Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem

ACS Infectious Diseases

Volumn 3, Issue 10, 2017, Pages 711-717

  Tehrani, Kamaleddin Haj Mohammad Ebrahim ^a   Martin, Nathaniel I ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

antibiotic resistance; MBL inhibitor; metallo lactamase; synergy; zinc binding

Indexed keywords

2 MERCAPTO 3 PHENYLPROPIONIC ACID 4; BETA LACTAMASE INHIBITOR; CEFOPERAZONE; MEROPENEM; METALLO BETA LACTAMASE; THIOL DERIVATIVE; THIOMANDELIC ACID 3; UNCLASSIFIED DRUG; BETA LACTAM; BETA LACTAMASE; CARBAPENEM DERIVATIVE; THIENAMYCIN DERIVATIVE; THIOL BETA-LACTAMASE;

ARTICLE; BACTERIUM ISOLATE; BIOPHYSICS; CORRELATION ANALYSIS; DRUG BINDING; DRUG POTENTIATION; DRUG STRUCTURE; GRAM NEGATIVE BACTERIUM; HYDROLYSIS; ISOTHERMAL TITRATION CALORIMETRY; KLEBSIELLA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; ANTIBIOTIC RESISTANCE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; METABOLISM;

BETA-LACTAMASE INHIBITORS; BETA-LACTAMASES; BETA-LACTAMS; CARBAPENEMS; CEFOPERAZONE; DRUG RESISTANCE, BACTERIAL; GRAM-NEGATIVE BACTERIA; MOLECULAR STRUCTURE; SULFHYDRYL COMPOUNDS; THIENAMYCINS;

EID: 85031491103     PISSN: None     EISSN: 23738227     Source Type: Journal    
DOI: 10.1021/acsinfecdis.7b00094     Document Type: Article

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