Maternal Inflammation Results in Altered Tryptophan Metabolism in Rabbit Placenta and Fetal Brain

Developmental Neuroscience

Volumn 39, Issue 5, 2017, Pages 399-412

  Williams, Monica ^a   Zhang, Zhi ^a   Nance, Elizabeth ^a   Drewes, Julia L ^a   Lesniak, Wojciech G ^b   Singh, Sarabdeep ^a   Chugani, Diane C ^c,d   Rangaramanujam, Kannan ^b   Graham, David R ^a   Kannan, Sujatha ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^d UNIVERSITY OF DELAWARE   (United States)

Author keywords

Autism; Cerebral palsy; Kynurenine pathway; Maternal infection; Microglia; Serotonin; Tryptophan

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; AMINOTRANSFERASE; ENDOTOXIN; GAMMA INTERFERON; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; KYNURENINE 3 MONOOXYGENASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; QUINOLINIC ACID; SEROTONIN; TRYPTOPHAN; 5-HYDROXYINDOLE; INDOLE DERIVATIVE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL COUNT; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FETUS; FETUS BRAIN; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEPORIDAE; MACROPHAGE; MASS FRAGMENTOGRAPHY; MATERNAL DISEASE; MICROGLIA; NONHUMAN; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRYPTOPHAN METABOLISM; UPREGULATION; ANIMAL; BRAIN; CHEMICALLY INDUCED; EMBRYOLOGY; FEMALE; METABOLISM; PREGNANCY;

ANIMALS; BRAIN; FEMALE; INDOLES; INFLAMMATION; PLACENTA; PREGNANCY; QUINOLINIC ACID; RABBITS; SEROTONIN; TRYPTOPHAN;

EID: 85029818347     PISSN: 03785866     EISSN: 14219859     Source Type: Journal    
DOI: 10.1159/000471509     Document Type: Article

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