메뉴 건너뛰기




Volumn 49, Issue 9, 2017, Pages 1346-1353

Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS DNA; CYCLINE; DNA; PROTEIN KINASE; TNNI3K PROTEIN, MOUSE;

EID: 85028707436     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3929     Document Type: Article
Times cited : (239)

References (52)
  • 1
    • 33750734736 scopus 로고    scopus 로고
    • Cardiomyocyte DNA synthesis and binucleation during murine development
    • Soonpaa, M.H., Kim, K.K., Pajak, L., Franklin, M. & Field, L.J. Cardiomyocyte DNA synthesis and binucleation during murine development. Am. J. Physiol. 271, H2183-H2189 (1996).
    • (1996) Am. J. Physiol. , vol.271 , pp. H2183-H2189
    • Soonpaa, M.H.1    Kim, K.K.2    Pajak, L.3    Franklin, M.4    Field, L.J.5
  • 2
    • 79952065525 scopus 로고    scopus 로고
    • Transient regenerative potential of the neonatal mouse heart
    • Porrello, E.R. et al. Transient regenerative potential of the neonatal mouse heart. Science 331, 1078-1080 (2011).
    • (2011) Science , vol.331 , pp. 1078-1080
    • Porrello, E.R.1
  • 3
    • 0037073890 scopus 로고    scopus 로고
    • Heart regeneration in zebrafish
    • Poss, K.D., Wilson, L.G. & Keating, M.T. Heart regeneration in zebrafish. Science 298, 2188-2190 (2002).
    • (2002) Science , vol.298 , pp. 2188-2190
    • Poss, K.D.1    Wilson, L.G.2    Keating, M.T.3
  • 4
    • 0015993323 scopus 로고
    • Response of the adult newt ventricle to injury
    • Oberpriller, J.O. & Oberpriller, J.C. Response of the adult newt ventricle to injury. J. Exp. Zool. 187, 249-253 (1974).
    • (1974) J. Exp. Zool. , vol.187 , pp. 249-253
    • Oberpriller, J.O.1    Oberpriller, J.C.2
  • 5
    • 77950200829 scopus 로고    scopus 로고
    • Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
    • Jopling, C. et al. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464, 606-609 (2010).
    • (2010) Nature , vol.464 , pp. 606-609
    • Jopling, C.1
  • 6
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann, O. et al. Evidence for cardiomyocyte renewal in humans. Science 324, 98-102 (2009).
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1
  • 7
    • 84872611623 scopus 로고    scopus 로고
    • Mammalian heart renewal by pre-existing cardiomyocytes
    • Senyo, S.E. et al. Mammalian heart renewal by pre-existing cardiomyocytes. Nature 493, 433-436 (2013).
    • (2013) Nature , vol.493 , pp. 433-436
    • Senyo, S.E.1
  • 8
    • 84902602979 scopus 로고    scopus 로고
    • Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice
    • Ali, S.R. et al. Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. Proc. Natl. Acad. Sci. USA 111, 8850-8855 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 8850-8855
    • Ali, S.R.1
  • 9
    • 0030219688 scopus 로고    scopus 로고
    • Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development
    • Li, F., Wang, X., Capasso, J.M. & Gerdes, A.M. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development. J. Mol. Cell. Cardiol. 28, 1737-1746 (1996).
    • (1996) J. Mol. Cell. Cardiol. , vol.28 , pp. 1737-1746
    • Li, F.1    Wang, X.2    Capasso, J.M.3    Gerdes, A.M.4
  • 10
    • 0029365061 scopus 로고
    • Cardiomyocyte proliferation and hypertrophy in the human fetus: Quantitative study of the myocyte nuclei
    • Xavier-Vidal, R. & Mandarim-de-Lacerda, C.A. Cardiomyocyte proliferation and hypertrophy in the human fetus: quantitative study of the myocyte nuclei. Bull. Assoc. Anat. (Nancy) 79, 27-31 (1995).
    • (1995) Bull. Assoc. Anat. (Nancy) , vol.79 , pp. 27-31
    • Xavier-Vidal, R.1    Mandarim-De-Lacerda, C.A.2
  • 11
    • 77950201708 scopus 로고    scopus 로고
    • Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes
    • Kikuchi, K. et al. Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes. Nature 464, 601-605 (2010).
    • (2010) Nature , vol.464 , pp. 601-605
    • Kikuchi, K.1
  • 12
    • 84872876842 scopus 로고    scopus 로고
    • Cardiomyocyte proliferation contributes to heart growth in young humans
    • Mollova, M. et al. Cardiomyocyte proliferation contributes to heart growth in young humans. Proc. Natl. Acad. Sci. USA 110, 1446-1451 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 1446-1451
    • Mollova, M.1
  • 13
    • 84961171836 scopus 로고    scopus 로고
    • Cardiomyocytes in young infants with congenital heart disease: A three-month window of proliferation
    • Ye, L. et al. Cardiomyocytes in young infants with congenital heart disease: a three-month window of proliferation. Sci. Rep. 6, 23188 (2016).
    • (2016) Sci. Rep. , vol.6 , pp. 23188
    • Ye, L.1
  • 14
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • Bersell, K., Arab, S., Haring, B. & Kühn, B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 138, 257-270 (2009).
    • (2009) Cell , vol.138 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3    Kühn, B.4
  • 15
    • 84873305461 scopus 로고    scopus 로고
    • Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart
    • Malliaras, K. et al. Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart. EMBO Mol. Med. 5, 191-209 (2013).
    • (2013) EMBO Mol. Med. , vol.5 , pp. 191-209
    • Malliaras, K.1
  • 16
    • 33947507392 scopus 로고    scopus 로고
    • Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties
    • Chen, X. et al. Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties. Circ. Res. 100, 536-544 (2007).
    • (2007) Circ. Res. , vol.100 , pp. 536-544
    • Chen, X.1
  • 17
    • 34547691243 scopus 로고    scopus 로고
    • Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair
    • Kühn, B. et al. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat. Med. 13, 962-969 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 962-969
    • Kühn, B.1
  • 18
    • 0035793914 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of cyclin-dependent kinase 2 increases smaller mononuclear cardiomyocytes
    • Liao, H.S. et al. Cardiac-specific overexpression of cyclin-dependent kinase 2 increases smaller mononuclear cardiomyocytes. Circ. Res. 88, 443-450 (2001).
    • (2001) Circ. Res. , vol.88 , pp. 443-450
    • Liao, H.S.1
  • 19
    • 84877775012 scopus 로고    scopus 로고
    • Meis1 regulates postnatal cardiomyocyte cell cycle arrest
    • Mahmoud, A.I. et al. Meis1 regulates postnatal cardiomyocyte cell cycle arrest. Nature 497, 249-253 (2013).
    • (2013) Nature , vol.497 , pp. 249-253
    • Mahmoud, A.I.1
  • 20
    • 75649122259 scopus 로고    scopus 로고
    • A high-resolution association mapping panel for the dissection of complex traits in mice
    • Bennett, B.J. et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res. 20, 281-290 (2010).
    • (2010) Genome Res. , vol.20 , pp. 281-290
    • Bennett, B.J.1
  • 21
    • 84953295344 scopus 로고    scopus 로고
    • Genetic architecture of atherosclerosis in mice: A systems genetics analysis of common inbred strains
    • Bennett, B.J. et al. Genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains. PLoS Genet. 11, e1005711 (2015).
    • (2015) PLoS Genet. , vol.11 , pp. e1005711
    • Bennett, B.J.1
  • 22
    • 79956334658 scopus 로고    scopus 로고
    • Heart regeneration
    • Laflamme, M.A. & Murry, C.E. Heart regeneration. Nature 473, 326-335 (2011).
    • (2011) Nature , vol.473 , pp. 326-335
    • Laflamme, M.A.1    Murry, C.E.2
  • 23
    • 84893392373 scopus 로고    scopus 로고
    • High fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure
    • Brainard, R.E. et al. High fat feeding in mice is insufficient to induce cardiac dysfunction and does not exacerbate heart failure. PLoS One 8, e83174 (2013).
    • (2013) PLoS One , vol.8 , pp. e83174
    • Brainard, R.E.1
  • 24
    • 84930477004 scopus 로고    scopus 로고
    • When bigger is better: The role of polyploidy in organogenesis
    • Orr-Weaver, T.L. When bigger is better: the role of polyploidy in organogenesis. Trends Genet. 31, 307-315 (2015).
    • (2015) Trends Genet. , vol.31 , pp. 307-315
    • Orr-Weaver, T.L.1
  • 25
    • 84894333148 scopus 로고    scopus 로고
    • The cardiomyocyte cell cycle in hypertrophy, tissue homeostasis, and regeneration
    • Zebrowski, D.C. & Engel, F.B. The cardiomyocyte cell cycle in hypertrophy, tissue homeostasis, and regeneration. Rev. Physiol. Biochem. Pharmacol. 165, 67-96 (2013).
    • (2013) Rev. Physiol. Biochem. Pharmacol. , vol.165 , pp. 67-96
    • Zebrowski, D.C.1    Engel, F.B.2
  • 26
    • 78649462103 scopus 로고    scopus 로고
    • Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover
    • Bergmann, O. et al. Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover. Exp. Cell Res. 317, 188-194 (2011).
    • (2011) Exp. Cell Res. , vol.317 , pp. 188-194
    • Bergmann, O.1
  • 27
    • 84877105755 scopus 로고    scopus 로고
    • Contribution of bone marrow-derived hematopoietic stem/progenitor cells to the generation of donor-marker+ cardiomyocytes in vivo
    • Fukata, M. et al. Contribution of bone marrow-derived hematopoietic stem/progenitor cells to the generation of donor-marker+ cardiomyocytes in vivo. PLoS One 8, e62506 (2013).
    • (2013) PLoS One , vol.8 , pp. e62506
    • Fukata, M.1
  • 28
    • 84900560043 scopus 로고    scopus 로고
    • C-kit+ cells minimally contribute cardiomyocytes to the heart
    • van Berlo, J.H. et al. c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature 509, 337-341 (2014).
    • (2014) Nature , vol.509 , pp. 337-341
    • Van Berlo, J.H.1
  • 29
    • 84924172260 scopus 로고    scopus 로고
    • Circulating cells contribute to cardiomyocyte regeneration after injury
    • Wu, J.M.F. et al. Circulating cells contribute to cardiomyocyte regeneration after injury. Circ. Res. 116, 633-641 (2015).
    • (2015) Circ. Res. , vol.116 , pp. 633-641
    • Wu, J.M.F.1
  • 30
    • 84867332713 scopus 로고    scopus 로고
    • Hybrid mouse diversity panel: A panel of inbred mouse strains suitable for analysis of complex genetic traits
    • Ghazalpour, A. et al. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm. Genome 23, 680-692 (2012).
    • (2012) Mamm. Genome , vol.23 , pp. 680-692
    • Ghazalpour, A.1
  • 31
    • 0038275985 scopus 로고    scopus 로고
    • Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin i
    • Zhao, Y. et al. Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. J. Mol. Med. (Berl.) 81, 297-304 (2003).
    • (2003) J. Mol. Med. (Berl.) , vol.81 , pp. 297-304
    • Zhao, Y.1
  • 32
    • 70349684832 scopus 로고    scopus 로고
    • Tnni3k modifies disease progression in murine models of cardiomyopathy
    • Wheeler, F.C. et al. Tnni3k modifies disease progression in murine models of cardiomyopathy. PLoS Genet. 5, e1000647 (2009).
    • (2009) PLoS Genet. , vol.5 , pp. e1000647
    • Wheeler, F.C.1
  • 33
    • 84872010658 scopus 로고    scopus 로고
    • Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction
    • Lodder, E.M. et al. Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction. PLoS Genet. 8, e1003113 (2012).
    • (2012) PLoS Genet. , vol.8 , pp. e1003113
    • Lodder, E.M.1
  • 34
    • 84886416217 scopus 로고    scopus 로고
    • Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart
    • Vagnozzi, R.J. et al. Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart. Sci. Transl. Med. 5, 207ra141 (2013).
    • (2013) Sci. Transl. Med. , vol.5 , pp. 207ra141
    • Vagnozzi, R.J.1
  • 35
    • 84870202567 scopus 로고    scopus 로고
    • Cardiac regenerative capacity and mechanisms
    • Kikuchi, K. & Poss, K.D. Cardiac regenerative capacity and mechanisms. Annu. Rev. Cell Dev. Biol. 28, 719-741 (2012).
    • (2012) Annu. Rev. Cell Dev. Biol. , vol.28 , pp. 719-741
    • Kikuchi, K.1    Poss, K.D.2
  • 36
    • 84982253941 scopus 로고    scopus 로고
    • Analysis of protein-coding genetic variation in 60,706 humans
    • Lek, M. et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature 536, 285-291 (2016).
    • (2016) Nature , vol.536 , pp. 285-291
    • Lek, M.1
  • 37
    • 85007028930 scopus 로고    scopus 로고
    • Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study
    • Dewey, F.E. et al. Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study. Science 354, 1549 (2016).
    • (2016) Science , vol.354 , pp. 1549
    • Dewey, F.E.1
  • 38
    • 0019186806 scopus 로고
    • Predictors of clinical course, coronary anatomy and left ventricular function after recovery from acute myocardial infarction
    • Taylor, G.J. et al. Predictors of clinical course, coronary anatomy and left ventricular function after recovery from acute myocardial infarction. Circulation 62, 960-970 (1980).
    • (1980) Circulation , vol.62 , pp. 960-970
    • Taylor, G.J.1
  • 39
    • 0023219810 scopus 로고
    • Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction
    • White, H.D. et al. Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 76, 44-51 (1987).
    • (1987) Circulation , vol.76 , pp. 44-51
    • White, H.D.1
  • 40
    • 84928938582 scopus 로고    scopus 로고
    • ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation
    • D'Uva, G. et al. ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation. Nat. Cell Biol. 17, 627-638 (2015).
    • (2015) Nat. Cell Biol. , vol.17 , pp. 627-638
    • D'Uva, G.1
  • 41
    • 84899533827 scopus 로고    scopus 로고
    • The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response
    • Puente, B.N. et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell 157, 565-579 (2014).
    • (2014) Cell , vol.157 , pp. 565-579
    • Puente, B.N.1
  • 42
    • 36448937132 scopus 로고    scopus 로고
    • AOP-1 interacts with cardiac-specific protein kinase TNNI3K and down-regulates its kinase activity
    • Feng, Y. et al. AOP-1 interacts with cardiac-specific protein kinase TNNI3K and down-regulates its kinase activity. Biochemistry (Mosc.) 72, 1199-1204 (2007).
    • (2007) Biochemistry (Mosc.) , vol.72 , pp. 1199-1204
    • Feng, Y.1
  • 43
    • 84871716646 scopus 로고    scopus 로고
    • Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction
    • Tang, H., Xiao, K., Mao, L., Rockman, H.A. & Marchuk, D.A. Overexpression of TNNI3K, a cardiac-specific MAPKKK, promotes cardiac dysfunction. J. Mol. Cell. Cardiol. 54, 101-111 (2013).
    • (2013) J. Mol. Cell. Cardiol. , vol.54 , pp. 101-111
    • Tang, H.1    Xiao, K.2    Mao, L.3    Rockman, H.A.4    Marchuk, D.A.5
  • 44
    • 84911374570 scopus 로고    scopus 로고
    • TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy
    • Theis, J.L. et al. TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy. Hum. Mol. Genet. 23, 5793-5804 (2014).
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 5793-5804
    • Theis, J.L.1
  • 45
    • 84928252599 scopus 로고    scopus 로고
    • Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia
    • Xi, Y. et al. Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia. Int. J. Cardiol. 185, 114-116 (2015).
    • (2015) Int. J. Cardiol. , vol.185 , pp. 114-116
    • Xi, Y.1
  • 46
    • 84943395049 scopus 로고    scopus 로고
    • High-density genotypes of inbred mouse strains: Improved power and precision of association mapping
    • Rau, C.D. et al. High-density genotypes of inbred mouse strains: improved power and precision of association mapping. G3 (Bethesda) 5, 2021-2026 (2015).
    • (2015) G3 (Bethesda) , vol.5 , pp. 2021-2026
    • Rau, C.D.1
  • 47
    • 84870527707 scopus 로고    scopus 로고
    • Comparison of co-expression measures: Mutual information, correlation, and model based indices
    • Song, L., Langfelder, P. & Horvath, S. Comparison of co-expression measures: mutual information, correlation, and model based indices. BMC Bioinformatics 13, 328 (2012).
    • (2012) BMC Bioinformatics , vol.13 , pp. 328
    • Song, L.1    Langfelder, P.2    Horvath, S.3
  • 48
    • 85027929606 scopus 로고    scopus 로고
    • Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization
    • Denholtz, M. et al. Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization. Cell Stem Cell 13, 602-616 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 602-616
    • Denholtz, M.1
  • 49
    • 78650696123 scopus 로고    scopus 로고
    • A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse
    • Gao, E. et al. A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse. Circ. Res. 107, 1445-1453 (2010).
    • (2010) Circ. Res. , vol.107 , pp. 1445-1453
    • Gao, E.1
  • 50
    • 36448963734 scopus 로고    scopus 로고
    • The Tol2kit: A multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
    • Kwan, K.M. et al. The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev. Dyn. 236, 3088-3099 (2007).
    • (2007) Dev. Dyn. , vol.236 , pp. 3088-3099
    • Kwan, K.M.1
  • 51
    • 84883859197 scopus 로고    scopus 로고
    • Isolation and in vitro culture of primary cardiomyocytes from adult zebrafish hearts
    • Sander, V., Suñe, G., Jopling, C., Morera, C. & Izpisua Belmonte, J.C. Isolation and in vitro culture of primary cardiomyocytes from adult zebrafish hearts. Nat. Protoc. 8, 800-809 (2013).
    • (2013) Nat. Protoc. , vol.8 , pp. 800-809
    • Sander, V.1    Suñe, G.2    Jopling, C.3    Morera, C.4    Izpisua Belmonte, J.C.5
  • 52
    • 84879473619 scopus 로고    scopus 로고
    • Igf signaling is required for cardiomyocyte proliferation during zebrafish heart development and regeneration
    • Huang, Y. et al. Igf signaling is required for cardiomyocyte proliferation during zebrafish heart development and regeneration. PLoS One 8, e67266 (2013).
    • (2013) PLoS One , vol.8 , pp. e67266
    • Huang, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.