Conformational Switching of the Diphtheria Toxin T Domain

Journal of Molecular Biology

Volumn 402, Issue 1, 2010, Pages 1-7

  Rodnin, Mykola V ^a   Kyrychenko, Alexander ^a   Kienker, Paul ^b   Sharma, Onkar ^c   Posokhov, Yevgen O ^a   Collier, R John ^c   Finkelstein, Alan ^b   Ladokhin, Alexey S ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Conformational switch; Histidine protonation; Lipid bilayer insertion; Membrane protein folding; Tryptophan fluorescence

Indexed keywords

ARGININE; DIPHTHERIA TOXIN; DIPHTHERIA TOXIN T DOMAIN; GLUTAMINE; HISTIDINE; UNCLASSIFIED DRUG; LIPID BILAYER; PROTON;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL ASSAY; CHANNEL GATING; CONFORMATIONAL SWITCHING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; LIPID MEMBRANE; MEMBRANE PERMEABILITY; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; WILD TYPE; CELL MEMBRANE; CHEMISTRY; GENETICS; LIPID BILAYER; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SUBSTITUTION; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DIPHTHERIA TOXIN; HISTIDINE; HYDROGEN-ION CONCENTRATION; LIPID BILAYERS; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTONS;

EID: 77956172558     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.07.024     Document Type: Article

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