-
1
-
-
34247523141
-
Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation
-
Kastelein, R. A., Hunter, C. A. and Cua, D. J., Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Annu. Rev. Immunol. 2007. 25: 221-242.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 221-242
-
-
Kastelein, R.A.1
Hunter, C.A.2
Cua, D.J.3
-
2
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G., Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 2003. 3: 133-146.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
3
-
-
18444385868
-
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
-
Pflanz, S., Timans, J. C., Cheung, J., Rosales, R., Kanzler, H., Gilbert, J., Hibbert, L. et al., IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002. 16: 779-790.
-
(2002)
Immunity
, vol.16
, pp. 779-790
-
-
Pflanz, S.1
Timans, J.C.2
Cheung, J.3
Rosales, R.4
Kanzler, H.5
Gilbert, J.6
Hibbert, L.7
-
4
-
-
10744222574
-
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
-
Pflanz, S., Hibbert, L., Mattson, J., Rosales, R., Vaisberg, E., Bazan, J. F., Phillips, J. H. et al., WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J. Immunol. 2004. 172: 2225-2231.
-
(2004)
J. Immunol.
, vol.172
, pp. 2225-2231
-
-
Pflanz, S.1
Hibbert, L.2
Mattson, J.3
Rosales, R.4
Vaisberg, E.5
Bazan, J.F.6
Phillips, J.H.7
-
5
-
-
0345570521
-
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
-
Villarino, A., Hibbert, L., Lieberman, L., Wilson, E., Mak, T., Yoshida, H., Kastelein, R. A. et al., The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 2003. 19: 645-655.
-
(2003)
Immunity
, vol.19
, pp. 645-655
-
-
Villarino, A.1
Hibbert, L.2
Lieberman, L.3
Wilson, E.4
Mak, T.5
Yoshida, H.6
Kastelein, R.A.7
-
6
-
-
84870873399
-
Interleukin-27: balancing protective and pathological immunity
-
Hunter, C. A. and Kastelein, R., Interleukin-27: balancing protective and pathological immunity. Immunity 2012. 37: 960-969.
-
(2012)
Immunity
, vol.37
, pp. 960-969
-
-
Hunter, C.A.1
Kastelein, R.2
-
7
-
-
0038326688
-
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
-
Takeda, A., Hamano, S., Yamanaka, A., Hanada, T., Ishibashi, T., Mak, T. W., Yoshimura, A. et al., Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J. Immunol. 2003. 170: 4886-4890.
-
(2003)
J. Immunol.
, vol.170
, pp. 4886-4890
-
-
Takeda, A.1
Hamano, S.2
Yamanaka, A.3
Hanada, T.4
Ishibashi, T.5
Mak, T.W.6
Yoshimura, A.7
-
8
-
-
23444462668
-
A role for IL-27 in early regulation of Th1 differentiation
-
Owaki, T., Asakawa, M., Morishima, N., Hata, K., Fukai, F., Matsui, M., Mizuguchi, J. et al., A role for IL-27 in early regulation of Th1 differentiation. J. Immunol. 2005. 175: 2191-2200.
-
(2005)
J. Immunol.
, vol.175
, pp. 2191-2200
-
-
Owaki, T.1
Asakawa, M.2
Morishima, N.3
Hata, K.4
Fukai, F.5
Matsui, M.6
Mizuguchi, J.7
-
9
-
-
10744221849
-
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production
-
Hamano, S., Himeno, K., Miyazaki, Y., Ishii, K., Yamanaka, A., Takeda, A., Zhang, M. et al., WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. Immunity 2003. 19: 657-667.
-
(2003)
Immunity
, vol.19
, pp. 657-667
-
-
Hamano, S.1
Himeno, K.2
Miyazaki, Y.3
Ishii, K.4
Yamanaka, A.5
Takeda, A.6
Zhang, M.7
-
10
-
-
29644443883
-
IL-27 limits IL-2 production during Th1 differentiation
-
Villarino, A. V., Stumhofer, J. S., Saris, C. J., Kastelein, R. A., de Sauvage, F. J. and Hunter, C. A., IL-27 limits IL-2 production during Th1 differentiation. J. Immunol. 2006. 176: 237-247.
-
(2006)
J. Immunol.
, vol.176
, pp. 237-247
-
-
Villarino, A.V.1
Stumhofer, J.S.2
Saris, C.J.3
Kastelein, R.A.4
de Sauvage, F.J.5
Hunter, C.A.6
-
11
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
-
Batten, M., Li, J., Yi, S., Kljavin, N. M., Danilenko, D. M., Lucas, S., Lee, J. et al., Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat. Immunol. 2006. 7: 929-936.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
Kljavin, N.M.4
Danilenko, D.M.5
Lucas, S.6
Lee, J.7
-
12
-
-
66949157620
-
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells
-
Diveu, C., McGeachy, M. J., Boniface, K., Stumhofer, J. S., Sathe, M., Joyce-Shaikh, B., Chen, Y. et al., IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. J. Immunol. 2009. 182: 5748-5756.
-
(2009)
J. Immunol.
, vol.182
, pp. 5748-5756
-
-
Diveu, C.1
McGeachy, M.J.2
Boniface, K.3
Stumhofer, J.S.4
Sathe, M.5
Joyce-Shaikh, B.6
Chen, Y.7
-
13
-
-
38149045608
-
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation
-
Yoshimoto, T., Yoshimoto, T., Yasuda, K., Mizuguchi, J. and Nakanishi, K., IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. J. Immunol. 2007. 179: 4415-4423.
-
(2007)
J. Immunol.
, vol.179
, pp. 4415-4423
-
-
Yoshimoto, T.1
Yoshimoto, T.2
Yasuda, K.3
Mizuguchi, J.4
Nakanishi, K.5
-
14
-
-
36248970701
-
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
-
Awasthi, A., Carrier, Y., Peron, J. P., Bettelli, E., Kamanaka, M., Flavell, R. A., Kuchroo, V. K. et al., A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat. Immunol. 2007. 8: 1380-1389.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1380-1389
-
-
Awasthi, A.1
Carrier, Y.2
Peron, J.P.3
Bettelli, E.4
Kamanaka, M.5
Flavell, R.A.6
Kuchroo, V.K.7
-
15
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer, J. S., Silver, J. S., Laurence, A., Porrett, P. M., Harris, T. H., Turka, L. A., Ernst, M. et al., Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat. Immunol. 2007. 8: 1363-1371.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
Ernst, M.7
-
16
-
-
36248970702
-
Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald, D. C., Zhang, G. X., El-Behi, M., Fonseca-Kelly, Z., Li, H., Yu, S., Saris, C. J. et al., Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol. 2007. 8: 1372-1379.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
El-Behi, M.3
Fonseca-Kelly, Z.4
Li, H.5
Yu, S.6
Saris, C.J.7
-
17
-
-
69249083836
-
Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
-
Pot, C., Jin, H., Awasthi, A., Liu, S. M., Lai, C. Y., Madan, R., Sharpe, A. H. et al., Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J. Immunol. 2009. 183: 797-801.
-
(2009)
J. Immunol.
, vol.183
, pp. 797-801
-
-
Pot, C.1
Jin, H.2
Awasthi, A.3
Liu, S.M.4
Lai, C.Y.5
Madan, R.6
Sharpe, A.H.7
-
18
-
-
73249149628
-
c-Maf regulates IL-10 expression during Th17 polarization
-
Xu, J., Yang, Y., Qiu, G., Lal, G., Wu, Z., Levy, D. E., Ochando, J. C. et al., c-Maf regulates IL-10 expression during Th17 polarization. J. Immunol. 2009. 182: 6226-6236.
-
(2009)
J. Immunol.
, vol.182
, pp. 6226-6236
-
-
Xu, J.1
Yang, Y.2
Qiu, G.3
Lal, G.4
Wu, Z.5
Levy, D.E.6
Ochando, J.C.7
-
19
-
-
77955903212
-
The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
-
Apetoh, L., Quintana, F. J., Pot, C., Joller, N., Xiao, S., Kumar, D., Burns, E. J. et al., The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat. Immunol. 2010. 11: 854-861.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 854-861
-
-
Apetoh, L.1
Quintana, F.J.2
Pot, C.3
Joller, N.4
Xiao, S.5
Kumar, D.6
Burns, E.J.7
-
20
-
-
84862135028
-
Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells
-
Carrier, Y., Whitters, M. J., Miyashiro, J. S., LaBranche, T. P., Ramon, H. E., Benoit, S. E., Ryan, M. S. et al., Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells. Eur. J. Immunol. 2012. 42: 1393-1404.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1393-1404
-
-
Carrier, Y.1
Whitters, M.J.2
Miyashiro, J.S.3
LaBranche, T.P.4
Ramon, H.E.5
Benoit, S.E.6
Ryan, M.S.7
-
21
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva, M. and O'Garra, A., The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 2010. 10: 170-181.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
22
-
-
79956085898
-
NFIL3/E4BP4 controls type 2 T helper cell cytokine expression
-
Kashiwada, M., Cassel, S. L., Colgan, J. D. and Rothman, P. B., NFIL3/E4BP4 controls type 2 T helper cell cytokine expression. EMBO. J. 2011. 30: 2071-2082.
-
(2011)
EMBO. J.
, vol.30
, pp. 2071-2082
-
-
Kashiwada, M.1
Cassel, S.L.2
Colgan, J.D.3
Rothman, P.B.4
-
23
-
-
68149125188
-
IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines
-
Ahyi, A. N., Chang, H. C., Dent, A. L., Nutt, S. L. and Kaplan, M. H., IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines. J. Immunol. 2009. 183: 1598-1606.
-
(2009)
J. Immunol.
, vol.183
, pp. 1598-1606
-
-
Ahyi, A.N.1
Chang, H.C.2
Dent, A.L.3
Nutt, S.L.4
Kaplan, M.H.5
-
24
-
-
79952955744
-
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
-
Cretney, E., Xin, A., Shi, W., Minnich, M., Masson, F., Miasari, M., Belz, G. T. et al., The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat. Immunol. 2011. 12: 304-311.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 304-311
-
-
Cretney, E.1
Xin, A.2
Shi, W.3
Minnich, M.4
Masson, F.5
Miasari, M.6
Belz, G.T.7
-
26
-
-
69549124480
-
CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2
-
Okamura, T., Fujio, K., Shibuya, M., Sumitomo, S., Shoda, H., Sakaguchi, S. and Yamamoto, K., CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2. Proc. Natl. Acad. Sci. USA 2009. 106: 13974-13979.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13974-13979
-
-
Okamura, T.1
Fujio, K.2
Shibuya, M.3
Sumitomo, S.4
Shoda, H.5
Sakaguchi, S.6
Yamamoto, K.7
-
27
-
-
64849083153
-
IL-21 mediates suppressive effects via its induction of IL-10
-
Spolski, R., Kim, H.-P., Zhu, W., Levy, D. E. and Leonard, W. J., IL-21 mediates suppressive effects via its induction of IL-10. J. Immunol. 2009. 182: 2859-2867.
-
(2009)
J. Immunol.
, vol.182
, pp. 2859-2867
-
-
Spolski, R.1
Kim, H.-P.2
Zhu, W.3
Levy, D.E.4
Leonard, W.J.5
-
28
-
-
0033152267
-
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
-
Kim, J. I., Ho, I. C., Grusby, M. J. and Glimcher, L. H., The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity 1999. 10: 745-751.
-
(1999)
Immunity
, vol.10
, pp. 745-751
-
-
Kim, J.I.1
Ho, I.C.2
Grusby, M.J.3
Glimcher, L.H.4
-
29
-
-
84867861268
-
BATF-JUN is critical for IRF4-mediated transcription in T cells
-
Li, P., Spolski, R., Liao, W., Wang, L., Murphy, T. L., Murphy, K. M. and Leonard, W. J., BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 2012. 490: 543-546.
-
(2012)
Nature
, vol.490
, pp. 543-546
-
-
Li, P.1
Spolski, R.2
Liao, W.3
Wang, L.4
Murphy, T.L.5
Murphy, K.M.6
Leonard, W.J.7
-
30
-
-
79952994082
-
CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs
-
Sun, J., Dodd, H., Moser, E. K., Sharma, R. and Braciale, T. J., CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs. Nat. Immunol. 2011. 12: 327-334.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 327-334
-
-
Sun, J.1
Dodd, H.2
Moser, E.K.3
Sharma, R.4
Braciale, T.J.5
-
31
-
-
33645979374
-
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance
-
Kallies, A., Hawkins, E. D., Belz, G. T., Metcalf, D., Hommel, M., Corcoran, L. M., Hodgkin, P. D. et al., Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nat. Immunol. 2006. 7: 466-474.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 466-474
-
-
Kallies, A.1
Hawkins, E.D.2
Belz, G.T.3
Metcalf, D.4
Hommel, M.5
Corcoran, L.M.6
Hodgkin, P.D.7
-
32
-
-
84871168621
-
B lymphocyte-induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17-producing CD4+ T cells
-
Salehi, S., Bankoti, R., Benevides, L., Willen, J., Couse, M., Silva, J. S., Dhall, D. et al., B lymphocyte-induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17-producing CD4+ T cells. J. Immunol. 2012. 189: 5682-5693.
-
(2012)
J. Immunol.
, vol.189
, pp. 5682-5693
-
-
Salehi, S.1
Bankoti, R.2
Benevides, L.3
Willen, J.4
Couse, M.5
Silva, J.S.6
Dhall, D.7
-
33
-
-
0030704726
-
A CD4 +T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux, H., O'Garra, A., Bigler, M., Rouleau, M., Antonenko, S., de Vries, J. E. and Roncarolo, M. G., A CD4 +T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997. 389: 737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
de Vries, J.E.6
Roncarolo, M.G.7
-
34
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
Hirota, K., Duarte, J. H., Veldhoen, M., Hornsby, E., Li, Y., Cua, D. J., Ahlfors, H. et al., Fate mapping of IL-17-producing T cells in inflammatory responses. Nat. Immunol. 2011. 12: 255-263.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 255-263
-
-
Hirota, K.1
Duarte, J.H.2
Veldhoen, M.3
Hornsby, E.4
Li, Y.5
Cua, D.J.6
Ahlfors, H.7
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