Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice

Diabetologia

Volumn 55, Issue 10, 2012, Pages 2823-2834

  Carvalho, B M ^a   Guadagnini, D ^a   Tsukumo, D M L ^a   Schenka, A A ^a   Latuf Filho, P ^a   Vassallo, J ^a   Dias, J C ^a   Kubota, L T ^a   Carvalheira, J B C ^a   Saad, M J A ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Gut microbiota; High fat diet; Inflammation; Insulin resistance; Lipopolysaccharide

Indexed keywords

ACETIC ACID; AMPICILLIN; ANTIBIOTIC AGENT; DNA; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; I KAPPA B KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LIVER PROTEIN; METRONIDAZOLE; MUSCLE PROTEIN; NEOMYCIN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BACTERIAL COUNT; BACTEROIDETES; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; FECES; FIRMICUTES; GENETIC ANALYSIS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; INTESTINE FLORA; LIPID DIET; LIVER; MACROPHAGE; MALE; METAGENOME; MODULATION; MOUSE; MUSCLE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACETATES; ANIMALS; ANTI-BACTERIAL AGENTS; BACTEROIDES; CELL MOVEMENT; CYTOKINES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; GASTROINTESTINAL TRACT; INSULIN; INSULIN RESISTANCE; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; METAGENOME; MICE; OBESITY; PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 84866141702     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2648-4     Document Type: Article

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