
    • 33847678943 scopus 로고    scopus 로고
    • Nanoparticles: pharmacological and toxicological significance
    • COI: 1:CAS:528:DC%2BD2sXisVeis70%3D, PID: 17245366
    • Medina C, Santos-Martinez MJ, Radomski A, Corrigan OI, Radomski MW. Nanoparticles: pharmacological and toxicological significance. Br J Pharmacol. 2007;150(5):552–8. https://doi.org/10.1038/sj.bjp.0707130.
    • (2007) Br J Pharmacol , vol.150 , Issue.5 , pp. 552-558
    • Medina, C.1    Santos-Martinez, M.J.2    Radomski, A.3    Corrigan, O.I.4    Radomski, M.W.5
  • 9
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
    • COI: 1:CAS:528:DyaK1cXjtFGhtrg%3D, PID: 9619120
    • Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998;64(4):353–6. https://doi.org/10.1055/s-2006-957450.
    • (1998) Planta Med , vol.64 , Issue.4 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.6
  • 10
    • 84904471447 scopus 로고    scopus 로고
    • Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin
    • COI: 1:CAS:528:DC%2BC2cXnvFSgurs%3D, PID: 25422796
    • Grill AE, Koniar B, Panyam J. Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin. Drug Deliv Transl Res. 2014;4(4):344–52. https://doi.org/10.1007/s13346-014-0199-6.
    • (2014) Drug Deliv Transl Res , vol.4 , Issue.4 , pp. 344-352
    • Grill, A.E.1    Koniar, B.2    Panyam, J.3
  • 11
    • 84866148275 scopus 로고    scopus 로고
    • Multi-layer polymeric implants for sustained release of chemopreventives
    • COI: 1:CAS:528:DC%2BC38XhtFGrt7bP, PID: 22820161
    • Aqil F, Jeyabalan J, Kausar H, Bansal SS, Sharma RJ, Singh IP, et al. Multi-layer polymeric implants for sustained release of chemopreventives. Cancer Lett. 2012;326(1):33–40. https://doi.org/10.1016/j.canlet.2012.07.017.
    • (2012) Cancer Lett , vol.326 , Issue.1 , pp. 33-40
    • Aqil, F.1    Jeyabalan, J.2    Kausar, H.3    Bansal, S.S.4    Sharma, R.J.5    Singh, I.P.6
  • 12
    • 84865325440 scopus 로고    scopus 로고
    • Controlled-release systemic delivery—a new concept in cancer chemoprevention
    • COI: 1:CAS:528:DC%2BC38Xht1ems7%2FP, PID: 22696595
    • Gupta RC, Bansal SS, Aqil F, Jeyabalan J, Cao P, Kausar H, et al. Controlled-release systemic delivery—a new concept in cancer chemoprevention. Carcinogenesis. 2012;33(8):1608–15. https://doi.org/10.1093/carcin/bgs209.
    • (2012) Carcinogenesis , vol.33 , Issue.8 , pp. 1608-1615
    • Gupta, R.C.1    Bansal, S.S.2    Aqil, F.3    Jeyabalan, J.4    Cao, P.5    Kausar, H.6
  • 13
    • 84862994005 scopus 로고    scopus 로고
    • Curcumin implants for continuous systemic delivery: safety and biocompatibility
    • COI: 1:CAS:528:DC%2BC3MXotlygsL4%3D, PID: 25788367
    • Bansal SS, Kausar H, Aqil F, Jeyabalan J, Vadhanam MV, Gupta RC, et al. Curcumin implants for continuous systemic delivery: safety and biocompatibility. Drug Deliv Transl Res. 2011;1(4):332–41. https://doi.org/10.1007/s13346-011-0028-0.
    • (2011) Drug Deliv Transl Res , vol.1 , Issue.4 , pp. 332-341
    • Bansal, S.S.1    Kausar, H.2    Aqil, F.3    Jeyabalan, J.4    Vadhanam, M.V.5    Gupta, R.C.6
  • 14
    • 84904299687 scopus 로고    scopus 로고
    • Polymeric micelles as drug carriers: their lights and shadows
    • COI: 1:CAS:528:DC%2BC2cXhtFensLjJ, PID: 25012065
    • Yokoyama M. Polymeric micelles as drug carriers: their lights and shadows. J Drug Target. 2014;22(7):576–83. https://doi.org/10.3109/1061186X.2014.934688.
    • (2014) J Drug Target , vol.22 , Issue.7 , pp. 576-583
    • Yokoyama, M.1
  • 15
    • 85006202925 scopus 로고    scopus 로고
    • Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
    • PID: 27471669
    • Ha D, Yang N, Nadithe V. Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges. Acta Pharm Sin B. 2016;6(4):287–96. https://doi.org/10.1016/j.apsb.2016.02.001.
    • (2016) Acta Pharm Sin B , vol.6 , Issue.4 , pp. 287-296
    • Ha, D.1    Yang, N.2    Nadithe, V.3
  • 17
    • 80052831943 scopus 로고    scopus 로고
    • Exosome nanotechnology: an emerging paradigm shift in drug delivery: exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers
    • COI: 1:CAS:528:DC%2BC3MXhtFGqu7bF, PID: 21932222
    • Lakhal S, Wood MJ. Exosome nanotechnology: an emerging paradigm shift in drug delivery: exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers. BioEssays. 2011;33(10):737–41. https://doi.org/10.1002/bies.201100076.
    • (2011) BioEssays , vol.33 , Issue.10 , pp. 737-741
    • Lakhal, S.1    Wood, M.J.2
  • 18
    • 84973293346 scopus 로고    scopus 로고
    • Exosomal formulation enhances therapeutic response of celastrol against lung cancer
    • COI: 1:CAS:528:DC%2BC28Xps1Wks7c%3D, PID: 27235383
    • Aqil F, Kausar H, Agrawal AK, Jeyabalan J, Kyakulaga AH, Munagala R, et al. Exosomal formulation enhances therapeutic response of celastrol against lung cancer. Exp Mol Pathol. 2016;101(1):12–21. https://doi.org/10.1016/j.yexmp.2016.05.013.
    • (2016) Exp Mol Pathol , vol.101 , Issue.1 , pp. 12-21
    • Aqil, F.1    Kausar, H.2    Agrawal, A.K.3    Jeyabalan, J.4    Kyakulaga, A.H.5    Munagala, R.6
  • 19
    • 84951831545 scopus 로고    scopus 로고
    • Bovine milk-derived exosomes for drug delivery
    • COI: 1:CAS:528:DC%2BC2MXhvVyku7%2FM, PID: 26604130
    • Munagala R, Aqil F, Jeyabalan J, Gupta RC. Bovine milk-derived exosomes for drug delivery. Cancer Lett. 2016;371(1):48–61. https://doi.org/10.1016/j.canlet.2015.10.020.
    • (2016) Cancer Lett , vol.371 , Issue.1 , pp. 48-61
    • Munagala, R.1    Aqil, F.2    Jeyabalan, J.3    Gupta, R.C.4
  • 20
    • 84883346621 scopus 로고    scopus 로고
    • Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization
    • COI: 1:CAS:528:DC%2BC2MXksVyrs7w%3D, PID: 23982586
    • Gao H, Yang Z, Zhang S, Cao S, Shen S, Pang Z, et al. Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization. Sci Rep. 2013;3:2534. https://doi.org/10.1038/srep02534.
    • (2013) Sci Rep , vol.3 , pp. 2534
    • Gao, H.1    Yang, Z.2    Zhang, S.3    Cao, S.4    Shen, S.5    Pang, Z.6
  • 21
    • 84875258085 scopus 로고    scopus 로고
    • Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets
    • COI: 1:CAS:528:DC%2BC3sXis1OrtbY%3D, PID: 23340170
    • Kausar H, Munagala R, Bansal SS, Aqil F, Vadhanam MV, Gupta RC. Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets. Cancer Lett. 2013;332(1):35–45. https://doi.org/10.1016/j.canlet.2013.01.008.
    • (2013) Cancer Lett , vol.332 , Issue.1 , pp. 35-45
    • Kausar, H.1    Munagala, R.2    Bansal, S.S.3    Aqil, F.4    Vadhanam, M.V.5    Gupta, R.C.6
  • 22
    • 84919460678 scopus 로고    scopus 로고
    • Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer
    • COI: 1:CAS:528:DC%2BC2cXhslGjtrfO, PID: 25304375
    • Munagala R, Aqil F, Jeyabalan J, Gupta RC. Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer. Cancer Lett. 2015;356(2 Pt B):536–46. https://doi.org/10.1016/j.canlet.2014.09.037.
    • (2015) Cancer Lett , vol.356 , Issue.2 , pp. 536-546
    • Munagala, R.1    Aqil, F.2    Jeyabalan, J.3    Gupta, R.C.4
  • 23
    • 78650756464 scopus 로고    scopus 로고
    • Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice
    • COI: 1:CAS:528:DC%2BC3MXis1Wjuw%3D%3D, PID: 21187332
    • Paul PK, Gupta SK, Bhatnagar S, Panguluri SK, Darnay BG, Choi Y, et al. Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice. J Cell Biol. 2010;191(7):1395–411. https://doi.org/10.1083/jcb.201006098.
    • (2010) J Cell Biol , vol.191 , Issue.7 , pp. 1395-1411
    • Paul, P.K.1    Gupta, S.K.2    Bhatnagar, S.3    Panguluri, S.K.4    Darnay, B.G.5    Choi, Y.6
  • 24
    • 84921535683 scopus 로고    scopus 로고
    • Curcumin, a component of golden spice: from bedside to bench and back
    • Prasad S, Gupta SC, Tyagi AK, Aggarwal BB. Curcumin, a component of golden spice: from bedside to bench and back. Biotechnol Adv. 2014;32:1053-1064; https://doi.org/10.1016/j.biotechadv.2014.04.004.
    • (2014) Biotechnol Adv , vol.32 , pp. 1053-1064
    • Prasad, S.1    Gupta, S.C.2    Tyagi, A.K.3    Aggarwal, B.B.4
  • 25
    • 34548619487 scopus 로고    scopus 로고
    • Exosomes with immune modulatory features are present in human breast milk
    • COI: 1:CAS:528:DC%2BD2sXnvVymsL0%3D, PID: 17641064
    • Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, et al. Exosomes with immune modulatory features are present in human breast milk. J Immunol. 2007;179(3):1969–78.
    • (2007) J Immunol , vol.179 , Issue.3 , pp. 1969-1978
    • Admyre, C.1    Johansson, S.M.2    Qazi, K.R.3    Filen, J.J.4    Lahesmaa, R.5    Norman, M.6
  • 26
    • 77952745080 scopus 로고    scopus 로고
    • Isolation of bovine milk-derived microvesicles carrying mRNAs and microRNAs
    • COI: 1:CAS:528:DC%2BC3cXmslOns7g%3D, PID: 20434431
    • Hata T, Murakami K, Nakatani H, Yamamoto Y, Matsuda T, Aoki N. Isolation of bovine milk-derived microvesicles carrying mRNAs and microRNAs. Biochem Biophys Res Commun. 2010;396(2):528–33. https://doi.org/10.1016/j.bbrc.2010.04.135S0006-291X(10)00830-2.
    • (2010) Biochem Biophys Res Commun , vol.396 , Issue.2 , pp. 528-533
    • Hata, T.1    Murakami, K.2    Nakatani, H.3    Yamamoto, Y.4    Matsuda, T.5    Aoki, N.6
  • 27
    • 37549051274 scopus 로고    scopus 로고
    • Bioavailability of curcumin: problems and promises
    • COI: 1:CAS:528:DC%2BD2sXht12gsrnF, PID: 17999464
    • Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. Bioavailability of curcumin: problems and promises. Mol Pharm. 2007;4(6):807–18. https://doi.org/10.1021/mp700113r.
    • (2007) Mol Pharm , vol.4 , Issue.6 , pp. 807-818
    • Anand, P.1    Kunnumakkara, A.B.2    Newman, R.A.3    Aggarwal, B.B.4
  • 29
    • 51649118928 scopus 로고    scopus 로고
    • Phase II trial of curcumin in patients with advanced pancreatic cancer
    • COI: 1:CAS:528:DC%2BD1cXosFGitLw%3D, PID: 18628464
    • Dhillon N, Aggarwal BB, Newman RA, Wolff RA, Kunnumakkara AB, Abbruzzese JL, et al. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin Cancer Res. 2008;14(14):4491–9. https://doi.org/10.1158/1078-0432.CCR-08-0024.
    • (2008) Clin Cancer Res , vol.14 , Issue.14 , pp. 4491-4499
    • Dhillon, N.1    Aggarwal, B.B.2    Newman, R.A.3    Wolff, R.A.4    Kunnumakkara, A.B.5    Abbruzzese, J.L.6
  • 30
    • 67349137064 scopus 로고    scopus 로고
    • Development of curcuminoids loaded poly(butyl) cyanoacrylate nanoparticles: physicochemical characterization and stability study
    • COI: 1:CAS:528:DC%2BD1MXms1OksLY%3D, PID: 19491031
    • Mulik R, Mahadik K, Paradkar A. Development of curcuminoids loaded poly(butyl) cyanoacrylate nanoparticles: physicochemical characterization and stability study. Eur J Pharm Sci. 2009;37(3–4):395–404. https://doi.org/10.1016/j.ejps.2009.03.009.
    • (2009) Eur J Pharm Sci , vol.37 , Issue.3-4 , pp. 395-404
    • Mulik, R.1    Mahadik, K.2    Paradkar, A.3
  • 31
    • 67349107075 scopus 로고    scopus 로고
    • Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer
    • COI: 1:CAS:528:DC%2BD1MXms1Oksrg%3D, PID: 19491009
    • Shaikh J, Ankola DD, Beniwal V, Singh D, Kumar MN. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci. 2009;37(3–4):223–30. https://doi.org/10.1016/j.ejps.2009.02.019.
    • (2009) Eur J Pharm Sci , vol.37 , Issue.3-4 , pp. 223-230
    • Shaikh, J.1    Ankola, D.D.2    Beniwal, V.3    Singh, D.4    Kumar, M.N.5
  • 32
    • 85047681562 scopus 로고    scopus 로고
    • Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BD1MXktVWlurk%3D, PID: 19222903
    • Yadav VR, Suresh S, Devi K, Yadav S. Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease. J Pharm Pharmacol. 2009;61(3):311–21. https://doi.org/10.1211/jpp/61.03.0005.
    • (2009) J Pharm Pharmacol , vol.61 , Issue.3 , pp. 311-321
    • Yadav, V.R.1    Suresh, S.2    Devi, K.3    Yadav, S.4
  • 33
    • 57849106304 scopus 로고    scopus 로고
    • An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells
    • COI: 1:CAS:528:DC%2BD1cXhsFCjurvM, PID: 18840516
    • Chen C, Johnston TD, Jeon H, Gedaly R, McHugh PP, Burke TG, et al. An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells. Int J Pharm. 2009;366(1–2):133–9. https://doi.org/10.1016/j.ijpharm.2008.09.009.
    • (2009) Int J Pharm , vol.366 , Issue.1-2 , pp. 133-139
    • Chen, C.1    Johnston, T.D.2    Jeon, H.3    Gedaly, R.4    McHugh, P.P.5    Burke, T.G.6
  • 34
    • 84884994929 scopus 로고    scopus 로고
    • Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis
    • COI: 1:CAS:528:DC%2BC3sXhsF2ltb3I, PID: 24023285
    • Ranjan AP, Mukerjee A, Helson L, Gupta R, Vishwanatha JK. Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis. Anticancer Res. 2013;33(9):3603–9.
    • (2013) Anticancer Res , vol.33 , Issue.9 , pp. 3603-3609
    • Ranjan, A.P.1    Mukerjee, A.2    Helson, L.3    Gupta, R.4    Vishwanatha, J.K.5
  • 35
    • 84986905134 scopus 로고    scopus 로고
    • Lipid based nanosystems for curcumin: past, present and future
    • PID: 27306091
    • Nayak AP, Mills T, Norton I. Lipid based nanosystems for curcumin: past, present and future. Curr Pharm Des. 2016;22(27):4247–56.
    • (2016) Curr Pharm Des , vol.22 , Issue.27 , pp. 4247-4256
    • Nayak, A.P.1    Mills, T.2    Norton, I.3
  • 36
    • 84984645843 scopus 로고    scopus 로고
    • Solid lipid nanoparticles coated with cross-linked polymeric double layer for oral delivery of curcumin
    • COI: 1:CAS:528:DC%2BC28XhsVeltLzF, PID: 27588376
    • Wang T, Ma X, Lei Y, Luo Y. Solid lipid nanoparticles coated with cross-linked polymeric double layer for oral delivery of curcumin. Colloids Surf B Biointerfaces. 2016;148:1–11. https://doi.org/10.1016/j.colsurfb.2016.08.047.
    • (2016) Colloids Surf B Biointerfaces , vol.148 , pp. 1-11
    • Wang, T.1    Ma, X.2    Lei, Y.3    Luo, Y.4
  • 37
    • 33846234714 scopus 로고    scopus 로고
    • Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats
    • COI: 1:CAS:528:DC%2BD2sXntFSnsw%3D%3D, PID: 17112692
    • Maiti K, Mukherjee K, Gantait A, Saha BP, Mukherjee PK. Curcumin-phospholipid complex: preparation, therapeutic evaluation and pharmacokinetic study in rats. Int J Pharm. 2007;330(1–2):155–63. https://doi.org/10.1016/j.ijpharm.2006.09.025.
    • (2007) Int J Pharm , vol.330 , Issue.1-2 , pp. 155-163
    • Maiti, K.1    Mukherjee, K.2    Gantait, A.3    Saha, B.P.4    Mukherjee, P.K.5
  • 38
    • 80051487233 scopus 로고    scopus 로고
    • Advanced drug delivery systems of curcumin for cancer chemoprevention
    • COI: 1:CAS:528:DC%2BC3MXhtFGmtrbE
    • Bansal SS, Goel M, Aqil F, Vadhanam MV, Gupta RC. Advanced drug delivery systems of curcumin for cancer chemoprevention. Cancer Prev Res. 2011;4(8):1158–71. https://doi.org/10.1158/1940-6207.CAPR-10-0006.
    • (2011) Cancer Prev Res , vol.4 , Issue.8 , pp. 1158-1171
    • Bansal, S.S.1    Goel, M.2    Aqil, F.3    Vadhanam, M.V.4    Gupta, R.C.5
  • 39
    • 8644286802 scopus 로고    scopus 로고
    • Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells
    • COI: 1:CAS:528:DC%2BD2cXhtVWhurrI, PID: 15284116
    • Morelli AE, Larregina AT, Shufesky WJ, Sullivan ML, Stolz DB, Papworth GD, et al. Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells. Blood. 2004;104(10):3257–66. https://doi.org/10.1182/blood-2004-03-0824.
    • (2004) Blood , vol.104 , Issue.10 , pp. 3257-3266
    • Morelli, A.E.1    Larregina, A.T.2    Shufesky, W.J.3    Sullivan, M.L.4    Stolz, D.B.5    Papworth, G.D.6
  • 40
    • 71749102668 scopus 로고    scopus 로고
    • Microenvironmental pH is a key factor for exosome traffic in tumor cells
    • COI: 1:CAS:528:DC%2BD1MXhsVymu7fN, PID: 19801663
    • Parolini I, Federici C, Raggi C, Lugini L, Palleschi S, De Milito A, et al. Microenvironmental pH is a key factor for exosome traffic in tumor cells. J Biol Chem. 2009;284(49):34211–22. https://doi.org/10.1074/jbc.M109.041152.
    • (2009) J Biol Chem , vol.284 , Issue.49 , pp. 34211-34222
    • Parolini, I.1    Federici, C.2    Raggi, C.3    Lugini, L.4    Palleschi, S.5    De Milito, A.6
  • 41
    • 77957269172 scopus 로고    scopus 로고
    • Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
    • COI: 1:CAS:528:DC%2BC3cXhtlSnt7jE, PID: 20533300
    • Tian T, Wang Y, Wang H, Zhu Z, Xiao Z. Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy. J Cell Biochem. 2010;111(2):488–96. https://doi.org/10.1002/jcb.22733.
    • (2010) J Cell Biochem , vol.111 , Issue.2 , pp. 488-496
    • Tian, T.1    Wang, Y.2    Wang, H.3    Zhu, Z.4    Xiao, Z.5
  • 42
    • 84875520481 scopus 로고    scopus 로고
    • Dynamics of exosome internalization and trafficking
    • COI: 1:CAS:528:DC%2BC3sXktleqsr0%3D, PID: 23254476
    • Tian T, Zhu YL, FH H, Wang YY, Huang NP, Xiao ZD. Dynamics of exosome internalization and trafficking. J Cell Physiol. 2013;228(7):1487–95. https://doi.org/10.1002/jcp.24304.
    • (2013) J Cell Physiol , vol.228 , Issue.7 , pp. 1487-1495
    • Tian, T.1    Zhu, Y.L.2    Fh, H.3    Wang, Y.Y.4    Huang, N.P.5    Xiao, Z.D.6
  • 43
  • 44
    • 85018377351 scopus 로고    scopus 로고
    • Curcumin encapsulated in milk exosomes resists human digestion and possesses enhanced intestinal permeability in vitro
    • Vashisht M, Rani P, Onteru SK, Singh D. Curcumin encapsulated in milk exosomes resists human digestion and possesses enhanced intestinal permeability in vitro. Appl Biochem Biotechnol. 2017; https://doi.org/10.1007/s12010-017-2478-4.
    • (2017) Appl Biochem Biotechnol
    • Vashisht, M.1    Rani, P.2    Onteru, S.K.3    Singh, D.4
  • 45
    • 85027875352 scopus 로고    scopus 로고
    • Human milk exosomes and their microRNAs survive digestion in vitro and are taken up by human intestinal cells
    • Liao Y, Du X, Li J, Lonnerdal B. Human milk exosomes and their microRNAs survive digestion in vitro and are taken up by human intestinal cells. Mol Nutr Food Res. 2017; https://doi.org/10.1002/mnfr.201700082.
    • (2017) Mol Nutr Food Res
    • Liao, Y.1    Du, X.2    Li, J.3    Lonnerdal, B.4
  • 46
    • 75649119273 scopus 로고    scopus 로고
    • Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs
    • COI: 1:CAS:528:DC%2BC3cXhtF2mtA%3D%3D, PID: 19850715
    • Chen TS, Lai RC, Lee MM, Choo AB, Lee CN, Lim SK. Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs. Nucleic Acids Res. 2010;38(1):215–24. https://doi.org/10.1093/nar/gkp857.
    • (2010) Nucleic Acids Res , vol.38 , Issue.1 , pp. 215-224
    • Chen, T.S.1    Lai, R.C.2    Lee, M.M.3    Choo, A.B.4    Lee, C.N.5    Lim, S.K.6
  • 47
    • 84903545653 scopus 로고    scopus 로고
    • Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles
    • COI: 1:CAS:528:DC%2BC2cXotFerur8%3D, PID: 24842810
    • Mu J, Zhuang X, Wang Q, Jiang H, Deng ZB, Wang B, et al. Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles. Mol Nutr Food Res. 2014;58(7):1561–73. https://doi.org/10.1002/mnfr.201300729.
    • (2014) Mol Nutr Food Res , vol.58 , Issue.7 , pp. 1561-1573
    • Mu, J.1    Zhuang, X.2    Wang, Q.3    Jiang, H.4    Deng, Z.B.5    Wang, B.6
  • 48
    • 79956337181 scopus 로고    scopus 로고
    • Comparing cellular uptake and cytotoxicity of targeted drug carriers in cancer cell lines with different drug resistance mechanisms
    • COI: 1:CAS:528:DC%2BC3MXnvVGqu78%3D, PID: 21094277
    • Lei T, Srinivasan S, Tang Y, Manchanda R, Nagesetti A, Fernandez-Fernandez A, et al. Comparing cellular uptake and cytotoxicity of targeted drug carriers in cancer cell lines with different drug resistance mechanisms. Nanomedicine. 2011;7(3):324–32. https://doi.org/10.1016/j.nano.2010.11.004.
    • (2011) Nanomedicine , vol.7 , Issue.3 , pp. 324-332
    • Lei, T.1    Srinivasan, S.2    Tang, Y.3    Manchanda, R.4    Nagesetti, A.5    Fernandez-Fernandez, A.6
  • 49
    • 84929807408 scopus 로고    scopus 로고
    • Grapefruit-derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites
    • COI: 1:CAS:528:DC%2BC2MXpvFSjurs%3D, PID: 25883092
    • Wang Q, Ren Y, Mu J, Egilmez NK, Zhuang X, Deng Z, et al. Grapefruit-derived nanovectors use an activated leukocyte trafficking pathway to deliver therapeutic agents to inflammatory tumor sites. Cancer Res. 2015;75(12):2520–9. https://doi.org/10.1158/0008-5472.CAN-14-3095.
    • (2015) Cancer Res , vol.75 , Issue.12 , pp. 2520-2529
    • Wang, Q.1    Ren, Y.2    Mu, J.3    Egilmez, N.K.4    Zhuang, X.5    Deng, Z.6
  • 50
    • 84935026792 scopus 로고    scopus 로고
    • Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio
    • COI: 1:CAS:528:DC%2BC2MXht1Omsrk%3D, PID: 25609010
    • Yang T, Martin P, Fogarty B, Brown A, Schurman K, Phipps R, et al. Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio. Pharm Res. 2015;32(6):2003–14. https://doi.org/10.1007/s11095-014-1593-y.
    • (2015) Pharm Res , vol.32 , Issue.6 , pp. 2003-2014
    • Yang, T.1    Martin, P.2    Fogarty, B.3    Brown, A.4    Schurman, K.5    Phipps, R.6
  • 51
    • 84875863240 scopus 로고    scopus 로고
    • Silica-coated flexible liposomes as a nanohybrid delivery system for enhanced oral bioavailability of curcumin
    • COI: 1:CAS:528:DC%2BC38XhvV2jsL3F, PID: 23233804
    • Li C, Zhang Y, Su T, Feng L, Long Y, Chen Z. Silica-coated flexible liposomes as a nanohybrid delivery system for enhanced oral bioavailability of curcumin. Int J Nanomedicine. 2012;7:5995–6002. https://doi.org/10.2147/IJN.S38043.
    • (2012) Int J Nanomedicine , vol.7 , pp. 5995-6002
    • Li, C.1    Zhang, Y.2    Su, T.3    Feng, L.4    Long, Y.5    Chen, Z.6
  • 52
    • 84877031136 scopus 로고    scopus 로고
    • Highly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer’s disease Tg2576 mice
    • COI: 1:CAS:528:DC%2BC3sXlsF2hsLc%3D, PID: 23229335
    • Cheng KK, Yeung CF, Ho SW, Chow SF, Chow AH, Baum L. Highly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer’s disease Tg2576 mice. AAPS J. 2013;15(2):324–36. https://doi.org/10.1208/s12248-012-9444-4.
    • (2013) AAPS J , vol.15 , Issue.2 , pp. 324-336
    • Cheng, K.K.1    Yeung, C.F.2    Ho, S.W.3    Chow, S.F.4    Chow, A.H.5    Baum, L.6
  • 53
    • 84980361406 scopus 로고    scopus 로고
    • Chronic inflammation links cancer and Parkinson’s disease
    • PID: 27375474
    • Li Z, Zheng Z, Ruan J, Li Z, Tzeng CM. Chronic inflammation links cancer and Parkinson’s disease. Front Aging Neurosci. 2016;8:126. https://doi.org/10.3389/fnagi.2016.00126.
    • (2016) Front Aging Neurosci , vol.8 , pp. 126
    • Li, Z.1    Zheng, Z.2    Ruan, J.3    Li, Z.4    Tzeng, C.M.5
  • 54
    • 77956264919 scopus 로고    scopus 로고
    • A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes
    • COI: 1:CAS:528:DC%2BC3cXnvVShu7c%3D, PID: 20571541
    • Sun D, Zhuang X, Xiang X, Liu Y, Zhang S, Liu C, et al. A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes. Mol Ther. 2010;18(9):1606–14. https://doi.org/10.1038/mt.2010.105.
    • (2010) Mol Ther , vol.18 , Issue.9 , pp. 1606-1614
    • Sun, D.1    Zhuang, X.2    Xiang, X.3    Liu, Y.4    Zhang, S.5    Liu, C.6
  • 55
    • 84893973489 scopus 로고    scopus 로고
    • Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice
    • COI: 1:CAS:528:DC%2BC28XntlaisbY%3D, PID: 24520218
    • Prasad S, Tyagi AK, Aggarwal BB. Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. Cancer Res Treat. 2014;46(1):2–18. https://doi.org/10.4143/crt.2014.46.1.2.
    • (2014) Cancer Res Treat , vol.46 , Issue.1 , pp. 2-18
    • Prasad, S.1    Tyagi, A.K.2    Aggarwal, B.B.3
  • 57
    • 84983287964 scopus 로고    scopus 로고
    • Novel curcumin-loaded human serum albumin nanoparticles surface functionalized with folate: characterization and in vitro/vivo evaluation
    • PID: 27574403
    • Song Z, Lu Y, Zhang X, Wang H, Han J, Dong C. Novel curcumin-loaded human serum albumin nanoparticles surface functionalized with folate: characterization and in vitro/vivo evaluation. Drug Des Devel Ther. 2016;10:2643–9. https://doi.org/10.2147/DDDT.S112039.
    • (2016) Drug Des Devel Ther , vol.10 , pp. 2643-2649
    • Song, Z.1    Lu, Y.2    Zhang, X.3    Wang, H.4    Han, J.5    Dong, C.6
  • 58
    • 77950648249 scopus 로고    scopus 로고
    • Effect of denaturation of alpha-lactalbumin on the formation of BAMLET (bovine alpha-lactalbumin made lethal to tumor cells)
    • COI: 1:CAS:528:DC%2BC3cXjt1emsrw%3D, PID: 20232795
    • Liskova K, Kelly AL, O'Brien N, Brodkorb A. Effect of denaturation of alpha-lactalbumin on the formation of BAMLET (bovine alpha-lactalbumin made lethal to tumor cells). J Agric Food Chem. 2010;58(7):4421–7. https://doi.org/10.1021/jf903901j.
    • (2010) J Agric Food Chem , vol.58 , Issue.7 , pp. 4421-4427
    • Liskova, K.1    Kelly, A.L.2    O'Brien, N.3    Brodkorb, A.4
  • 59
    • 84896274052 scopus 로고    scopus 로고
    • Oleic acid may be the key contributor in the BAMLET-induced erythrocyte hemolysis and tumoricidal action
    • COI: 1:CAS:528:DC%2BC3sXhsV2gs7nL, PID: 24039698
    • Hoque M, Dave S, Gupta P, Saleemuddin M. Oleic acid may be the key contributor in the BAMLET-induced erythrocyte hemolysis and tumoricidal action. PLoS One. 2013;8(9):e68390. https://doi.org/10.1371/journal.pone.0068390.
    • (2013) PLoS One , vol.8 , Issue.9
    • Hoque, M.1    Dave, S.2    Gupta, P.3    Saleemuddin, M.4
  • 60
    • 84979782485 scopus 로고    scopus 로고
    • Structure and potential cellular targets of HAMLET-like anti-cancer compounds made from milk components
    • PID: 26626257
    • Rath EM, Duff AP, Hakansson AP, Vacher CS, Liu GJ, Knott RB, et al. Structure and potential cellular targets of HAMLET-like anti-cancer compounds made from milk components. J Pharm Pharm Sci. 2015;18(4):773–824.
    • (2015) J Pharm Pharm Sci , vol.18 , Issue.4 , pp. 773-824
    • Rath, E.M.1    Duff, A.P.2    Hakansson, A.P.3    Vacher, C.S.4    Liu, G.J.5    Knott, R.B.6
  • 61
    • 73949096838 scopus 로고    scopus 로고
    • BAMLET activates a lysosomal cell death program in cancer cells
    • COI: 1:CAS:528:DC%2BC3cXktVOhsA%3D%3D, PID: 20053771
    • Rammer P, Groth-Pedersen L, Kirkegaard T, Daugaard M, Rytter A, Szyniarowski P, et al. BAMLET activates a lysosomal cell death program in cancer cells. Mol Cancer Ther. 2010;9(1):24–32. https://doi.org/10.1158/1535-7163.MCT-09-0559.
    • (2010) Mol Cancer Ther , vol.9 , Issue.1 , pp. 24-32
    • Rammer, P.1    Groth-Pedersen, L.2    Kirkegaard, T.3    Daugaard, M.4    Rytter, A.5    Szyniarowski, P.6


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