Neuroprotective effect of excitatory amino acid antagonist kynurenic acid in experimental bacterial meningitis

Journal of Infectious Diseases

Volumn 173, Issue 1, 1996, Pages 166-171

  Leib, Stephen L ^b   Kim, Young S ^b   Ferriero, Donna M ^b   Täuber, Martin G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; EXCITATORY AMINO ACID; EXCITATORY AMINO ACID RECEPTOR; GLUTAMIC ACID; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL MENINGITIS; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; HIPPOCAMPUS; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN INFECTION; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOCOCCUS AGALACTIAE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030059740     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.1.166     Document Type: Article

References (27)

1. Durand MI, Calderwood SB, Weber DJ, et al. Acute bacterial meningitis in adults: a review of 493 episodes. N Engl J Med 1993;328:21-8.
2. Franco SM, Cornelius VE, Andrews BF. Long-term outcome of neonatal meningitis. Am J Dis Child 1992;146:567-71.
3. Edwards MS, Rench MA, Haffar AAM, Murphy MA, Desmond MM, Baker CJ. Long-term sequelae of group B streptococcal meningitis in infants. J Pediatr 1985;106:717-22.
4. Kim YS, Sheldon RA, Elliot BR, Liu Q, Ferriero DM, Täuber MG. Brain damage in neonatal meningitis caused by group B streptococci in rats. J Neuropathol Exp Neurol 1995;54:531-9.
5. Berman PH, Banker BQ. Neonatal meningitis. A clinical and pathological study of 29 cases. Pediatrics 1966;38:6-24.
6. Guerra-Romero L, Tureen JH, Founrier MA, Makrides V, Täuber MG. Amino acids in cerebrospinal and brain interstitial fluid during experimental pneumococcal meningitis. Pediatr Res 1993;33:510-3.
7. Perry V, Young RSK, Aquilla WJ, During MJ. Effect of experimental Escherichia coli meningitis on concentrations of excitatory and inhibitory amino acids in the rabbit brain: in vivo microdialysis study. Pediatr Res 1993;34:187-91.
8. Espanol MT, Xu Y, Litt L, et al. Modulation of glutamate-induced intracellular energy failure in neonatal cerebral cortical slices by kynurenic acid, dizocilpine, and NBQX. J Cereb Blood Flow Metabol 1994;14:269-78.
9. Simon RP, Young RSK, Stout S, Cheng J. Inhibition of excitatory neurotransmission with kynurinate reduces brain edema in neonatal anoxia. Neurosci Lett 1986;71:361-4.
10. Smith DH, Okiyama KO, Thomas MJ, McIntosh TM. Effects of the excitatory arnino acid receptor antagonists kynurenate and indole-2-carcoxylic acid on behavioral and neurochemical outcome following experimental brain injury. J Neurosci 1993;13:5383-92.
11. Ferriero DM, Sagar SM, Arcavi LJ, McIntosh TK, Simon RP. Selective sparing of NADPH diaphorase neurons in neonatal hypoxia-ischemia. Ann Neurol 1988;24:670-7.
12. Monaghan DT, Bridges RJ, Cotman CW. The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu Rev Pharmacol Toxicol 1989;29:365-402.
13. McDonald JW, Johnston MV. Physiological and pathophysiological roles of excitatory amino acids during central nervous development. Brain Res Rev 1990;15:41-70.
14. Choi DW. Excitotoxic cell death. J Neurobiol 1992;23:1261-76.
15. Stone TW. Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 1993;45:309-79.
16. San Joaquin V, Khai N, Seaale T, Rennert O. Increased cerebrospinal fluid free amino acid concentrations in children with bacterial meningitis. Scand J Infect Dis 1982;14:23-6.
17. Segal MB, Zlokovic BV. The blood-brain barrier, amino acids, and peptides. Boston: Kluver Academic Publishers, 1990:31-45.
18. Auer RN, Siesjö BK. Biological differences between ischemia, hypoglycemia, and epilepsy. Ann Neurol 1988;24:699-707.
19. Giulian D, Vaca K, Copuz M. Brain glia release factors with opposing actions upon neuronal survival. J Neurosci 1993;13:29-37.
20. Eddleston M, Mucke L. Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience 1993;54:15-36.
21. Smith JF, Landing BH. Mechanisms of brain damage in H. influenzae meningitis. J Neuropathol Exp Neurol 1960;19:248-65.
22. Förderreuther S, Tatsch K, Einhäupl KM, Pfister HW. Abnormalities of cerebral blood flow in the acute phase of bacterial meningitis in adults. J Neurol 1992;239:431-6.
23. Pfister HW, Borasio GD, Dirnagl U, Bauer M, Einhäupl KM. Cerebrovascular complications of bacterial meningitis in adults. Neurology 1992;42:1497-504.
24. Tureen JH, Dworkin RJ, Kennedy SL, Sachdeva M, Sande MA. Loss of cerebrovascular autoregulation in experimental meningitis in rabbits. J Clin Invest 1990;85:577-81.
25. Täuber MG, Burroughs M, Niemöller UM, Kuster H, Borschberg U, Tuomanen E. Differences of pathophysiology in experimental meningitis caused by three strains of Streptococcus pneumoniae. J Infect Dis 1991;163:806-11.
26. Tureen JH, Täuber MG, Sande MA. Effect of hydration status on cerebral blood flow and cerebrospinal fluid lactic acidosis in rabbits with experimental meningitis. J Clin Invest 1992;89:947-53.
27. Cataltepe O, Vannucci D, Heitjan D, Towfighi J. Effect of status epilepticus on hypoxic-ischemic brain damage in the immature rat. Pediatr Res 1995;38:251-7.