-
1
-
-
33746338535
-
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans
-
M. G. Roncarolo, S. Gregori, M. Battaglia, R. Bacchetta, K. Fleischhauer, M. K. Levings, Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol. Rev. 212, 28–50 (2006).
-
(2006)
Immunol. Rev.
, vol.212
, pp. 28-50
-
-
Roncarolo, M.G.1
Gregori, S.2
Battaglia, M.3
Bacchetta, R.4
Fleischhauer, K.5
Levings, M.K.6
-
2
-
-
0028158319
-
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells
-
R. Bacchetta, M. Bigler, J. L. Touraine, R. Parkman, P. A. Tovo, J. Abrams, R. de Waal Malefyt, J. E. de Vries, M. G. Roncarolo, High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J. Exp. Med. 179, 493–502 (1994).
-
(1994)
J. Exp. Med.
, vol.179
, pp. 493-502
-
-
Bacchetta, R.1
Bigler, M.2
Touraine, J.L.3
Parkman, R.4
Tovo, P.A.5
Abrams, J.6
Malefyt, R.D.W.7
De Vries, J.E.8
Roncarolo, M.G.9
-
3
-
-
84874141619
-
The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells
-
S. Gregori, K. S. Goudy, M. G. Roncarolo, The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells. Front. Immunol. 3, 30 (2012).
-
(2012)
Front. Immunol.
, vol.3
, pp. 30
-
-
Gregori, S.1
Goudy, K.S.2
Roncarolo, M.G.3
-
4
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389, 737–742 (1997).
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O’Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
Roncarolo, M.G.7
-
5
-
-
81155160952
-
Type 1 regulatory T cells (Tr1) in autoimmunity
-
C. Pot, L. Apetoh, V. K. Kuchroo, Type 1 regulatory T cells (Tr1) in autoimmunity. Semin. Immunol. 23, 202–208 (2011).
-
(2011)
Semin. Immunol.
, vol.23
, pp. 202-208
-
-
Pot, C.1
Apetoh, L.2
Kuchroo, V.K.3
-
6
-
-
84906534462
-
Role of Blimp-1 in programing Th effector cells into IL-10 producers
-
C. Neumann, F. Heinrich, K. Neumann, V. Junghans, M.-F. Mashreghi, J. Ahlers, M. Janke, C. Rudolph, N. Mockel-Tenbrinck, A. A. Kühl, M. M. Heimesaat, C. Esser, S.-H. Im, A. Radbruch, S. Rutz, A. Scheffold, Role of Blimp-1 in programing Th effector cells into IL-10 producers. J. Exp. Med. 211, 1807–1819 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 1807-1819
-
-
Neumann, C.1
Heinrich, F.2
Neumann, K.3
Junghans, V.4
Mashreghi, M.-F.5
Ahlers, J.6
Janke, M.7
Rudolph, C.8
Mockel-Tenbrinck, N.9
Kühl, A.A.10
Heimesaat, M.M.11
Esser, C.12
Im, S.-H.13
Radbruch, A.14
Rutz, S.15
Scheffold, A.16
-
7
-
-
84956808926
-
Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated tissue pathology
-
M. Montes de Oca, R. Kumar, F. de Labastida Rivera, F. H. Amante, M. Sheel, R. J. Faleiro, P. T. Bunn, S. E. Best, L. Beattie, S. S. Ng, C. L. Edwards, W. Muller, E. Cretney, S. L. Nutt, M. J. Smyth, A. Haque, G. R. Hill, S. Sundar, A. Kallies, C. R. Engwerda, Blimp-1-dependent IL-10 production by Tr1 cells regulates TNF-mediated tissue pathology. PLOS Pathog. 12, e1005398 (2016).
-
(2016)
PLOS Pathog
, vol.12
-
-
Oca, M.M.D.1
Kumar, R.2
Rivera, F.D.L.3
Amante, F.H.4
Sheel, M.5
Faleiro, R.J.6
Bunn, P.T.7
Best, S.E.8
Beattie, L.9
Ng, S.S.10
Edwards, C.L.11
Muller, W.12
Cretney, E.13
Nutt, S.L.14
Smyth, M.J.15
Haque, A.16
Hill, G.R.17
Sundar, S.18
Kallies, A.19
Engwerda, C.R.20
more..
-
8
-
-
84900028407
-
+ T cells by inducing Blimp1
-
+ T cells by inducing Blimp1. Nat. Commun. 5, 3770 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3770
-
-
Heinemann, C.1
Heink, S.2
Petermann, F.3
Vasanthakumar, A.4
Rothhammer, V.5
Doorduijn, E.6
Mitsdoerffer, M.7
Sie, C.8
Costa, O.P.D.9
Buch, T.10
Hemmer, B.11
Oukka, M.12
Kallies, A.13
Korn, T.14
-
9
-
-
84880275285
-
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
-
N. Gagliani, C. F. Magnani, S. Huber, M. E. Gianolini, M. Pala, P. Licona-Limon, B. Guo, D. R. Herbert, A. Bulfone, F. Trentini, C. Di Serio, R. Bacchetta, M. Andreani, L. Brockmann, S. Gregori, R. A. Flavell, M.-G. Roncarolo, Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells. Nat. Med. 19, 739–746 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 739-746
-
-
Gagliani, N.1
Magnani, C.F.2
Huber, S.3
Gianolini, M.E.4
Pala, M.5
Licona-Limon, P.6
Guo, B.7
Herbert, D.R.8
Bulfone, A.9
Trentini, F.10
Di Serio, C.11
Bacchetta, R.12
Andreani, M.13
Brockmann, L.14
Gregori, S.15
Flavell, R.A.16
Roncarolo, M.-G.17
-
10
-
-
77955903212
-
The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
-
L. Apetoh, F. J. Quintana, C. Pot, N. Joller, S. Xiao, D. Kumar, E. J. Burns, D. H. Sherr, H. L. Weiner, V. K. Kuchroo, The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat. Immunol. 11, 854–861 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 854-861
-
-
Apetoh, L.1
Quintana, F.J.2
Pot, C.3
Joller, N.4
Xiao, S.5
Kumar, D.6
Burns, E.J.7
Sherr, D.H.8
Weiner, H.L.9
Kuchroo, V.K.10
-
12
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells
-
A. Awasthi, Y. Carrier, J. P. S. Peron, E. Bettelli, M. Kamanaka, R. A. Flavell, V. K. Kuchroo, M. Oukka, H. L. Weiner, A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells. Nat. Immunol. 8, 1380–1389 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.S.3
Bettelli, E.4
Kamanaka, M.5
Flavell, R.A.6
Kuchroo, V.K.7
Oukka, M.8
Weiner, H.L.9
-
13
-
-
79957713226
-
The Th1 life cycle: Molecular control of IFN- To IL-10 switching
-
A. Cope, G. Le Friec, J. Cardone, C. Kemper, The Th1 life cycle: Molecular control of IFN- to IL-10 switching. Trends Immunol. 32, 278–286 (2011).
-
(2011)
Trends Immunol
, vol.32
, pp. 278-286
-
-
Cope, A.1
Le Friec, G.2
Cardone, J.3
Kemper, C.4
-
14
-
-
65349171937
-
Graft-versus-host disease
-
J. L. M. Ferrara, J. E. Levine, P. Reddy, E. Holler, Graft-versus-host disease. Lancet 373, 1550–1561 (2009).
-
(2009)
Lancet
, vol.373
, pp. 1550-1561
-
-
Ferrara, J.L.M.1
Levine, J.E.2
Reddy, P.3
Holler, E.4
-
15
-
-
84861576998
-
Advances in graft-versus-host disease biology and therapy
-
B. R. Blazar, W. J. Murphy, M. Abedi, Advances in graft-versus-host disease biology and therapy. Nat. Rev. Immunol. 12, 443–458 (2012).
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 443-458
-
-
Blazar, B.R.1
Murphy, W.J.2
Abedi, M.3
-
16
-
-
77951870520
-
+ lymphopenia following allogeneic hematopoietic stem cell transplantation
-
+ lymphopenia following allogeneic hematopoietic stem cell transplantation. J. Clin. Invest. 120, 1479–1493 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1479-1493
-
-
Matsuoka, K.-I.1
Kim, H.T.2
McDonough, S.3
Bascug, G.4
Warshauer, B.5
Koreth, J.6
Cutler, C.7
Ho, V.T.8
Alyea, E.P.9
Antin, J.H.10
Soiffer, R.J.11
Ritz, J.12
-
17
-
-
0032533769
-
+ T cell-mediated graft-versus-host disease
-
+ T cell-mediated graft-versus-host disease. Transplantation 66, 1220–1229 (1998).
-
(1998)
Transplantation
, vol.66
, pp. 1220-1229
-
-
Blazar, B.R.1
Taylor, P.A.2
Panoskaltsis-Mortari, A.3
Narula, S.K.4
Smith, S.R.5
Roncarolo, M.G.6
Vallera, D.A.7
-
18
-
-
1942425058
-
Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance
-
E. S. Morris, K. P. A. MacDonald, V. Rowe, D. H. Johnson, T. Banovic, A. D. Clouston, G. R. Hill, Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance. Blood 103, 3573–3581 (2004).
-
(2004)
Blood
, vol.103
, pp. 3573-3581
-
-
Morris, E.S.1
MacDonald, K.P.A.2
Rowe, V.3
Johnson, D.H.4
Banovic, T.5
Clouston, A.D.6
Hill, G.R.7
-
19
-
-
33845453812
-
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse
-
M. Kamanaka, S. T. Kim, Y. Y. Wan, F. S. Sutterwala, M. Lara-Tejero, J. E. Galán, E. Harhaj, R. A. Flavell, Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity 25, 941–952 (2006).
-
(2006)
Immunity
, vol.25
, pp. 941-952
-
-
Kamanaka, M.1
Kim, S.T.2
Wan, Y.Y.3
Sutterwala, F.S.4
Lara-Tejero, M.5
Galán, J.E.6
Harhaj, E.7
Flavell, R.A.8
-
20
-
-
17044430217
-
Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
-
Y. Y. Wan, R. A. Flavell, Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl. Acad. Sci. U.S.A. 102, 5126–5131 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 5126-5131
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
21
-
-
79952955744
-
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
-
E. Cretney, A. Xin, W. Shi, M. Minnich, F. Masson, M. Miasari, G. T. Belz, G. K. Smyth, M. Busslinger, S. L. Nutt, A. Kallies, The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat. Immunol. 12, 304–311 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 304-311
-
-
Cretney, E.1
Xin, A.2
Shi, W.3
Minnich, M.4
Masson, F.5
Miasari, M.6
Belz, G.T.7
Smyth, G.K.8
Busslinger, M.9
Nutt, S.L.10
Kallies, A.11
-
22
-
-
68149100383
-
Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10–secreting Th1 cells
-
L. Gabryšová, K. S. Nicolson, H. B. Streeter, J. Verhagen, C. A. Sabatos-Peyton, D. J. Morgan, D. C. Wraith, Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10–secreting Th1 cells. J. Exp. Med. 206, 1755–1767 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1755-1767
-
-
Gabryšová, L.1
Nicolson, K.S.2
Streeter, H.B.3
Verhagen, J.4
Sabatos-Peyton, C.A.5
Morgan, D.J.6
Wraith, D.C.7
-
23
-
-
42649095378
-
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
-
F. J. Quintana, A. S. Basso, A. H. Iglesias, T. Korn, M. F. Farez, E. Bettelli, M. Caccamo, M. Oukka, H. L. Weiner, Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor. Nature 453, 65–71 (2008).
-
(2008)
Nature
, vol.453
, pp. 65-71
-
-
Quintana, F.J.1
Basso, A.S.2
Iglesias, A.H.3
Korn, T.4
Farez, M.F.5
Bettelli, E.6
Caccamo, M.7
Oukka, M.8
Weiner, H.L.9
-
24
-
-
84930576092
-
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-
-
I. D. Mascanfroni, M. C. Takenaka, A. Yeste, B. Patel, Y. Wu, J. E. Kenison, S. Siddiqui, A. S. Basso, L. E. Otterbein, D. M. Pardoll, F. Pan, A. Priel, C. B. Clish, S. C. Robson, F. J. Quintana, Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-. Nat. Med. 21, 638–646 (2015).
-
(2015)
Nat. Med.
, vol.21
, pp. 638-646
-
-
Mascanfroni, I.D.1
Takenaka, M.C.2
Yeste, A.3
Patel, B.4
Wu, Y.5
Kenison, J.E.6
Siddiqui, S.7
Basso, A.S.8
Otterbein, L.E.9
Pardoll, D.M.10
Pan, F.11
Priel, A.12
Clish, C.B.13
Robson, S.C.14
Quintana, F.J.15
-
25
-
-
84900448316
-
Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis
-
E. Zigmond, B. Bernshtein, G. Friedlander, C. R. Walker, S. Yona, K.-W. Kim, O. Brenner, R. Krauthgamer, C. Varol, W. Müller, S. Jung, Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis. Immunity 40, 720–733 (2014).
-
(2014)
Immunity
, vol.40
, pp. 720-733
-
-
Zigmond, E.1
Bernshtein, B.2
Friedlander, G.3
Walker, C.R.4
Yona, S.5
Kim, K.-W.6
Brenner, O.7
Krauthgamer, R.8
Varol, C.9
Müller, W.10
Jung, S.11
-
26
-
-
0030861750
-
Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines
-
G. R. Hill, J. M. Crawford, K. R. Cooke, Y. S. Brinson, L. Pan, J. L. M. Ferrara, Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines. Blood 90, 3204–3213 (1997).
-
(1997)
Blood
, vol.90
, pp. 3204-3213
-
-
Hill, G.R.1
Crawford, J.M.2
Cooke, K.R.3
Brinson, Y.S.4
Pan, L.5
Ferrara, J.L.M.6
-
27
-
-
84904498956
-
The biology of graft-versus-host disease: Experimental systems instructing clinical practice
-
K. A. Markey, K. P. A. MacDonald, G. R. Hill, The biology of graft-versus-host disease: Experimental systems instructing clinical practice. Blood 124, 354–362 (2014).
-
(2014)
Blood
, vol.124
, pp. 354-362
-
-
Markey, K.A.1
MacDonald, K.P.A.2
Hill, G.R.3
-
28
-
-
78449300568
-
A role for IL-27p28 as an antagonist of gp130-mediated signaling
-
J. S. Stumhofer, E. D. Tait, W. J. Quinn III, N. Hosken, B. Spudy, R. Goenka, C. A. Fielding, A. C. O’Hara, Y. Chen, M. L. Jones, C. J. M. Saris, S. Rose-John, D. J. Cua, S. A. Jones, M. Merle Elloso, J. Grötzinger, M. P. Cancro, S. D. Levin, C. A. Hunter, A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat. Immunol. 11, 1119–1126 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 1119-1126
-
-
Stumhofer, J.S.1
Tait, E.D.2
Quinn, W.J.3
Hosken, N.4
Spudy, B.5
Goenka, R.6
Fielding, C.A.7
O’Hara, A.C.8
Chen, Y.9
Jones, M.L.10
Saris, C.J.M.11
Rose-John, S.12
Cua, D.J.13
Jones, S.A.14
Elloso, M.M.15
Grötzinger, J.16
Cancro, M.P.17
Levin, S.D.18
Hunter, C.A.19
-
29
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
J. M. Kim, J. P. Rasmussen, A. Y. Rudensky, Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8, 191–197 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
31
-
-
33846423147
-
+ regulatory T cells induces a scurfy-like disease
-
+ regulatory T cells induces a scurfy-like disease. J. Exp. Med. 204, 57–63 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
Hamann, A.7
Wagner, H.8
Huehn, J.9
Sparwasser, T.10
-
33
-
-
34249678457
-
TH1 cells control themselves by producing interleukin-10
-
A. O’Garra, P. Vieira, TH1 cells control themselves by producing interleukin-10. Nat. Rev. Immunol. 7, 425–428 (2007).
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 425-428
-
-
O’Garra, A.1
Vieira, P.2
-
34
-
-
84862777436
-
The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation
-
S. M. Gordon, J. Chaix, L. J. Rupp, J. Wu, S. Madera, J. C. Sun, T. Lindsten, S. L. Reiner, The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation. Immunity 36, 55–67 (2012).
-
(2012)
Immunity
, vol.36
, pp. 55-67
-
-
Gordon, S.M.1
Chaix, J.2
Rupp, L.J.3
Wu, J.4
Madera, S.5
Sun, J.C.6
Lindsten, T.7
Reiner, S.L.8
-
35
-
-
30044440799
-
+ T cell fate coupled by T-bet and eomesodermin
-
+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 6, 1236–1244 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1236-1244
-
-
Intlekofer, A.M.1
Takemoto, N.2
Wherry, E.J.3
Longworth, S.A.4
Northrup, J.T.5
Palanivel, V.R.6
Mullen, A.C.7
Gasink, C.R.8
Kaech, S.M.9
Miller, J.D.10
Gapin, L.11
Ryan, K.12
Russ, A.P.13
Lindsten, T.14
Orange, J.S.15
Goldrath, A.W.16
Ahmed, R.17
Reiner, S.L.18
-
36
-
-
84943339273
-
Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation
-
B. J. E. Raveney, S. Oki, H. Hohjoh, M. Nakamura, W. Sato, M. Murata, T. Yamamura, Eomesodermin-expressing T-helper cells are essential for chronic neuroinflammation. Nat. Commun. 6, 8437 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 8437
-
-
Raveney, B.J.E.1
Oki, S.2
Hohjoh, H.3
Nakamura, M.4
Sato, W.5
Murata, M.6
Yamamura, T.7
-
37
-
-
84878648242
-
Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin
-
M. A. Curran, T. L. Geiger, W. Montalvo, M. Kim, S. L. Reiner, A. Al-Shamkhani, J. C. Sun, J. P. Allison, Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin. J. Exp. Med. 210, 743–755 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 743-755
-
-
Curran, M.A.1
Geiger, T.L.2
Montalvo, W.3
Kim, M.4
Reiner, S.L.5
Al-Shamkhani, A.6
Sun, J.C.7
Allison, J.P.8
-
38
-
-
84958659945
-
+ T cells restricts peripheral Foxp3 induction
-
+ T cells restricts peripheral Foxp3 induction. J. Immunol. 195, 4742–4752 (2015).
-
(2015)
J. Immunol.
, vol.195
, pp. 4742-4752
-
-
Lupar, E.1
Brack, M.2
Garnier, L.3
Laffont, S.4
Rauch, K.S.5
Schachtrup, K.6
Arnold, S.J.7
Guéry, J.-C.8
Izcue, A.9
-
39
-
-
79956324792
-
Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor- Is mediated by suppression of eomesodermin
-
K. Ichiyama, T. Sekiya, N. Inoue, T. Tamiya, I. Kashiwagi, A. Kimura, R. Morita, G. Muto, T. Shichita, R. Takahashi, A. Yoshimura, Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor- is mediated by suppression of eomesodermin. Immunity 34, 741–754 (2011).
-
(2011)
Immunity
, vol.34
, pp. 741-754
-
-
Ichiyama, K.1
Sekiya, T.2
Inoue, N.3
Tamiya, T.4
Kashiwagi, I.5
Kimura, A.6
Morita, R.7
Muto, G.8
Shichita, T.9
Takahashi, R.10
Yoshimura, A.11
-
40
-
-
84929955331
-
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
-
N. Gagliani, M. Carolina Amezcua Vesely, A. Iseppon, L. Brockmann, H. Xu, N. W. Palm, M. R. de Zoete, P. Licona-Limón, R. S. Paiva, T. Ching, C. Weaver, X. Zi, X. Pan, R. Fan, L. X. Garmire, M. J. Cotton, Y. Drier, B. Bernstein, J. Geginat, B. Stockinger, E. Esplugues, S. Huber, R. A. Flavell, Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation. Nature 523, 221–225 (2015).
-
(2015)
Nature
, vol.523
, pp. 221-225
-
-
Gagliani, N.1
Vesely, M.C.A.2
Iseppon, A.3
Brockmann, L.4
Xu, H.5
Palm, N.W.6
De Zoete, M.R.7
Licona-Limón, P.8
Paiva, R.S.9
Ching, T.10
Weaver, C.11
Zi, X.12
Pan, X.13
Fan, R.14
Garmire, L.X.15
Cotton, M.J.16
Drier, Y.17
Bernstein, B.18
Geginat, J.19
Stockinger, B.20
Esplugues, E.21
Huber, S.22
Flavell, R.A.23
more..
-
41
-
-
77955890952
-
Interleukin-23 drives intestinal inflammation through direct activity on T cells
-
P. P. Ahern, C. Schiering, S. Buonocore, M. J. McGeachy, D. J. Cua, K. J. Maloy, F. Powrie, Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity 33, 279–288 (2010).
-
(2010)
Immunity
, vol.33
, pp. 279-288
-
-
Ahern, P.P.1
Schiering, C.2
Buonocore, S.3
McGeachy, M.J.4
Cua, D.J.5
Maloy, K.J.6
Powrie, F.7
-
42
-
-
36248965294
-
TGF- And IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology
-
M. J. McGeachy, K. S. Bak-Jensen, Y. Chen, C. M. Tato, W. Blumenschein, T. McClanahan, D. J. Cua, TGF- and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell–mediated pathology. Nat. Immunol. 8, 1390–1397 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-Jensen, K.S.2
Chen, Y.3
Tato, C.M.4
Blumenschein, W.5
McClanahan, T.6
Cua, D.J.7
-
44
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells
-
M. Batten, J. Li, S. Yi, N. M. Kljavin, D. M. Danilenko, S. Lucas, J. Lee, F. J. de Sauvage, N. Ghilardi, Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17–producing T cells. Nat. Immunol. 7, 929–936 (2006).
-
(2006)
Nat. Immunol.
, vol.7
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
Kljavin, N.M.4
Danilenko, D.M.5
Lucas, S.6
Lee, J.7
De Sauvage, F.J.8
Ghilardi, N.9
-
45
-
-
84992051377
-
Blockade of interleukin–27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing FOXP3 expression
-
L. Belle, K. Agle, V. Zhou, C. Yin-Yuan, R. Komorowski, D. Eastwood, B. Logan, J. Sun, N. Ghilardi, D. Cua, C. B. Williams, M. Gaignage, R. Marillier, J. van Snick, W. R. Drobyski, Blockade of interleukin–27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing FOXP3 expression. Blood 128, 2068–2082 (2016).
-
(2016)
Blood
, vol.128
, pp. 2068-2082
-
-
Belle, L.1
Agle, K.2
Zhou, V.3
Yin-Yuan, C.4
Komorowski, R.5
Eastwood, D.6
Logan, B.7
Sun, J.8
Ghilardi, N.9
Cua, D.10
Williams, C.B.11
Gaignage, M.12
Marillier, R.13
Van Snick, J.14
Drobyski, W.R.15
-
46
-
-
84925228691
-
Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: A phase 1/2 trial
-
G. A. Kennedy, A. Varelias, S. Vuckovic, L. Le Texier, K. H. Gartlan, P. Zhang, G. Thomas, L. Anderson, G. Boyle, N. Cloonan, J. Leach, E. Sturgeon, J. Avery, S. D. Olver, M. Lor, A. K. Misra, C. Hutchins, A. J. Morton, S. T. Durrant, E. Subramoniapillai, J. P. Butler, C. I. Curley, K. P. MacDonald, S. K. Tey, G. R. Hill, Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: A phase 1/2 trial. Lancet Oncol. 15, 1451–1459 (2014).
-
(2014)
Lancet Oncol
, vol.15
, pp. 1451-1459
-
-
Kennedy, G.A.1
Varelias, A.2
Vuckovic, S.3
Le Texier, L.4
Gartlan, K.H.5
Zhang, P.6
Thomas, G.7
Anderson, L.8
Boyle, G.9
Cloonan, N.10
Leach, J.11
Sturgeon, E.12
Avery, J.13
Olver, S.D.14
Lor, M.15
Misra, A.K.16
Hutchins, C.17
Morton, A.J.18
Durrant, S.T.19
Subramoniapillai, E.20
Butler, J.P.21
Curley, C.I.22
MacDonald, K.P.23
Tey, S.K.24
Hill, G.R.25
more..
-
47
-
-
84886790466
-
T-bet: A bridge between innate and adaptive immunity
-
V. Lazarevic, L. H. Glimcher, G. M. Lord, T-bet: A bridge between innate and adaptive immunity. Nat. Rev. Immunol. 13, 777–789 (2013).
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 777-789
-
-
Lazarevic, V.1
Glimcher, L.H.2
Lord, G.M.3
-
48
-
-
60549090859
-
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs
-
F. Cruz-Guilloty, M. E. Pipkin, I. M. Djuretic, D. Levanon, J. Lotem, M. G. Lichtenheld, Y. Groner, A. Rao, Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J. Exp. Med. 206, 51–59 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 51-59
-
-
Cruz-Guilloty, F.1
Pipkin, M.E.2
Djuretic, I.M.3
Levanon, D.4
Lotem, J.5
Lichtenheld, M.G.6
Groner, Y.7
Rao, A.8
-
49
-
-
84876436991
-
+ T cells
-
+ T cells. Eur. J. Immunol. 43, 1063–1073 (2013).
-
(2013)
Eur. J. Immunol.
, vol.43
, pp. 1063-1073
-
-
Iwasaki, Y.1
Fujio, K.2
Okamura, T.3
Yanai, A.4
Sumitomo, S.5
Shoda, H.6
Tamura, T.7
Yoshida, H.8
Charnay, P.9
Yamamoto, K.10
-
50
-
-
84960194165
-
+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet
-
+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nat. Immunol. 17, 422–432 (2016).
-
(2016)
Nat. Immunol.
, vol.17
, pp. 422-432
-
-
Xin, A.1
Masson, F.2
Liao, Y.3
Preston, S.4
Guan, T.5
Gloury, R.6
Olshansky, M.7
Lin, J.-X.8
Li, P.9
Speed, T.P.10
Smyth, G.K.11
Ernst, M.12
Leonard, W.J.13
Pellegrini, M.14
Kaech, S.M.15
Nutt, S.L.16
Shi, W.17
Belz, G.T.18
Kallies, A.19
-
52
-
-
7244231012
-
Plasma cell ontogeny defined by quantitative changes in blimp-1 expression
-
A. Kallies, J. Hasbold, D. M. Tarlinton, W. Dietrich, L. M. Corcoran, P. D. Hodgkin, S. L. Nutt, Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J. Exp. Med. 200, 967–977 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 967-977
-
-
Kallies, A.1
Hasbold, J.2
Tarlinton, D.M.3
Dietrich, W.4
Corcoran, L.M.5
Hodgkin, P.D.6
Nutt, S.L.7
-
53
-
-
75149114226
-
Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model
-
M. C. Pils, F. Pisano, N. Fasnacht, J.-M. Heinrich, L. Groebe, A. Schippers, B. Rozell, R. S. Jack, W. Müller, Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model. Eur. J. Immunol. 40, 443–448 (2010).
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 443-448
-
-
Pils, M.C.1
Pisano, F.2
Fasnacht, N.3
Heinrich, J.-M.4
Groebe, L.5
Schippers, A.6
Rozell, B.7
Jack, R.S.8
Müller, W.9
-
54
-
-
9244237038
-
T cell–specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation
-
A. Roers, L. Siewe, E. Strittmatter, M. Deckert, D. Schlüter, W. Stenzel, A. D. Gruber, T. Krieg, K. Rajewsky, W. Müller, T cell–specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J. Exp. Med. 200, 1289–1297 (2004).
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1289-1297
-
-
Roers, A.1
Siewe, L.2
Strittmatter, E.3
Deckert, M.4
Schlüter, D.5
Stenzel, W.6
Gruber, A.D.7
Krieg, T.8
Rajewsky, K.9
Müller, W.10
-
55
-
-
84946149406
-
CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells
-
E. E. Kara, D. R. McKenzie, C. R. Bastow, C. E. Gregor, K. A. Fenix, A. D. Ogunniyi, J. C. Paton, M. Mack, D. R. Pombal, C. Seillet, B. Dubois, A. Liston, K. P. A. MacDonald, G. T. Belz, M. J. Smyth, G. R. Hill, I. Comerford, S. R. McColl, CCR2 defines in vivo development and homing of IL-23-driven GM-CSF-producing Th17 cells. Nat. Commun. 6, 8644 (2015).
-
(2015)
Nat. Commun.
, vol.6
, pp. 8644
-
-
Kara, E.E.1
McKenzie, D.R.2
Bastow, C.R.3
Gregor, C.E.4
Fenix, K.A.5
Ogunniyi, A.D.6
Paton, J.C.7
Mack, M.8
Pombal, D.R.9
Seillet, C.10
Dubois, B.11
Liston, A.12
MacDonald, K.P.A.13
Belz, G.T.14
Smyth, M.J.15
Hill, G.R.16
Comerford, I.17
McColl, S.R.18
-
56
-
-
84887416283
-
Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo
-
P. Zhang, S.-K. Tey, M. Koyama, R. D. Kuns, S. D. Olver, K. E. Lineburg, M. Lor, B. E. Teal, N. C. Raffelt, J. Raju, L. Leveque, K. A. Markey, A. Varelias, A. D. Clouston, S. W. Lane, K. P. A. MacDonald, G. R. Hill, Induced regulatory T cells promote tolerance when stabilized by rapamycin and IL-2 in vivo. J. Immunol. 191, 5291–5303 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 5291-5303
-
-
Zhang, P.1
Tey, S.-K.2
Koyama, M.3
Kuns, R.D.4
Olver, S.D.5
Lineburg, K.E.6
Lor, M.7
Teal, B.E.8
Raffelt, N.C.9
Raju, J.10
Leveque, L.11
Markey, K.A.12
Varelias, A.13
Clouston, A.D.14
Lane, S.W.15
MacDonald, K.P.A.16
Hill, G.R.17
-
57
-
-
34547933330
-
IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract
-
A. C. Burman, T. Banovic, R. D. Kuns, A. D. Clouston, A. C. Stanley, E. S. Morris, V. Rowe, H. Bofinger, R. Skoczylas, N. Raffelt, O. Fahy, S. R. McColl, C. R. Engwerda, K. P. A. McDonald, G. R. Hill, IFN differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract. Blood 110, 1064–1072 (2007).
-
(2007)
Blood
, vol.110
, pp. 1064-1072
-
-
Burman, A.C.1
Banovic, T.2
Kuns, R.D.3
Clouston, A.D.4
Stanley, A.C.5
Morris, E.S.6
Rowe, V.7
Bofinger, H.8
Skoczylas, R.9
Raffelt, N.10
Fahy, O.11
McColl, S.R.12
Engwerda, C.R.13
McDonald, K.P.A.14
Hill, G.R.15
-
58
-
-
84964697658
-
+ dendritic cells determine the severity of acute graft-versus-host disease
-
+ dendritic cells determine the severity of acute graft-versus-host disease. J. Exp. Med. 212, 1303–1321 (2015).
-
(2015)
J. Exp. Med.
, vol.212
, pp. 1303-1321
-
-
Koyama, M.1
Cheong, M.2
Markey, K.A.3
Gartlan, K.H.4
Kuns, R.D.5
Locke, K.R.6
Lineburg, K.E.7
Teal, B.E.8
Mouttie, L.L.-E.9
Bunting, M.D.10
Vuckovic, S.11
Zhang, P.12
Teng, M.W.L.13
Varelias, A.14
Tey, S.-K.15
Wockner, L.F.16
Engwerda, C.R.17
Smyth, M.J.18
Belz, G.T.19
McColl, S.R.20
MacDonald, K.P.A.21
Hill, G.R.22
more..
|