Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction

PLoS Genetics

Volumn 8, Issue 12, 2012, Pages

  Lodder, Elisabeth M ^a   Scicluna, Brendon P ^a   Milano, Annalisa ^a   Sun, Albert Y ^b   Tang, Hao ^b   Remme, Carol Ann ^a   Moerland, Perry D ^a   Tanck, Michael W T ^a   Pitt, Geoffrey S ^b   Marchuk, Douglas A ^b   Bezzina, Connie R ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE; PROTEIN TNNI3K; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ELECTROCARDIOGRAPHY; GENE; GENE MAPPING; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC CORRELATION; GENOTYPE; HAPLOTYPE; HEART CONTRACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROGENY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE TRAIT LOCUS; TNNI3K GENE; WILD TYPE;

ANIMALS; ARRHYTHMIAS, CARDIAC; ATRIAL FIBRILLATION; CHROMOSOME MAPPING; ELECTROCARDIOGRAPHY; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOME; HAPLOTYPES; HEART CONDUCTION SYSTEM; HEART RATE; HUMANS; MICE; MICE, INBRED DBA; PROTEIN KINASES; QUANTITATIVE TRAIT LOCI;

MURINAE; MUS;

EID: 84872010658     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003113     Document Type: Article

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