Highly efficient base editing in human tripronuclear zygotes

Protein and Cell

Volumn 8, Issue 10, 2017, Pages 772-775

  Zhou, Changyang ^a,b   Zhang, Meiling ^c   Wei, Yu ^a   Sun, Yidi ^b,e,f,g   Sun, Yun ^c   Pan, Hong ^a,h   Yao, Ning ^c   Zhong, Wanxia ^c   Li, Yixue ^b,e,f,g   Li, Weiping ^c   Yang, Hui ^a   Chen, Zi jiang ^c,d  

^a Shenzhen Fundamental Research Institutions   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^e Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^f FUDAN UNIVERSITY   (China)

^g SHANGHAI CENTER FOR BIOINFORMATION TECHNOLOGY   (China)

^h GUANGXI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; DNA METHYLTRANSFERASE 3B; URACIL DNA GLYCOSIDASE; APOBEC1 PROTEIN, HUMAN; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; HEMOGLOBIN BETA CHAIN;

BLASTOMA; CRISPR CAS SYSTEM; DNA MODIFICATION; GENE AMPLIFICATION; GENE EDITING; GENE MUTATION; GENETIC ANALYSIS; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN EMBRYO; LETTER; MUTATION RATE; NONHUMAN; NONSENSE MUTATION; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SANGER SEQUENCING; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE GENOME SEQUENCING; ZYGOTE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; PROCEDURES; STOP CODON;

APOBEC-1 DEAMINASE; BETA-GLOBINS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CODON, TERMINATOR; GENE EDITING; HUMANS; ZYGOTE;

EID: 85028968798     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-017-0459-6     Document Type: Letter

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