The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2

Protein Engineering

Volumn 11, Issue 9, 1998, Pages 811-817

  Hu, Hong Yu ^a,b   Huynh, Paul D ^c   Murphy, John R ^a   VanderSpek, Johanna C ^a  

^a BOSTON MEDICAL CENTER   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Diphtheria toxin; Fusion toxin; Transmembrane domain

Indexed keywords

DIPHTHERIA TOXIN; HYBRID PROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MEMBRANE PROTEIN; MUTANT PROTEIN; PROLINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CHANNEL GATING; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; EUKARYOTIC CELL; HUMAN; HUMAN CELL; LIPID BILAYER; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; TOXIN STRUCTURE;

EUKARYOTA;

EID: 0031719786     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.9.811     Document Type: Article

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