Computational protein design enables a novel one-carbon assimilation pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 12, 2015, Pages 3704-3709

  Siegel, Justin B ^a,b,c,d   Smith, Amanda Lee ^e   Poust, Sean ^f,g   Wargacki, Adam J ^c   Bar Even, Arren ^h   Louw, Catherine ^c   Shen, Betty W ⁱ   Eiben, Christopher B ^c,f,g   Tran, Huu M ^j   Noor, Elad ^h   Gallaher, Jasmine L ^c   Bale, Jacob ^c,d   Yoshikuni, Yasuo ^c,d,k   Gelb, Michael H ^c,d   Keasling, Jay D ^f,g,k,l   Stoddard, Barry L ⁱ   Lidstrom, Mary E ^d,e   Baker, David ^c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e University of Washington   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g JOINT BIOENERGY INSTITUTE   (United States)

^h WEIZMANN INSTITUTE OF SCIENCE   (Israel)

ⁱ Fred Hutchinson Cancer Research Center   (United States)

^j SANDIA NATIONAL LABORATORIES   (United States)

^k LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^l Synthetic Biology Engineering Research Center   (United States)

more..

Author keywords

Carbon fixation; Computational protein design; Pathway engineering

Indexed keywords

CARBON; DIHYDROXYACETONE; DIHYDROXYACETONE PHOSPHATE; ENZYME; FORMIC ACID; FORMOLASE; UNCLASSIFIED DRUG; FORMALDEHYDE; FORMIC ACID DERIVATIVE; PROTEIN;

ARTICLE; BIOSYNTHESIS; CARBON FIXATION; CARBON METABOLISM; CARBON UTILIZATION; CATALYST; COMPUTATIONAL PROTEIN DESIGN; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME ENGINEERING; METABOLITE; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; BIOMASS; CARBON CYCLE; CATALYSIS; CHEMISTRY; COMPUTER PROGRAM; ENZYMOLOGY; ESCHERICHIA COLI; MOLECULAR CLONING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYMERASE CHAIN REACTION; PROCEDURES; PROTEIN ENGINEERING; THERMODYNAMICS;

BIOMASS; BIOSYNTHETIC PATHWAYS; CARBON; CARBON CYCLE; CATALYSIS; CLONING, MOLECULAR; ESCHERICHIA COLI; FORMALDEHYDE; FORMATES; MAGNETIC RESONANCE SPECTROSCOPY; POLYMERASE CHAIN REACTION; PROTEIN ENGINEERING; PROTEINS; SOFTWARE; THERMODYNAMICS;

EID: 84925426233     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1500545112     Document Type: Article

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