메뉴 건너뛰기




Volumn 163, Issue , 2017, Pages 115-124

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

Author keywords

Biomarker; Brain ageing; Convolutional neural networks; Deep learning; Gaussian processes; Heritability; Neuroimaging; Reliability

Indexed keywords

ADULT; AGE DETERMINATION; AGED; AGING; ARTICLE; ARTIFICIAL NEURAL NETWORK; BRAIN; BRAIN AGING; CONVOLUTIONAL NEURAL NETWORK; DEEP LEARNING; DIZYGOTIC TWINS; FEMALE; GRAY MATTER; HERITABILITY; HUMAN; MACHINE LEARNING; MALE; MONOZYGOTIC TWINS; NEUROIMAGING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; TEST RETEST RELIABILITY; WHITE MATTER; ADOLESCENT; DIAGNOSTIC IMAGING; IMAGE PROCESSING; MIDDLE AGED; PATHOLOGY; PHENOTYPE; PROCEDURES; VERY ELDERLY; YOUNG ADULT;

EID: 85029673464     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2017.07.059     Document Type: Article
Times cited : (627)

References (68)
  • 1
    • 79960343607 scopus 로고    scopus 로고
    • Dementia: a problem for our age
    • Abbott, A., Dementia: a problem for our age. Nature 475 (2011), S2–S4.
    • (2011) Nature , vol.475 , pp. S2-S4
    • Abbott, A.1
  • 2
    • 0016355478 scopus 로고
    • A new look at the statistical model identification
    • Akaike, H., A new look at the statistical model identification. IEEE Trans. Automat. Control 19 (1974), 716–723, 10.1109/TAC.1974.1100705.
    • (1974) IEEE Trans. Automat. Control , vol.19 , pp. 716-723
    • Akaike, H.1
  • 3
    • 34548832230 scopus 로고    scopus 로고
    • A fast diffeomorphic image registration algorithm
    • Ashburner, J., A fast diffeomorphic image registration algorithm. NeuroImage 38 (2007), 95–113, 10.1016/j.neuroimage.2007.07.007.
    • (2007) NeuroImage , vol.38 , pp. 95-113
    • Ashburner, J.1
  • 4
    • 38849187993 scopus 로고    scopus 로고
    • Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain
    • Avants, B.B., Epstein, C.L., Grossman, M., Gee, J.C., Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain. Med. Image Anal. 12 (2008), 26–41, 10.1016/j.media.2007.06.004.
    • (2008) Med. Image Anal. , vol.12 , pp. 26-41
    • Avants, B.B.1    Epstein, C.L.2    Grossman, M.3    Gee, J.C.4
  • 6
    • 41649098815 scopus 로고    scopus 로고
    • A comparison of methods for the automated calculation of volumes and atrophy rates in the hippocampus
    • Barnes, J., Foster, J., Boyes, R.G., Pepple, T., Moore, E.K., Schott, J.M., Frost, C., Scahill, R.I., Fox, N.C., A comparison of methods for the automated calculation of volumes and atrophy rates in the hippocampus. NeuroImage 40 (2008), 1655–1671, 10.1016/j.neuroimage.2008.01.012.
    • (2008) NeuroImage , vol.40 , pp. 1655-1671
    • Barnes, J.1    Foster, J.2    Boyes, R.G.3    Pepple, T.4    Moore, E.K.5    Schott, J.M.6    Frost, C.7    Scahill, R.I.8    Fox, N.C.9
  • 7
    • 84891372625 scopus 로고    scopus 로고
    • Heritability of brain volumes in older adults: the older Australian twins study
    • e935-937.e918
    • Batouli, S.A.H., Sachdev, P.S., Wen, W., Wright, M.J., Ames, D., Trollor, J.N., Heritability of brain volumes in older adults: the older Australian twins study. Neurobiol. Aging, 35, 2014, 937, 10.1016/j.neurobiolaging.2013.10.079 e935-937.e918.
    • (2014) Neurobiol. Aging , vol.35 , pp. 937
    • Batouli, S.A.H.1    Sachdev, P.S.2    Wen, W.3    Wright, M.J.4    Ames, D.5    Trollor, J.N.6
  • 8
    • 84888217465 scopus 로고    scopus 로고
    • The heritability of volumes of brain structures and its relationship to age: a review of twin and family studies
    • Batouli, S.A.H., Trollor, J.N., Wen, W., Sachdev, P.S., The heritability of volumes of brain structures and its relationship to age: a review of twin and family studies. Ageing Res. Rev. 13 (2014), 1–9, 10.1016/j.arr.2013.10.003.
    • (2014) Ageing Res. Rev. , vol.13 , pp. 1-9
    • Batouli, S.A.H.1    Trollor, J.N.2    Wen, W.3    Sachdev, P.S.4
  • 10
    • 84988872619 scopus 로고    scopus 로고
    • The Wilson Effect: the increase in heritability of IQ with age
    • Bouchard, T.J., The Wilson Effect: the increase in heritability of IQ with age. Twin Res. Hum. Genet. 16 (2013), 923–930, 10.1017/thg.2013.54.
    • (2013) Twin Res. Hum. Genet. , vol.16 , pp. 923-930
    • Bouchard, T.J.1
  • 11
    • 84923318381 scopus 로고    scopus 로고
    • Big data deep learning: challenges and perspectives
    • Chen, X.W., Lin, X., Big data deep learning: challenges and perspectives. IEEE Access 2 (2014), 514–525, 10.1109/ACCESS.2014.2325029.
    • (2014) IEEE Access , vol.2 , pp. 514-525
    • Chen, X.W.1    Lin, X.2
  • 13
    • 84925440897 scopus 로고    scopus 로고
    • Prediction of brain age suggests accelerated atrophy after traumatic brain injury
    • Cole, J.H., Leech, R., Sharp, D.J., for the Alzheimer's Disease Neuroimaging, I. Prediction of brain age suggests accelerated atrophy after traumatic brain injury. Ann. Neurol. 77 (2015), 571–581, 10.1002/ana.24367.
    • (2015) Ann. Neurol. , vol.77 , pp. 571-581
    • Cole, J.H.1    Leech, R.2    Sharp, D.J.3
  • 16
    • 84903724014 scopus 로고    scopus 로고
    • Deep learning: methods and applications
    • Deng, L., Yu, D., Deep learning: methods and applications. Found. Trends Signal Process. 7 (2013), 197–387, 10.1561/2000000039.
    • (2013) Found. Trends Signal Process. , vol.7 , pp. 197-387
    • Deng, L.1    Yu, D.2
  • 21
    • 84870617803 scopus 로고    scopus 로고
    • Longitudinal changes in individual BrainAGE in healthy aging, mild cognitive impairment, and Alzheimer's Disease
    • Franke, K., Gaser, C., Longitudinal changes in individual BrainAGE in healthy aging, mild cognitive impairment, and Alzheimer's Disease. GeroPsych. J. Gerontopsychology Geriatr. Psychiatry 25 (2012), 235–245.
    • (2012) GeroPsych. J. Gerontopsychology Geriatr. Psychiatry , vol.25 , pp. 235-245
    • Franke, K.1    Gaser, C.2
  • 22
    • 84895792731 scopus 로고    scopus 로고
    • Advanced BrainAGE in older adults with type 2 diabetes mellitus
    • Franke, K., Gaser, C., Manor, B., Novak, V., Advanced BrainAGE in older adults with type 2 diabetes mellitus. Front. Aging Neurosci., 5(90), 2013, 10.3389/fnagi.2013.00090.
    • (2013) Front. Aging Neurosci. , vol.5 , Issue.90
    • Franke, K.1    Gaser, C.2    Manor, B.3    Novak, V.4
  • 23
    • 77249176542 scopus 로고    scopus 로고
    • Estimating the age of healthy subjects from T1-weighted MRI scans using kernel methods: exploring the influence of various parameters
    • Franke, K., Ziegler, G., Klöppel, S., Gaser, C., Estimating the age of healthy subjects from T1-weighted MRI scans using kernel methods: exploring the influence of various parameters. NeuroImage 50 (2010), 883–892.
    • (2010) NeuroImage , vol.50 , pp. 883-892
    • Franke, K.1    Ziegler, G.2    Klöppel, S.3    Gaser, C.4
  • 24
    • 84879516484 scopus 로고    scopus 로고
    • BrainAGE in mild cognitive impaired patients: predicting the conversion to Alzheimer's disease
    • Gaser, C., Franke, K., Klöppel, S., Koutsouleris, N., Sauer, H., BrainAGE in mild cognitive impaired patients: predicting the conversion to Alzheimer's disease. PLoS One, 8, 2013.
    • (2013) PLoS One , vol.8
    • Gaser, C.1    Franke, K.2    Klöppel, S.3    Koutsouleris, N.4    Sauer, H.5
  • 25
    • 84880889673 scopus 로고    scopus 로고
    • Selecting a sample size for studies with repeated measures
    • Guo, Y., Logan, H.L., Glueck, D.H., Muller, K.E., Selecting a sample size for studies with repeated measures. BMC Med. Res. Methodol. 13 (2013), 1–8, 10.1186/1471-2288-13-100.
    • (2013) BMC Med. Res. Methodol. , vol.13 , pp. 1-8
    • Guo, Y.1    Logan, H.L.2    Glueck, D.H.3    Muller, K.E.4
  • 26
    • 80051947323 scopus 로고    scopus 로고
    • The genetics of cognitive ability and cognitive ageing in healthy older people
    • Harris, S.E., Deary, I.J., The genetics of cognitive ability and cognitive ageing in healthy older people. Trends Cognitive Sci. 15 (2011), 388–394, 10.1016/j.tics.2011.07.004.
    • (2011) Trends Cognitive Sci. , vol.15 , pp. 388-394
    • Harris, S.E.1    Deary, I.J.2
  • 27
    • 84969584486 scopus 로고    scopus 로고
    • Batch normalization: accelerating deep network training by reducing internal covariate shift
    • 448-456
    • Ioffe, S., Szegedy, C., Batch normalization: accelerating deep network training by reducing internal covariate shift. Comput. Res. Repos., 2015 448-456.
    • (2015) Comput. Res. Repos.
    • Ioffe, S.1    Szegedy, C.2
  • 28
    • 84948566123 scopus 로고    scopus 로고
    • Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood
    • Irimia, A., Torgerson, C.M., Goh, S.-Y.M., Horn, J.D., Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Brain Imaging Behav. 9 (2014), 678–689, 10.1007/s11682-014-9321-0.
    • (2014) Brain Imaging Behav. , vol.9 , pp. 678-689
    • Irimia, A.1    Torgerson, C.M.2    Goh, S.-Y.M.3    Horn, J.D.4
  • 29
    • 0035384136 scopus 로고    scopus 로고
    • A global optimisation method for robust affine registration of brain images
    • Jenkinson, M., Smith, S., A global optimisation method for robust affine registration of brain images. Med. Image Anal. 5 (2001), 143–156.
    • (2001) Med. Image Anal. , vol.5 , pp. 143-156
    • Jenkinson, M.1    Smith, S.2
  • 30
    • 84870183903 scopus 로고    scopus 로고
    • 3D convolutional neural networks for human action recognition
    • Ji, S., Xu, W., Yang, M., Yu, K., 3D convolutional neural networks for human action recognition. IEEE Trans. Pattern Anal. Mach. Intell. 35 (2013), 221–231, 10.1109/TPAMI.2012.59.
    • (2013) IEEE Trans. Pattern Anal. Mach. Intell. , vol.35 , pp. 221-231
    • Ji, S.1    Xu, W.2    Yang, M.3    Yu, K.4
  • 33
    • 84959203985 scopus 로고    scopus 로고
    • Deep MRI brain extraction: a 3D convolutional neural network for skull stripping
    • Kleesiek, J., Urban, G., Hubert, A., Schwarz, D., Maier-Hein, K., Bendszus, M., Biller, A., Deep MRI brain extraction: a 3D convolutional neural network for skull stripping. NeuroImage 129 (2016), 460–469, 10.1016/j.neuroimage.2016.01.024.
    • (2016) NeuroImage , vol.129 , pp. 460-469
    • Kleesiek, J.1    Urban, G.2    Hubert, A.3    Schwarz, D.4    Maier-Hein, K.5    Bendszus, M.6    Biller, A.7
  • 35
    • 84879879457 scopus 로고    scopus 로고
    • Neighbourhood approximation using randomized forests
    • Konukoglu, E., Glocker, B., Zikic, D., Criminisi, A., Neighbourhood approximation using randomized forests. Med. Image Anal. 17 (2013), 790–804, 10.1016/j.media.2013.04.013.
    • (2013) Med. Image Anal. , vol.17 , pp. 790-804
    • Konukoglu, E.1    Glocker, B.2    Zikic, D.3    Criminisi, A.4
  • 39
    • 0032203257 scopus 로고    scopus 로고
    • Gradient-based learning applied to document recognition
    • Lecun, Y., Bottou, L., Bengio, Y., Haffner, P., Gradient-based learning applied to document recognition. Proc. IEEE 86 (1998), 2278–2324, 10.1109/5.726791.
    • (1998) Proc. IEEE , vol.86 , pp. 2278-2324
    • Lecun, Y.1    Bottou, L.2    Bengio, Y.3    Haffner, P.4
  • 40
    • 77953360759 scopus 로고    scopus 로고
    • Genetic influences on cognitive functions in the elderly: a selective review of twin studies
    • Lee, T., Henry, J.D., Trollor, J.N., Sachdev, P.S., Genetic influences on cognitive functions in the elderly: a selective review of twin studies. Brain Res. Rev. 64 (2010), 1–13, 10.1016/j.brainresrev.2010.02.001.
    • (2010) Brain Res. Rev. , vol.64 , pp. 1-13
    • Lee, T.1    Henry, J.D.2    Trollor, J.N.3    Sachdev, P.S.4
  • 41
    • 84894026581 scopus 로고    scopus 로고
    • The contributions of twin studies to the understanding of brain ageing and neurocognitive disorders
    • Lee, T., Sachdev, P., The contributions of twin studies to the understanding of brain ageing and neurocognitive disorders. Curr. Opin. Psychiatry 27 (2014), 122–127, 10.1097/yco.0000000000000039.
    • (2014) Curr. Opin. Psychiatry , vol.27 , pp. 122-127
    • Lee, T.1    Sachdev, P.2
  • 43
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • Lu, T., Pan, Y., Kao, S.Y., Li, C., Kohane, I., Chan, J., Yankner, B.A., Gene regulation and DNA damage in the ageing human brain. Nature 429 (2004), 883–891, 10.1038/nature02661.
    • (2004) Nature , vol.429 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.Y.3    Li, C.4    Kohane, I.5    Chan, J.6    Yankner, B.A.7
  • 44
    • 84964462312 scopus 로고    scopus 로고
    • Estimating brain age using high-resolution pattern recognition: younger brains in long-term meditation practitioners
    • Luders, E., Cherbuin, N., Gaser, C., Estimating brain age using high-resolution pattern recognition: younger brains in long-term meditation practitioners. NeuroImage 134 (2016), 508–513, 10.1016/j.neuroimage.2016.04.007.
    • (2016) NeuroImage , vol.134 , pp. 508-513
    • Luders, E.1    Cherbuin, N.2    Gaser, C.3
  • 45
    • 0030976148 scopus 로고    scopus 로고
    • Substantial genetic influence on cognitive abilities in twins 80 or more years old
    • McClearn, G.E., Johansson, B., Berg, S., Pedersen, N.L., Ahern, F., Petrill, S.A., Plomin, R., Substantial genetic influence on cognitive abilities in twins 80 or more years old. Science 276 (1997), 1560–1563, 10.1126/science.276.5318.1560.
    • (1997) Science , vol.276 , pp. 1560-1563
    • McClearn, G.E.1    Johansson, B.2    Berg, S.3    Pedersen, N.L.4    Ahern, F.5    Petrill, S.A.6    Plomin, R.7
  • 46
    • 77957306385 scopus 로고    scopus 로고
    • Correcting eddy current and motion effects by affine whole-brain registrations: evaluation of three-dimensional distortions and comparison with slicewise correction
    • Mohammadi, S., Möller, H.E., Kugel, H., Müller, D.K., Deppe, M., Correcting eddy current and motion effects by affine whole-brain registrations: evaluation of three-dimensional distortions and comparison with slicewise correction. Magn. Reson. Med. 64 (2010), 1047–1056, 10.1002/mrm.22501.
    • (2010) Magn. Reson. Med. , vol.64 , pp. 1047-1056
    • Mohammadi, S.1    Möller, H.E.2    Kugel, H.3    Müller, D.K.4    Deppe, M.5
  • 47
    • 78649531345 scopus 로고    scopus 로고
    • Scan-rescan reliability of subcortical brain volumes derived from automated segmentation
    • Morey, R.A., Selgrade, E.S., Wagner, H.R. 2nd, Huettel, S.A., Wang, L., McCarthy, G., Scan-rescan reliability of subcortical brain volumes derived from automated segmentation. Hum. Brain Mapp. 31 (2010), 1751–1762, 10.1002/hbm.20973.
    • (2010) Hum. Brain Mapp. , vol.31 , pp. 1751-1762
    • Morey, R.A.1    Selgrade, E.S.2    Wagner, H.R.3    Huettel, S.A.4    Wang, L.5    McCarthy, G.6
  • 48
    • 84875660261 scopus 로고    scopus 로고
    • Prediction of individual subject's age across the human lifespan using diffusion tensor imaging: a machine learning approach
    • Mwangi, B., Hasan, K.M., Soares, J.C., Prediction of individual subject's age across the human lifespan using diffusion tensor imaging: a machine learning approach. NeuroImage 75 (2013), 58–67, 10.1016/j.neuroimage.2013.02.055.
    • (2013) NeuroImage , vol.75 , pp. 58-67
    • Mwangi, B.1    Hasan, K.M.2    Soares, J.C.3
  • 49
    • 84880559618 scopus 로고    scopus 로고
    • Automated subcortical segmentation using FIRST: test-retest reliability, interscanner reliability, and comparison to manual segmentation
    • Nugent, A.C., Luckenbaugh, D.A., Wood, S.E., Bogers, W., Zarate, C.A., Drevets, W.C., Automated subcortical segmentation using FIRST: test-retest reliability, interscanner reliability, and comparison to manual segmentation. Hum. Brain Mapp. 34 (2013), 2313–2329, 10.1002/hbm.22068.
    • (2013) Hum. Brain Mapp. , vol.34 , pp. 2313-2329
    • Nugent, A.C.1    Luckenbaugh, D.A.2    Wood, S.E.3    Bogers, W.4    Zarate, C.A.5    Drevets, W.C.6
  • 50
    • 85017296103 scopus 로고    scopus 로고
    • Structural brain changes in medically refractory focal epilepsy resemble premature brain aging
    • Pardoe, H.R., Cole, J.H., Blackmon, K., Thesen, T., Kuzniecky, R., Structural brain changes in medically refractory focal epilepsy resemble premature brain aging. Epilepsy Res. 133 (2017), 28–32, 10.1016/j.eplepsyres.2017.03.007.
    • (2017) Epilepsy Res. , vol.133 , pp. 28-32
    • Pardoe, H.R.1    Cole, J.H.2    Blackmon, K.3    Thesen, T.4    Kuzniecky, R.5
  • 51
    • 84965023577 scopus 로고    scopus 로고
    • Motion and morphometry in clinical and nonclinical populations
    • Pardoe, H.R., Kucharsky Hiess, R., Kuzniecky, R., Motion and morphometry in clinical and nonclinical populations. NeuroImage 135 (2016), 177–185, 10.1016/j.neuroimage.2016.05.005.
    • (2016) NeuroImage , vol.135 , pp. 177-185
    • Pardoe, H.R.1    Kucharsky Hiess, R.2    Kuzniecky, R.3
  • 52
    • 84938872693 scopus 로고    scopus 로고
    • Predicting Alzheimer's disease: a neuroimaging study with 3D convolutional neural networks
    • arXiv:1502.02506
    • Payan, A., Montana, G., Predicting Alzheimer's disease: a neuroimaging study with 3D convolutional neural networks. Comput. Res. Repos., 2015 arXiv:1502.02506.
    • (2015) Comput. Res. Repos.
    • Payan, A.1    Montana, G.2
  • 53
    • 33144480066 scopus 로고    scopus 로고
    • Ageing and the brain
    • Peters, R., Ageing and the brain. Postgrad. Med. J. 82 (2006), 84–88, 10.1136/pgmj.2005.036665.
    • (2006) Postgrad. Med. J. , vol.82 , pp. 84-88
    • Peters, R.1
  • 55
    • 84951019234 scopus 로고    scopus 로고
    • Which Metrics Should Be Used in Non-linear Registration Evaluation?, Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    • Ribeiro, A.S., Nutt, D.J., McGonigle, J., Which Metrics Should Be Used in Non-linear Registration Evaluation?, Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2015, 388–395.
    • (2015) , pp. 388-395
    • Ribeiro, A.S.1    Nutt, D.J.2    McGonigle, J.3
  • 56
    • 0036596190 scopus 로고    scopus 로고
    • Analytic approaches to twin data using structural equation models
    • Rijsdijk, F.V., Sham, P.C., Analytic approaches to twin data using structural equation models. Briefings Bioinforma. 3 (2002), 119–133.
    • (2002) Briefings Bioinforma. , vol.3 , pp. 119-133
    • Rijsdijk, F.V.1    Sham, P.C.2
  • 57
    • 0034431849 scopus 로고    scopus 로고
    • Stereotaxic display of brain lesions
    • Rorden, C., Brett, M., Stereotaxic display of brain lesions. Behav. Neurol. 12 (2000), 191–200.
    • (2000) Behav. Neurol. , vol.12 , pp. 191-200
    • Rorden, C.1    Brett, M.2
  • 58
    • 85029696279 scopus 로고    scopus 로고
    • DeepAD: Alzheimer's disease classification via deep convolutional neural networks using MRI and fMRI
    • Sarraf, S., Tofighi, G., DeepAD: Alzheimer's disease classification via deep convolutional neural networks using MRI and fMRI. bioRxiv, 2016, 70441, 10.1101/070441.
    • (2016) bioRxiv , pp. 70441
    • Sarraf, S.1    Tofighi, G.2
  • 59
    • 84973344384 scopus 로고    scopus 로고
    • Accelerated brain aging in schizophrenia: a longitudinal pattern recognition study
    • Schnack, H.G., Haren, N.E.M.v., Nieuwenhuis, M., Pol, H.E.H., Cahn, W., Kahn, R.S., Accelerated brain aging in schizophrenia: a longitudinal pattern recognition study. Am. J. Psychiatry 173 (2016), 607–616, 10.1176/appi.ajp.2015.15070922.
    • (2016) Am. J. Psychiatry , vol.173 , pp. 607-616
    • Schnack, H.G.1    Haren, N.E.M.V.2    Nieuwenhuis, M.3    Pol, H.E.H.4    Cahn, W.5    Kahn, R.S.6
  • 61
    • 48249153186 scopus 로고
    • Intraclass correlations: uses in assessing rater reliability
    • Shrout, P.E., Fleiss, J.L., Intraclass correlations: uses in assessing rater reliability. Psychol. Bull. 86 (1979), 420–428.
    • (1979) Psychol. Bull. , vol.86 , pp. 420-428
    • Shrout, P.E.1    Fleiss, J.L.2
  • 62
    • 84960359234 scopus 로고    scopus 로고
    • Differences between chronological and brain age are related to education and self-reported physical activity
    • Steffener, J., Habeck, C., O'Shea, D., Razlighi, Q., Bherer, L., Stern, Y., Differences between chronological and brain age are related to education and self-reported physical activity. Neurobiol. Aging 40 (2016), 138–144, 10.1016/j.neurobiolaging.2016.01.014.
    • (2016) Neurobiol. Aging , vol.40 , pp. 138-144
    • Steffener, J.1    Habeck, C.2    O'Shea, D.3    Razlighi, Q.4    Bherer, L.5    Stern, Y.6
  • 63
    • 84892925549 scopus 로고    scopus 로고
    • Predicting the Age of Healthy Adults from Structural MRI by Sparse Representation
    • Su, L., Wang, L., Hu, D., Predicting the Age of Healthy Adults from Structural MRI by Sparse Representation. 2013, 271–279.
    • (2013) , pp. 271-279
    • Su, L.1    Wang, L.2    Hu, D.3
  • 65
    • 4544233053 scopus 로고    scopus 로고
    • Caliban's heritance and the genetics of neuronal aging
    • Teter, B., Finch, C.E., Caliban's heritance and the genetics of neuronal aging. Trends Neurosci. 27 (2004), 627–632, 10.1016/j.tins.2004.08.005.
    • (2004) Trends Neurosci. , vol.27 , pp. 627-632
    • Teter, B.1    Finch, C.E.2
  • 66
    • 84891794579 scopus 로고    scopus 로고
    • Shared and unique genetic and environmental influences on aging-related changes in multiple cognitive abilities
    • Tucker-Drob, E.M., Reynolds, C.A., Finkel, D., Pedersen, N.L., Shared and unique genetic and environmental influences on aging-related changes in multiple cognitive abilities. Dev. Psychol. 50 (2014), 152–166, 10.1037/a0032468.
    • (2014) Dev. Psychol. , vol.50 , pp. 152-166
    • Tucker-Drob, E.M.1    Reynolds, C.A.2    Finkel, D.3    Pedersen, N.L.4
  • 67
    • 84919394839 scopus 로고    scopus 로고
    • Comparison of 10 brain tissue segmentation methods using revisited IBSR annotations
    • Valverde, S., Oliver, A., Cabezas, M., Roura, E., Lladó, X., Comparison of 10 brain tissue segmentation methods using revisited IBSR annotations. J. Magn. Reson. Imaging 41 (2015), 93–101, 10.1002/jmri.24517.
    • (2015) J. Magn. Reson. Imaging , vol.41 , pp. 93-101
    • Valverde, S.1    Oliver, A.2    Cabezas, M.3    Roura, E.4    Lladó, X.5
  • 68
    • 77956230065 scopus 로고    scopus 로고
    • Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies
    • Winkler, A.M., Kochunov, P., Blangero, J., Almasy, L., Zilles, K., Fox, P.T., Duggirala, R., Glahn, D.C., Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. NeuroImage 53 (2010), 1135–1146, 10.1016/j.neuroimage.2009.12.028.
    • (2010) NeuroImage , vol.53 , pp. 1135-1146
    • Winkler, A.M.1    Kochunov, P.2    Blangero, J.3    Almasy, L.4    Zilles, K.5    Fox, P.T.6    Duggirala, R.7    Glahn, D.C.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.