Incorporation of functional elements enhances the antitumor capacity of CAR T cells

Experimental Hematology and Oncology

Volumn 6, Issue 1, 2017, Pages

  Qin, Le ^a   Zhao, Ruocong ^a   Li, Peng ^a  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

Author keywords

CAR T cells; Chemotherapeutic drugs; Cytokines; Hypoxia; Immune checkpoint molecules; Kinase inhibitors; Tumor microenvironment

Indexed keywords

CARBONATE DEHYDRATASE IX; CATALASE; CD19 ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GAMMA INTERFERON; IBRUTINIB; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; LENALIDOMIDE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; TISAGENLECLEUCEL T;

ANTIGEN PRESENTING CELL; ANTINEOPLASTIC ACTIVITY; CANCER REGRESSION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL HYPOXIA; CHRONIC LYMPHATIC LEUKEMIA; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CYTOKINE RELEASE; ENZYME INHIBITION; GLIOBLASTOMA; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MANTLE CELL LYMPHOMA; NATURAL KILLER CELL; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT;

EID: 85030859966     PISSN: None     EISSN: 21623619     Source Type: Journal    
DOI: 10.1186/s40164-017-0088-z     Document Type: Review

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