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Volumn 55, Issue 13, 2007, Pages 1385-1396

IFN-γ-induced IDO and WRS expression in microglia is differentially regulated by IL-4

Author keywords

Cytokine; Indoleamine 2,3 dioxygenase; Tryptophanyl tRNA synthetase

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 13; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE 2A; STAT1 PROTEIN; STAT6 PROTEIN; TRYPTOPHAN TRANSFER RNA LIGASE;

EID: 34548211823     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20544     Document Type: Article
Times cited : (53)

References (60)
  • 1
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed NN, Grimes HL, Bellacosa A, Chan TO, Tsichlis PN. 1997. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc Natl Acad Sci USA 94:3627-3632.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3627-3632
    • Ahmed, N.N.1    Grimes, H.L.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 2
    • 0030889207 scopus 로고    scopus 로고
    • The IFN γ receptor: A paradigm for cytokine receptor signaling
    • Bach EA, Aguet M, Schreiber RD. 1997. The IFN γ receptor: A paradigm for cytokine receptor signaling. Annu Rev Immunol 15:563-591.
    • (1997) Annu Rev Immunol , vol.15 , pp. 563-591
    • Bach, E.A.1    Aguet, M.2    Schreiber, R.D.3
  • 4
    • 0023691731 scopus 로고
    • Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics
    • Bialojan C, Takai A. 1988. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics Biochem J 256:283-290.
    • (1988) Biochem J , vol.256 , pp. 283-290
    • Bialojan, C.1    Takai, A.2
  • 5
    • 85117737982 scopus 로고    scopus 로고
    • Boasso A, Herbeuval JP, Hardy AW, Winkler C, Shearer GM. 2005. Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells. Blood 105-1574-1581.
    • Boasso A, Herbeuval JP, Hardy AW, Winkler C, Shearer GM. 2005. Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells. Blood 105-1574-1581.
  • 6
    • 27144476792 scopus 로고    scopus 로고
    • A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation
    • Braun D, Longman RS, Albert ML. 2005. A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation. Blood 106:2375-2381.
    • (2005) Blood , vol.106 , pp. 2375-2381
    • Braun, D.1    Longman, R.S.2    Albert, M.L.3
  • 7
    • 12144290925 scopus 로고    scopus 로고
    • Role of interleukin-4 and monocyte chemoattractant protein-1 in the neuropathogenesis of X4 simian human immunodeficiency virus infection in macaques
    • Buch S, Sui Y, Potula R, Pinson D, Adany I, Li Z, Huang M, Li S, Dhillon N, Major E, Narayan O. 2004. Role of interleukin-4 and monocyte chemoattractant protein-1 in the neuropathogenesis of X4 simian human immunodeficiency virus infection in macaques. J Neurovirol 10(Suppl 1):118-124.
    • (2004) J Neurovirol , vol.10 , Issue.SUPPL. 1 , pp. 118-124
    • Buch, S.1    Sui, Y.2    Potula, R.3    Pinson, D.4    Adany, I.5    Li, Z.6    Huang, M.7    Li, S.8    Dhillon, N.9    Major, E.10    Narayan, O.11
  • 8
    • 0036889347 scopus 로고    scopus 로고
    • Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains
    • Burudi EM, Marcondes MC, Watry DD, Zandonatti M, Taffe MA, Fox HS. 2002. Regulation of indoleamine 2,3-dioxygenase expression in simian immunodeficiency virus-infected monkey brains. J Virol 76: 12233-12241.
    • (2002) J Virol , vol.76 , pp. 12233-12241
    • Burudi, E.M.1    Marcondes, M.C.2    Watry, D.D.3    Zandonatti, M.4    Taffe, M.A.5    Fox, H.S.6
  • 9
    • 0035104350 scopus 로고    scopus 로고
    • IL-4 and IL-13 regulate the induction of indoleamine 2,3-dioxygenase activity and the control of Toxoplasma gondii replication in human fibroblasts activated with IFN-γ
    • Chaves AC, Ceravolo IP, Gomes JA, Zani CL, Romanha AJ, Gazzinelli RT. 2001. IL-4 and IL-13 regulate the induction of indoleamine 2,3-dioxygenase activity and the control of Toxoplasma gondii replication in human fibroblasts activated with IFN-γ. Eur J Immunol 31:333-344.
    • (2001) Eur J Immunol , vol.31 , pp. 333-344
    • Chaves, A.C.1    Ceravolo, I.P.2    Gomes, J.A.3    Zani, C.L.4    Romanha, A.J.5    Gazzinelli, R.T.6
  • 10
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE, Jr., Kerr IM, Stark GR. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.
    • (1994) Science , vol.264 , pp. 1415-1421
    • Darnell Jr., J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 13
    • 0031053586 scopus 로고    scopus 로고
    • Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-665.
    • Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R, Cooper GM, Segal RA, Kaplan DR, Greenberg ME. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-665.
  • 14
    • 0028951169 scopus 로고
    • Differential regulation of the human, interferon inducible tryptophanyl-tRNA synthetase by various cytokines in cell lines
    • Fleckner J, Martensen PM, Tolstrup AB, Kjeldgaard NO, Justesen J. 1995. Differential regulation of the human, interferon inducible tryptophanyl-tRNA synthetase by various cytokines in cell lines. Cytokine 7:70-77.
    • (1995) Cytokine , vol.7 , pp. 70-77
    • Fleckner, J.1    Martensen, P.M.2    Tolstrup, A.B.3    Kjeldgaard, N.O.4    Justesen, J.5
  • 16
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase
    • Frumento G, Rotondo R, Tonetti M, Damonte G, Benatti U, Ferrara GB. 2002. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase. J Exp Med 196:459-468.
    • (2002) J Exp Med , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3    Damonte, G.4    Benatti, U.5    Ferrara, G.B.6
  • 17
    • 0033611497 scopus 로고    scopus 로고
    • In vivo regulation of axon extension and pathfinding by growth-cone calcium transients
    • Gomez TM, Spitzer NC. 1999. In vivo regulation of axon extension and pathfinding by growth-cone calcium transients. Nature 397: 350-355.
    • (1999) Nature , vol.397 , pp. 350-355
    • Gomez, T.M.1    Spitzer, N.C.2
  • 18
    • 0033998033 scopus 로고    scopus 로고
    • Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent
    • Grant RS, Naif H, Thuruthyil SJ, Nasr N, Littlejohn T, Takikawa O, Kapoor V. 2000. Induction of indolamine 2,3-dioxygenase in primary human macrophages by human immunodeficiency virus type 1 is strain dependent. J Virol 74:4110-4115.
    • (2000) J Virol , vol.74 , pp. 4110-4115
    • Grant, R.S.1    Naif, H.2    Thuruthyil, S.J.3    Nasr, N.4    Littlejohn, T.5    Takikawa, O.6    Kapoor, V.7
  • 20
    • 0036378826 scopus 로고    scopus 로고
    • Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease
    • Guillemin GJ, Brew BJ. 2002. Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease. Redox Rep 7:199-206.
    • (2002) Redox Rep , vol.7 , pp. 199-206
    • Guillemin, G.J.1    Brew, B.J.2
  • 21
    • 2342507918 scopus 로고    scopus 로고
    • A beta 1-42 induces production of quinolinic acid by human macrophages and microglia
    • Guillemin GJ, Smythe GA, Veas LA, Takikawa O, Brew BJ. 2003. A beta 1-42 induces production of quinolinic acid by human macrophages and microglia. Neuroreport 14:2311-2315.
    • (2003) Neuroreport , vol.14 , pp. 2311-2315
    • Guillemin, G.J.1    Smythe, G.A.2    Veas, L.A.3    Takikawa, O.4    Brew, B.J.5
  • 22
    • 0024358634 scopus 로고
    • Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome
    • Heyes MP, Rubinow D, Lane C, Markey SP. 1989. Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome. Ann Neurol 26:275-277.
    • (1989) Ann Neurol , vol.26 , pp. 275-277
    • Heyes, M.P.1    Rubinow, D.2    Lane, C.3    Markey, S.P.4
  • 24
    • 0036544764 scopus 로고    scopus 로고
    • Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions
    • Hulshof S, Montagne L, De Groot CJ, Van Der Valk P. 2002. Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions. Glia 38:24-35.
    • (2002) Glia , vol.38 , pp. 24-35
    • Hulshof, S.1    Montagne, L.2    De Groot, C.J.3    Van Der Valk, P.4
  • 25
    • 2442554039 scopus 로고    scopus 로고
    • LY294002 inhibits interferon-gamma-stimulated inducible nitric oxide synthase expression in BV2 microglial cells
    • Hwang SY, Jung JS, Lim SJ, Kim JY, Kim TH, Cho KH, Han IO. 2004. LY294002 inhibits interferon-gamma-stimulated inducible nitric oxide synthase expression in BV2 microglial cells. Biochem Biophys Res Commun 318:691-697.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 691-697
    • Hwang, S.Y.1    Jung, J.S.2    Lim, S.J.3    Kim, J.Y.4    Kim, T.H.5    Cho, K.H.6    Han, I.O.7
  • 26
    • 27144448411 scopus 로고    scopus 로고
    • IL-4 inhibits the expression of mouse formyl peptide receptor 2, a receptor for amyloid beta1-42, in TNF-α-activated microglia
    • Iribarren P, Chen K, Hu J, Zhang X, Gong W, Wang JM. 2005. IL-4 inhibits the expression of mouse formyl peptide receptor 2, a receptor for amyloid beta1-42, in TNF-α-activated microglia. J Immunol 175: 6100-6016.
    • (2005) J Immunol , vol.175 , pp. 6100-6016
    • Iribarren, P.1    Chen, K.2    Hu, J.3    Zhang, X.4    Gong, W.5    Wang, J.M.6
  • 27
    • 0038517976 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-13 signaling connections maps
    • Kelly-Welch AE, Hanson EM, Boothby MR, Keegan AD. 2003. Interleukin-4 and interleukin-13 signaling connections maps. Science 300:1527-1528.
    • (2003) Science , vol.300 , pp. 1527-1528
    • Kelly-Welch, A.E.1    Hanson, E.M.2    Boothby, M.R.3    Keegan, A.D.4
  • 28
  • 29
    • 0033136694 scopus 로고    scopus 로고
    • IL-4 inhibits the production of TNF-α and IL-12 by STAT6-dependent and -independent mechanisms
    • Levings MK, Schrader JW. 1999. IL-4 inhibits the production of TNF-α and IL-12 by STAT6-dependent and -independent mechanisms. J Immunol 162:5224-5229.
    • (1999) J Immunol , vol.162 , pp. 5224-5229
    • Levings, M.K.1    Schrader, J.W.2
  • 30
    • 0034008926 scopus 로고    scopus 로고
    • Transient translocation and activation of protein phosphatase 2A during mast cell secretion
    • Ludowyke RI, Holst J, Mudge LM, Sim AT. 2000. Transient translocation and activation of protein phosphatase 2A during mast cell secretion. J Biol Chem 275:6144-6152.
    • (2000) J Biol Chem , vol.275 , pp. 6144-6152
    • Ludowyke, R.I.1    Holst, J.2    Mudge, L.M.3    Sim, A.T.4
  • 32
    • 1842431124 scopus 로고    scopus 로고
    • Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis
    • Maffei CM, Mirels LF, Sobel RA, Clemons KV, Stevens DA. 2004. Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis. Infect Immun 72:2338-2349.
    • (2004) Infect Immun , vol.72 , pp. 2338-2349
    • Maffei, C.M.1    Mirels, L.F.2    Sobel, R.A.3    Clemons, K.V.4    Stevens, D.A.5
  • 33
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. 2004. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 34
    • 0037057345 scopus 로고    scopus 로고
    • Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase
    • Mochizuki Y, Tsuda S, Kanetake H, Kanda S. 2002. Negative regulation of urokinase-type plasminogen activator production through FGF-2-mediated activation of phosphoinositide 3-kinase. Oncogene 21:7027-7033.
    • (2002) Oncogene , vol.21 , pp. 7027-7033
    • Mochizuki, Y.1    Tsuda, S.2    Kanetake, H.3    Kanda, S.4
  • 35
    • 0029928417 scopus 로고    scopus 로고
    • The expanding universe of T-cell subsets: Th1, Th2 and more
    • Mosmann TR, Sad S. 1996. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 17:138-146.
    • (1996) Immunol Today , vol.17 , pp. 138-146
    • Mosmann, T.R.1    Sad, S.2
  • 39
    • 0141533178 scopus 로고    scopus 로고
    • Tryptophan depletion and HIV infection: A metabolic link to pathogenesis
    • Murray MF. 2003. Tryptophan depletion and HIV infection: A metabolic link to pathogenesis. Lancet Infect Dis 3:644-652.
    • (2003) Lancet Infect Dis , vol.3 , pp. 644-652
    • Murray, M.F.1
  • 40
    • 0027976346 scopus 로고
    • Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes
    • Musso T, Gusella GL, Brooks A, Longo DL, Varesio L. 1994. Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes. Blood 83:1408-1411.
    • (1994) Blood , vol.83 , pp. 1408-1411
    • Musso, T.1    Gusella, G.L.2    Brooks, A.3    Longo, D.L.4    Varesio, L.5
  • 41
    • 0035980056 scopus 로고    scopus 로고
    • TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3′-kinase/protein kinase B signaling pathway
    • Nguyen MH, Ho JM, Beattie BK, Barber DL. 2001. TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3′-kinase/protein kinase B signaling pathway. J Biol Chem 276:32704-32713.
    • (2001) J Biol Chem , vol.276 , pp. 32704-32713
    • Nguyen, M.H.1    Ho, J.M.2    Beattie, B.K.3    Barber, D.L.4
  • 42
    • 0032911061 scopus 로고    scopus 로고
    • Class II transactivator and class II MHC gene expression in microglia: Modulation by the cytokines TGF-β, IL-4, IL-13 and IL-10
    • O'Keefe GM, Nguyen VT, Benveniste EN. 1999. Class II transactivator and class II MHC gene expression in microglia: Modulation by the cytokines TGF-β, IL-4, IL-13 and IL-10. Eur J Immunol 29:1275-1285.
    • (1999) Eur J Immunol , vol.29 , pp. 1275-1285
    • O'Keefe, G.M.1    Nguyen, V.T.2    Benveniste, E.N.3
  • 43
    • 0026559756 scopus 로고
    • IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity
    • Oswald IP, Gazzinelli RT, Sher A, James SL. 1992. IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity. J Immunol 148:3578-3582.
    • (1992) J Immunol , vol.148 , pp. 3578-3582
    • Oswald, I.P.1    Gazzinelli, R.T.2    Sher, A.3    James, S.L.4
  • 44
    • 0033548627 scopus 로고    scopus 로고
    • Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells
    • Pahan K, Raymond JR, Singh I. 1999. Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. J Biol Chem 274:7528-7536.
    • (1999) J Biol Chem , vol.274 , pp. 7528-7536
    • Pahan, K.1    Raymond, J.R.2    Singh, I.3
  • 47
    • 0042884203 scopus 로고    scopus 로고
    • Synergistic transcriptional activation of indoleamine dioxygenase by IFN-γ and tumor necrosis factor-alpha
    • Robinson CM, Shirey KA, Carlin JM. 2003. Synergistic transcriptional activation of indoleamine dioxygenase by IFN-γ and tumor necrosis factor-alpha. J Interferon Cytokine Res 23:413-421.
    • (2003) J Interferon Cytokine Res , vol.23 , pp. 413-421
    • Robinson, C.M.1    Shirey, K.A.2    Carlin, J.M.3
  • 48
    • 0026343599 scopus 로고
    • Interferon induces tryptophanyl-tRNA synthetase expression in human fibroblasts
    • Rubin BY, Anderson SL, Xing L, Powell RJ, Tate WP. 1991. Interferon induces tryptophanyl-tRNA synthetase expression in human fibroblasts. J Biol Chem 266:24245-24248.
    • (1991) J Biol Chem , vol.266 , pp. 24245-24248
    • Rubin, B.Y.1    Anderson, S.L.2    Xing, L.3    Powell, R.J.4    Tate, W.P.5
  • 49
    • 0036341332 scopus 로고    scopus 로고
    • Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis
    • Sakurai K, Zou JP, Tschetter JR, Ward JM, Shearer GM. 2002. Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis. J Neuroimmunol 129:186-196.
    • (2002) J Neuroimmunol , vol.129 , pp. 186-196
    • Sakurai, K.1    Zou, J.P.2    Tschetter, J.R.3    Ward, J.M.4    Shearer, G.M.5
  • 50
    • 0025900245 scopus 로고
    • Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system
    • Sedgwick JD, Schwender S, Imrich H, Dorries R, Butcher GW, ter Meulen V. 1991. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc Natl Acad Sci USA 88:7438-7442.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7438-7442
    • Sedgwick, J.D.1    Schwender, S.2    Imrich, H.3    Dorries, R.4    Butcher, G.W.5    ter Meulen, V.6
  • 51
    • 2342656874 scopus 로고    scopus 로고
    • Microglia expressing interleukin-13 undergo cell death and contribute to neuronal survival in vivo
    • Shin WH, Lee DY, Park KW, Kim SU, Yang MS, Joe EH, Jin BK. 2004. Microglia expressing interleukin-13 undergo cell death and contribute to neuronal survival in vivo. Glia 46:142-152.
    • (2004) Glia , vol.46 , pp. 142-152
    • Shin, W.H.1    Lee, D.Y.2    Park, K.W.3    Kim, S.U.4    Yang, M.S.5    Joe, E.H.6    Jin, B.K.7
  • 52
    • 0035123904 scopus 로고    scopus 로고
    • Kynurenines in the CNS: From endogenous obscurity to therapeutic importance
    • Stone TW. 2001. Kynurenines in the CNS: From endogenous obscurity to therapeutic importance. Prog Neurobiol 64:185-218.
    • (2001) Prog Neurobiol , vol.64 , pp. 185-218
    • Stone, T.W.1
  • 53
    • 0035255055 scopus 로고    scopus 로고
    • IL-4, IL-10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line
    • Szczepanik AM, Funes S, Petko W, Ringheim GE. 2001. IL-4, IL-10 and IL-13 modulate A beta(1-42)-induced cytokine and chemokine production in primary murine microglia and a human monocyte cell line. J Neuroimmunol 113:49-62.
    • (2001) J Neuroimmunol , vol.113 , pp. 49-62
    • Szczepanik, A.M.1    Funes, S.2    Petko, W.3    Ringheim, G.E.4
  • 54
    • 0037136266 scopus 로고    scopus 로고
    • Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: Mediation of suppression by tryptophan metabolites
    • Terness P, Bauer TM, Rose L, Dufter C, Watzlik A, Simon H, Opelz G. 2002. Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: Mediation of suppression by tryptophan metabolites. J Exp Med 196:447-457.
    • (2002) J Exp Med , vol.196 , pp. 447-457
    • Terness, P.1    Bauer, T.M.2    Rose, L.3    Dufter, C.4    Watzlik, A.5    Simon, H.6    Opelz, G.7
  • 55
    • 0033604577 scopus 로고    scopus 로고
    • Signaling by distinct classes of phosphoinositide 3-kinases
    • Vanhaesebroeck B, Waterneld MD. 1999. Signaling by distinct classes of phosphoinositide 3-kinases. Exp Cell Res 253:239-254.
    • (1999) Exp Cell Res , vol.253 , pp. 239-254
    • Vanhaesebroeck, B.1    Waterneld, M.D.2
  • 56
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen Z, Zhong Z, Darnell JE Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell Jr., J.E.3
  • 57
    • 0034280245 scopus 로고    scopus 로고
    • Interferon-gamma-induced tryptophan degradation: Neuropsychiatry; and immunological consequences
    • Widner B, Ledochowski M, Fuchs D. 2000. Interferon-gamma-induced tryptophan degradation: Neuropsychiatry; and immunological consequences. Curr Drug Metab 1:193-204.
    • (2000) Curr Drug Metab , vol.1 , pp. 193-204
    • Widner, B.1    Ledochowski, M.2    Fuchs, D.3
  • 59
    • 0031666669 scopus 로고    scopus 로고
    • Modulation of cellular tryptophan metabolism in human fibroblasts by transforming growth factor-beta: Selective inhibition of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA synthetase gene expression
    • Yuan W, Collado-Hidalgo A, Yufit T, Taylor M, Varga J. 1998. Modulation of cellular tryptophan metabolism in human fibroblasts by transforming growth factor-beta: Selective inhibition of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA synthetase gene expression. J Cell Physiol 177:174-186.
    • (1998) J Cell Physiol , vol.177 , pp. 174-186
    • Yuan, W.1    Collado-Hidalgo, A.2    Yufit, T.3    Taylor, M.4    Varga, J.5


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