메뉴 건너뛰기




Volumn 6, Issue 9, 2017, Pages 1722-1731

Engineered Assimilation of Exogenous and Endogenous Formate in Escherichia coli

Author keywords

auxotrophic strains; formate metabolism; formate THF ligase; one carbon metabolism; pyruvate formate lyase; reductive glycine pathway; serine threonine cycle; threonine cleavage

Indexed keywords

FORMIC ACID; GLYCINE; PYRUVIC ACID; SERINE; THREONINE; ESCHERICHIA COLI PROTEIN; FORMIC ACID DERIVATIVE;

EID: 85029528338     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.7b00086     Document Type: Article
Times cited : (68)

References (54)
  • 1
    • 84991711408 scopus 로고    scopus 로고
    • Large-scale bioprocess competitiveness: The potential of dynamic metabolic control in two-stage fermentations
    • Burg, J. M., Cooper, C. B., Ye, Z., Reed, B. R., Moreb, E. A., and Lynch, M. D. (2016) Large-scale bioprocess competitiveness: the potential of dynamic metabolic control in two-stage fermentations Curr. Opin. Chem. Eng. 14, 121-136 10.1016/j.coche.2016.09.008
    • (2016) Curr. Opin. Chem. Eng. , vol.14 , pp. 121-136
    • Burg, J.M.1    Cooper, C.B.2    Ye, Z.3    Reed, B.R.4    Moreb, E.A.5    Lynch, M.D.6
  • 2
    • 84958119733 scopus 로고    scopus 로고
    • Biotechnology for chemical production: Challenges and opportunities
    • Burk, M. J. and Van Dien, S. (2016) Biotechnology for chemical production: challenges and opportunities Trends Biotechnol. 34, 187-90 10.1016/j.tibtech.2015.10.007
    • (2016) Trends Biotechnol. , vol.34 , pp. 187-190
    • Burk, M.J.1    Van Dien, S.2
  • 3
    • 39749134281 scopus 로고    scopus 로고
    • Energy: Not your father's biofuels
    • Tollefson, J. (2008) Energy: not your father's biofuels Nature 451, 880-3 10.1038/451880a
    • (2008) Nature , vol.451 , pp. 880-883
    • Tollefson, J.1
  • 4
    • 72049131519 scopus 로고    scopus 로고
    • Production of first and second generation biofuels: A comprehensive review
    • Naik, S. N., Goud, V. V., Rout, P. K., and Dalai, A. K. (2010) Production of first and second generation biofuels: a comprehensive review Renewable Sustainable Energy Rev. 14, 578-597 10.1016/j.rser.2009.10.003
    • (2010) Renewable Sustainable Energy Rev. , vol.14 , pp. 578-597
    • Naik, S.N.1    Goud, V.V.2    Rout, P.K.3    Dalai, A.K.4
  • 5
    • 79959386497 scopus 로고    scopus 로고
    • Deconstruction of lignocellulosic biomass to fuels and chemicals
    • Chundawat, S. P., Beckham, G. T., Himmel, M. E., and Dale, B. E. (2011) Deconstruction of lignocellulosic biomass to fuels and chemicals Annu. Rev. Chem. Biomol. Eng. 2, 121-45 10.1146/annurev-chembioeng-061010-114205
    • (2011) Annu. Rev. Chem. Biomol. Eng. , vol.2 , pp. 121-145
    • Chundawat, S.P.1    Beckham, G.T.2    Himmel, M.E.3    Dale, B.E.4
  • 6
    • 79957641693 scopus 로고    scopus 로고
    • Second generation biofuels: Economics and policies
    • Carriquiry, M. A., Du, X., and Timilsina, G. R. (2011) Second generation biofuels: Economics and policies Energy Policy 39, 4222-34 10.1016/j.enpol.2011.04.036
    • (2011) Energy Policy , vol.39 , pp. 4222-4234
    • Carriquiry, M.A.1    Du, X.2    Timilsina, G.R.3
  • 8
    • 84884301231 scopus 로고    scopus 로고
    • Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes
    • Bar-Even, A., Noor, E., Flamholz, A., and Milo, R. (2013) Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes Biochim. Biophys. Acta, Bioenerg. 1827, 1039-47 10.1016/j.bbabio.2012.10.013
    • (2013) Biochim. Biophys. Acta, Bioenerg. , vol.1827 , pp. 1039-1047
    • Bar-Even, A.1    Noor, E.2    Flamholz, A.3    Milo, R.4
  • 9
    • 84979503665 scopus 로고    scopus 로고
    • Formate Assimilation: The metabolic architecture of natural and synthetic pathways
    • Bar-Even, A. (2016) Formate Assimilation: The metabolic architecture of natural and synthetic pathways Biochemistry 55, 3851-63 10.1021/acs.biochem.6b00495
    • (2016) Biochemistry , vol.55 , pp. 3851-3863
    • Bar-Even, A.1
  • 10
    • 80052956695 scopus 로고    scopus 로고
    • The electrochemical reduction of carbon dioxide to formate/formic acid: Engineering and economic feasibility
    • Agarwal, A. S., Zhai, Y., Hill, D., and Sridhar, N. (2011) The electrochemical reduction of carbon dioxide to formate/formic acid: engineering and economic feasibility ChemSusChem 4, 1301-10 10.1002/cssc.201100220
    • (2011) ChemSusChem , vol.4 , pp. 1301-1310
    • Agarwal, A.S.1    Zhai, Y.2    Hill, D.3    Sridhar, N.4
  • 12
    • 84912051600 scopus 로고    scopus 로고
    • Fabrication of a novel tin gas diffusion electrode for electrochemical reduction of carbon dioxide to formic acid
    • Wang, Q., Dong, H., and Yu, H. (2014) Fabrication of a novel tin gas diffusion electrode for electrochemical reduction of carbon dioxide to formic acid RSC Adv. 4, 59970-59976 10.1039/C4RA10775F
    • (2014) RSC Adv. , vol.4 , pp. 59970-59976
    • Wang, Q.1    Dong, H.2    Yu, H.3
  • 13
    • 84912027334 scopus 로고    scopus 로고
    • Electrochemical reduction of carbon dioxide to formic acid
    • Lu, X., Leung, D. Y., Wang, H., Leung, M. K., and Xuan, J. (2014) Electrochemical reduction of carbon dioxide to formic acid ChemElectroChem 1, 836-849 10.1002/celc.201300206
    • (2014) ChemElectroChem , vol.1 , pp. 836-849
    • Lu, X.1    Leung, D.Y.2    Wang, H.3    Leung, M.K.4    Xuan, J.5
  • 14
    • 84946221686 scopus 로고    scopus 로고
    • The cathodic reduction of carbon dioxide - What can it realistically achieve? A mini review
    • Pletcher, D. (2015) The cathodic reduction of carbon dioxide-What can it realistically achieve? A mini review Electrochem. Commun. 61, 97-101 10.1016/j.elecom.2015.10.006
    • (2015) Electrochem. Commun. , vol.61 , pp. 97-101
    • Pletcher, D.1
  • 15
  • 16
    • 84866851056 scopus 로고    scopus 로고
    • 2 reduction with high turnover frequency and selectivity of formic acid formation using Ru(II) multinuclear complexes
    • 2 reduction with high turnover frequency and selectivity of formic acid formation using Ru(II) multinuclear complexes Proc. Natl. Acad. Sci. U. S. A. 109, 15673-8 10.1073/pnas.1118336109
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 15673-15678
    • Tamaki, Y.1    Morimoto, T.2    Koike, K.3    Ishitani, O.4
  • 18
    • 58149147646 scopus 로고    scopus 로고
    • Carbon dioxide - The hydrogen-storage material of the future?
    • Enthaler, S. (2008) Carbon dioxide-The hydrogen-storage material of the future? ChemSusChem 1, 801-804 10.1002/cssc.200800101
    • (2008) ChemSusChem , vol.1 , pp. 801-804
    • Enthaler, S.1
  • 19
    • 80053517225 scopus 로고    scopus 로고
    • Selective catalytic conversion of biobased carbohydrates to formic acid using molecular oxygen
    • Wölfel, R., Taccardi, N., Bösmann, A., and Wasserscheid, P. (2011) Selective catalytic conversion of biobased carbohydrates to formic acid using molecular oxygen Green Chem. 13, 2759-2763 10.1039/c1gc15434f
    • (2011) Green Chem. , vol.13 , pp. 2759-2763
    • Wölfel, R.1    Taccardi, N.2    Bösmann, A.3    Wasserscheid, P.4
  • 20
    • 84890830310 scopus 로고    scopus 로고
    • Spectroscopic and electrochemical characterization of heteropoly acids for their optimized application in selective biomass oxidation to formic acid
    • Albert, J., Lüders, D., Bösmann, A., Guldi, D. M., and Wasserscheid, P. (2014) Spectroscopic and electrochemical characterization of heteropoly acids for their optimized application in selective biomass oxidation to formic acid Green Chem. 16, 226-237 10.1039/C3GC41320A
    • (2014) Green Chem. , vol.16 , pp. 226-237
    • Albert, J.1    Lüders, D.2    Bösmann, A.3    Guldi, D.M.4    Wasserscheid, P.5
  • 21
    • 84863109242 scopus 로고    scopus 로고
    • Selective oxidation of complex, water-insoluble biomass to formic acid using additives as reaction accelerators
    • Albert, J., Wölfel, R., Bösmann, A., and Wasserscheid, P. (2012) Selective oxidation of complex, water-insoluble biomass to formic acid using additives as reaction accelerators Energy Environ. Sci. 5, 7956-7962 10.1039/c2ee21428h
    • (2012) Energy Environ. Sci. , vol.5 , pp. 7956-7962
    • Albert, J.1    Wölfel, R.2    Bösmann, A.3    Wasserscheid, P.4
  • 23
    • 24644436313 scopus 로고    scopus 로고
    • A novel effective hydration of carbon monoxide in liquid phase by a water-soluble ruthenium complex catalyst at moderate pressures in aqueous medium
    • Shukla, R. S., Bhatt, S. D., Thorat, R. B., and Jasra, R. V. (2005) A novel effective hydration of carbon monoxide in liquid phase by a water-soluble ruthenium complex catalyst at moderate pressures in aqueous medium Appl. Catal., A 294, 111-118 10.1016/j.apcata.2005.07.034
    • (2005) Appl. Catal., A , vol.294 , pp. 111-118
    • Shukla, R.S.1    Bhatt, S.D.2    Thorat, R.B.3    Jasra, R.V.4
  • 24
    • 84922595387 scopus 로고    scopus 로고
    • Kinetic and stoichiometric characterization of organoautotrophic growth of Ralstonia eutropha on formic acid in fed-batch and continuous cultures
    • Grunwald, S., Mottet, A., Grousseau, E., Plassmeier, J. K., Popovic, M. K., Uribelarrea, J. L., Gorret, N., Guillouet, S. E., and Sinskey, A. (2015) Kinetic and stoichiometric characterization of organoautotrophic growth of Ralstonia eutropha on formic acid in fed-batch and continuous cultures Microb. Biotechnol. 8, 155-63 10.1111/1751-7915.12149
    • (2015) Microb. Biotechnol. , vol.8 , pp. 155-163
    • Grunwald, S.1    Mottet, A.2    Grousseau, E.3    Plassmeier, J.K.4    Popovic, M.K.5    Uribelarrea, J.L.6    Gorret, N.7    Guillouet, S.E.8    Sinskey, A.9
  • 25
    • 84863630261 scopus 로고    scopus 로고
    • Pathway engineering and synthetic biology using acetogens
    • Schiel-Bengelsdorf, B. and Durre, P. (2012) Pathway engineering and synthetic biology using acetogens FEBS Lett. 586, 2191-8 10.1016/j.febslet.2012.04.043
    • (2012) FEBS Lett. , vol.586 , pp. 2191-2198
    • Schiel-Bengelsdorf, B.1    Durre, P.2
  • 26
    • 84961885159 scopus 로고    scopus 로고
    • A thermochemical-biochemical hybrid processing of lignocellulosic biomass for producing fuels and chemicals
    • Shen, Y., Jarboe, L., Brown, R., and Wen, Z. (2015) A thermochemical-biochemical hybrid processing of lignocellulosic biomass for producing fuels and chemicals Biotechnol. Adv. 33, 1799-813 10.1016/j.biotechadv.2015.10.006
    • (2015) Biotechnol. Adv. , vol.33 , pp. 1799-1813
    • Shen, Y.1    Jarboe, L.2    Brown, R.3    Wen, Z.4
  • 27
    • 58849109320 scopus 로고    scopus 로고
    • Methanol-based industrial biotechnology: Current status and future perspectives of methylotrophic bacteria
    • Schrader, J., Schilling, M., Holtmann, D., Sell, D., Filho, M. V., Marx, A., and Vorholt, J. A. (2009) Methanol-based industrial biotechnology: current status and future perspectives of methylotrophic bacteria Trends Biotechnol. 27, 107-15 10.1016/j.tibtech.2008.10.009
    • (2009) Trends Biotechnol. , vol.27 , pp. 107-115
    • Schrader, J.1    Schilling, M.2    Holtmann, D.3    Sell, D.4    Filho, M.V.5    Marx, A.6    Vorholt, J.A.7
  • 28
    • 84867660750 scopus 로고    scopus 로고
    • Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network
    • Kim, J. and Copley, S. D. (2012) Inhibitory cross-talk upon introduction of a new metabolic pathway into an existing metabolic network Proc. Natl. Acad. Sci. U. S. A. 109, E2856-64 10.1073/pnas.1208509109
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. E2856-E2864
    • Kim, J.1    Copley, S.D.2
  • 29
    • 84921739011 scopus 로고    scopus 로고
    • One-carbon metabolic pathway rewiring in Escherichia coli reveals an evolutionary advantage of 10-formyltetrahydrofolate synthetase (Fhs) in survival under hypoxia
    • Sah, S., Aluri, S., Rex, K., and Varshney, U. (2015) One-carbon metabolic pathway rewiring in Escherichia coli reveals an evolutionary advantage of 10-formyltetrahydrofolate synthetase (Fhs) in survival under hypoxia J. Bacteriol. 197, 717-26 10.1128/JB.02365-14
    • (2015) J. Bacteriol. , vol.197 , pp. 717-726
    • Sah, S.1    Aluri, S.2    Rex, K.3    Varshney, U.4
  • 30
    • 0017905126 scopus 로고
    • A complex of N5,N10-methylenetetrahydrofolate dehydrogenase and N5,N10-methenyltetrahydrofolate cyclohydrolase in Escherichia coli. Purification, subunit structure, and allosteric inhibition by N10-formyltetrahydrofolate
    • Dev, I. K. and Harvey, R. J. (1978) A complex of N5,N10-methylenetetrahydrofolate dehydrogenase and N5,N10-methenyltetrahydrofolate cyclohydrolase in Escherichia coli. Purification, subunit structure, and allosteric inhibition by N10-formyltetrahydrofolate J. Biol. Chem. 253, 4245-53
    • (1978) J. Biol. Chem. , vol.253 , pp. 4245-4253
    • Dev, I.K.1    Harvey, R.J.2
  • 31
    • 0034664991 scopus 로고    scopus 로고
    • Tetrahydrofolate and tetrahydromethanopterin compared: Functionally distinct carriers in C1 metabolism
    • Maden, B. E. (2000) Tetrahydrofolate and tetrahydromethanopterin compared: functionally distinct carriers in C1 metabolism Biochem. J. 350 (Pt 3) 609-29 10.1042/bj3500609
    • (2000) Biochem. J. , vol.350 , pp. 609-629
    • Maden, B.E.1
  • 33
    • 0344235395 scopus 로고    scopus 로고
    • Purification of the formate-tetrahydrofolate ligase from Methylobacterium extorquens AM1 and demonstration of its requirement for methylotrophic growth
    • Marx, C. J., Laukel, M., Vorholt, J. A., and Lidstrom, M. E. (2003) Purification of the formate-tetrahydrofolate ligase from Methylobacterium extorquens AM1 and demonstration of its requirement for methylotrophic growth J. Bacteriol. 185, 7169-75 10.1128/JB.185.24.7169-7175.2003
    • (2003) J. Bacteriol. , vol.185 , pp. 7169-7175
    • Marx, C.J.1    Laukel, M.2    Vorholt, J.A.3    Lidstrom, M.E.4
  • 34
    • 0016739935 scopus 로고
    • Derivation of glycine from threonine in Escherichia coli K-12 mutants
    • Fraser, J. and Newman, E. B. (1975) Derivation of glycine from threonine in Escherichia coli K-12 mutants J. Bacteriol. 122, 810-7
    • (1975) J. Bacteriol. , vol.122 , pp. 810-817
    • Fraser, J.1    Newman, E.B.2
  • 36
    • 0025063286 scopus 로고
    • A radical-chemical route to acetyl-CoA: The anaerobically induced pyruvate formate-lyase system of Escherichia coli
    • Knappe, J. and Sawers, G. (1990) A radical-chemical route to acetyl-CoA: the anaerobically induced pyruvate formate-lyase system of Escherichia coli FEMS Microbiol. Lett. 6, 383-98 10.1111/j.1574-6968.1990.tb04108.x
    • (1990) FEMS Microbiol. Lett. , vol.6 , pp. 383-398
    • Knappe, J.1    Sawers, G.2
  • 37
    • 85010908796 scopus 로고    scopus 로고
    • Synthetic metabolism: Metabolic engineering meets enzyme design
    • Erb, T. J., Jones, P. R., and Bar-Even, A. (2017) Synthetic metabolism: metabolic engineering meets enzyme design Curr. Opin. Chem. Biol. 37, 56-62 10.1016/j.cbpa.2016.12.023
    • (2017) Curr. Opin. Chem. Biol. , vol.37 , pp. 56-62
    • Erb, T.J.1    Jones, P.R.2    Bar-Even, A.3
  • 38
    • 79958097953 scopus 로고    scopus 로고
    • The moderately efficient enzyme: Evolutionary and physicochemical trends shaping enzyme parameters
    • Bar-Even, A., Noor, E., Savir, Y., Liebermeister, W., Davidi, D., Tawfik, D. S., and Milo, R. (2011) The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters Biochemistry 50, 4402-10 10.1021/bi2002289
    • (2011) Biochemistry , vol.50 , pp. 4402-4410
    • Bar-Even, A.1    Noor, E.2    Savir, Y.3    Liebermeister, W.4    Davidi, D.5    Tawfik, D.S.6    Milo, R.7
  • 40
    • 84940453195 scopus 로고    scopus 로고
    • Mechanistic analysis of an engineered enzyme that catalyzes the formose reaction
    • Poust, S., Piety, J., Bar-Even, A., Louw, C., Baker, D., Keasling, J. D., and Siegel, J. B. (2015) Mechanistic analysis of an engineered enzyme that catalyzes the formose reaction ChemBioChem 16, 1950 10.1002/cbic.201500228
    • (2015) ChemBioChem , vol.16 , pp. 1950
    • Poust, S.1    Piety, J.2    Bar-Even, A.3    Louw, C.4    Baker, D.5    Keasling, J.D.6    Siegel, J.B.7
  • 41
    • 47249109471 scopus 로고    scopus 로고
    • Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1
    • Crowther, G. J., Kosaly, G., and Lidstrom, M. E. (2008) Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1 J. Bacteriol. 190, 5057-62 10.1128/JB.00228-08
    • (2008) J. Bacteriol. , vol.190 , pp. 5057-5062
    • Crowther, G.J.1    Kosaly, G.2    Lidstrom, M.E.3
  • 43
    • 84861422324 scopus 로고    scopus 로고
    • Rethinking glycolysis: On the biochemical logic of metabolic pathways
    • Bar-Even, A., Flamholz, A., Noor, E., and Milo, R. (2012) Rethinking glycolysis: on the biochemical logic of metabolic pathways Nat. Chem. Biol. 8, 509-517 10.1038/nchembio.971
    • (2012) Nat. Chem. Biol. , vol.8 , pp. 509-517
    • Bar-Even, A.1    Flamholz, A.2    Noor, E.3    Milo, R.4
  • 44
    • 84957797993 scopus 로고    scopus 로고
    • Into new territory: Improved microbial synthesis through engineering of the essential metabolic network
    • Lynch, M. D. (2016) Into new territory: improved microbial synthesis through engineering of the essential metabolic network Curr. Opin. Biotechnol. 38, 106-11 10.1016/j.copbio.2016.01.009
    • (2016) Curr. Opin. Biotechnol. , vol.38 , pp. 106-111
    • Lynch, M.D.1
  • 45
    • 23144444226 scopus 로고    scopus 로고
    • JCat: A novel tool to adapt codon usage of a target gene to its potential expression host
    • Grote, A., Hiller, K., Scheer, M., Munch, R., Nortemann, B., Hempel, D. C., and Jahn, D. (2005) JCat: a novel tool to adapt codon usage of a target gene to its potential expression host Nucleic Acids Res. 33, W526-31 10.1093/nar/gki376
    • (2005) Nucleic Acids Res. , vol.33 , pp. W526-W531
    • Grote, A.1    Hiller, K.2    Scheer, M.3    Munch, R.4    Nortemann, B.5    Hempel, D.C.6    Jahn, D.7
  • 47
    • 0030861452 scopus 로고    scopus 로고
    • Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
    • Lutz, R. and Bujard, H. (1997) Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements Nucleic Acids Res. 25, 1203-10 10.1093/nar/25.6.1203
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1203-1210
    • Lutz, R.1    Bujard, H.2
  • 48
    • 54349084011 scopus 로고    scopus 로고
    • Escherichia coli strains with promoter libraries constructed by Red/ET recombination pave the way for transcriptional fine-tuning
    • Braatsch, S., Helmark, S., Kranz, H., Koebmann, B., and Jensen, P. R. (2008) Escherichia coli strains with promoter libraries constructed by Red/ET recombination pave the way for transcriptional fine-tuning BioTechniques 45, 335-7 10.2144/000112907
    • (2008) BioTechniques , vol.45 , pp. 335-337
    • Braatsch, S.1    Helmark, S.2    Kranz, H.3    Koebmann, B.4    Jensen, P.R.5
  • 49
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
    • Datsenko, K. A. and Wanner, B. L. (2000) One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products Proc. Natl. Acad. Sci. U. S. A. 97, 6640-5 10.1073/pnas.120163297
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 52
    • 84555189111 scopus 로고    scopus 로고
    • Direct analysis of underivatized amino acids in plant extracts by LC-MS-MS
    • Thiele, B., Stein, N., Oldiges, M., and Hofmann, D. (2012) Direct analysis of underivatized amino acids in plant extracts by LC-MS-MS Methods Mol. Biol. 828, 317-28 10.1007/978-1-61779-445-2-25
    • (2012) Methods Mol. Biol. , vol.828 , pp. 317-328
    • Thiele, B.1    Stein, N.2    Oldiges, M.3    Hofmann, D.4
  • 53
    • 80054061389 scopus 로고    scopus 로고
    • Elemental formula annotation of polar and lipophilic metabolites using (13) C, (15) N and (34) S isotope labelling, in combination with high-resolution mass spectrometry
    • Giavalisco, P., Li, Y., Matthes, A., Eckhardt, A., Hubberten, H. M., Hesse, H., Segu, S., Hummel, J., Kohl, K., and Willmitzer, L. (2011) Elemental formula annotation of polar and lipophilic metabolites using (13) C, (15) N and (34) S isotope labelling, in combination with high-resolution mass spectrometry Plant J. 68, 364-76 10.1111/j.1365-313X.2011.04682.x
    • (2011) Plant J. , vol.68 , pp. 364-376
    • Giavalisco, P.1    Li, Y.2    Matthes, A.3    Eckhardt, A.4    Hubberten, H.M.5    Hesse, H.6    Segu, S.7    Hummel, J.8    Kohl, K.9    Willmitzer, L.10
  • 54
    • 84934300609 scopus 로고    scopus 로고
    • Chemical reactivity drives spatiotemporal organisation of bacterial metabolism
    • de Lorenzo, V., Sekowska, A., and Danchin, A. (2014) Chemical reactivity drives spatiotemporal organisation of bacterial metabolism FEMS Microbiol. Rev. 39, 96-119 10.1111/1574-6976.12089
    • (2014) FEMS Microbiol. Rev. , vol.39 , pp. 96-119
    • De Lorenzo, V.1    Sekowska, A.2    Danchin, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.