메뉴 건너뛰기




Volumn 68, Issue 2, 2011, Pages 364-376

Elemental formula annotation of polar and lipophilic metabolites using 13C, 15N and 34S isotope labelling, in combination with high-resolution mass spectrometry

Author keywords

Arabidopsis thaliana; isotope labelling; mass spectrometry; metabolomics; proteomics

Indexed keywords

ARABIDOPSIS THALIANA; COMPREHENSIVE ANALYSIS; ELEMENTAL COMPOSITIONS; ELEMENTAL FORMULA; EXTRACTION PROCEDURE; HIGH RESOLUTION; HIGH RESOLUTION MASS SPECTROMETRY; ISOTOPE LABELLING; LIPIDOMES; LIPOPHILIC METABOLITES; METABOLITE EXTRACTION; METABOLOMES; METABOLOMICS; PLANT TISSUES; PROOF OF CONCEPT; PROTEOMICS; ROOT EXTRACTS; SELECTED EXAMPLES;

EID: 80054061389     PISSN: 09607412     EISSN: 1365313X     Source Type: Journal    
DOI: 10.1111/j.1365-313X.2011.04682.x     Document Type: Article
Times cited : (272)

References (62)
  • 1
    • 73349121270 scopus 로고    scopus 로고
    • An introduction to liquid chromatography-mass spectrometry instrumentation applied in plant metabolomic analyses
    • Allwood, J.W., and, Goodacre, R., (2010) An introduction to liquid chromatography-mass spectrometry instrumentation applied in plant metabolomic analyses. Phytochem. Anal. 21, 33-47.
    • (2010) Phytochem. Anal. , vol.21 , pp. 33-47
    • Allwood, J.W.1    Goodacre, R.2
  • 2
    • 68949091826 scopus 로고    scopus 로고
    • Plant PA signaling via diacylglycerol kinase
    • Arisz, S.A., Testerink, C., and, Munnik, T., (2009) Plant PA signaling via diacylglycerol kinase. Biochim. Biophys. Acta, 1791, 869-875.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 869-875
    • Arisz, S.A.1    Testerink, C.2    Munnik, T.3
  • 3
    • 69249103778 scopus 로고    scopus 로고
    • Use of reverse-phase liquid chromatography, linked to tandem mass spectrometry, to profile the Calvin cycle and other metabolic intermediates in Arabidopsis rosettes at different carbon dioxide concentrations
    • Arrivault, S., Guenther, M., Ivakov, A., Feil, R., Vosloh, D., van Dongen, J.T., Sulpice, R., and, Stitt, M., (2009) Use of reverse-phase liquid chromatography, linked to tandem mass spectrometry, to profile the Calvin cycle and other metabolic intermediates in Arabidopsis rosettes at different carbon dioxide concentrations. Plant J. 59, 826-839.
    • (2009) Plant J. , vol.59 , pp. 826-839
    • Arrivault, S.1    Guenther, M.2    Ivakov, A.3    Feil, R.4    Vosloh, D.5    Van Dongen, J.T.6    Sulpice, R.7    Stitt, M.8
  • 4
    • 55749095402 scopus 로고    scopus 로고
    • The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development
    • Bach, L., Michaelson, L.V., Haslam, R., et al. (2008) The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development. Proc. Natl Acad. Sci. USA, 105, 14727-14731.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 14727-14731
    • Bach, L.1    Michaelson, L.V.2    Haslam, R.3
  • 5
    • 77957230413 scopus 로고    scopus 로고
    • Correction of mass calibration gaps in liquid chromatography-mass spectrometry metabolomics data
    • Benton, H.P., Want, E.J., and, Ebbels, T.M., (2010) Correction of mass calibration gaps in liquid chromatography-mass spectrometry metabolomics data. Bioinformatics, 26, 2488-2489.
    • (2010) Bioinformatics , vol.26 , pp. 2488-2489
    • Benton, H.P.1    Want, E.J.2    Ebbels, T.M.3
  • 6
    • 53749101844 scopus 로고    scopus 로고
    • Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in arabidopsis
    • DOI 10.1104/pp.108.117754
    • Bottcher, C., von Roepenack-Lahaye, E., Schmidt, J., Schmotz, C., Neumann, S., Scheel, D., and, Clemens, S., (2008) Metabolome analysis of biosynthetic mutants reveals a diversity of metabolic changes and allows identification of a large number of new compounds in Arabidopsis. Plant Physiol. 147, 2107-2120. (Pubitemid 352844226)
    • (2008) Plant Physiology , vol.147 , Issue.4 , pp. 2107-2120
    • Bottcher, C.1    Von Roepenack-Lahaye, E.2    Schmidt, J.3    Schmotz, C.4    Neumann, S.5    Scheel, D.6    Clemens, S.7
  • 7
    • 33745728711 scopus 로고    scopus 로고
    • MET-IDEA: Data extraction tool for mass spectrometry-based metabolomics
    • Broeckling, C.D., Reddy, I.R., Duran, A.L., Zhao, X., and, Sumner, L.W., (2006) MET-IDEA: data extraction tool for mass spectrometry-based metabolomics. Anal. Chem. 78, 4334-4341.
    • (2006) Anal. Chem. , vol.78 , pp. 4334-4341
    • Broeckling, C.D.1    Reddy, I.R.2    Duran, A.L.3    Zhao, X.4    Sumner, L.W.5
  • 8
    • 0037311116 scopus 로고    scopus 로고
    • Variation of glucosinolate accumulation among different organs and developmental stages of Arabidopsis thaliana
    • DOI 10.1016/S0031-9422(02)00549-6, PII S0031942202005496
    • Brown, P.D., Tokuhisa, J.G., Reichelt, M., and, Gershenzon, J., (2003) Variation of glucosinolate accumulation among different organs and developmental stages of Arabidopsis thaliana. Phytochemistry, 62, 471-481. (Pubitemid 36168949)
    • (2003) Phytochemistry , vol.62 , Issue.3 , pp. 471-481
    • Brown, P.D.1    Tokuhisa, J.G.2    Reichelt, M.3    Gershenzon, J.4
  • 10
    • 18044394444 scopus 로고    scopus 로고
    • The secondary metabolism of Arabidopsis thaliana: Growing like a weed
    • DOI 10.1016/j.pbi.2005.03.012
    • D'Auria, J.C., and, Gershenzon, J., (2005) The secondary metabolism of Arabidopsis thaliana: growing like a weed. Curr. Opin. Plant Biol. 8, 308-316. (Pubitemid 40599984)
    • (2005) Current Opinion in Plant Biology , vol.8 , Issue.3 SPEC. ISS. , pp. 308-316
    • D'Auria, J.C.1    Gershenzon, J.2
  • 11
    • 34248512719 scopus 로고    scopus 로고
    • Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry
    • DOI 10.1038/nprot.2007.95, PII NPROT.2007.95
    • De Vos, R.C., Moco, S., Lommen, A., Keurentjes, J.J., Bino, R.J., and, Hall, R.D., (2007) Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry. Nat. Protoc. 2, 778-791. (Pubitemid 46745574)
    • (2007) Nature Protocols , vol.2 , Issue.4 , pp. 778-791
    • De Vos, R.C.H.1    Moco, S.2    Lommen, A.3    Keurentjes, J.J.B.4    Bino, R.J.5    Hall, R.D.6
  • 12
    • 33846000626 scopus 로고    scopus 로고
    • Mass spectrometry-based metabolomics
    • DOI 10.1002/mas.20108
    • Dettmer, K., Aronov, P.A., and, Hammock, B.D., (2007) Mass spectrometry-based metabolomics. Mass Spectrom. Rev. 26, 51-78. (Pubitemid 46051813)
    • (2007) Mass Spectrometry Reviews , vol.26 , Issue.1 , pp. 51-78
    • Dettmer, K.1    Aronov, P.A.2    Hammock, B.D.3
  • 13
    • 33747871812 scopus 로고    scopus 로고
    • Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a PHOSPHOLIPASE Dα1 knockout mutant
    • DOI 10.1016/j.phytochem.2006.06.005, PII S0031942206003219
    • Devaiah, S.P., Roth, M.R., Baughman, E., Li, M., Tamura, P., Jeannotte, R., Welti, R., and, Wang, X., (2006) Quantitative profiling of polar glycerolipid species from organs of wild-type Arabidopsis and a phospholipase Dalpha1 knockout mutant. Phytochemistry, 67, 1907-1924. (Pubitemid 44291405)
    • (2006) Phytochemistry , vol.67 , Issue.17 , pp. 1907-1924
    • Devaiah, S.P.1    Roth, M.R.2    Baughman, E.3    Li, M.4    Tamura, P.5    Jeannotte, R.6    Welti, R.7    Wang, X.8
  • 14
    • 0036512409 scopus 로고    scopus 로고
    • Galactolipids rule in seed plants
    • DOI 10.1016/S1360-1385(01)02216-6, PII S1360138501022166
    • Dormann, P., and, Benning, C., (2002) Galactolipids rule in seed plants. Trends Plant Sci. 7, 112-118. (Pubitemid 36726436)
    • (2002) Trends in Plant Science , vol.7 , Issue.3 , pp. 112-118
    • Dormann, P.1    Benning, C.2
  • 15
    • 42449122308 scopus 로고    scopus 로고
    • Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes
    • Dunn, W.B., (2008) Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes. Phys. Biol. 5, 011001.
    • (2008) Phys. Biol. , vol.5 , pp. 011001
    • Dunn, W.B.1
  • 16
    • 36549081975 scopus 로고    scopus 로고
    • Advances of high-resolution NMR techniques in the structural and metabolic analysis of plant biochemistry
    • DOI 10.1016/j.phytochem.2007.09.028, PII S0031942207005729, Highlights in the Evolution of Phytochemistry: 50 Years of the Phytochemical Society of Europe
    • Eisenreich, W., and, Bacher, A., (2007) Advances of high-resolution NMR techniques in the structural and metabolic analysis of plant biochemistry. Phytochemistry, 68, 2799-2815. (Pubitemid 350180954)
    • (2007) Phytochemistry , vol.68 , Issue.22-24 , pp. 2799-2815
    • Eisenreich, W.1    Bacher, A.2
  • 18
    • 0034470049 scopus 로고    scopus 로고
    • Does triacylglycerol biosynthesis require diacylglycerol acyltransferase (DAGAT)?
    • DOI 10.1042/0300-5127:0280698
    • Fraser, T., Waters, A., Chatrattanakunchai, S., and, Stobart, K., (2000) Does triacylglycerol biosynthesis require diacylglycerol acyltransferase (DAGAT)? Biochem. Soc. Trans. 28, 698-700. (Pubitemid 32163236)
    • (2000) Biochemical Society Transactions , vol.28 , Issue.6 , pp. 698-700
    • Fraser, T.1    Waters, A.2    Chatrattanakunchai, S.3    Stobart, K.4
  • 19
    • 45749099688 scopus 로고    scopus 로고
    • Metabonomics in cancer diagnosis: Mass spectrometry-based profiling of urinary nucleosides from breast cancer patients
    • DOI 10.1080/13547500802012858, PII 791845894
    • Frickenschmidt, A., Frohlich, H., Bullinger, D., Zell, A., Laufer, S., Gleiter, C.H., Liebich, H., and, Kammerer, B., (2008) Metabonomics in cancer diagnosis: mass spectrometry-based profiling of urinary nucleosides from breast cancer patients. Biomarkers, 13, 435-449. (Pubitemid 351865818)
    • (2008) Biomarkers , vol.13 , Issue.4 , pp. 435-449
    • Frickenschmidt, A.1    Frohlich, H.2    Bullinger, D.3    Zell, A.4    Laufer, S.5    Gleiter, C.H.6    Liebich, H.7    Kammerer, B.8
  • 20
    • 58149110910 scopus 로고    scopus 로고
    • High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas
    • Giavalisco, P., Hummel, J., Lisec, J., Inostroza, A.C., Catchpole, G., and, Willmitzer, L., (2008) High-resolution direct infusion-based mass spectrometry in combination with whole 13C metabolome isotope labeling allows unambiguous assignment of chemical sum formulas. Anal. Chem. 80, 9417-9425.
    • (2008) Anal. Chem. , vol.80 , pp. 9417-9425
    • Giavalisco, P.1    Hummel, J.2    Lisec, J.3    Inostroza, A.C.4    Catchpole, G.5    Willmitzer, L.6
  • 21
    • 68049083650 scopus 로고    scopus 로고
    • 13C isotope-labeled metabolomes allowing for improved compound annotation and relative quantification in liquid chromatography-mass spectrometry-based metabolomic research
    • Giavalisco, P., Kohl, K., Hummel, J., Seiwert, B., and, Willmitzer, L., (2009) 13C isotope-labeled metabolomes allowing for improved compound annotation and relative quantification in liquid chromatography-mass spectrometry-based metabolomic research. Anal. Chem. 81, 6546-6551.
    • (2009) Anal. Chem. , vol.81 , pp. 6546-6551
    • Giavalisco, P.1    Kohl, K.2    Hummel, J.3    Seiwert, B.4    Willmitzer, L.5
  • 22
    • 47749121066 scopus 로고    scopus 로고
    • Spatial and temporal dynamics of jasmonate synthesis and accumulation in Arabidopsis in response to wounding
    • Glauser, G., Grata, E., Dubugnon, L., Rudaz, S., Farmer, E.E., and, Wolfender, J.L., (2008) Spatial and temporal dynamics of jasmonate synthesis and accumulation in Arabidopsis in response to wounding. J. Biol. Chem. 283, 16400-16407.
    • (2008) J. Biol. Chem. , vol.283 , pp. 16400-16407
    • Glauser, G.1    Grata, E.2    Dubugnon, L.3    Rudaz, S.4    Farmer, E.E.5    Wolfender, J.L.6
  • 23
    • 33750475205 scopus 로고    scopus 로고
    • Metabolomics-based systems biology and personalized medicine: Moving towards n = 1 clinical trials?
    • DOI 10.2217/14622416.7.7.1087
    • van der Greef, J., Hankemeier, T., and, McBurney, R.N., (2006) Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials? Pharmacogenomics, 7, 1087-1094. (Pubitemid 44644787)
    • (2006) Pharmacogenomics , vol.7 , Issue.7 , pp. 1087-1094
    • Van Der Greef, J.1    Hankemeier, T.2    McBurney, R.N.3
  • 24
    • 68949157005 scopus 로고    scopus 로고
    • Mass spectrometry: From proteomics to metabolomics and lipidomics
    • Griffiths, W.J., and, Wang, Y., (2009) Mass spectrometry: from proteomics to metabolomics and lipidomics. Chem. Soc. Rev. 38, 1882-1896.
    • (2009) Chem. Soc. Rev. , vol.38 , pp. 1882-1896
    • Griffiths, W.J.1    Wang, Y.2
  • 26
    • 34547675713 scopus 로고    scopus 로고
    • 2 labelling
    • DOI 10.1016/j.phytochem.2007.03.026, PII S0031942207002038
    • Huege, J., Sulpice, R., Gibon, Y., Lisec, J., Koehl, K., and, Kopka, J., (2007) GC-EI-TOF-MS analysis of in vivo carbon-partitioning into soluble metabolite pools of higher plants by monitoring isotope dilution after (13)CO(2) labelling. Phytochemistry, 68, 2258-2272. (Pubitemid 47211181)
    • (2007) Phytochemistry , vol.68 , Issue.16-18 , pp. 2258-2272
    • Huege, J.1    Sulpice, R.2    Gibon, Y.3    Lisec, J.4    Koehl, K.5    Kopka, J.6
  • 27
    • 84872000271 scopus 로고    scopus 로고
    • Ultra performance liquid chromatography and high resolution mass spectrometry for the analysis of plant lipids
    • in press.
    • Hummel, J., Segu, S., Li, Y., Irgang, S., Jueppner, J., and, Giavalisco, P., (2011) Ultra performance liquid chromatography and high resolution mass spectrometry for the analysis of plant lipids. Frontiers in Plant Physiology, in press.
    • (2011) Frontiers in Plant Physiology
    • Hummel, J.1    Segu, S.2    Li, Y.3    Irgang, S.4    Jueppner, J.5    Giavalisco, P.6
  • 28
    • 38549126643 scopus 로고    scopus 로고
    • KEGG for linking genomes to life and the environment
    • (supplement 1), D480-D484.
    • Kanehisa, M., Araki, M., Goto, S., et al. (2008) KEGG for linking genomes to life and the environment. Nucleic Acids Res. 36 (supplement 1), D480-D484.
    • (2008) Nucleic Acids Res. , vol.36
    • Kanehisa, M.1    Araki, M.2    Goto, S.3
  • 29
    • 34347405493 scopus 로고    scopus 로고
    • Data processing for mass spectrometry-based metabolomics
    • DOI 10.1016/j.chroma.2007.04.021, PII S0021967307006966, Data Analysis in Chromatography
    • Katajamaa, M., and, Oresic, M., (2007) Data processing for mass spectrometry-based metabolomics. J. Chromatogr. 1158, 318-328. (Pubitemid 47021150)
    • (2007) Journal of Chromatography A , vol.1158 , Issue.1-2 , pp. 318-328
    • Katajamaa, M.1    Oresic, M.2
  • 30
    • 73349090880 scopus 로고    scopus 로고
    • Sample preparation for plant metabolomics
    • Kim, H.K., and, Verpoorte, R., (2010) Sample preparation for plant metabolomics. Phytochem. Anal. 21, 4-13.
    • (2010) Phytochem. Anal. , vol.21 , pp. 4-13
    • Kim, H.K.1    Verpoorte, R.2
  • 31
    • 33646754900 scopus 로고    scopus 로고
    • Metabolomic database annotations via query of elemental compositions: Mass accuracy is insufficient even at less than 1 ppm
    • Kind, T., and, Fiehn, O., (2006) Metabolomic database annotations via query of elemental compositions: mass accuracy is insufficient even at less than 1 ppm. BMC Bioinformatics, 7, 234.
    • (2006) BMC Bioinformatics , vol.7 , pp. 234
    • Kind, T.1    Fiehn, O.2
  • 32
  • 35
    • 34248580879 scopus 로고    scopus 로고
    • Gas chromatography mass spectrometry-based metabolite profiling in plants
    • Lisec, J., Schauer, N., Kopka, J., Willmitzer, L., and, Fernie, A.R., (2006) Gas chromatography mass spectrometry-based metabolite profiling in plants. Nat. Protoc. 1, 387-396.
    • (2006) Nat. Protoc. , vol.1 , pp. 387-396
    • Lisec, J.1    Schauer, N.2    Kopka, J.3    Willmitzer, L.4    Fernie, A.R.5
  • 36
    • 65249132985 scopus 로고    scopus 로고
    • MetAlign: Interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing
    • Lommen, A., (2009) MetAlign: interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing. Anal. Chem. 81, 3079-3086.
    • (2009) Anal. Chem. , vol.81 , pp. 3079-3086
    • Lommen, A.1
  • 37
    • 77951072181 scopus 로고    scopus 로고
    • Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer
    • Lu, W., Clasquin, M.F., Melamud, E., Amador-Noguez, D., Caudy, A.A., and, Rabinowitz, J.D., (2010) Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. Anal. Chem. 82, 3212-3221.
    • (2010) Anal. Chem. , vol.82 , pp. 3212-3221
    • Lu, W.1    Clasquin, M.F.2    Melamud, E.3    Amador-Noguez, D.4    Caudy, A.A.5    Rabinowitz, J.D.6
  • 38
    • 33947732521 scopus 로고    scopus 로고
    • Rapid measurement of sphingolipids from Arabidopsis thaliana by reversed-phase high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry
    • DOI 10.1002/rcm.2962
    • Markham, J.E., and, Jaworski, J.G., (2007) Rapid measurement of sphingolipids from Arabidopsis thaliana by reversed-phase high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 21, 1304-1314. (Pubitemid 46506586)
    • (2007) Rapid Communications in Mass Spectrometry , vol.21 , Issue.7 , pp. 1304-1314
    • Markham, J.E.1    Jaworski, J.G.2
  • 40
    • 70449436059 scopus 로고    scopus 로고
    • Assessment of metabolome annotation quality: A method for evaluating the false discovery rate of elemental composition searches
    • Matsuda, F., Shinbo, Y., Oikawa, A., Hirai, M.Y., Fiehn, O., Kanaya, S., and, Saito, K., (2009a) Assessment of metabolome annotation quality: a method for evaluating the false discovery rate of elemental composition searches. PLoS ONE, 4, e7490.
    • (2009) PLoS ONE , vol.4
    • Matsuda, F.1    Shinbo, Y.2    Oikawa, A.3    Hirai, M.Y.4    Fiehn, O.5    Kanaya, S.6    Saito, K.7
  • 41
    • 58849117570 scopus 로고    scopus 로고
    • MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites
    • Matsuda, F., Yonekura-Sakakibara, K., Niida, R., Kuromori, T., Shinozaki, K., and, Saito, K., (2009b) MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites. Plant J. 57, 555-577.
    • (2009) Plant J. , vol.57 , pp. 555-577
    • Matsuda, F.1    Yonekura-Sakakibara, K.2    Niida, R.3    Kuromori, T.4    Shinozaki, K.5    Saito, K.6
  • 42
    • 50049102248 scopus 로고    scopus 로고
    • Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics
    • Matyash, V., Liebisch, G., Kurzchalia, T.V., Shevchenko, A., and, Schwudke, D., (2008) Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics. J. Lipid Res. 49, 1137-1146.
    • (2008) J. Lipid Res. , vol.49 , pp. 1137-1146
    • Matyash, V.1    Liebisch, G.2    Kurzchalia, T.V.3    Shevchenko, A.4    Schwudke, D.5
  • 43
    • 77950526062 scopus 로고    scopus 로고
    • Involvement of AtNAP1 in the regulation of chlorophyll degradation in Arabidopsis thaliana
    • Nagane, T., Tanaka, A., and, Tanaka, R., (2010) Involvement of AtNAP1 in the regulation of chlorophyll degradation in Arabidopsis thaliana. Planta, 231, 939-949.
    • (2010) Planta , vol.231 , pp. 939-949
    • Nagane, T.1    Tanaka, A.2    Tanaka, R.3
  • 45
    • 71149117622 scopus 로고    scopus 로고
    • Metabolic systems biology
    • Palsson, B., (2009) Metabolic systems biology. FEBS Lett. 583, 3900-3904.
    • (2009) FEBS Lett. , vol.583 , pp. 3900-3904
    • Palsson, B.1
  • 46
    • 33846109344 scopus 로고    scopus 로고
    • Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics
    • DOI 10.1007/s00216-006-0687-8
    • Pan, Z., and, Raftery, D., (2007) Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics. Anal. Bioanal. Chem. 387, 525-527. (Pubitemid 46067468)
    • (2007) Analytical and Bioanalytical Chemistry , vol.387 , Issue.2 , pp. 525-527
    • Pan, Z.1    Raftery, D.2
  • 47
    • 77954772536 scopus 로고    scopus 로고
    • MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data
    • Pluskal, T., Castillo, S., Villar-Briones, A., and, Oresic, M., (2010) MZmine 2: modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data. BMC Bioinformatics, 11, 395.
    • (2010) BMC Bioinformatics , vol.11 , pp. 395
    • Pluskal, T.1    Castillo, S.2    Villar-Briones, A.3    Oresic, M.4
  • 48
    • 34247123157 scopus 로고    scopus 로고
    • Cellular metabolomics of Escherchia coli
    • DOI 10.1586/14789450.4.2.187
    • Rabinowitz, J.D., (2007) Cellular metabolomics of Escherchia coli. Exp. Rev. Proteomics, 4, 187-198. (Pubitemid 46588455)
    • (2007) Expert Review of Proteomics , vol.4 , Issue.2 , pp. 187-198
    • Rabinowitz, J.D.1
  • 49
    • 33847414492 scopus 로고    scopus 로고
    • Novel application of reversed-phase UPLC-oaTOF-MS for lipid analysis in complex biological mixtures: A new tool for lipidomics
    • DOI 10.1021/pr060611b
    • Rainville, P.D., Stumpf, C.L., Shockcor, J.P., Plumb, R.S., and, Nicholson, J.K., (2007) Novel application of reversed-phase UPLC-oaTOF-MS for lipid analysis in complex biological mixtures: a new tool for lipidomics. J. Proteome Res. 6, 552-558. (Pubitemid 46340159)
    • (2007) Journal of Proteome Research , vol.6 , Issue.2 , pp. 552-558
    • Rainville, P.D.1    Stumpf, C.L.2    Shockcor, J.P.3    Plumb, R.S.4    Nicholson, J.K.5
  • 50
    • 77951880802 scopus 로고    scopus 로고
    • Metabolomics for functional genomics, systems biology, and biotechnology
    • Saito, K., and, Matsuda, F., (2010) Metabolomics for functional genomics, systems biology, and biotechnology. Annu. Rev. Plant Biol. 61, 463-489.
    • (2010) Annu. Rev. Plant Biol. , vol.61 , pp. 463-489
    • Saito, K.1    Matsuda, F.2
  • 51
    • 66449128543 scopus 로고    scopus 로고
    • Pheophytin pheophorbide hydrolase (pheophytinase) is involved in chlorophyll breakdown during leaf senescence in Arabidopsis
    • Schelbert, S., Aubry, S., Burla, B., Agne, B., Kessler, F., Krupinska, K., and, Hortensteiner, S., (2009) Pheophytin pheophorbide hydrolase (pheophytinase) is involved in chlorophyll breakdown during leaf senescence in Arabidopsis. Plant Cell, 21, 767-785.
    • (2009) Plant Cell , vol.21 , pp. 767-785
    • Schelbert, S.1    Aubry, S.2    Burla, B.3    Agne, B.4    Kessler, F.5    Krupinska, K.6    Hortensteiner, S.7
  • 54
    • 32444446805 scopus 로고    scopus 로고
    • XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
    • DOI 10.1021/ac051437y
    • Smith, C.A., Want, E.J., O'Maille, G., Abagyan, R., and, Siuzdak, G., (2006) XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal. Chem. 78, 779-787. (Pubitemid 43228585)
    • (2006) Analytical Chemistry , vol.78 , Issue.3 , pp. 779-787
    • Smith, C.A.1    Want, E.J.2    O'Maille, G.3    Abagyan, R.4    Siuzdak, G.5
  • 55
    • 77950811675 scopus 로고    scopus 로고
    • Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies
    • Spagou, K., Tsoukali, H., Raikos, N., Gika, H., Wilson, I.D., and, Theodoridis, G., (2010) Hydrophilic interaction chromatography coupled to MS for metabonomic/metabolomic studies. J. Sep. Sci. 33, 716-727.
    • (2010) J. Sep. Sci. , vol.33 , pp. 716-727
    • Spagou, K.1    Tsoukali, H.2    Raikos, N.3    Gika, H.4    Wilson, I.D.5    Theodoridis, G.6
  • 57
    • 34250663450 scopus 로고    scopus 로고
    • MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis
    • DOI 10.1104/pp.106.091579
    • Textor, S., de Kraker, J.W., Hause, B., Gershenzon, J., and, Tokuhisa, J.G., (2007) MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis. Plant Physiol. 144, 60-71. (Pubitemid 46941605)
    • (2007) Plant Physiology , vol.144 , Issue.1 , pp. 60-71
    • Textor, S.1    De Kraker, J.-W.2    Hause, B.3    Gershenzon, J.4    Tokuhisa, J.G.5
  • 58
    • 62549159971 scopus 로고    scopus 로고
    • Web-based resources for mass-spectrometry-based metabolomics: A user's guide
    • Tohge, T., and, Fernie, A.R., (2009) Web-based resources for mass-spectrometry-based metabolomics: a user's guide. Phytochemistry, 70, 450-456.
    • (2009) Phytochemistry , vol.70 , pp. 450-456
    • Tohge, T.1    Fernie, A.R.2
  • 59
    • 67849104638 scopus 로고    scopus 로고
    • PubChem: A public information system for analyzing bioactivities of small molecules
    • Wang, Y., Xiao, J., Suzek, T.O., Zhang, J., Wang, J., and, Bryant, S.H., (2009) PubChem: a public information system for analyzing bioactivities of small molecules. Nucleic Acids Res. 37, W623-W633.
    • (2009) Nucleic Acids Res. , vol.37
    • Wang, Y.1    Xiao, J.2    Suzek, T.O.3    Zhang, J.4    Wang, J.5    Bryant, S.H.6
  • 60
    • 0942265392 scopus 로고    scopus 로고
    • Process for the integrated extraction, identification and quantification of metabolites, proteins and RNA to reveal their co-regulation in biochemical networks
    • DOI 10.1002/pmic.200200500
    • Weckwerth, W., Wenzel, K., and, Fiehn, O., (2004) Process for the integrated extraction, identification and quantification of metabolites, proteins and RNA to reveal their co-regulation in biochemical networks. Proteomics, 4, 78-83. (Pubitemid 38140876)
    • (2004) Proteomics , vol.4 , Issue.1 , pp. 78-83
    • Weckwerth, W.1    Wenzel, K.2    Fiehn, O.3
  • 62
    • 57749089675 scopus 로고    scopus 로고
    • Comprehensive flavonol profiling and transcriptome coexpression analysis leading to decoding gene-metabolite correlations in Arabidopsis
    • DOI 10.1105/tpc.108.058040
    • Yonekura-Sakakibara, K., Tohge, T., Matsuda, F., Nakabayashi, R., Takayama, H., Niida, R., Watanabe-Takahashi, A., Inoue, E., and, Saito, K., (2008) Comprehensive flavonol profiling and transcriptome coexpression analysis leading to decoding gene-metabolite correlations in Arabidopsis. Plant Cell, 20, 2160-2176. (Pubitemid 352844517)
    • (2008) Plant Cell , vol.20 , Issue.8 , pp. 2160-2176
    • Yonekura-Sakakibara, K.1    Tohge, T.2    Matsuda, F.3    Nakabayashi, R.4    Takayama, H.5    Niida, R.6    Watanabe-Takahashi, A.7    Inoue, E.8    Saito, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.