-
1
-
-
0015452867
-
Expression of diphtheria toxin genes carried by integrated and nonintegrated phage beta
-
Gill DM, Uchida T, Singer RA Expression of diphtheria toxin genes carried by integrated and nonintegrated phage beta. Virology 1972, 50:664-668.
-
(1972)
Virology
, vol.50
, pp. 664-668
-
-
Gill, D.M.1
Uchida, T.2
Singer, R.A.3
-
2
-
-
0034107745
-
Biology and molecular epidemiology of diphtheria toxin and the tox gene
-
Holmes RK Biology and molecular epidemiology of diphtheria toxin and the tox gene. J Infect Dis 2000, 181(Suppl. 1):S156-S167.
-
(2000)
J Infect Dis
, vol.181
, pp. S156-S167
-
-
Holmes, R.K.1
-
3
-
-
26844562168
-
Corynebacterium diphtheriae
-
Baron S, editor. University of Texas Medical Branch at Galveston, TX;
-
Murphy JR. Corynebacterium diphtheriae. In: Baron S, editor. Medical microbiology. University of Texas Medical Branch at Galveston, TX; 1996.
-
(1996)
Medical microbiology
-
-
Murphy, J.R.1
-
4
-
-
0018140198
-
Evidence that the regulation of diphtheria toxin production is directed at the level of transcription
-
Murphy JR, Michel JL, Teng M Evidence that the regulation of diphtheria toxin production is directed at the level of transcription. J Bacteriol 1978, 135:511-516.
-
(1978)
J Bacteriol
, vol.135
, pp. 511-516
-
-
Murphy, J.R.1
Michel, J.L.2
Teng, M.3
-
5
-
-
41649113814
-
The designing of anti-diphtheria serotherapy at the Institut Pasteur (1888-1900): the role of a supranational network of microbiologists
-
Gachelin G The designing of anti-diphtheria serotherapy at the Institut Pasteur (1888-1900): the role of a supranational network of microbiologists. Dynamis 2007, 27:45-62.
-
(2007)
Dynamis
, vol.27
, pp. 45-62
-
-
Gachelin, G.1
-
6
-
-
0022341498
-
Diphtheria in the United States, 1971-81
-
Chen RT, Broome CV, Weinstein RA, Weaver R, Tsai TF Diphtheria in the United States, 1971-81. Am J Public Health 1985, 75:1393-1397.
-
(1985)
Am J Public Health
, vol.75
, pp. 1393-1397
-
-
Chen, R.T.1
Broome, C.V.2
Weinstein, R.A.3
Weaver, R.4
Tsai, T.F.5
-
7
-
-
0034097154
-
Successful control of epidemic diphtheria in the states of the former Union of Soviet Socialist Republics: lessons learned
-
Dittmann S, Wharton M, Vitek C, Ciotti M, Galazka A, Guichard S, et al. Successful control of epidemic diphtheria in the states of the former Union of Soviet Socialist Republics: lessons learned. J Infect Dis 2000, 181(Suppl. 1):S10-S22.
-
(2000)
J Infect Dis
, vol.181
, pp. S10-S22
-
-
Dittmann, S.1
Wharton, M.2
Vitek, C.3
Ciotti, M.4
Galazka, A.5
Guichard, S.6
-
8
-
-
0023867719
-
Molecular epidemiology of the 1984-1986 outbreak of diphtheria in Sweden
-
Rappuoli R, Perugini M, Falsen E Molecular epidemiology of the 1984-1986 outbreak of diphtheria in Sweden. N Engl J Med 1988, 318:12-14.
-
(1988)
N Engl J Med
, vol.318
, pp. 12-14
-
-
Rappuoli, R.1
Perugini, M.2
Falsen, E.3
-
9
-
-
0031565541
-
Infections with Corynebacterium diphtheriae-Changing epidemiology and clinical manifestations. Report of the third international meeting of the European Laboratory Working Group on Diphtheria (ELWGD), Institut Pasteur, Paris 7-8 June 1996
-
Gilbert L Infections with Corynebacterium diphtheriae-Changing epidemiology and clinical manifestations. Report of the third international meeting of the European Laboratory Working Group on Diphtheria (ELWGD), Institut Pasteur, Paris 7-8 June 1996. Commun Dis Intell 1997, 21:161-164.
-
(1997)
Commun Dis Intell
, vol.21
, pp. 161-164
-
-
Gilbert, L.1
-
10
-
-
84900548440
-
Diphtheria outbreak with high mortality in northeastern Nigeria
-
Besa NC, Coldiron ME, Bakri A, Raji A, Nsuami MJ, Rousseau C, et al. Diphtheria outbreak with high mortality in northeastern Nigeria. Epidemiol Infect 2014, 142:797-802.
-
(2014)
Epidemiol Infect
, vol.142
, pp. 797-802
-
-
Besa, N.C.1
Coldiron, M.E.2
Bakri, A.3
Raji, A.4
Nsuami, M.J.5
Rousseau, C.6
-
11
-
-
0034878448
-
Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century
-
Collier RJ Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century. Toxicon 2001, 39:1793-1803.
-
(2001)
Toxicon
, vol.39
, pp. 1793-1803
-
-
Collier, R.J.1
-
13
-
-
0000078012
-
Contribution a l'etude de la diphterie
-
Roux E, Yersin A Contribution a l'etude de la diphterie. Ann Inst Pasteur 1888, 2:620-629.
-
(1888)
Ann Inst Pasteur
, vol.2
, pp. 620-629
-
-
Roux, E.1
Yersin, A.2
-
14
-
-
85003983917
-
Untersuchungen uber das Zustandekommen der Diphtherie-Immunitat bei Theiren
-
Behring E Untersuchungen uber das Zustandekommen der Diphtherie-Immunitat bei Theiren. Deutsche Medizinische Wochenschrift 1890, 16:1145.
-
(1890)
Deutsche Medizinische Wochenschrift
, vol.16
, pp. 1145
-
-
Behring, E.1
-
15
-
-
0025076421
-
Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine
-
Wilson BA, Reich KA, Weinstein BR, Collier RJ Active-site mutations of diphtheria toxin: effects of replacing glutamic acid-148 with aspartic acid, glutamine, or serine. Biochemistry 1990, 29:8643-8651.
-
(1990)
Biochemistry
, vol.29
, pp. 8643-8651
-
-
Wilson, B.A.1
Reich, K.A.2
Weinstein, B.R.3
Collier, R.J.4
-
16
-
-
0026583716
-
Behring's discovery of diphtheria and tetanus antitoxins [see comments]
-
Grundbacher FJ Behring's discovery of diphtheria and tetanus antitoxins [see comments]. Immunol Today 1992, 13:188-190.
-
(1992)
Immunol Today
, vol.13
, pp. 188-190
-
-
Grundbacher, F.J.1
-
17
-
-
0001459154
-
Sur le pouvoir floculant et sur les proprietes immunisantes d'une toxine diphterique rendue anatoxique (anatoxine)
-
Ramon G Sur le pouvoir floculant et sur les proprietes immunisantes d'une toxine diphterique rendue anatoxique (anatoxine). C R Acad Sci 1923, 177:1330-1338.
-
(1923)
C R Acad Sci
, vol.177
, pp. 1330-1338
-
-
Ramon, G.1
-
18
-
-
0001079281
-
The purification and concentration of diphtheria toxin
-
Eaton MD The purification and concentration of diphtheria toxin. J Bacteriol 1936, 31:347.
-
(1936)
J Bacteriol
, vol.31
, pp. 347
-
-
Eaton, M.D.1
-
19
-
-
0000674879
-
Diphtheria toxin-i: isolation and characterization of a toxic protein from C. diphtheriae filtrates
-
Pappenheimer AM Diphtheria toxin-i: isolation and characterization of a toxic protein from C. diphtheriae filtrates. J Biol Chem 1937, 125:543.
-
(1937)
J Biol Chem
, vol.125
, pp. 543
-
-
Pappenheimer, A.M.1
-
20
-
-
0021113322
-
Nucleotide sequence and expression of the diphtheria tox228 gene in Escherichia coli
-
Kaczorek M, Delpeyroux F, Chenciner N, Streeck RE, Murphy JR, Boquet P, et al. Nucleotide sequence and expression of the diphtheria tox228 gene in Escherichia coli. Science 1983, 221:855-858.
-
(1983)
Science
, vol.221
, pp. 855-858
-
-
Kaczorek, M.1
Delpeyroux, F.2
Chenciner, N.3
Streeck, R.E.4
Murphy, J.R.5
Boquet, P.6
-
21
-
-
0005301151
-
Nucleotide sequence of the structural gene for diphtheria toxin carried by Corynebacteriophage beta
-
Greenfield L, Bjorn MJ, Horn G, Fong D, Buck GA, Collier RJ, et al. Nucleotide sequence of the structural gene for diphtheria toxin carried by Corynebacteriophage beta. Proc Natl Acad Sci USA 1983, 80:6853-6857.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 6853-6857
-
-
Greenfield, L.1
Bjorn, M.J.2
Horn, G.3
Fong, D.4
Buck, G.A.5
Collier, R.J.6
-
22
-
-
0021101239
-
The complete nucleotide sequence of the gene coding for diphtheria toxin in the Corynephage omega (tox+) genome
-
Ratti G, Rappuoli R, Giannini G The complete nucleotide sequence of the gene coding for diphtheria toxin in the Corynephage omega (tox+) genome. Nucleic Acids Res 1983, 11:6589-6595.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 6589-6595
-
-
Ratti, G.1
Rappuoli, R.2
Giannini, G.3
-
23
-
-
0026552246
-
The crystal structure of diphtheria toxin
-
Choe S, Bennett MJ, Fujii G, Curmi PM, Kantardjieff KA, Collier RJ, et al. The crystal structure of diphtheria toxin. Nature 1992, 357:216-222.
-
(1992)
Nature
, vol.357
, pp. 216-222
-
-
Choe, S.1
Bennett, M.J.2
Fujii, G.3
Curmi, P.M.4
Kantardjieff, K.A.5
Collier, R.J.6
-
24
-
-
0008530328
-
Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein
-
Murphy JR, Bishai W, Borowski M, Miyanohara A, Boyd J, Nagle S Genetic construction, expression, and melanoma-selective cytotoxicity of a diphtheria toxin-related alpha-melanocyte-stimulating hormone fusion protein. Proc Natl Acad Sci USA 1986, 83:8258-8262.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 8258-8262
-
-
Murphy, J.R.1
Bishai, W.2
Borowski, M.3
Miyanohara, A.4
Boyd, J.5
Nagle, S.6
-
25
-
-
0015124068
-
Mutation in the structural gene for diphtheria toxin carried by temperate phage
-
Uchida T, Gill DM, Pappenheimer AM Mutation in the structural gene for diphtheria toxin carried by temperate phage. Nat New Biol 1971, 233:8-11.
-
(1971)
Nat New Biol
, vol.233
, pp. 8-11
-
-
Uchida, T.1
Gill, D.M.2
Pappenheimer, A.M.3
-
26
-
-
1842536410
-
Analysis of genes that encode DtxR-like transcriptional regulators in pathogenic and saprophytic corynebacterial species
-
Oram DM, Avdalovic A, Holmes RK Analysis of genes that encode DtxR-like transcriptional regulators in pathogenic and saprophytic corynebacterial species. Infect Immun 2004, 72:1885-1895.
-
(2004)
Infect Immun
, vol.72
, pp. 1885-1895
-
-
Oram, D.M.1
Avdalovic, A.2
Holmes, R.K.3
-
27
-
-
0032581662
-
Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex
-
White A, Ding X, vanderSpek JC, Murphy JR, Ringe D Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex. Nature 1998, 394:502-506.
-
(1998)
Nature
, vol.394
, pp. 502-506
-
-
White, A.1
Ding, X.2
vanderSpek, J.C.3
Murphy, J.R.4
Ringe, D.5
-
28
-
-
0028006022
-
Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron
-
Schmitt MP, Holmes RK Cloning, sequence, and footprint analysis of two promoter/operators from Corynebacterium diphtheriae that are regulated by the diphtheria toxin repressor (DtxR) and iron. J Bacteriol 1994, 176:1141-1149.
-
(1994)
J Bacteriol
, vol.176
, pp. 1141-1149
-
-
Schmitt, M.P.1
Holmes, R.K.2
-
29
-
-
0026667137
-
Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence
-
Tao X, Boyd J, Murphy JR Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence. Proc Natl Acad Sci USA 1992, 89:5897-5901.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5897-5901
-
-
Tao, X.1
Boyd, J.2
Murphy, J.R.3
-
30
-
-
0027968843
-
Determination of the minimal essential nucleotide sequence for diphtheria tox repressor binding by in vitro affinity selection
-
Tao X, Murphy JR Determination of the minimal essential nucleotide sequence for diphtheria tox repressor binding by in vitro affinity selection. Proc Natl Acad Sci USA 1994, 91:9646-9650.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9646-9650
-
-
Tao, X.1
Murphy, J.R.2
-
31
-
-
0000868851
-
Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain
-
Pohl E, Holmes RK, Hol WG Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain. J Mol Biol 1999, 292:653-667.
-
(1999)
J Mol Biol
, vol.292
, pp. 653-667
-
-
Pohl, E.1
Holmes, R.K.2
Hol, W.G.3
-
32
-
-
0028077639
-
Refined structure of monomeric diphtheria toxin at 2.3 Å resolution
-
Bennett MJ, Eisenberg D Refined structure of monomeric diphtheria toxin at 2.3 Å resolution. Protein Sci 1994, 3:1464-1475.
-
(1994)
Protein Sci
, vol.3
, pp. 1464-1475
-
-
Bennett, M.J.1
Eisenberg, D.2
-
33
-
-
0028077637
-
Refined structure of dimeric diphtheria toxin at 2.0 Å resolution
-
Bennett MJ, Choe S, Eisenberg D Refined structure of dimeric diphtheria toxin at 2.0 Å resolution. Protein Sci 1994, 3:1444-1463.
-
(1994)
Protein Sci
, vol.3
, pp. 1444-1463
-
-
Bennett, M.J.1
Choe, S.2
Eisenberg, D.3
-
34
-
-
0030031666
-
Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide
-
Bell CE, Eisenberg D Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide. Biochemistry 1996, 35:1137-1149.
-
(1996)
Biochemistry
, vol.35
, pp. 1137-1149
-
-
Bell, C.E.1
Eisenberg, D.2
-
35
-
-
0031305240
-
Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor
-
Louie GV, Yang W, Bowman ME, Choe S Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor. Mol Cell 1997, 1:67-78.
-
(1997)
Mol Cell
, vol.1
, pp. 67-78
-
-
Louie, G.V.1
Yang, W.2
Bowman, M.E.3
Choe, S.4
-
36
-
-
11144244704
-
Structural features common to intracellularly acting toxins from bacteria
-
Menetrey J, Gillet D, Menez A Structural features common to intracellularly acting toxins from bacteria. Toxicon 2005, 45:129-137.
-
(2005)
Toxicon
, vol.45
, pp. 129-137
-
-
Menetrey, J.1
Gillet, D.2
Menez, A.3
-
37
-
-
0027533260
-
Globin fold in a bacterial toxin
-
Holm L, Sander C Globin fold in a bacterial toxin. Nature 1993, 361:309.
-
(1993)
Nature
, vol.361
, pp. 309
-
-
Holm, L.1
Sander, C.2
-
38
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
Reed JC Double identity for proteins of the Bcl-2 family. Nature 1997, 387:773-776.
-
(1997)
Nature
, vol.387
, pp. 773-776
-
-
Reed, J.C.1
-
39
-
-
0026747170
-
Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor
-
Naglich JG, Metherall JE, Russell DW, Eidels L Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 1992, 69:1051-1061.
-
(1992)
Cell
, vol.69
, pp. 1051-1061
-
-
Naglich, J.G.1
Metherall, J.E.2
Russell, D.W.3
Eidels, L.4
-
40
-
-
0027495717
-
Evidence for involvement of furin in cleavage and activation of diphtheria toxin
-
Tsuneoka M, Nakayama K, Hatsuzawa K, Komada M, Kitamura N, Mekada E Evidence for involvement of furin in cleavage and activation of diphtheria toxin. J Biol Chem 1993, 268:26461-26465.
-
(1993)
J Biol Chem
, vol.268
, pp. 26461-26465
-
-
Tsuneoka, M.1
Nakayama, K.2
Hatsuzawa, K.3
Komada, M.4
Kitamura, N.5
Mekada, E.6
-
41
-
-
0019963806
-
Receptor-mediated endocytosis of diphtheria toxin by cells in culture
-
Keen JH, Maxfield FR, Hardegree MC, Habig WH Receptor-mediated endocytosis of diphtheria toxin by cells in culture. Proc Natl Acad Sci USA 1982, 79:2912-2916.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 2912-2916
-
-
Keen, J.H.1
Maxfield, F.R.2
Hardegree, M.C.3
Habig, W.H.4
-
42
-
-
0022005540
-
Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin, but not that of ricin toxin
-
Moya M, Dautry-Varsat A, Goud B, Louvard D, Boquet P Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin, but not that of ricin toxin. J Cell Biol 1985, 101:548-559.
-
(1985)
J Cell Biol
, vol.101
, pp. 548-559
-
-
Moya, M.1
Dautry-Varsat, A.2
Goud, B.3
Louvard, D.4
Boquet, P.5
-
43
-
-
0022388616
-
Receptor-mediated entry of diphtheria toxin into monkey kidney (Vero) cells: electron microscopic evaluation
-
Morris RE, Gerstein AS, Bonventre PF, Saelinger CB Receptor-mediated entry of diphtheria toxin into monkey kidney (Vero) cells: electron microscopic evaluation. Infect Immun 1985, 50:721-727.
-
(1985)
Infect Immun
, vol.50
, pp. 721-727
-
-
Morris, R.E.1
Gerstein, A.S.2
Bonventre, P.F.3
Saelinger, C.B.4
-
44
-
-
0037044842
-
Membrane protein insertion regulated by bringing electrostatic and hydrophobic interactions into play: a case study with the translocation domain of the diphtheria toxin
-
Chenal A, Savarin P, Nizard P, Guillain F, Gillet D, Forge V Membrane protein insertion regulated by bringing electrostatic and hydrophobic interactions into play: a case study with the translocation domain of the diphtheria toxin. J Biol Chem 2002, 277:43425-43432.
-
(2002)
J Biol Chem
, vol.277
, pp. 43425-43432
-
-
Chenal, A.1
Savarin, P.2
Nizard, P.3
Guillain, F.4
Gillet, D.5
Forge, V.6
-
45
-
-
0026492389
-
How bacterial protein toxins enter cells; The role of partial unfolding in membrane translocation
-
London E How bacterial protein toxins enter cells; The role of partial unfolding in membrane translocation. Mol Microbiol 1992, 6:3277-3282.
-
(1992)
Mol Microbiol
, vol.6
, pp. 3277-3282
-
-
London, E.1
-
46
-
-
0026574178
-
Diphtheria toxin: membrane interaction and membrane translocation
-
London E Diphtheria toxin: membrane interaction and membrane translocation. Biochim Biophys Acta 1992, 1113:25-51.
-
(1992)
Biochim Biophys Acta
, vol.1113
, pp. 25-51
-
-
London, E.1
-
47
-
-
84882817873
-
The translocation domain from diphtheria toxin: interaction with membranes and application as a membrane anchor for cancer vaccines
-
Research Signpost, Trivandrum, India, S.G. Pandalai (Ed.)
-
Chenal A, Babon A, Perier A, Nizard P, Forge V, Gillet D The translocation domain from diphtheria toxin: interaction with membranes and application as a membrane anchor for cancer vaccines. Recent research developments in biochemistry 2003, 985-1000. Research Signpost, Trivandrum, India. S.G. Pandalai (Ed.).
-
(2003)
Recent research developments in biochemistry
, pp. 985-1000
-
-
Chenal, A.1
Babon, A.2
Perier, A.3
Nizard, P.4
Forge, V.5
Gillet, D.6
-
48
-
-
0019287379
-
The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement
-
Draper RK, Simon MI The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement. J Cell Biol 1980, 87:849-854.
-
(1980)
J Cell Biol
, vol.87
, pp. 849-854
-
-
Draper, R.K.1
Simon, M.I.2
-
49
-
-
0019811089
-
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
-
Sandvig K, Olsnes S Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule. J Biol Chem 1981, 256:9068-9076.
-
(1981)
J Biol Chem
, vol.256
, pp. 9068-9076
-
-
Sandvig, K.1
Olsnes, S.2
-
50
-
-
0019271816
-
Diphtheria toxin entry into cells is facilitated by low pH
-
Sandvig K, Olsnes S Diphtheria toxin entry into cells is facilitated by low pH. J Cell Biol 1980, 87:828-832.
-
(1980)
J Cell Biol
, vol.87
, pp. 828-832
-
-
Sandvig, K.1
Olsnes, S.2
-
51
-
-
0031031848
-
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
-
Lemichez E, Bomsel M, Devilliers G, vanderSpek J, Murphy JR, Lukianov EV, et al. Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery. Mol Microbiol 1997, 23:445-457.
-
(1997)
Mol Microbiol
, vol.23
, pp. 445-457
-
-
Lemichez, E.1
Bomsel, M.2
Devilliers, G.3
vanderSpek, J.4
Murphy, J.R.5
Lukianov, E.V.6
-
52
-
-
81055136733
-
Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain
-
Chassaing A, Pichard S, Araye-Guet A, Barbier J, Forge V, Gillet D Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain. FEBS J 2011, 278:4516-4525.
-
(2011)
FEBS J
, vol.278
, pp. 4516-4525
-
-
Chassaing, A.1
Pichard, S.2
Araye-Guet, A.3
Barbier, J.4
Forge, V.5
Gillet, D.6
-
53
-
-
0029152161
-
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
-
Falnes PO, Olsnes S Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment. J Biol Chem 1995, 270:20787-20793.
-
(1995)
J Biol Chem
, vol.270
, pp. 20787-20793
-
-
Falnes, P.O.1
Olsnes, S.2
-
54
-
-
0345668477
-
The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex
-
Ratts R, Zeng H, Berg EA, Blue C, McComb ME, Costello CE, et al. The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex. J Cell Biol 2003, 160:1139-1150.
-
(2003)
J Cell Biol
, vol.160
, pp. 1139-1150
-
-
Ratts, R.1
Zeng, H.2
Berg, E.A.3
Blue, C.4
McComb, M.E.5
Costello, C.E.6
-
55
-
-
0014429772
-
Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis
-
Honjo T, Nishizuka Y, Hayaishi O Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J Biol Chem 1968, 243:3553-3555.
-
(1968)
J Biol Chem
, vol.243
, pp. 3553-3555
-
-
Honjo, T.1
Nishizuka, Y.2
Hayaishi, O.3
-
56
-
-
0014202360
-
Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors
-
Collier RJ Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors. J Mol Biol 1967, 25:83-98.
-
(1967)
J Mol Biol
, vol.25
, pp. 83-98
-
-
Collier, R.J.1
-
57
-
-
0014665802
-
Diphtheria toxin subunit active in vitro
-
Collier RJ, Cole HA Diphtheria toxin subunit active in vitro. Science 1969, 164:1179-1181.
-
(1969)
Science
, vol.164
, pp. 1179-1181
-
-
Collier, R.J.1
Cole, H.A.2
-
58
-
-
0019333178
-
ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products
-
Van Ness BG, Howard JB, Bodley JW ADP-ribosylation of elongation factor 2 by diphtheria toxin. NMR spectra and proposed structures of ribosyl-diphthamide and its hydrolysis products. J Biol Chem 1980, 255:10710-10716.
-
(1980)
J Biol Chem
, vol.255
, pp. 10710-10716
-
-
Van Ness, B.G.1
Howard, J.B.2
Bodley, J.W.3
-
59
-
-
0019333247
-
ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products
-
Van Ness BG, Howard JB, Bodley JW ADP-ribosylation of elongation factor 2 by diphtheria toxin. Isolation and properties of the novel ribosyl-amino acid and its hydrolysis products. J Biol Chem 1980, 255:10717-10720.
-
(1980)
J Biol Chem
, vol.255
, pp. 10717-10720
-
-
Van Ness, B.G.1
Howard, J.B.2
Bodley, J.W.3
-
60
-
-
0025904265
-
A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
-
Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 1991, 251:936-939.
-
(1991)
Science
, vol.251
, pp. 936-939
-
-
Higashiyama, S.1
Abraham, J.A.2
Miller, J.3
Fiddes, J.C.4
Klagsbrun, M.5
-
61
-
-
0026673961
-
Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein
-
Higashiyama S, Lau K, Besner GE, Abraham JA, Klagsbrun M Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein. J Biol Chem 1992, 267:6205-6212.
-
(1992)
J Biol Chem
, vol.267
, pp. 6205-6212
-
-
Higashiyama, S.1
Lau, K.2
Besner, G.E.3
Abraham, J.A.4
Klagsbrun, M.5
-
62
-
-
0028860250
-
Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity
-
Mitamura T, Higashiyama S, Taniguchi N, Klagsbrun M, Mekada E Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem 1995, 270:1015-1019.
-
(1995)
J Biol Chem
, vol.270
, pp. 1015-1019
-
-
Mitamura, T.1
Higashiyama, S.2
Taniguchi, N.3
Klagsbrun, M.4
Mekada, E.5
-
63
-
-
0030779109
-
Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis
-
Mitamura T, Umata T, Nakano F, Shishido Y, Toyoda T, Itai A, et al. Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis. J Biol Chem 1997, 272:27084-27090.
-
(1997)
J Biol Chem
, vol.272
, pp. 27084-27090
-
-
Mitamura, T.1
Umata, T.2
Nakano, F.3
Shishido, Y.4
Toyoda, T.5
Itai, A.6
-
64
-
-
0029893228
-
Glutamic acid 141 of the diphtheria toxin receptor (hb-EGF precursor) is critical for toxin binding and toxin sensitivity
-
Hooper KP, Eidels L Glutamic acid 141 of the diphtheria toxin receptor (hb-EGF precursor) is critical for toxin binding and toxin sensitivity. Biochem Biophys Res Commun 1996, 220:675-680.
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 675-680
-
-
Hooper, K.P.1
Eidels, L.2
-
65
-
-
0031683636
-
Toxin binding site of the diphtheria toxin receptor: loss and gain of diphtheria toxin binding of monkey and mouse heparin-binding, epidermal growth factor-like growth factor precursors by reciprocal site-directed mutagenesis
-
Cha JH, Brooke JS, Eidels L Toxin binding site of the diphtheria toxin receptor: loss and gain of diphtheria toxin binding of monkey and mouse heparin-binding, epidermal growth factor-like growth factor precursors by reciprocal site-directed mutagenesis. Mol Microbiol 1998, 29:1275-1284.
-
(1998)
Mol Microbiol
, vol.29
, pp. 1275-1284
-
-
Cha, J.H.1
Brooke, J.S.2
Eidels, L.3
-
66
-
-
0017350046
-
Response of cultured mammalian cells to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae: differential cytotoxicity
-
Middlebrook JL, Dorland RB Response of cultured mammalian cells to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae: differential cytotoxicity. Can J Microbiol 1977, 23:183-189.
-
(1977)
Can J Microbiol
, vol.23
, pp. 183-189
-
-
Middlebrook, J.L.1
Dorland, R.B.2
-
67
-
-
0027169924
-
Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and cd9 antigen
-
Brown JG, Almond BD, Naglich JG, Eidels L Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and cd9 antigen. Proc Natl Acad Sci USA 1993, 90:8184-8188.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8184-8188
-
-
Brown, J.G.1
Almond, B.D.2
Naglich, J.G.3
Eidels, L.4
-
68
-
-
80053951760
-
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis
-
Bollee G, Flamant M, Schordan S, Fligny C, Rumpel E, Milon M, et al. Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. Nat Med 2011, 17:1242-1250.
-
(2011)
Nat Med
, vol.17
, pp. 1242-1250
-
-
Bollee, G.1
Flamant, M.2
Schordan, S.3
Fligny, C.4
Rumpel, E.5
Milon, M.6
-
69
-
-
0028284810
-
Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity
-
Iwamoto R, Higashiyama S, Mitamura T, Taniguchi N, Klagsbrun M, Mekada E Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity. Embo J 1994, 13:2322-2330.
-
(1994)
Embo J
, vol.13
, pp. 2322-2330
-
-
Iwamoto, R.1
Higashiyama, S.2
Mitamura, T.3
Taniguchi, N.4
Klagsbrun, M.5
Mekada, E.6
-
70
-
-
0034629169
-
Cell surface monkey CD9 antigen is a coreceptor that increases diphtheria toxin sensitivity and diphtheria toxin receptor affinity
-
Cha JH, Brooke JS, Ivey KN, Eidels L Cell surface monkey CD9 antigen is a coreceptor that increases diphtheria toxin sensitivity and diphtheria toxin receptor affinity. J Biol Chem 2000, 275:6901-6907.
-
(2000)
J Biol Chem
, vol.275
, pp. 6901-6907
-
-
Cha, J.H.1
Brooke, J.S.2
Ivey, K.N.3
Eidels, L.4
-
71
-
-
0034674432
-
Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity
-
Nakamura K, Mitamura T, Takahashi T, Kobayashi T, Mekada E Importance of the major extracellular domain of CD9 and the epidermal growth factor (EGF)-like domain of heparin-binding EGF-like growth factor for up-regulation of binding and activity. J Biol Chem 2000, 275:18284-18290.
-
(2000)
J Biol Chem
, vol.275
, pp. 18284-18290
-
-
Nakamura, K.1
Mitamura, T.2
Takahashi, T.3
Kobayashi, T.4
Mekada, E.5
-
72
-
-
0035861966
-
CD9 amino acids critical for upregulation of diphtheria toxin binding
-
Hasuwa H, Shishido Y, Yamazaki A, Kobayashi T, Yu X, Mekada E CD9 amino acids critical for upregulation of diphtheria toxin binding. Biochem Biophys Res Commun 2001, 289:782-790.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 782-790
-
-
Hasuwa, H.1
Shishido, Y.2
Yamazaki, A.3
Kobayashi, T.4
Yu, X.5
Mekada, E.6
-
73
-
-
0018068693
-
Association of diphtheria toxin with vero cells. Demonstration of a receptor
-
Middlebrook JL, Dorland RB, Leppla SH Association of diphtheria toxin with vero cells. Demonstration of a receptor. J Biol Chem 1978, 253:7325-7330.
-
(1978)
J Biol Chem
, vol.253
, pp. 7325-7330
-
-
Middlebrook, J.L.1
Dorland, R.B.2
Leppla, S.H.3
-
74
-
-
0032551727
-
Diphtheria toxin: receptor interaction: association, dissociation, and effect of pH
-
Brooke JS, Cha JH, Eidels L Diphtheria toxin: receptor interaction: association, dissociation, and effect of pH. Biochem Biophys Res Commun 1998, 248:297-302.
-
(1998)
Biochem Biophys Res Commun
, vol.248
, pp. 297-302
-
-
Brooke, J.S.1
Cha, J.H.2
Eidels, L.3
-
75
-
-
0022511852
-
Dimeric form of diphtheria toxin: purification and characterization
-
Carroll SF, Barbieri JT, Collier RJ Dimeric form of diphtheria toxin: purification and characterization. Biochemistry 1986, 25:2425-2430.
-
(1986)
Biochemistry
, vol.25
, pp. 2425-2430
-
-
Carroll, S.F.1
Barbieri, J.T.2
Collier, R.J.3
-
76
-
-
0028152523
-
Participation of lysine 516 and phenylalanine 530 of diphtheria toxin in receptor recognition
-
Shen WH, Choe S, Eisenberg D, Collier RJ Participation of lysine 516 and phenylalanine 530 of diphtheria toxin in receptor recognition. J Biol Chem 1994, 269:29077-29084.
-
(1994)
J Biol Chem
, vol.269
, pp. 29077-29084
-
-
Shen, W.H.1
Choe, S.2
Eisenberg, D.3
Collier, R.J.4
-
77
-
-
0023205060
-
Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity
-
Greenfield L, Johnson VG, Youle RJ Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity. Science 1987, 238:536-539.
-
(1987)
Science
, vol.238
, pp. 536-539
-
-
Greenfield, L.1
Johnson, V.G.2
Youle, R.J.3
-
78
-
-
0015217337
-
Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments
-
Collier RJ, Kandel J Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments. J Biol Chem 1971, 246:1496-1503.
-
(1971)
J Biol Chem
, vol.246
, pp. 1496-1503
-
-
Collier, R.J.1
Kandel, J.2
-
79
-
-
0015217329
-
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule
-
Drazin R, Kandel J, Collier RJ Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule. J Biol Chem 1971, 246:1504-1510.
-
(1971)
J Biol Chem
, vol.246
, pp. 1504-1510
-
-
Drazin, R.1
Kandel, J.2
Collier, R.J.3
-
80
-
-
0015217293
-
Observations on the structure of diphtheria toxin
-
Gill DM, Dinius LL Observations on the structure of diphtheria toxin. J Biol Chem 1971, 246:1485-1491.
-
(1971)
J Biol Chem
, vol.246
, pp. 1485-1491
-
-
Gill, D.M.1
Dinius, L.L.2
-
81
-
-
0015217224
-
Structure-activity relationships in diphtheria toxin
-
Gill DM, Pappenheimer AM Structure-activity relationships in diphtheria toxin. J Biol Chem 1971, 246:1492-1495.
-
(1971)
J Biol Chem
, vol.246
, pp. 1492-1495
-
-
Gill, D.M.1
Pappenheimer, A.M.2
-
82
-
-
0028304478
-
Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver
-
Chiron MF, Fryling CM, FitzGerald DJ Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J Biol Chem 1994, 269:18167-18176.
-
(1994)
J Biol Chem
, vol.269
, pp. 18167-18176
-
-
Chiron, M.F.1
Fryling, C.M.2
FitzGerald, D.J.3
-
83
-
-
0028872463
-
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
-
Gordon VM, Klimpel KR, Arora N, Henderson MA, Leppla SH Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect Immun 1995, 63:82-87.
-
(1995)
Infect Immun
, vol.63
, pp. 82-87
-
-
Gordon, V.M.1
Klimpel, K.R.2
Arora, N.3
Henderson, M.A.4
Leppla, S.H.5
-
84
-
-
0033137011
-
Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain
-
Sucic JF, Moehring JM, Inocencio NM, Luchini JW, Moehring TJ Endoprotease PACE4 is Ca2+-dependent and temperature-sensitive and can partly rescue the phenotype of a furin-deficient cell strain. Biochem J 1999, 339:639-647.
-
(1999)
Biochem J
, vol.339
, pp. 639-647
-
-
Sucic, J.F.1
Moehring, J.M.2
Inocencio, N.M.3
Luchini, J.W.4
Moehring, T.J.5
-
85
-
-
0025203984
-
Cellular processing of the interleukin-2 fusion toxin DAB486-il-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194
-
Williams DP, Wen Z, Watson RS, Boyd J, Strom TB, Murphy JR Cellular processing of the interleukin-2 fusion toxin DAB486-il-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194. J Biol Chem 1990, 265:20673-20677.
-
(1990)
J Biol Chem
, vol.265
, pp. 20673-20677
-
-
Williams, D.P.1
Wen, Z.2
Watson, R.S.3
Boyd, J.4
Strom, T.B.5
Murphy, J.R.6
-
87
-
-
0027510933
-
Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol
-
Papini E, Rappuoli R, Murgia M, Montecucco C Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol. J Biol Chem 1993, 268:1567-1574.
-
(1993)
J Biol Chem
, vol.268
, pp. 1567-1574
-
-
Papini, E.1
Rappuoli, R.2
Murgia, M.3
Montecucco, C.4
-
88
-
-
0024892776
-
Cellular regulation of diphtheria toxin cell surface receptors
-
Ronnberg BJ, Middlebrook JL Cellular regulation of diphtheria toxin cell surface receptors. Toxicon 1989, 27:1377-1388.
-
(1989)
Toxicon
, vol.27
, pp. 1377-1388
-
-
Ronnberg, B.J.1
Middlebrook, J.L.2
-
89
-
-
0033547792
-
Structure and topology of diphtheria toxin R domain in lipid membranes
-
Quertenmont P, Wolff C, Wattiez R, Vander Borght P, Falmagne P, Ruysschaert JM, et al. Structure and topology of diphtheria toxin R domain in lipid membranes. Biochemistry 1999, 38:660-666.
-
(1999)
Biochemistry
, vol.38
, pp. 660-666
-
-
Quertenmont, P.1
Wolff, C.2
Wattiez, R.3
Vander Borght, P.4
Falmagne, P.5
Ruysschaert, J.M.6
-
90
-
-
0028846613
-
Immunochemical analysis shows all three domains of diphtheria toxin penetrate across model membranes
-
Tortorella D, Sesardic D, Dawes CS, London E Immunochemical analysis shows all three domains of diphtheria toxin penetrate across model membranes. J Biol Chem 1995, 270:27446-27452.
-
(1995)
J Biol Chem
, vol.270
, pp. 27446-27452
-
-
Tortorella, D.1
Sesardic, D.2
Dawes, C.S.3
London, E.4
-
91
-
-
0029869843
-
An endosomal beta cop is involved in the pH-dependent formation of transport vesicles destined for late endosomes
-
Aniento F, Gu F, Parton RG, Gruenberg J An endosomal beta cop is involved in the pH-dependent formation of transport vesicles destined for late endosomes. J Cell Biol 1996, 133:29-41.
-
(1996)
J Cell Biol
, vol.133
, pp. 29-41
-
-
Aniento, F.1
Gu, F.2
Parton, R.G.3
Gruenberg, J.4
-
92
-
-
0018167496
-
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
-
Yamaizumi M, Mekada E, Uchida T, Okada Y One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell. Cell 1978, 15:245-250.
-
(1978)
Cell
, vol.15
, pp. 245-250
-
-
Yamaizumi, M.1
Mekada, E.2
Uchida, T.3
Okada, Y.4
-
93
-
-
0034635520
-
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
-
Falnes PO, Ariansen S, Sandvig K, Olsnes S Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin. J Biol Chem 2000, 275:4363-4368.
-
(2000)
J Biol Chem
, vol.275
, pp. 4363-4368
-
-
Falnes, P.O.1
Ariansen, S.2
Sandvig, K.3
Olsnes, S.4
-
94
-
-
0028269946
-
Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain
-
Silverman JA, Mindell JA, Zhan H, Finkelstein A, Collier RJ Structure-function relationships in diphtheria toxin channels: I. Determining a minimal channel-forming domain. J Membr Biol 1994, 137:17-28.
-
(1994)
J Membr Biol
, vol.137
, pp. 17-28
-
-
Silverman, J.A.1
Mindell, J.A.2
Zhan, H.3
Finkelstein, A.4
Collier, R.J.5
-
95
-
-
0028297567
-
Structure-function relationships in diphtheria toxin channels: III. Residues which affect the cis pH dependence of channel conductance
-
Mindell JA, Silverman JA, Collier RJ, Finkelstein A Structure-function relationships in diphtheria toxin channels: III. Residues which affect the cis pH dependence of channel conductance. J Membr Biol 1994, 137:45-57.
-
(1994)
J Membr Biol
, vol.137
, pp. 45-57
-
-
Mindell, J.A.1
Silverman, J.A.2
Collier, R.J.3
Finkelstein, A.4
-
96
-
-
0028221680
-
Structure function relationships in diphtheria toxin channels: II. A residue responsible for the channel's dependence on trans pH
-
Mindell JA, Silverman JA, Collier RJ, Finkelstein A Structure function relationships in diphtheria toxin channels: II. A residue responsible for the channel's dependence on trans pH. J Membr Biol 1994, 137:29-44.
-
(1994)
J Membr Biol
, vol.137
, pp. 29-44
-
-
Mindell, J.A.1
Silverman, J.A.2
Collier, R.J.3
Finkelstein, A.4
-
97
-
-
0030900233
-
Structure-function relationship of the ion channel formed by diphtheria toxin in vero cell membranes
-
Lanzrein M, Falnes PO, Sand O, Olsnes S Structure-function relationship of the ion channel formed by diphtheria toxin in vero cell membranes. J Membr Biol 1997, 156:141-148.
-
(1997)
J Membr Biol
, vol.156
, pp. 141-148
-
-
Lanzrein, M.1
Falnes, P.O.2
Sand, O.3
Olsnes, S.4
-
98
-
-
0024115012
-
On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells
-
Papini E, Sandona D, Rappuoli R, Montecucco C On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells. Embo J 1988, 7:3353-3359.
-
(1988)
Embo J
, vol.7
, pp. 3353-3359
-
-
Papini, E.1
Sandona, D.2
Rappuoli, R.3
Montecucco, C.4
-
99
-
-
0033215457
-
Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization
-
Sharpe JC, London E Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization. J Membr Biol 1999, 171:209-221.
-
(1999)
J Membr Biol
, vol.171
, pp. 209-221
-
-
Sharpe, J.C.1
London, E.2
-
100
-
-
0036453185
-
Structure and function of diphtheria toxin: from pathology to engineering
-
Chenal A, Nizard P, Gillet D Structure and function of diphtheria toxin: from pathology to engineering. J. Toxicol.-Tox. Rev 2002, 21:321-359.
-
(2002)
J. Toxicol.-Tox. Rev
, vol.21
, pp. 321-359
-
-
Chenal, A.1
Nizard, P.2
Gillet, D.3
-
101
-
-
84881596511
-
Ph-triggered conformational switching along the membrane insertion pathway of the diphtheria toxin T-domain
-
Ladokhin AS Ph-triggered conformational switching along the membrane insertion pathway of the diphtheria toxin T-domain. Toxins (Basel) 2013, 5:1362-1380.
-
(2013)
Toxins (Basel)
, vol.5
, pp. 1362-1380
-
-
Ladokhin, A.S.1
-
102
-
-
0027443116
-
Rendering a membrane protein soluble in water: a common packing motif in bacterial protein toxins
-
Parker MW, Pattus F Rendering a membrane protein soluble in water: a common packing motif in bacterial protein toxins. Trends Biochem Sci 1993, 18:391-395.
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 391-395
-
-
Parker, M.W.1
Pattus, F.2
-
103
-
-
33847018480
-
Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction
-
Montagner C, Perier A, Pichard S, Vernier G, Menez A, Gillet D, et al. Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction. Biochemistry 2007, 46:1878-1887.
-
(2007)
Biochemistry
, vol.46
, pp. 1878-1887
-
-
Montagner, C.1
Perier, A.2
Pichard, S.3
Vernier, G.4
Menez, A.5
Gillet, D.6
-
104
-
-
0036271438
-
Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain
-
Chenal A, Nizard P, Forge V, Pugniere M, Roy MO, Mani JC, et al. Does fusion of domains from unrelated proteins affect their folding pathways and the structural changes involved in their function? A case study with the diphtheria toxin T domain. Protein Eng 2002, 15:383-391.
-
(2002)
Protein Eng
, vol.15
, pp. 383-391
-
-
Chenal, A.1
Nizard, P.2
Forge, V.3
Pugniere, M.4
Roy, M.O.5
Mani, J.C.6
-
105
-
-
0028144832
-
Dynamic transitions of the transmembrane domain of diphtheria toxin: disulfide trapping and fluorescence proximity studies
-
Zhan H, Choe S, Huynh PD, Finkelstein A, Eisenberg D, Collier RJ Dynamic transitions of the transmembrane domain of diphtheria toxin: disulfide trapping and fluorescence proximity studies. Biochemistry 1994, 33:11254-11263.
-
(1994)
Biochemistry
, vol.33
, pp. 11254-11263
-
-
Zhan, H.1
Choe, S.2
Huynh, P.D.3
Finkelstein, A.4
Eisenberg, D.5
Collier, R.J.6
-
106
-
-
75149142227
-
Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen/deuterium exchange measurements
-
Man P, Montagner C, Vitrac H, Kavan D, Pichard S, Gillet D, et al. Accessibility changes within diphtheria toxin T domain when in the functional molten globule state, as determined using hydrogen/deuterium exchange measurements. FEBS J 2010, 277:653-662.
-
(2010)
FEBS J
, vol.277
, pp. 653-662
-
-
Man, P.1
Montagner, C.2
Vitrac, H.3
Kavan, D.4
Pichard, S.5
Gillet, D.6
-
107
-
-
0002940127
-
The molten globule state
-
Freeman, New York, T.E. Creighton (Ed.)
-
Ptitsyn OB The molten globule state. Protein folding 1992, 243-300. Freeman, New York. T.E. Creighton (Ed.).
-
(1992)
Protein folding
, pp. 243-300
-
-
Ptitsyn, O.B.1
-
108
-
-
0030059690
-
The molten globule state of alpha-lactalbumin
-
Kuwajima K The molten globule state of alpha-lactalbumin. Faseb J 1996, 10:102-109.
-
(1996)
Faseb J
, vol.10
, pp. 102-109
-
-
Kuwajima, K.1
-
109
-
-
0030803672
-
Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width
-
Wang Y, Malenbaum SE, Kachel K, Zhan H, Collier RJ, London E Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width. J Biol Chem 1997, 272:25091-25098.
-
(1997)
J Biol Chem
, vol.272
, pp. 25091-25098
-
-
Wang, Y.1
Malenbaum, S.E.2
Kachel, K.3
Zhan, H.4
Collier, R.J.5
London, E.6
-
110
-
-
0032558976
-
Membrane topography of the T domain of diphtheria toxin probed with single tryptophan mutants
-
Malenbaum SE, Collier RJ, London E Membrane topography of the T domain of diphtheria toxin probed with single tryptophan mutants. Biochemistry 1998, 37:17915-17922.
-
(1998)
Biochemistry
, vol.37
, pp. 17915-17922
-
-
Malenbaum, S.E.1
Collier, R.J.2
London, E.3
-
111
-
-
44849136504
-
Interactions of fluorinated surfactants with diphtheria toxin t-domain: testing new media for studies of membrane proteins
-
Rodnin MV, Posokhov YO, Contino-Pepin C, Brettmann J, Kyrychenko A, Palchevskyy SS, et al. Interactions of fluorinated surfactants with diphtheria toxin t-domain: testing new media for studies of membrane proteins. Biophys J 2008, 94:4348-4357.
-
(2008)
Biophys J
, vol.94
, pp. 4348-4357
-
-
Rodnin, M.V.1
Posokhov, Y.O.2
Contino-Pepin, C.3
Brettmann, J.4
Kyrychenko, A.5
Palchevskyy, S.S.6
-
112
-
-
34548283134
-
Concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin t domain
-
Perier A, Chassaing A, Raffestin S, Pichard S, Masella M, Menez A, et al. Concerted protonation of key histidines triggers membrane interaction of the diphtheria toxin t domain. J Biol Chem 2007, 282:24239-24245.
-
(2007)
J Biol Chem
, vol.282
, pp. 24239-24245
-
-
Perier, A.1
Chassaing, A.2
Raffestin, S.3
Pichard, S.4
Masella, M.5
Menez, A.6
-
113
-
-
77956172558
-
Conformational switching of the diphtheria toxin T domain
-
Rodnin MV, Kyrychenko A, Kienker P, Sharma O, Posokhov YO, Collier RJ, et al. Conformational switching of the diphtheria toxin T domain. J Mol Biol 2010, 402:1-7.
-
(2010)
J Mol Biol
, vol.402
, pp. 1-7
-
-
Rodnin, M.V.1
Kyrychenko, A.2
Kienker, P.3
Sharma, O.4
Posokhov, Y.O.5
Collier, R.J.6
-
114
-
-
84879946745
-
Ph-triggered conformational switching of the diphtheria toxin t-domain: the roles of n-terminal histidines
-
Kurnikov IV, Kyrychenko A, Flores-Canales JC, Rodnin MV, Simakov N, Vargas-Uribe M, et al. Ph-triggered conformational switching of the diphtheria toxin t-domain: the roles of n-terminal histidines. J Mol Biol 2013, 425:2752-2764.
-
(2013)
J Mol Biol
, vol.425
, pp. 2752-2764
-
-
Kurnikov, I.V.1
Kyrychenko, A.2
Flores-Canales, J.C.3
Rodnin, M.V.4
Simakov, N.5
Vargas-Uribe, M.6
-
115
-
-
81255184305
-
Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain
-
Rodnin MV, Kyrychenko A, Kienker P, Sharma O, Vargas-Uribe M, Collier RJ, et al. Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain. Biophys J 2011, 101:L41-L43.
-
(2011)
Biophys J
, vol.101
, pp. L41-L43
-
-
Rodnin, M.V.1
Kyrychenko, A.2
Kienker, P.3
Sharma, O.4
Vargas-Uribe, M.5
Collier, R.J.6
-
116
-
-
84878229869
-
Crucial role of H322 in folding of the diphtheria toxin t-domain into the open-channel state
-
Vargas-Uribe M, Rodnin MV, Kienker P, Finkelstein A, Ladokhin AS Crucial role of H322 in folding of the diphtheria toxin t-domain into the open-channel state. Biochemistry 2013, 52:3457-3463.
-
(2013)
Biochemistry
, vol.52
, pp. 3457-3463
-
-
Vargas-Uribe, M.1
Rodnin, M.V.2
Kienker, P.3
Finkelstein, A.4
Ladokhin, A.S.5
-
117
-
-
0032483451
-
Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain
-
Kachel K, Ren J, Collier RJ, London E Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain. J Biol Chem 1998, 273:22950-22956.
-
(1998)
J Biol Chem
, vol.273
, pp. 22950-22956
-
-
Kachel, K.1
Ren, J.2
Collier, R.J.3
London, E.4
-
118
-
-
68449095990
-
Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy
-
Chenal A, Prongidi-Fix L, Perier A, Aisenbrey C, Vernier G, Lambotte S, et al. Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy. J Mol Biol 2009, 391:872-883.
-
(2009)
J Mol Biol
, vol.391
, pp. 872-883
-
-
Chenal, A.1
Prongidi-Fix, L.2
Perier, A.3
Aisenbrey, C.4
Vernier, G.5
Lambotte, S.6
-
119
-
-
81055156662
-
Accessibility changes within diphtheria toxin T domain upon membrane penetration probed by hydrogen exchange and mass spectrometry
-
Man P, Montagner C, Vitrac H, Kavan D, Pichard S, Gillet D, et al. Accessibility changes within diphtheria toxin T domain upon membrane penetration probed by hydrogen exchange and mass spectrometry. J Mol Biol 2011, 414:123-134.
-
(2011)
J Mol Biol
, vol.414
, pp. 123-134
-
-
Man, P.1
Montagner, C.2
Vitrac, H.3
Kavan, D.4
Pichard, S.5
Gillet, D.6
-
120
-
-
69949119628
-
Side chain resonances in static oriented proton-decoupled 15n solid-state nmr spectra of membrane proteins
-
Aisenbrey C, Prongidi-Fix L, Chenal A, Gillet D, Bechinger B Side chain resonances in static oriented proton-decoupled 15n solid-state nmr spectra of membrane proteins. J Am Chem Soc 2009, 131:6340-6341.
-
(2009)
J Am Chem Soc
, vol.131
, pp. 6340-6341
-
-
Aisenbrey, C.1
Prongidi-Fix, L.2
Chenal, A.3
Gillet, D.4
Bechinger, B.5
-
121
-
-
0028908353
-
Interaction of the isolated transmembrane domain of diphtheria toxin with membranes
-
Zhan H, Oh KJ, Shin YK, Hubbell WL, Collier RJ Interaction of the isolated transmembrane domain of diphtheria toxin with membranes. Biochemistry 1995, 34:4856-4863.
-
(1995)
Biochemistry
, vol.34
, pp. 4856-4863
-
-
Zhan, H.1
Oh, K.J.2
Shin, Y.K.3
Hubbell, W.L.4
Collier, R.J.5
-
122
-
-
0000704357
-
Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop
-
Oh KJ, Zhan H, Cui C, Altenbach C, Hubbell WL, Collier RJ Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop. Biochemistry 1999, 38:10336-10343.
-
(1999)
Biochemistry
, vol.38
, pp. 10336-10343
-
-
Oh, K.J.1
Zhan, H.2
Cui, C.3
Altenbach, C.4
Hubbell, W.L.5
Collier, R.J.6
-
123
-
-
0001350946
-
Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study
-
Oh KJ, Zhan H, Cui C, Hideg K, Collier RJ, Hubbell WL Organization of diphtheria toxin T domain in bilayers: a site-directed spin labeling study. Science 1996, 273:810-812.
-
(1996)
Science
, vol.273
, pp. 810-812
-
-
Oh, K.J.1
Zhan, H.2
Cui, C.3
Hideg, K.4
Collier, R.J.5
Hubbell, W.L.6
-
124
-
-
0027989890
-
Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain
-
Silverman JA, Mindell JA, Finkelstein A, Shen WH, Collier RJ Mutational analysis of the helical hairpin region of diphtheria toxin transmembrane domain. J Biol Chem 1994, 269:22524-22532.
-
(1994)
J Biol Chem
, vol.269
, pp. 22524-22532
-
-
Silverman, J.A.1
Mindell, J.A.2
Finkelstein, A.3
Shen, W.H.4
Collier, R.J.5
-
125
-
-
0026643615
-
Locating a residue in the diphtheria toxin channel
-
Mindell JA, Silverman JA, Collier RJ, Finkelstein A Locating a residue in the diphtheria toxin channel. Biophys J 1992, 62:41-44.
-
(1992)
Biophys J
, vol.62
, pp. 41-44
-
-
Mindell, J.A.1
Silverman, J.A.2
Collier, R.J.3
Finkelstein, A.4
-
126
-
-
0034081629
-
Topography of diphtheria toxin's t domain in the open channel state
-
Senzel L, Gordon M, Blaustein RO, Oh KJ, Collier RJ, Finkelstein A Topography of diphtheria toxin's t domain in the open channel state. J Gen Physiol 2000, 115:421-434.
-
(2000)
J Gen Physiol
, vol.115
, pp. 421-434
-
-
Senzel, L.1
Gordon, M.2
Blaustein, R.O.3
Oh, K.J.4
Collier, R.J.5
Finkelstein, A.6
-
127
-
-
0029814353
-
Topology of diphtheria toxin in lipid vesicle membranes: a proteolysis study
-
Quertenmont P, Wattiez R, Falmagne P, Ruysschaert JM, Cabiaux V Topology of diphtheria toxin in lipid vesicle membranes: a proteolysis study. Mol Microbiol 1996, 21:1283-1296.
-
(1996)
Mol Microbiol
, vol.21
, pp. 1283-1296
-
-
Quertenmont, P.1
Wattiez, R.2
Falmagne, P.3
Ruysschaert, J.M.4
Cabiaux, V.5
-
128
-
-
0028276245
-
Topology of diphtheria toxin B fragment inserted in lipid vesicles
-
Cabiaux V, Quertenmont P, Conrath K, Brasseur R, Capiau C, Ruysschaert JM Topology of diphtheria toxin B fragment inserted in lipid vesicles. Mol Microbiol 1994, 11:43-50.
-
(1994)
Mol Microbiol
, vol.11
, pp. 43-50
-
-
Cabiaux, V.1
Quertenmont, P.2
Conrath, K.3
Brasseur, R.4
Capiau, C.5
Ruysschaert, J.M.6
-
129
-
-
0034697302
-
Organization of diphtheria toxin in membranes. A hydrophobic photolabeling study
-
D'Silva PR, Lala AK Organization of diphtheria toxin in membranes. A hydrophobic photolabeling study. J Biol Chem 2000, 275:11771-11777.
-
(2000)
J Biol Chem
, vol.275
, pp. 11771-11777
-
-
D'Silva, P.R.1
Lala, A.K.2
-
130
-
-
27344460405
-
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol
-
Ratts R, Trujillo C, Bharti A, vanderSpek J, Harrison R, Murphy JR A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol. Proc Natl Acad Sci USA 2005, 102:15635-15640.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15635-15640
-
-
Ratts, R.1
Trujillo, C.2
Bharti, A.3
vanderSpek, J.4
Harrison, R.5
Murphy, J.R.6
-
131
-
-
0031415407
-
Use of TRP mutations to evaluate the conformational behavior and membrane insertion of A and B chains in whole diphtheria toxin
-
Wang Y, Kachel K, Pablo L, London E Use of TRP mutations to evaluate the conformational behavior and membrane insertion of A and B chains in whole diphtheria toxin. Biochemistry 1997, 36:16300-16308.
-
(1997)
Biochemistry
, vol.36
, pp. 16300-16308
-
-
Wang, Y.1
Kachel, K.2
Pablo, L.3
London, E.4
-
132
-
-
0033532355
-
Interaction of diphtheria toxin T domain with molten globule-like proteins and its implications for translocation
-
Ren J, Kachel K, Kim H, Malenbaum SE, Collier RJ, London E Interaction of diphtheria toxin T domain with molten globule-like proteins and its implications for translocation. Science 1999, 284:955-957.
-
(1999)
Science
, vol.284
, pp. 955-957
-
-
Ren, J.1
Kachel, K.2
Kim, H.3
Malenbaum, S.E.4
Collier, R.J.5
London, E.6
-
133
-
-
0026927004
-
Ion channel and membrane translocation of diphtheria toxin
-
Montecucco C, Papini E, Schiavo G, Padovan E, Rossetto O Ion channel and membrane translocation of diphtheria toxin. FEMS Microbiol Immunol 1992, 5:101-111.
-
(1992)
FEMS Microbiol Immunol
, vol.5
, pp. 101-111
-
-
Montecucco, C.1
Papini, E.2
Schiavo, G.3
Padovan, E.4
Rossetto, O.5
-
134
-
-
0000483941
-
Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain
-
Oh KJ, Senzel L, Collier RJ, Finkelstein A Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain. Proc Natl Acad Sci USA 1999, 96:8467-8470.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8467-8470
-
-
Oh, K.J.1
Senzel, L.2
Collier, R.J.3
Finkelstein, A.4
-
135
-
-
0029383734
-
Targeting diphtheria toxin to growth factor receptors
-
Murphy JR, vanderSpek JC Targeting diphtheria toxin to growth factor receptors. Semin Cancer Biol 1995, 6:259-267.
-
(1995)
Semin Cancer Biol
, vol.6
, pp. 259-267
-
-
Murphy, J.R.1
vanderSpek, J.C.2
-
136
-
-
0031719786
-
The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2
-
Hu HY, Huynh PD, Murphy JR, vanderSpek JC The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2. Protein Eng 1998, 11:811-817.
-
(1998)
Protein Eng
, vol.11
, pp. 811-817
-
-
Hu, H.Y.1
Huynh, P.D.2
Murphy, J.R.3
vanderSpek, J.C.4
-
137
-
-
0027241029
-
Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells
-
vanderSpek JC, Mindell JA, Finkelstein A, Murphy JR Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells. J Biol Chem 1993, 268:12077-12082.
-
(1993)
J Biol Chem
, vol.268
, pp. 12077-12082
-
-
vanderSpek, J.C.1
Mindell, J.A.2
Finkelstein, A.3
Murphy, J.R.4
-
138
-
-
0028025127
-
Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells
-
vanderSpek JC, Howland K, Friedman T, Murphy JR Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells. Protein Eng 1994, 7:985-989.
-
(1994)
Protein Eng
, vol.7
, pp. 985-989
-
-
vanderSpek, J.C.1
Howland, K.2
Friedman, T.3
Murphy, J.R.4
-
139
-
-
0028022018
-
An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells
-
vanderSpek J, Cassidy D, Genbauffe F, Huynh PD, Murphy JR An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells. J Biol Chem 1994, 269:21455-21459.
-
(1994)
J Biol Chem
, vol.269
, pp. 21455-21459
-
-
vanderSpek, J.1
Cassidy, D.2
Genbauffe, F.3
Huynh, P.D.4
Murphy, J.R.5
-
140
-
-
0028292770
-
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
-
Falnes PO, Choe S, Madshus IH, Wilson BA, Olsnes S Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges. J Biol Chem 1994, 269:8402-8407.
-
(1994)
J Biol Chem
, vol.269
, pp. 8402-8407
-
-
Falnes, P.O.1
Choe, S.2
Madshus, I.H.3
Wilson, B.A.4
Olsnes, S.5
-
141
-
-
0033922714
-
Penetration of protein toxins into cells
-
Falnes PO, Sandvig K Penetration of protein toxins into cells. Curr Opin Cell Biol 2000, 12:407-413.
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 407-413
-
-
Falnes, P.O.1
Sandvig, K.2
-
142
-
-
0023696942
-
Conformation and model membrane interactions of diphtheria toxin fragment A
-
Zhao JM, London E Conformation and model membrane interactions of diphtheria toxin fragment A. J Biol Chem 1988, 263:15369-15377.
-
(1988)
J Biol Chem
, vol.263
, pp. 15369-15377
-
-
Zhao, J.M.1
London, E.2
-
143
-
-
0028328846
-
Dual mode of signal transduction by externally added acidic fibroblast growth factor
-
Wiedlocha A, Falnes PO, Madshus IH, Sandvig K, Olsnes S Dual mode of signal transduction by externally added acidic fibroblast growth factor. Cell 1994, 76:1039-1051.
-
(1994)
Cell
, vol.76
, pp. 1039-1051
-
-
Wiedlocha, A.1
Falnes, P.O.2
Madshus, I.H.3
Sandvig, K.4
Olsnes, S.5
-
144
-
-
0030044491
-
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
-
Klingenberg O, Olsnes S Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin. Biochem J 1996, 313:647-653.
-
(1996)
Biochem J
, vol.313
, pp. 647-653
-
-
Klingenberg, O.1
Olsnes, S.2
-
145
-
-
0028180162
-
The N-terminal alpha-helix of fragment B of diphtheria toxin promotes translocation of fragment A into the cytoplasm of eukaryotic cells
-
Madshus IH The N-terminal alpha-helix of fragment B of diphtheria toxin promotes translocation of fragment A into the cytoplasm of eukaryotic cells. J Biol Chem 1994, 269:17723-17729.
-
(1994)
J Biol Chem
, vol.269
, pp. 17723-17729
-
-
Madshus, I.H.1
-
146
-
-
0031714548
-
The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers
-
Senzel L, Huynh PD, Jakes KS, Collier RJ, Finkelstein A The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers. J Gen Physiol 1998, 112:317-324.
-
(1998)
J Gen Physiol
, vol.112
, pp. 317-324
-
-
Senzel, L.1
Huynh, P.D.2
Jakes, K.S.3
Collier, R.J.4
Finkelstein, A.5
-
147
-
-
0028001091
-
Intermediates in translocation of diphtheria toxin across the plasma membrane
-
Madshus IH, Wiedlocha A, Sandvig K Intermediates in translocation of diphtheria toxin across the plasma membrane. J Biol Chem 1994, 269:4648-4652.
-
(1994)
J Biol Chem
, vol.269
, pp. 4648-4652
-
-
Madshus, I.H.1
Wiedlocha, A.2
Sandvig, K.3
-
148
-
-
0032478734
-
Diphtheria toxin translocation across endosome membranes. A novel cell permeabilization assay reveals new diphtheria toxin fragments in endocytic vesicles
-
Umata T, Mekada E Diphtheria toxin translocation across endosome membranes. A novel cell permeabilization assay reveals new diphtheria toxin fragments in endocytic vesicles. J Biol Chem 1998, 273:8351-8359.
-
(1998)
J Biol Chem
, vol.273
, pp. 8351-8359
-
-
Umata, T.1
Mekada, E.2
-
149
-
-
0015984005
-
Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide
-
Kandel J, Collier RJ, Chung DW Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide. J Biol Chem 1974, 249:2088-2097.
-
(1974)
J Biol Chem
, vol.249
, pp. 2088-2097
-
-
Kandel, J.1
Collier, R.J.2
Chung, D.W.3
-
150
-
-
0021876906
-
Primary structure of elongation factor 2 around the site of ADP-ribosylation is highly conserved from archaebacteria to eukaryotes
-
Gehrmann R, Henschen A, Klink F Primary structure of elongation factor 2 around the site of ADP-ribosylation is highly conserved from archaebacteria to eukaryotes. FEBS Lett 1985, 185:37-42.
-
(1985)
FEBS Lett
, vol.185
, pp. 37-42
-
-
Gehrmann, R.1
Henschen, A.2
Klink, F.3
-
151
-
-
0027529133
-
Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin
-
Phan LD, Perentesis JP, Bodley JW Saccharomyces cerevisiae elongation factor 2. Mutagenesis of the histidine precursor of diphthamide yields a functional protein that is resistant to diphtheria toxin. J Biol Chem 1993, 268:8665-8668.
-
(1993)
J Biol Chem
, vol.268
, pp. 8665-8668
-
-
Phan, L.D.1
Perentesis, J.P.2
Bodley, J.W.3
-
152
-
-
0028241366
-
Elongation factor 2 mutants deficient in diphthamide formation show temperature-sensitive cell growth
-
Kimata Y, Kohno K Elongation factor 2 mutants deficient in diphthamide formation show temperature-sensitive cell growth. J Biol Chem 1994, 269:13497-13501.
-
(1994)
J Biol Chem
, vol.269
, pp. 13497-13501
-
-
Kimata, Y.1
Kohno, K.2
-
153
-
-
0028150748
-
Cellular ADP-ribosylation of elongation factor 2
-
Iglewski WJ Cellular ADP-ribosylation of elongation factor 2. Mol Cell Biochem 1994, 138:131-133.
-
(1994)
Mol Cell Biochem
, vol.138
, pp. 131-133
-
-
Iglewski, W.J.1
-
154
-
-
0024495952
-
Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells
-
Fendrick JL, Iglewski WJ Endogenous ADP-ribosylation of elongation factor 2 in polyoma virus-transformed baby hamster kidney cells. Proc Natl Acad Sci USA 1989, 86:554-557.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 554-557
-
-
Fendrick, J.L.1
Iglewski, W.J.2
-
155
-
-
78650819063
-
A dominant-negative approach that prevents diphthamide formation confers resistance to pseudomonas exotoxin A and diphtheria toxin
-
Roy V, Ghani K, Caruso M A dominant-negative approach that prevents diphthamide formation confers resistance to pseudomonas exotoxin A and diphtheria toxin. PLoS ONE 2010, 5:e15753.
-
(2010)
PLoS ONE
, vol.5
, pp. e15753
-
-
Roy, V.1
Ghani, K.2
Caruso, M.3
-
156
-
-
0024364955
-
Histidine 21 is at the NAD+binding site of diphtheria toxin
-
Papini E, Schiavo G, Sandona D, Rappuoli R, Montecucco C Histidine 21 is at the NAD+binding site of diphtheria toxin. J Biol Chem 1989, 264:12385-12388.
-
(1989)
J Biol Chem
, vol.264
, pp. 12385-12388
-
-
Papini, E.1
Schiavo, G.2
Sandona, D.3
Rappuoli, R.4
Montecucco, C.5
-
157
-
-
0028260470
-
Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2
-
Blanke SR, Huang K, Wilson BA, Papini E, Covacci A, Collier RJ Active-site mutations of the diphtheria toxin catalytic domain: role of histidine-21 in nicotinamide adenine dinucleotide binding and ADP-ribosylation of elongation factor 2. Biochemistry 1994, 33:5155-5161.
-
(1994)
Biochemistry
, vol.33
, pp. 5155-5161
-
-
Blanke, S.R.1
Huang, K.2
Wilson, B.A.3
Papini, E.4
Covacci, A.5
Collier, R.J.6
-
158
-
-
0027939547
-
Histidine 21 does not play a major role in diphtheria toxin catalysis
-
Johnson VG, Nicholls PJ Histidine 21 does not play a major role in diphtheria toxin catalysis. J Biol Chem 1994, 269:4349-4354.
-
(1994)
J Biol Chem
, vol.269
, pp. 4349-4354
-
-
Johnson, V.G.1
Nicholls, P.J.2
-
159
-
-
0025835440
-
Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin
-
Papini E, Santucci A, Schiavo G, Domenighini M, Neri P, Rappuoli R, et al. Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin. J Biol Chem 1991, 266:2494-2498.
-
(1991)
J Biol Chem
, vol.266
, pp. 2494-2498
-
-
Papini, E.1
Santucci, A.2
Schiavo, G.3
Domenighini, M.4
Neri, P.5
Rappuoli, R.6
-
160
-
-
0028574376
-
Active-site mutations of diphtheria toxin: role of tyrosine-65 in nad binding and adp-ribosylation
-
Blanke SR, Huang K, Collier RJ Active-site mutations of diphtheria toxin: role of tyrosine-65 in nad binding and adp-ribosylation. Biochemistry 1994, 33:15494-15500.
-
(1994)
Biochemistry
, vol.33
, pp. 15494-15500
-
-
Blanke, S.R.1
Huang, K.2
Collier, R.J.3
-
161
-
-
0021280847
-
NAD-binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD
-
Carroll SF, Collier RJ NAD-binding site of diphtheria toxin: identification of a residue within the nicotinamide subsite by photochemical modification with NAD. Proc Natl Acad Sci USA 1984, 81:3307-3311.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 3307-3311
-
-
Carroll, S.F.1
Collier, R.J.2
-
162
-
-
0022367923
-
Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148
-
Carroll SF, McCloskey JA, Crain PF, Oppenheimer NJ, Marschner TM, Collier RJ Photoaffinity labeling of diphtheria toxin fragment A with NAD: structure of the photoproduct at position 148. Proc Natl Acad Sci USA 1985, 82:7237-7241.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 7237-7241
-
-
Carroll, S.F.1
McCloskey, J.A.2
Crain, P.F.3
Oppenheimer, N.J.4
Marschner, T.M.5
Collier, R.J.6
-
163
-
-
0017725370
-
The mechanism of ADP-ribosylation of elongation factor 2 catalyzed by fragment A from diphtheria toxin
-
Chung DW, Collier RJ The mechanism of ADP-ribosylation of elongation factor 2 catalyzed by fragment A from diphtheria toxin. Biochim Biophys Acta 1977, 483:248-257.
-
(1977)
Biochim Biophys Acta
, vol.483
, pp. 248-257
-
-
Chung, D.W.1
Collier, R.J.2
-
164
-
-
0026609066
-
Diphtheria toxin and pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism
-
Wilson BA, Collier RJ Diphtheria toxin and pseudomonas aeruginosa exotoxin A: active-site structure and enzymic mechanism. Curr Top Microbiol Immunol 1992, 175:27-41.
-
(1992)
Curr Top Microbiol Immunol
, vol.175
, pp. 27-41
-
-
Wilson, B.A.1
Collier, R.J.2
-
165
-
-
0034280315
-
DAB(389)IL-2 (Ontak): a novel fusion toxin therapy for lymphoma
-
[discussion 117]
-
Foss FM DAB(389)IL-2 (Ontak): a novel fusion toxin therapy for lymphoma. Clin Lymphoma 2000, 1:110-116. [discussion 117].
-
(2000)
Clin Lymphoma
, vol.1
, pp. 110-116
-
-
Foss, F.M.1
|