The impact of irreproducibility and competing protection from P2Y12 antagonists on the discovery of cardioprotective interventions

Basic Research in Cardiology

Volumn 112, Issue 6, 2017, Pages

  Cohen, Michael V ^a   Downey, James M ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cardioprotection; P2Y12 antagonists; Postconditioning; Preconditioning; Reperfusion injury

Indexed keywords

CANGRELOR; CLOPIDOGREL; PRASUGREL; PURINERGIC P2Y RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR ANTAGONIST; TICAGRELOR; UNCLASSIFIED DRUG; CARDIOTONIC AGENT; PURINERGIC P2Y12 RECEPTOR;

ACUTE HEART INFARCTION; HEART INFARCTION SIZE; HEART PROTECTION; HUMAN; ISCHEMIC POSTCONDITIONING; ISCHEMIC PRECONDITIONING; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; NONHUMAN; PERCUTANEOUS CORONARY INTERVENTION; REVIEW; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; ANIMAL; CLINICAL TRIAL (TOPIC); HEART INFARCTION; METHODOLOGY; PROCEDURES; REPRODUCIBILITY; STANDARDS;

ANIMALS; CARDIOTONIC AGENTS; CLINICAL TRIALS AS TOPIC; HUMANS; MYOCARDIAL INFARCTION; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y12; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN;

EID: 85029955867     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-017-0653-y     Document Type: Review

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