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Volumn 8, Issue 47, 2017, Pages 83207-83224

Inhibition of cell cycle progression by the hydroxytyrosol- cetuximab combination yields enhanced chemotherapeutic efficacy in colon cancer cells

Author keywords

AIF dependent apoptosis; Cell cycle; Cetuximab; Colon cancer; Hydroxytyrosol

Indexed keywords

APOPTOSIS INDUCING FACTOR; CETUXIMAB; CYCLIN B; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN E; EPIDERMAL GROWTH FACTOR; HYDROXYTYROSOL; OLIVE OIL; PROTEIN P21; PROTEIN P27;

EID: 85030867071     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.20544     Document Type: Article
Times cited : (31)

References (32)
  • 2
    • 77955762194 scopus 로고    scopus 로고
    • Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis
    • Terzuoli E, Donnini S, Giachetti A, Iñiguez MA, Fresno M, Melillo G, Ziche M. Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis. Clin Cancer Res. 2010; 16: 4207-4216.
    • (2010) Clin Cancer Res , vol.16 , pp. 4207-4216
    • Terzuoli, E.1    Donnini, S.2    Giachetti, A.3    Iñiguez, M.A.4    Fresno, M.5    Melillo, G.6    Ziche, M.7
  • 3
    • 84959499432 scopus 로고    scopus 로고
    • Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation
    • Terzuoli E, Giachetti A, Ziche M, Donnini S. Hydroxytyrosol, a product from olive oil, reduces colon cancer growth by enhancing epidermal growth factor receptor degradation. Mol Nutr Food Res. 2016; 60: 519-529.
    • (2016) Mol Nutr Food Res , vol.60 , pp. 519-529
    • Terzuoli, E.1    Giachetti, A.2    Ziche, M.3    Donnini, S.4
  • 4
    • 33644847101 scopus 로고    scopus 로고
    • Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation
    • Fabiani R, De Bartolomeo A, Rosignoli P, Servili M, Selvaggini R, Montedoro GF, Di Saverio C, Morozzi G. Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation. J Nutr. 2006; 136: 614-619.
    • (2006) J Nutr , vol.136 , pp. 614-619
    • Fabiani, R.1    De Bartolomeo, A.2    Rosignoli, P.3    Servili, M.4    Selvaggini, R.5    Montedoro, G.F.6    Di Saverio, C.7    Morozzi, G.8
  • 5
    • 38149050388 scopus 로고    scopus 로고
    • Inhibition of cell cycle progression by hydroxytyrosol is associated with upregulation of cyclindependent protein kinase inhibitors p21(WAF1/Cip1) and p27(Kip1) and with induction of differentiation in HL60 cells
    • Fabiani R, Rosignoli P, De Bartolomeo A, Fuccelli R, Morozzi G. Inhibition of cell cycle progression by hydroxytyrosol is associated with upregulation of cyclindependent protein kinase inhibitors p21(WAF1/Cip1) and p27(Kip1) and with induction of differentiation in HL60 cells. J Nutr. 2008; 138: 42-48.
    • (2008) J Nutr , vol.138 , pp. 42-48
    • Fabiani, R.1    Rosignoli, P.2    De Bartolomeo, A.3    Fuccelli, R.4    Morozzi, G.5
  • 6
    • 68149181262 scopus 로고    scopus 로고
    • Production of hydrogen peroxide is responsible for the induction of apoptosis by hydroxytyrosol on HL60 cells
    • Fabiani R, Fuccelli R, Pieravanti F, De Bartolomeo A, Morozzi G. Production of hydrogen peroxide is responsible for the induction of apoptosis by hydroxytyrosol on HL60 cells. Mol Nutr Food Res. 2009; 53: 887-896.
    • (2009) Mol Nutr Food Res , vol.53 , pp. 887-896
    • Fabiani, R.1    Fuccelli, R.2    Pieravanti, F.3    De Bartolomeo, A.4    Morozzi, G.5
  • 8
    • 79960880713 scopus 로고    scopus 로고
    • Olive oil intake is inversely related to cancer prevalence: a systematic review and a meta-analysis of 13,800 patients and 23,340 controls in 19 observational studies
    • Psaltopoulou T, Kosti RI, Haidopoulos D, Dimopoulos M, Panagiotakos DB. Olive oil intake is inversely related to cancer prevalence: a systematic review and a meta-analysis of 13,800 patients and 23,340 controls in 19 observational studies. Lipids Health Dis. 2011; 10: 127.
    • (2011) Lipids Health Dis , vol.10 , pp. 127
    • Psaltopoulou, T.1    Kosti, R.I.2    Haidopoulos, D.3    Dimopoulos, M.4    Panagiotakos, D.B.5
  • 9
    • 77954543394 scopus 로고    scopus 로고
    • Cardioprotective and neuroprotective roles of oleuropein in olive
    • Omar SH. Cardioprotective and neuroprotective roles of oleuropein in olive. Saudi Pharm J. 2010; 18: 111-121.
    • (2010) Saudi Pharm J , vol.18 , pp. 111-121
    • Omar, S.H.1
  • 10
    • 33748325937 scopus 로고    scopus 로고
    • Effect of dietary virgin olive oil on urinary excretion of etheno-DNA adducts
    • Hillestrøm PR, Covas MI, Poulsen HE. Effect of dietary virgin olive oil on urinary excretion of etheno-DNA adducts. Free Radic Biol Med. 2006; 41: 1133-1138.
    • (2006) Free Radic Biol Med , vol.41 , pp. 1133-1138
    • Hillestrøm, P.R.1    Covas, M.I.2    Poulsen, H.E.3
  • 11
    • 0032995732 scopus 로고    scopus 로고
    • Olive oil hydroxytyrosol protects human erythrocytes against oxidative damages
    • Manna C, Galletti P, Cucciolla V, Montedoro G, Zappia V. Olive oil hydroxytyrosol protects human erythrocytes against oxidative damages. J Nutr Biochem. 1999; 10: 159-165.
    • (1999) J Nutr Biochem , vol.10 , pp. 159-165
    • Manna, C.1    Galletti, P.2    Cucciolla, V.3    Montedoro, G.4    Zappia, V.5
  • 12
    • 85021001550 scopus 로고    scopus 로고
    • Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway
    • Huang YF, Zhu DJ, Chen XW, Chen QK, Luo ZT, Liu CC, Wang GX, Zhang WJ, Liao NZ. Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway. Oncotarget. 2017; 8: 40264-40275. https://doi.org/10.18632/oncotarget.16828.
    • (2017) Oncotarget , vol.8 , pp. 40264-40275
    • Huang, Y.F.1    Zhu, D.J.2    Chen, X.W.3    Chen, Q.K.4    Luo, Z.T.5    Liu, C.C.6    Wang, G.X.7    Zhang, W.J.8    Liao, N.Z.9
  • 13
    • 84994634405 scopus 로고    scopus 로고
    • Extra-virgin olive oil phenols block cell cycle progression and modulate chemotherapeutic toxicity in bladder cancer cells
    • Coccia A, Mosca L, Puca R, Mangino G, Rossi A, Lendaro E. Extra-virgin olive oil phenols block cell cycle progression and modulate chemotherapeutic toxicity in bladder cancer cells. Oncol Rep. 2016; 36: 3095-3104.
    • (2016) Oncol Rep , vol.36 , pp. 3095-3104
    • Coccia, A.1    Mosca, L.2    Puca, R.3    Mangino, G.4    Rossi, A.5    Lendaro, E.6
  • 14
    • 33845973029 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) antibody downregulates mutant receptors and inhibits tumors expressing EGFR mutations
    • Perez-Torres M, Guix M, Gonzalez A, Arteaga CL. Epidermal growth factor receptor (EGFR) antibody downregulates mutant receptors and inhibits tumors expressing EGFR mutations. J Biol Chem. 2006; 281: 40183-40192.
    • (2006) J Biol Chem , vol.281 , pp. 40183-40192
    • Perez-Torres, M.1    Guix, M.2    Gonzalez, A.3    Arteaga, C.L.4
  • 17
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: role of cyclins, cyclin-dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs)
    • Grana X, Reddy P. Cell cycle control in mammalian cells: role of cyclins, cyclin-dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs). Oncogene. 1995; 11: 211-219.
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Grana, X.1    Reddy, P.2
  • 18
    • 0033735581 scopus 로고    scopus 로고
    • Cell cycle checkpoints and their inactivation in human cancer
    • Molinari M. Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif. 2000; 33: 261-274.
    • (2000) Cell Prolif , vol.33 , pp. 261-274
    • Molinari, M.1
  • 19
    • 67649424560 scopus 로고    scopus 로고
    • p21 in cancer: intricate networks and multiple activities
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer. 2009; 9: 400-414.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 20
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature. 2004; 432: 316-323.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 21
    • 0028927179 scopus 로고
    • P53, cell cycle control and apoptosis: implications for cancer
    • Kastan MB, Canman CE, Leonard CJ. P53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev. 1995; 14: 3-15.
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 3-15
    • Kastan, M.B.1    Canman, C.E.2    Leonard, C.J.3
  • 22
    • 0033574614 scopus 로고    scopus 로고
    • Mechanisms of cyclin-dependent kinase regulation: structures of cdks, their cyclin activators, and CIP and INK4 inhibitors
    • Pavletich NP. Mechanisms of cyclin-dependent kinase regulation: structures of cdks, their cyclin activators, and CIP and INK4 inhibitors. J Mol Biol. 1999; 287: 821-828.
    • (1999) J Mol Biol , vol.287 , pp. 821-828
    • Pavletich, N.P.1
  • 23
    • 85020944451 scopus 로고    scopus 로고
    • Cell cycle: division enzyme regulates metabolism
    • Krall AS, Christofk HR. Cell cycle: division enzyme regulates metabolism. Nature. 2017; 546: 357-358. https://doi.org/10.1038/nature22504.
    • (2017) Nature , vol.546 , pp. 357-358
    • Krall, A.S.1    Christofk, H.R.2
  • 24
    • 68149181871 scopus 로고    scopus 로고
    • Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1
    • Corona G, Deiana M, Incani A, Vauzour D, Dessì MA, Spencer JP. Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1. Mol Nutr Food Res. 2009; 53: 897-903.
    • (2009) Mol Nutr Food Res , vol.53 , pp. 897-903
    • Corona, G.1    Deiana, M.2    Incani, A.3    Vauzour, D.4    Dessì, M.A.5    Spencer, J.P.6
  • 25
    • 77955038334 scopus 로고    scopus 로고
    • The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex
    • Li X, Fan Z. The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex. Cancer Res. 2010; 70: 5942-5952.
    • (2010) Cancer Res , vol.70 , pp. 5942-5952
    • Li, X.1    Fan, Z.2
  • 26
    • 85020624641 scopus 로고    scopus 로고
    • Mechanisms underlying skin disorders induced by EGFR inhibitors
    • Holcmann M, Sibilia M. Mechanisms underlying skin disorders induced by EGFR inhibitors. Mol Cell Oncol. 2015; 2: e1004969.
    • (2015) Mol Cell Oncol , vol.2
    • Holcmann, M.1    Sibilia, M.2
  • 29
    • 34547758527 scopus 로고    scopus 로고
    • EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways
    • Donnini S, Finetti F, Solito R, Terzuoli E, Sacchetti A, Morbidelli L, Patrignani P, Ziche M. EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways. FASEB J. 2007; 21: 2418-2430.
    • (2007) FASEB J , vol.21 , pp. 2418-2430
    • Donnini, S.1    Finetti, F.2    Solito, R.3    Terzuoli, E.4    Sacchetti, A.5    Morbidelli, L.6    Patrignani, P.7    Ziche, M.8
  • 31
    • 84956833568 scopus 로고    scopus 로고
    • Neuroprotective effects of Castanea sativa Mill. bark extract in human neuroblastoma cells subjected to oxidative stress
    • Brizi C, Santulli C, Micucci M, Budriesi R, Chiarini A, Aldinucci C, Frosini M. Neuroprotective effects of Castanea sativa Mill. bark extract in human neuroblastoma cells subjected to oxidative stress. J Cell Biochem. 2016; 117: 510-520.
    • (2016) J Cell Biochem , vol.117 , pp. 510-520
    • Brizi, C.1    Santulli, C.2    Micucci, M.3    Budriesi, R.4    Chiarini, A.5    Aldinucci, C.6    Frosini, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.