메뉴 건너뛰기




Volumn 50, Issue , 2017, Pages 16-25

Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice

Author keywords

Gut microbiota; Insulin sensitivity; Probiotics

Indexed keywords

BACTERIAL DNA; BACTERIUM LIPOPOLYSACCHARIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; JANUS KINASE 2; LEPTIN; MYELOID DIFFERENTIATION FACTOR 88; OCCLUDIN; PROBIOTIC AGENT; PROTEIN ZO1; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

EID: 85030094537     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2017.08.006     Document Type: Article
Times cited : (203)

References (66)
  • 1
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn, S.E., Hull, R.L., Utzschneider, K.M., Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444:7121 (2006), 840–846.
    • (2006) Nature , vol.444 , Issue.7121 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 2
  • 3
    • 84983784787 scopus 로고    scopus 로고
    • Linking gut microbiota and inflammation to obesity and insulin resistance
    • Saad, M.J., Santos, A., Prada, P.O., Linking gut microbiota and inflammation to obesity and insulin resistance. Physiology (Bethesda) 31:4 (2016), 283–293.
    • (2016) Physiology (Bethesda) , vol.31 , Issue.4 , pp. 283-293
    • Saad, M.J.1    Santos, A.2    Prada, P.O.3
  • 4
    • 80052278497 scopus 로고    scopus 로고
    • Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
    • Amar, J., Chabo, C., Waget, A., Klopp, P., Vachoux, C., Bermudez-Humaran, L.G., et al. Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. EMBO Mol Med 3:9 (2011), 559–572.
    • (2011) EMBO Mol Med , vol.3 , Issue.9 , pp. 559-572
    • Amar, J.1    Chabo, C.2    Waget, A.3    Klopp, P.4    Vachoux, C.5    Bermudez-Humaran, L.G.6
  • 5
    • 77958615207 scopus 로고    scopus 로고
    • Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4)
    • Aronsson, L., Huang, Y., Parini, P., Korach-Andre, M., Hakansson, J., Gustafsson, J.A., et al. Decreased fat storage by Lactobacillus paracasei is associated with increased levels of angiopoietin-like 4 protein (ANGPTL4). PLoS One 5:9 (2010), 1–7.
    • (2010) PLoS One , vol.5 , Issue.9 , pp. 1-7
    • Aronsson, L.1    Huang, Y.2    Parini, P.3    Korach-Andre, M.4    Hakansson, J.5    Gustafsson, J.A.6
  • 6
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • Cani, P.D., Amar, J., Iglesias, M.A., Poggi, M., Knauf, C., Bastelica, D., et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 56:7 (2007), 1761–1772.
    • (2007) Diabetes , vol.56 , Issue.7 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3    Poggi, M.4    Knauf, C.5    Bastelica, D.6
  • 7
    • 84866141702 scopus 로고    scopus 로고
    • Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice
    • Carvalho, B.M., Guadagnini, D., Tsukumo, D.M., Schenka, A.A., Latuf-Filho, P., Vassallo, J., et al. Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice. Diabetologia 55:10 (2012), 2823–2834.
    • (2012) Diabetologia , vol.55 , Issue.10 , pp. 2823-2834
    • Carvalho, B.M.1    Guadagnini, D.2    Tsukumo, D.M.3    Schenka, A.A.4    Latuf-Filho, P.5    Vassallo, J.6
  • 8
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P.J., Ley, R.E., Mahowald, M.A., Magrini, V., Mardis, E.R., Gordon, J.I., An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444:7122 (2006), 1027–1031.
    • (2006) Nature , vol.444 , Issue.7122 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 9
    • 84930185714 scopus 로고    scopus 로고
    • TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation
    • Velloso, L.A., Folli, F., Saad, M.J., TLR4 at the crossroads of nutrients, gut microbiota, and metabolic inflammation. Endocr Rev 36:3 (2015), 245–271.
    • (2015) Endocr Rev , vol.36 , Issue.3 , pp. 245-271
    • Velloso, L.A.1    Folli, F.2    Saad, M.J.3
  • 10
    • 84902278845 scopus 로고    scopus 로고
    • Gut microbiota composition and its effects on obesity and insulin resistance
    • Caricilli, A.M., Saad, M.J., Gut microbiota composition and its effects on obesity and insulin resistance. Curr Opin Clin Nutr Metab Care 17:4 (2014), 312–318.
    • (2014) Curr Opin Clin Nutr Metab Care , vol.17 , Issue.4 , pp. 312-318
    • Caricilli, A.M.1    Saad, M.J.2
  • 11
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K.S., Manichanh, C., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464:7285 (2010), 59–65.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 12
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • Tremaroli, V., Backhed, F., Functional interactions between the gut microbiota and host metabolism. Nature 489:7415 (2012), 242–249.
    • (2012) Nature , vol.489 , Issue.7415 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 13
    • 84908545853 scopus 로고    scopus 로고
    • Gut microbiota, nutrient sensing and energy balance
    • Duca, F.A., Lam, T.K., Gut microbiota, nutrient sensing and energy balance. Diabetes Obes Metab 16:Suppl. 1 (2014), 68–76.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 68-76
    • Duca, F.A.1    Lam, T.K.2
  • 15
    • 8144226856 scopus 로고    scopus 로고
    • The gut microbiota as an environmental factor that regulates fat storage
    • Backhed, F., Ding, H., Wang, T., Hooper, L.V., Koh, G.Y., Nagy, A., et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A 101:44 (2004), 15718–15723.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.44 , pp. 15718-15723
    • Backhed, F.1    Ding, H.2    Wang, T.3    Hooper, L.V.4    Koh, G.Y.5    Nagy, A.6
  • 16
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani, P.D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A.M., Delzenne, N.M., et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes 57:6 (2008), 1470–1481.
    • (2008) Diabetes , vol.57 , Issue.6 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3    Waget, A.4    Neyrinck, A.M.5    Delzenne, N.M.6
  • 17
    • 34848912627 scopus 로고    scopus 로고
    • Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
    • Cani, P.D., Neyrinck, A.M., Fava, F., Knauf, C., Burcelin, R.G., Tuohy, K.M., et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia 50:11 (2007), 2374–2383.
    • (2007) Diabetologia , vol.50 , Issue.11 , pp. 2374-2383
    • Cani, P.D.1    Neyrinck, A.M.2    Fava, F.3    Knauf, C.4    Burcelin, R.G.5    Tuohy, K.M.6
  • 19
  • 20
    • 67649443916 scopus 로고    scopus 로고
    • Probiotics and dietary counselling contribute to glucose regulation during and after pregnancy: a randomised controlled trial
    • Laitinen, K., Poussa, T., Isolauri, E., Probiotics and dietary counselling contribute to glucose regulation during and after pregnancy: a randomised controlled trial. Br J Nutr 101:11 (2009), 1679–1687.
    • (2009) Br J Nutr , vol.101 , Issue.11 , pp. 1679-1687
    • Laitinen, K.1    Poussa, T.2    Isolauri, E.3
  • 21
    • 78651076407 scopus 로고    scopus 로고
    • Health benefits of probiotics: are mixtures more effective than single strains?
    • Chapman, C.M., Gibson, G.R., Rowland, I., Health benefits of probiotics: are mixtures more effective than single strains?. Eur J Nutr 50:1 (2011), 1–17.
    • (2011) Eur J Nutr , vol.50 , Issue.1 , pp. 1-17
    • Chapman, C.M.1    Gibson, G.R.2    Rowland, I.3
  • 22
    • 85009911199 scopus 로고    scopus 로고
    • Genome-wide immune modulation of TLR3-mediated inflammation in intestinal epithelial cells differs between single and multi-strain probiotic combination
    • MacPherson, C.W., Shastri, P., Mathieu, O., Tompkins, T.A., Burguière, P., Genome-wide immune modulation of TLR3-mediated inflammation in intestinal epithelial cells differs between single and multi-strain probiotic combination. PLoS One, 12(1), 2017, e0169847.
    • (2017) PLoS One , vol.12 , Issue.1 , pp. e0169847
    • MacPherson, C.W.1    Shastri, P.2    Mathieu, O.3    Tompkins, T.A.4    Burguière, P.5
  • 23
    • 84893555765 scopus 로고    scopus 로고
    • Immune system stimulation by probiotic microorganisms
    • Ashraf, R., Shah, N.P., Immune system stimulation by probiotic microorganisms. Crit Rev Food Sci Nutr 54:7 (2014), 938–956.
    • (2014) Crit Rev Food Sci Nutr , vol.54 , Issue.7 , pp. 938-956
    • Ashraf, R.1    Shah, N.P.2
  • 24
    • 84899438179 scopus 로고    scopus 로고
    • In vivo gut transcriptome responses to lactobacillus rhamnosus GG and lactobacillus acidophilus in neonatal gnotobiotic piglets
    • Kumar, A., Vlasova, A.N., Liu, Z., Chattha, K.S., Kandasamy, S., Esseili, M., et al. In vivo gut transcriptome responses to lactobacillus rhamnosus GG and lactobacillus acidophilus in neonatal gnotobiotic piglets. Gut Microbes 5:2 (2014), 152–164.
    • (2014) Gut Microbes , vol.5 , Issue.2 , pp. 152-164
    • Kumar, A.1    Vlasova, A.N.2    Liu, Z.3    Chattha, K.S.4    Kandasamy, S.5    Esseili, M.6
  • 25
    • 77957927388 scopus 로고    scopus 로고
    • Effects of Bifidobacterium bifidum on adaptive immune senescence in aging mice
    • Fu, Y.R., Yi, Z.J., Pei, J.L., Guan, S., Effects of Bifidobacterium bifidum on adaptive immune senescence in aging mice. Microbiol Immunol 54:10 (2010), 578–583.
    • (2010) Microbiol Immunol , vol.54 , Issue.10 , pp. 578-583
    • Fu, Y.R.1    Yi, Z.J.2    Pei, J.L.3    Guan, S.4
  • 26
    • 84923316380 scopus 로고    scopus 로고
    • Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease
    • Hong, M., Kim, S.W., Han, S.H., Kim, D.J., Suk, K.T., Kim, Y.S., et al. Probiotics (Lactobacillus rhamnosus R0011 and acidophilus R0052) reduce the expression of toll-like receptor 4 in mice with alcoholic liver disease. PLoS One, 10(2), 2015, e0117451.
    • (2015) PLoS One , vol.10 , Issue.2 , pp. e0117451
    • Hong, M.1    Kim, S.W.2    Han, S.H.3    Kim, D.J.4    Suk, K.T.5    Kim, Y.S.6
  • 27
    • 84900346071 scopus 로고    scopus 로고
    • Lactobacillus rhamnosus GG protects against non-alcoholic fatty liver disease in mice
    • Ritze, Y., Bárdos, G., Claus, A., Ehrmann, V., Bergheim, I., Schwiertz, A., et al. Lactobacillus rhamnosus GG protects against non-alcoholic fatty liver disease in mice. PLoS One, 9(1), 2014, e80169.
    • (2014) PLoS One , vol.9 , Issue.1 , pp. e80169
    • Ritze, Y.1    Bárdos, G.2    Claus, A.3    Ehrmann, V.4    Bergheim, I.5    Schwiertz, A.6
  • 28
    • 84930005411 scopus 로고    scopus 로고
    • Effect of Lactobacillus rhamnosus hsryfm 1301 on the gut microbiota and lipid metabolism in rats fed a high-fat diet
    • Chen, D., Yang, Z., Chen, X., Huang, Y., Yin, B., Guo, F., et al. Effect of Lactobacillus rhamnosus hsryfm 1301 on the gut microbiota and lipid metabolism in rats fed a high-fat diet. J Microbiol Biotechnol 25:5 (2015), 687–695.
    • (2015) J Microbiol Biotechnol , vol.25 , Issue.5 , pp. 687-695
    • Chen, D.1    Yang, Z.2    Chen, X.3    Huang, Y.4    Yin, B.5    Guo, F.6
  • 29
    • 81855194317 scopus 로고    scopus 로고
    • The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication
    • Bercik, P., Park, A.J., Sinclair, D., Khoshdel, A., Lu, J., Huang, X., et al. The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication. Neurogastroenterol Motil 23:12 (2011), 1132–1139.
    • (2011) Neurogastroenterol Motil , vol.23 , Issue.12 , pp. 1132-1139
    • Bercik, P.1    Park, A.J.2    Sinclair, D.3    Khoshdel, A.4    Lu, J.5    Huang, X.6
  • 30
    • 80052965474 scopus 로고    scopus 로고
    • Ingestion of lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
    • Bravo, J.A., Forsythe, P., Chew, M.V., Escaravage, E., Savignac, H.M., Dinan, T.G., et al. Ingestion of lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proc Natl Acad Sci U S A 108:38 (2011), 16050–16055.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.38 , pp. 16050-16055
    • Bravo, J.A.1    Forsythe, P.2    Chew, M.V.3    Escaravage, E.4    Savignac, H.M.5    Dinan, T.G.6
  • 31
    • 84871260907 scopus 로고    scopus 로고
    • Brain–gut interactions in inflammatory bowel disease
    • Bonaz, B.L., Bernstein, C.N., Brain–gut interactions in inflammatory bowel disease. Gastroenterology 144:1 (2013), 36–49.
    • (2013) Gastroenterology , vol.144 , Issue.1 , pp. 36-49
    • Bonaz, B.L.1    Bernstein, C.N.2
  • 33
    • 84884696748 scopus 로고    scopus 로고
    • The gut microbiota reduces leptin sensitivity and the expression of the obesity-suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous system
    • Schele, E., Grahnemo, L., Anesten, F., Hallen, A., Backhed, F., Jansson, J.O., The gut microbiota reduces leptin sensitivity and the expression of the obesity-suppressing neuropeptides proglucagon (Gcg) and brain-derived neurotrophic factor (Bdnf) in the central nervous system. Endocrinology 154:10 (2013), 3643–3651.
    • (2013) Endocrinology , vol.154 , Issue.10 , pp. 3643-3651
    • Schele, E.1    Grahnemo, L.2    Anesten, F.3    Hallen, A.4    Backhed, F.5    Jansson, J.O.6
  • 34
    • 33744969137 scopus 로고    scopus 로고
    • Oligofructose promotes satiety in healthy human: a pilot study
    • Cani, P.D., Joly, E., Horsmans, Y., Delzenne, N.M., Oligofructose promotes satiety in healthy human: a pilot study. Eur J Clin Nutr 60:5 (2006), 567–572.
    • (2006) Eur J Clin Nutr , vol.60 , Issue.5 , pp. 567-572
    • Cani, P.D.1    Joly, E.2    Horsmans, Y.3    Delzenne, N.M.4
  • 35
    • 84975678760 scopus 로고    scopus 로고
    • How gut microbes talk to organs: the role of endocrine and nervous routes
    • Cani, P.D., Knauf, C., How gut microbes talk to organs: the role of endocrine and nervous routes. Mol Metab 5:9 (2016), 743–752.
    • (2016) Mol Metab , vol.5 , Issue.9 , pp. 743-752
    • Cani, P.D.1    Knauf, C.2
  • 36
    • 84867827691 scopus 로고    scopus 로고
    • Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice
    • Carvalho-Filho, M.A., Carvalho, B.M., Oliveira, A.G., Guadagnini, D., Ueno, M., Dias, M.M., et al. Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice. Endocrinology 153:11 (2012), 5261–5274.
    • (2012) Endocrinology , vol.153 , Issue.11 , pp. 5261-5274
    • Carvalho-Filho, M.A.1    Carvalho, B.M.2    Oliveira, A.G.3    Guadagnini, D.4    Ueno, M.5    Dias, M.M.6
  • 37
    • 35648937073 scopus 로고    scopus 로고
    • Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals
    • Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., Lebrasseur, N.K., et al. Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals. J Biol Chem 282:41 (2007), 30014–30021.
    • (2007) J Biol Chem , vol.282 , Issue.41 , pp. 30014-30021
    • Handschin, C.1    Chin, S.2    Li, P.3    Liu, F.4    Maratos-Flier, E.5    Lebrasseur, N.K.6
  • 38
    • 34147182303 scopus 로고    scopus 로고
    • A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria
    • Chakravorty, S., Helb, D., Burday, M., Connell, N., Alland, D., A detailed analysis of 16S ribosomal RNA gene segments for the diagnosis of pathogenic bacteria. J Microbiol Methods 69:2 (2007), 330–339.
    • (2007) J Microbiol Methods , vol.69 , Issue.2 , pp. 330-339
    • Chakravorty, S.1    Helb, D.2    Burday, M.3    Connell, N.4    Alland, D.5
  • 39
    • 39849107173 scopus 로고    scopus 로고
    • Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
    • Cintra, D.E., Pauli, J.R., Araujo, E.P., Moraes, J.C., de Souza, C.T., Milanski, M., et al. Interleukin-10 is a protective factor against diet-induced insulin resistance in liver. J Hepatol 48:4 (2008), 628–637.
    • (2008) J Hepatol , vol.48 , Issue.4 , pp. 628-637
    • Cintra, D.E.1    Pauli, J.R.2    Araujo, E.P.3    Moraes, J.C.4    de Souza, C.T.5    Milanski, M.6
  • 40
    • 84953347161 scopus 로고    scopus 로고
    • Pioglitazone treatment increases food intake and decreases energy expenditure partially via hypothalamic adiponectin/adipoR1/AMPK pathway
    • Quaresma, P.G., Reencober, N., Zanotto, T.M., Santos, A.C., Weissmann, L., de Matos, A.H., et al. Pioglitazone treatment increases food intake and decreases energy expenditure partially via hypothalamic adiponectin/adipoR1/AMPK pathway. Int J Obes (Lond) 40:1 (2016), 138–146.
    • (2016) Int J Obes (Lond) , vol.40 , Issue.1 , pp. 138-146
    • Quaresma, P.G.1    Reencober, N.2    Zanotto, T.M.3    Santos, A.C.4    Weissmann, L.5    de Matos, A.H.6
  • 41
    • 33745224043 scopus 로고    scopus 로고
    • Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle
    • Martin, T.L., Alquier, T., Asakura, K., Furukawa, N., Preitner, F., Kahn, B.B., Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. J Biol Chem 281:28 (2006), 18933–18941.
    • (2006) J Biol Chem , vol.281 , Issue.28 , pp. 18933-18941
    • Martin, T.L.1    Alquier, T.2    Asakura, K.3    Furukawa, N.4    Preitner, F.5    Kahn, B.B.6
  • 42
    • 84865477413 scopus 로고    scopus 로고
    • Antibiotics in early life alter the murine colonic microbiome and adiposity
    • Cho, I., Yamanishi, S., Cox, L., Methe, B.A., Zavadil, J., Li, K., et al. Antibiotics in early life alter the murine colonic microbiome and adiposity. Nature 488:7413 (2012), 621–626.
    • (2012) Nature , vol.488 , Issue.7413 , pp. 621-626
    • Cho, I.1    Yamanishi, S.2    Cox, L.3    Methe, B.A.4    Zavadil, J.5    Li, K.6
  • 43
    • 84919449455 scopus 로고    scopus 로고
    • Intestinal colonization by a Lachnospiraceae bacterium contributes to the development of diabetes in obese mice
    • Kameyama, K., Itoh, K., Intestinal colonization by a Lachnospiraceae bacterium contributes to the development of diabetes in obese mice. Microbes Environ 29:4 (2014), 427–430.
    • (2014) Microbes Environ , vol.29 , Issue.4 , pp. 427-430
    • Kameyama, K.1    Itoh, K.2
  • 44
    • 84867074831 scopus 로고    scopus 로고
    • A metagenome-wide association study of gut microbiota in type 2 diabetes
    • Qin, J., Li, Y., Cai, Z., Li, S., Zhu, J., Zhang, F., et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490:7418 (2012), 55–60.
    • (2012) Nature , vol.490 , Issue.7418 , pp. 55-60
    • Qin, J.1    Li, Y.2    Cai, Z.3    Li, S.4    Zhu, J.5    Zhang, F.6
  • 45
    • 79951683913 scopus 로고    scopus 로고
    • Obesity, diabetes, and gut microbiota: the hygiene hypothesis expanded?
    • Musso, G., Gambino, R., Cassader, M., Obesity, diabetes, and gut microbiota: the hygiene hypothesis expanded?. Diabetes Care 33:10 (2010), 2277–2284.
    • (2010) Diabetes Care , vol.33 , Issue.10 , pp. 2277-2284
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 46
    • 53849104768 scopus 로고    scopus 로고
    • Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women
    • Collado, M.C., Isolauri, E., Laitinen, K., Salminen, S., Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. Am J Clin Nutr 88:4 (2008), 894–899.
    • (2008) Am J Clin Nutr , vol.88 , Issue.4 , pp. 894-899
    • Collado, M.C.1    Isolauri, E.2    Laitinen, K.3    Salminen, S.4
  • 48
    • 84856957894 scopus 로고    scopus 로고
    • Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
    • Henao-Mejia, J., Elinav, E., Jin, C., Hao, L., Mehal, W.Z., Strowig, T., et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 482:7384 (2012), 179–185.
    • (2012) Nature , vol.482 , Issue.7384 , pp. 179-185
    • Henao-Mejia, J.1    Elinav, E.2    Jin, C.3    Hao, L.4    Mehal, W.Z.5    Strowig, T.6
  • 50
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round, J.L., Mazmanian, S.K., The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9:5 (2009), 313–323.
    • (2009) Nat Rev Immunol , vol.9 , Issue.5 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 51
    • 67149141502 scopus 로고    scopus 로고
    • Diet-induced metabolic improvements in a hamster model of hypercholesterolemia are strongly linked to alterations of the gut microbiota
    • Martinez, I., Wallace, G., Zhang, C., Legge, R., Benson, A.K., Carr, T.P., et al. Diet-induced metabolic improvements in a hamster model of hypercholesterolemia are strongly linked to alterations of the gut microbiota. Appl Environ Microbiol 75:12 (2009), 4175–4184.
    • (2009) Appl Environ Microbiol , vol.75 , Issue.12 , pp. 4175-4184
    • Martinez, I.1    Wallace, G.2    Zhang, C.3    Legge, R.4    Benson, A.K.5    Carr, T.P.6
  • 52
    • 84857729398 scopus 로고    scopus 로고
    • Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota
    • Serino, M., Luche, E., Gres, S., Baylac, A., Berge, M., Cenac, C., et al. Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut 61:4 (2012), 543–553.
    • (2012) Gut , vol.61 , Issue.4 , pp. 543-553
    • Serino, M.1    Luche, E.2    Gres, S.3    Baylac, A.4    Berge, M.5    Cenac, C.6
  • 53
    • 0038491435 scopus 로고    scopus 로고
    • Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation
    • Le Poul, E., Loison, C., Struyf, S., Springael, J.Y., Lannoy, V., Decobecq, M.E., et al. Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem 278:28 (2003), 25481–25489.
    • (2003) J Biol Chem , vol.278 , Issue.28 , pp. 25481-25489
    • Le Poul, E.1    Loison, C.2    Struyf, S.3    Springael, J.Y.4    Lannoy, V.5    Decobecq, M.E.6
  • 54
    • 77950221874 scopus 로고    scopus 로고
    • Glucagon and glucagon-like peptides 1 and 2
    • Holst, J.J., Glucagon and glucagon-like peptides 1 and 2. Results Probl Cell Differ 50 (2010), 121–135.
    • (2010) Results Probl Cell Differ , vol.50 , pp. 121-135
    • Holst, J.J.1
  • 55
    • 84857282231 scopus 로고    scopus 로고
    • Toll-like receptor-gut microbiota interactions: perturb at your own risk!
    • Carvalho, F.A., Aitken, J.D., Vijay-Kumar, M., Gewirtz, A.T., Toll-like receptor-gut microbiota interactions: perturb at your own risk!. Annu Rev Physiol 74 (2012), 177–198.
    • (2012) Annu Rev Physiol , vol.74 , pp. 177-198
    • Carvalho, F.A.1    Aitken, J.D.2    Vijay-Kumar, M.3    Gewirtz, A.T.4
  • 56
    • 0030669392 scopus 로고    scopus 로고
    • A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
    • Paz, K., Hemi, R., LeRoith, D., Karasik, A., Elhanany, E., Kanety, H., et al. A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation. J Biol Chem 272:47 (1997), 29911–29918.
    • (1997) J Biol Chem , vol.272 , Issue.47 , pp. 29911-29918
    • Paz, K.1    Hemi, R.2    LeRoith, D.3    Karasik, A.4    Elhanany, E.5    Kanety, H.6
  • 57
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil, G.S., Peraldi, P., Budavari, A., Ellis, R., White, M.F., Spiegelman, B.M., IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:5249 (1996), 665–668.
    • (1996) Science , vol.271 , Issue.5249 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 58
    • 33745861300 scopus 로고    scopus 로고
    • Inflammation and insulin resistance
    • Shoelson, S.E., Lee, J., Goldfine, A.B., Inflammation and insulin resistance. J Clin Invest 116:7 (2006), 1793–1801.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 1793-1801
    • Shoelson, S.E.1    Lee, J.2    Goldfine, A.B.3
  • 60
    • 34250904186 scopus 로고    scopus 로고
    • Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
    • Furuhashi, M., Tuncman, G., Gorgun, C.Z., Makowski, L., Atsumi, G., Vaillancourt, E., et al. Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 447:7147 (2007), 959–965.
    • (2007) Nature , vol.447 , Issue.7147 , pp. 959-965
    • Furuhashi, M.1    Tuncman, G.2    Gorgun, C.Z.3    Makowski, L.4    Atsumi, G.5    Vaillancourt, E.6
  • 61
    • 33748111665 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin resistance
    • Tilg, H., Hotamisligil, G.S., Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 131:3 (2006), 934–945.
    • (2006) Gastroenterology , vol.131 , Issue.3 , pp. 934-945
    • Tilg, H.1    Hotamisligil, G.S.2
  • 62
    • 84901006228 scopus 로고    scopus 로고
    • Neurobiology of food intake in health and disease
    • Morton, G.J., Meek, T.H., Schwartz, M.W., Neurobiology of food intake in health and disease. Nat Rev Neurosci 15:6 (2014), 367–378.
    • (2014) Nat Rev Neurosci , vol.15 , Issue.6 , pp. 367-378
    • Morton, G.J.1    Meek, T.H.2    Schwartz, M.W.3
  • 63
    • 78649466467 scopus 로고    scopus 로고
    • CNS leptin and insulin action in the control of energy homeostasis
    • Belgardt, B.F., Bruning, J.C., CNS leptin and insulin action in the control of energy homeostasis. Ann N Y Acad Sci 1212 (2010), 97–113.
    • (2010) Ann N Y Acad Sci , vol.1212 , pp. 97-113
    • Belgardt, B.F.1    Bruning, J.C.2
  • 64
    • 78049311283 scopus 로고    scopus 로고
    • Obesity and leptin resistance: distinguishing cause from effect
    • Myers, M.G. Jr., Leibel, R.L., Seeley, R.J., Schwartz, M.W., Obesity and leptin resistance: distinguishing cause from effect. Trends Endocrinol Metab 21:11 (2010), 643–651.
    • (2010) Trends Endocrinol Metab , vol.21 , Issue.11 , pp. 643-651
    • Myers, M.G.1    Leibel, R.L.2    Seeley, R.J.3    Schwartz, M.W.4
  • 65
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi, H., Kokoeva, M.V., Inouye, K., Tzameli, I., Yin, H., Flier, J.S., TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116:11 (2006), 3015–3025.
    • (2006) J Clin Invest , vol.116 , Issue.11 , pp. 3015-3025
    • Shi, H.1    Kokoeva, M.V.2    Inouye, K.3    Tzameli, I.4    Yin, H.5    Flier, J.S.6
  • 66
    • 84879139320 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor in the brain: role in neuroendocrine control of energy metabolism and treatment target for obesity
    • Lockie, S.H., Glucagon-like peptide-1 receptor in the brain: role in neuroendocrine control of energy metabolism and treatment target for obesity. J Neuroendocrinol 25:7 (2013), 597–604.
    • (2013) J Neuroendocrinol , vol.25 , Issue.7 , pp. 597-604
    • Lockie, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.