Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells

Cell

Volumn 167, Issue 2, 2016, Pages 405-418.e13

  Boice, Michael ^a,b   Salloum, Darin ^a   Mourcin, Frederic ^c   Sanghvi, Viraj ^a   Amin, Rada ^c   Oricchio, Elisa ^d   Jiang, Man ^a   Mottok, Anja ^e   Denis Lagache, Nicolas ^f   Ciriello, Giovanni ^g,h   Tam, Wayne ⁱ   Teruya Feldstein, Julie ^j   de Stanchina, Elisa ^a   Chan, Wing C ^k   Malek, Sami N ^l   Ennishi, Daisuke ^e   Brentjens, Renier J ^a   Gascoyne, Randy D ^e   Cogné, Michel ^f   Tarte, Karin ^c   Wendel, Hans Guido ^a   more..

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c INSERM U917   (France)

^d SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^f UNIVERSITY OF LIMOGES   (France)

^g UNIVERSITY OF LAUSANNE   (Switzerland)

^h SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

ⁱ WEILL CORNELL MEDICAL COLLEGE   (United States)

^j MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^k Memorial Sloan Kettering Cancer Center ^*  (United States)

^l UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

B AND T LYMPHOCYTE ATTENUATOR RECEPTOR; BLNK PROTEIN; BRUTON TYROSINE KINASE; CXCL13 CHEMOKINE; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; HERPESVIRUS ENTRY MEDIATOR; I KAPPA B; INTERLEUKIN 21; INTERLEUKIN 4; LYMPHOCYTE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; PROTEIN BCL 2; PROTEIN KINASE SYK; STAT6 PROTEIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; BTLA PROTEIN, HUMAN; CD19 ANTIGEN; HYBRID PROTEIN; IMMUNOGLOBULIN RECEPTOR; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE ACTIVATION; CANCER INHIBITION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INTERACTION; CELL LYSATE; CELL PROLIFERATION; CHIMERIC ANTIGEN RECEPTOR T CELL; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DEVELOPMENT; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; FOLLICULAR LYMPHOMA; FRAMESHIFT MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TISSUE MICROARRAY; TUMOR XENOGRAFT; TUNEL ASSAY; WESTERN BLOTTING; ADOPTIVE TRANSFER; ANIMAL; B LYMPHOCYTE; CHEMISTRY; DRUG SCREENING; GENETICS; IMMUNOLOGY; LYMPHOMA, FOLLICULAR; METABOLISM; NEOPLASMS, EXPERIMENTAL; PROCEDURES; PROTEIN DOMAIN; PROTEIN ENGINEERING; TUMOR MICROENVIRONMENT;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD19; B-LYMPHOCYTES; CELL PROLIFERATION; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOMA, FOLLICULAR; MICE; NEOPLASMS, EXPERIMENTAL; PROTEIN DOMAINS; PROTEIN ENGINEERING; RECEPTORS, IMMUNOLOGIC; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 14; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84990857167     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.08.032     Document Type: Article

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