-
1
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
Turnbaugh PJ, Hamady M, Yatsunenko T, et al. A core gut microbiome in obese and lean twins. Nature 2009; 457:480-484.
-
(2009)
Nature
, vol.457
, pp. 480-484
-
-
Turnbaugh, P.J.1
Hamady, M.2
Yatsunenko, T.3
-
2
-
-
84883110880
-
Richness of human gut microbiome correlates with metabolic markers
-
Le Chatelier E, Nielsen T, Qin J, et al. Richness of human gut microbiome correlates with metabolic markers. Nature 2013; 500:541-546.
-
(2013)
Nature
, vol.500
, pp. 541-546
-
-
Le Chatelier, E.1
Nielsen, T.2
Qin, J.3
-
3
-
-
84883478660
-
Gut microbiota from twins discordant for obesity modulate metabolism in mice
-
Ridaura VK, Faith JJ, Rey FE, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013; 341:1241214.
-
(2013)
Science
, vol.341
, pp. 1241214
-
-
Ridaura, V.K.1
Faith, J.J.2
Rey, F.E.3
-
4
-
-
77649086402
-
Immune adaptations that maintain homeostasis with the intestinal microbiota
-
Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol 2010; 10:159-169.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 159-169
-
-
Hooper, L.V.1
MacPherson, A.J.2
-
5
-
-
79952748287
-
Unravelling the effects of the environment and host genotype on the gut microbiome
-
Spor A, Koren O, Ley R. Unravelling the effects of the environment and host genotype on the gut microbiome. Nat Rev Microbiol 2011; 9:279-290.
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 279-290
-
-
Spor, A.1
Koren, O.2
Ley, R.3
-
6
-
-
78049337953
-
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
-
Speliotes EK, Willer CJ, Berndt SI, et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010; 42:937-948.
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
-
7
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
Frayling TM, Timpson NJ, Weedon MN, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316:889-894.
-
(2007)
Science
, vol.316
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
-
8
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos RJ, LindgrenCM, Li S, et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40:768-775.
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgrencm Li, S.2
-
9
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Willer CJ, Speliotes EK, Loos RJ, et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009; 41:25-34.
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
-
10
-
-
58149163141
-
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity
-
Thorleifsson G, Walters GB, Gudbjartsson DF, et al. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 2009; 41:18-24.
-
(2009)
Nat Genet
, vol.41
, pp. 18-24
-
-
Thorleifsson, G.1
Walters, G.B.2
Gudbjartsson, D.F.3
-
11
-
-
78049349396
-
Meta-Analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
-
Heid IM, Jackson AU, Randall JC, et al. Meta-Analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010; 42:949-960.
-
(2010)
Nat Genet
, vol.42
, pp. 949-960
-
-
Heid, I.M.1
Jackson, A.U.2
Randall, J.C.3
-
12
-
-
67651236725
-
Genome-wide association scan meta-Analysis identifies three Loci influencing adiposity and fat distribution
-
Lindgren CM, Heid IM, Randall JC, et al. Genome-wide association scan meta-Analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009; 5:e1000508.
-
(2009)
PLoS Genet
, vol.5
-
-
Lindgren, C.M.1
Heid, I.M.2
Randall, J.C.3
-
13
-
-
33845901507
-
Microbial ecology: Human gut microbes associated with obesity
-
Ley RE, Turnbaugh PJ, Klein S, et al. Microbial ecology: human gut microbes associated with obesity. Nature 2006; 444:1022-1023.
-
(2006)
Nature
, vol.444
, pp. 1022-1023
-
-
Ley, R.E.1
Turnbaugh, P.J.2
Klein, S.3
-
14
-
-
78650037263
-
Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: Links with metabolic and low-grade inflammation markers
-
Furet JP, Kong LC, Tap J, et al. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes 2010; 59:3049-3057.
-
(2010)
Diabetes
, vol.59
, pp. 3049-3057
-
-
Furet, J.P.1
Kong, L.C.2
Tap, J.3
-
15
-
-
73949137604
-
Microbiota and SCFA in lean and overweight healthy subjects
-
Schwiertz A, Taras D, Schafer K, et al. Microbiota and SCFA in lean and overweight healthy subjects. Obesity 2010; 18:190-195.
-
(2010)
Obesity
, vol.18
, pp. 190-195
-
-
Schwiertz, A.1
Taras, D.2
Schafer, K.3
-
16
-
-
41849127118
-
Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
-
Turnbaugh PJ, Backhed F, Fulton L, et al. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 2008; 3:213-223.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 213-223
-
-
Turnbaugh, P.J.1
Backhed, F.2
Fulton, L.3
-
17
-
-
84892828465
-
Diet rapidly and reproducibly alters the human gut microbiome
-
David LA, Maurice CF, Carmody RN, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 2014; 505:559-563.
-
(2014)
Nature
, vol.505
, pp. 559-563
-
-
David, L.A.1
Maurice, C.F.2
Carmody, R.N.3
-
18
-
-
84860441011
-
Inflammation and lipid signaling in the etiology of insulin resistance
-
Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab 2012; 15:635-645.
-
(2012)
Cell Metab
, vol.15
, pp. 635-645
-
-
Glass, C.K.1
Olefsky, J.M.2
-
19
-
-
84883057637
-
Dietary intervention impact on gut microbial gene richness
-
Cotillard A, Kennedy SP, Kong LC, et al. Dietary intervention impact on gut microbial gene richness. Nature 2013; 500:585-588.
-
(2013)
Nature
, vol.500
, pp. 585-588
-
-
Cotillard, A.1
Kennedy, S.P.2
Kong, L.C.3
-
20
-
-
77956060045
-
Obesity, metabolic syndrome, and microbiota: Multiple interactions
-
Tilg H. Obesity, metabolic syndrome, and microbiota: multiple interactions. J Clin Gastroenterol 2010; 44 (Suppl 1):S16-S18.
-
(2010)
J Clin Gastroenterol
, vol.44 SUPPL 1
-
-
Tilg, H.1
-
21
-
-
77950669604
-
The effect of diet on the human gut microbiome: A metagenomic analysis in humanized gnotobiotic mice
-
Turnbaugh PJ, Ridaura VK, Faith JJ, et al. The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 2009; 1:6-14.
-
(2009)
Sci Transl Med
, pp. 16-14
-
-
Turnbaugh, P.J.1
Ridaura, V.K.2
Faith, J.J.3
-
22
-
-
33847233644
-
Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
-
Duncan SH, Belenguer A, Holtrop G, et al. Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Appl Environ Microbiol 2007; 73:1073-1078.
-
(2007)
Appl Environ Microbiol
, vol.73
, pp. 1073-1078
-
-
Duncan, S.H.1
Belenguer, A.2
Holtrop, G.3
-
23
-
-
55949124035
-
Faecalibacterium prausnitzii is an antiinflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
-
Sokol H, Pigneur B, Watterlot L, et al. Faecalibacterium prausnitzii is an antiinflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2008; 105:16731-16736.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16731-16736
-
-
Sokol, H.1
Pigneur, B.2
Watterlot, L.3
-
24
-
-
33947124087
-
Metabolism of linoleic acid by human gut bacteria: Different routes for biosynthesis of conjugated linoleic acid
-
Devillard E, McIntosh FM, Duncan SH, et al. Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid. J Bacteriol 2007; 189:2566-2570.
-
(2007)
J Bacteriol
, vol.189
, pp. 2566-2570
-
-
Devillard, E.1
McIntosh, F.M.2
Duncan, S.H.3
-
25
-
-
78149283854
-
Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria
-
Png CW, Linden SK, Gilshenan KS, et al. Mucolytic bacteria with increased prevalence in IBD mucosa augment in vitro utilization of mucin by other bacteria. Am J Gastroenterol 2010; 105:2420-2428.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 2420-2428
-
-
Png, C.W.1
Linden, S.K.2
Gilshenan, K.S.3
-
26
-
-
79953748870
-
Dysbiosis of the faecal microbiota in patients with Crohns disease and their unaffected relatives
-
Joossens M, Huys G, Cnockaert M, et al. Dysbiosis of the faecal microbiota in patients with Crohns disease and their unaffected relatives. Gut 2011; 60:631-637.
-
(2011)
Gut
, vol.60
, pp. 631-637
-
-
Joossens, M.1
Huys, G.2
Cnockaert, M.3
-
27
-
-
34247104503
-
An emerging synthesis between community ecology and evolutionary biology
-
Johnson MT, Stinchcombe JR. An emerging synthesis between community ecology and evolutionary biology. Trends Ecol Evol 2007; 22:250-257.
-
(2007)
Trends Ecol Evol
, vol.22
, pp. 250-257
-
-
Johnson, M.T.1
Stinchcombe, J.R.2
-
28
-
-
70350666634
-
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
-
Maslowski KM, Vieira AT, Ng A, et al. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 2009; 461:1282-1286.
-
(2009)
Nature
, vol.461
, pp. 1282-1286
-
-
Maslowski, K.M.1
Vieira, A.T.2
Ng, A.3
-
29
-
-
84890550163
-
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
-
Arpaia N, Campbell C, Fan X, et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature 2013; 504:451-455.
-
(2013)
Nature
, vol.504
, pp. 451-455
-
-
Arpaia, N.1
Campbell, C.2
Fan, X.3
-
30
-
-
84881068658
-
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
-
Smith PM, Howitt MR, Panikov N, et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 2013; 341:569-573.
-
(2013)
Science
, vol.341
, pp. 569-573
-
-
Smith, P.M.1
Howitt, M.R.2
Panikov, N.3
-
31
-
-
84893859801
-
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
-
Chang PV, Hao L, Offermanns S, et al. The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc Natl Acad Sci US A 2014; 111:2247-2252.
-
(2014)
Proc Natl Acad Sci US A
, vol.111
, pp. 2247-2252
-
-
Chang, P.V.1
Hao, L.2
Offermanns, S.3
-
32
-
-
84855174006
-
Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice
-
Caricilli AM, Picardi PK, de Abreu LL, et al. Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice. PLoS Biol 2011; 9:e1001212.
-
(2011)
PLoS Biol
, vol.9
-
-
Caricilli, A.M.1
Picardi, P.K.2
De Abreu, L.L.3
-
33
-
-
33845874101
-
An obesity-Associated gut microbiome with increased capacity for energy harvest
-
Turnbaugh PJ, Ley RE, Mahowald MA, et al. An obesity-Associated gut microbiome with increased capacity for energy harvest. Nature 2006; 444:1027-1031.
-
(2006)
Nature
, vol.444
, pp. 1027-1031
-
-
Turnbaugh, P.J.1
Ley, R.E.2
Mahowald, M.A.3
-
34
-
-
79953653547
-
Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse
-
Kuo LH, Tsai PJ, Jiang MJ, et al. Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse. Diabetologia 2011; 54:168-179.
-
(2011)
Diabetologia
, vol.54
, pp. 168-179
-
-
Kuo, L.H.1
Tsai, P.J.2
Jiang, M.J.3
-
35
-
-
77952315676
-
Tlr2 is critical for diet-induced metabolic syndrome in a murine model
-
Himes RW, Smith CW. Tlr2 is critical for diet-induced metabolic syndrome in a murine model. FASEB J 2010; 24:731-739.
-
(2010)
FASEB J
, vol.24
, pp. 731-739
-
-
Himes, R.W.1
Smith, C.W.2
-
36
-
-
79955664245
-
Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice
-
Kellermayer R, Dowd SE, Harris RA, et al. Colonic mucosal DNA methylation, immune response, and microbiome patterns in Toll-like receptor 2-knockout mice. FASEB J 2011; 25:1449-1460.
-
(2011)
FASEB J
, vol.25
, pp. 1449-1460
-
-
Kellermayer, R.1
Dowd, S.E.2
Harris, R.A.3
-
37
-
-
34347399563
-
Metabolic endotoxemia initiates obesity and insulin resistance
-
Cani PD, Amar J, Iglesias MA, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007; 56:1761-1772.
-
(2007)
Diabetes
, vol.56
, pp. 1761-1772
-
-
Cani, P.D.1
Amar, J.2
Iglesias, M.A.3
-
38
-
-
84866141702
-
Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice
-
Carvalho BM, Guadagnini D, Tsukumo DM, et al. Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice. Diabetologia 2012; 55:2823-2834.
-
(2012)
Diabetologia
, vol.55
, pp. 2823-2834
-
-
Carvalho, B.M.1
Guadagnini, D.2
Tsukumo, D.M.3
-
39
-
-
77950250064
-
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
-
Vijay-Kumar M, Aitken JD, Carvalho FA, et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010; 328:228-231.
-
(2010)
Science
, vol.328
, pp. 228-231
-
-
Vijay-Kumar, M.1
Aitken, J.D.2
Carvalho, F.A.3
-
40
-
-
79955890870
-
Bile acid metabolism and the pathogenesis of type 2 diabetes
-
Prawitt J, Caron S, Staels B. Bile acid metabolism and the pathogenesis of type 2 diabetes. Curr Diab Rep 2011; 11:160-166.
-
(2011)
Curr Diab Rep
, vol.11
, pp. 160-166
-
-
Prawitt, J.1
Caron, S.2
Staels, B.3
-
41
-
-
79959525960
-
The bile acid membrane receptor TGR5: A valuable metabolic target
-
Pols TW, Noriega LG, Nomura M, et al. The bile acid membrane receptor TGR5: a valuable metabolic target. Dig Dis 2011; 29:37-44.
-
(2011)
Dig Dis
, vol.29
, pp. 37-44
-
-
Pols, T.W.1
Noriega, L.G.2
Nomura, M.3
-
42
-
-
34248152283
-
Long-Term ecological impacts of antibiotic administration on the human intestinal microbiota
-
Jernberg C, Lofmark S, Edlund C, et al. Long-Term ecological impacts of antibiotic administration on the human intestinal microbiota. ISME J 2007; 1:56-66.
-
(2007)
ISME J
, vol.1
, pp. 56-66
-
-
Jernberg, C.1
Lofmark, S.2
Edlund, C.3
-
43
-
-
84872112919
-
Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity
-
Murphy EF, Cotter PD, Hogan A, et al. Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity. Gut 2013; 62:220-226.
-
(2013)
Gut
, vol.62
, pp. 220-226
-
-
Murphy, E.F.1
Cotter, P.D.2
Hogan, A.3
-
44
-
-
77949363140
-
Vancomycin treatment of infective endocarditis is linked with recently acquired obesity
-
Thuny F, Richet H, Casalta JP, et al. Vancomycin treatment of infective endocarditis is linked with recently acquired obesity. PloS One 2010; 5:e9074.
-
(2010)
PloS One
, vol.5
-
-
Thuny, F.1
Richet, H.2
Casalta, J.P.3
-
45
-
-
84896401262
-
Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity
-
Vrieze A,Out C, Fuentes S, et al. Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity. J Hepatol 2014; 60:825-831.
-
(2014)
J Hepatol
, vol.60
, pp. 825-831
-
-
Vrieze Aout, C.1
Fuentes, S.2
|