메뉴 건너뛰기




Volumn 29, Issue 5, 1998, Pages 1275-1284

Toxin binding site of the diphtheria toxin receptor: Loss and gain of diphtheria toxin binding of monkey and mouse heparin-binding, epidermal growth factor-like growth factor precursors by reciprocal site-directed mutagenesis

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL TOXIN; EPIDERMAL GROWTH FACTOR; HEPARIN BINDING PROTEIN;

EID: 0031683636     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.01015.x     Document Type: Article
Times cited : (28)

References (31)
  • 1
    • 0027203216 scopus 로고
    • Heparin-binding EGF-like growth factor: Characterization of rat and mouse cDNA clones, protein domain conservation across species, and transcript expression in tissues
    • Abraham, J.A., Damm, D., Bajardi, A., Miller, J., Klagsbrun, M., and Ezekowitz, R.A. (1993) Heparin-binding EGF-like growth factor: characterization of rat and mouse cDNA clones, protein domain conservation across species, and transcript expression in tissues. Biochem Biophys Res Commun 190: 125-133.
    • (1993) Biochem Biophys Res Commun , vol.190 , pp. 125-133
    • Abraham, J.A.1    Damm, D.2    Bajardi, A.3    Miller, J.4    Klagsbrun, M.5    Ezekowitz, R.A.6
  • 2
    • 0028171066 scopus 로고
    • The cytoplasmic domain of the diphtheria toxin receptor (HB-EGF precursor) is not required for receptor-mediated endocytosis
    • Almond, B.D., and Eidels, L. (1994) The cytoplasmic domain of the diphtheria toxin receptor (HB-EGF precursor) is not required for receptor-mediated endocytosis. J Biol Chem 269: 26635-26641.
    • (1994) J Biol Chem , vol.269 , pp. 26635-26641
    • Almond, B.D.1    Eidels, L.2
  • 3
    • 0027992745 scopus 로고
    • An optimized electroporation protocol applicable to a wide range of cell lines
    • Baum, C., Forster, P., Hegewisch-Becker, S., and Harbers, K. (1994) An optimized electroporation protocol applicable to a wide range of cell lines. BioTechniques 17: 1058-1062.
    • (1994) BioTechniques , vol.17 , pp. 1058-1062
    • Baum, C.1    Forster, P.2    Hegewisch-Becker, S.3    Harbers, K.4
  • 4
    • 0027169924 scopus 로고
    • Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen
    • Brown, J.G., Almond, B.D., Naglich, J.G., and Eidels, L. (1993) Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen. Proc Natl Acad Sci USA 90: 8184-8188.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8184-8188
    • Brown, J.G.1    Almond, B.D.2    Naglich, J.G.3    Eidels, L.4
  • 5
    • 0001916717 scopus 로고
    • The epidermal growth factor family
    • Sporn, M.B., and Roberts, A.B. (eds). New York: Springer-Verlag
    • Carpenter, G., and Wahl, M.I. (1990) The epidermal growth factor family. In Handbook of Experimental Pharmacology, Vol. 95. Sporn, M.B., and Roberts, A.B. (eds). New York: Springer-Verlag, pp. 69-171.
    • (1990) Handbook of Experimental Pharmacology , vol.95 , pp. 69-171
    • Carpenter, G.1    Wahl, M.I.2
  • 6
    • 0023664984 scopus 로고
    • Diphtheria toxin receptor. Identification of specific diphtheria toxin-binding proteins on the surface of Vero and BS-C-1 cells
    • Cieplak, W., Gaudin, H.M., and Eidels, L. (1987) Diphtheria toxin receptor. Identification of specific diphtheria toxin-binding proteins on the surface of Vero and BS-C-1 cells. J Biol Chem 262: 13246-13253.
    • (1987) J Biol Chem , vol.262 , pp. 13246-13253
    • Cieplak, W.1    Gaudin, H.M.2    Eidels, L.3
  • 7
    • 0016609883 scopus 로고
    • Diphtheria toxin: Mode of action and structure
    • Collier, R.J. (1975) Diphtheria toxin: mode of action and structure. Bacteriol Rev 39: 54-85.
    • (1975) Bacteriol Rev , vol.39 , pp. 54-85
    • Collier, R.J.1
  • 8
    • 0018638142 scopus 로고
    • Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells
    • Dorland, R.B., Middlebrook, J.L., and Leppla, S.H. (1979) Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells. J Biol Chem 254: 11337-11342.
    • (1979) J Biol Chem , vol.254 , pp. 11337-11342
    • Dorland, R.B.1    Middlebrook, J.L.2    Leppla, S.H.3
  • 9
    • 0019989761 scopus 로고
    • Effect of polymers of L-lysine on the cytotoxic action of diphtheria toxin
    • Eidels, L., and Hart, D.A. (1982) Effect of polymers of L-lysine on the cytotoxic action of diphtheria toxin. Infect Immun 37: 1054-1058.
    • (1982) Infect Immun , vol.37 , pp. 1054-1058
    • Eidels, L.1    Hart, D.A.2
  • 10
    • 0021015433 scopus 로고
    • Membrane receptors for bacterial toxins
    • Eidels, L., Proia, R.L., and Hart, D.A. (1983) Membrane receptors for bacterial toxins. Microbiol Rev 47: 596-620.
    • (1983) Microbiol Rev , vol.47 , pp. 596-620
    • Eidels, L.1    Proia, R.L.2    Hart, D.A.3
  • 11
    • 0029118420 scopus 로고
    • Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: Conversion from juxtacrine to paracrine growth factor activity
    • Goishi, K., Higashiyama, S., Klagsbrun, M., Nakano, N., Umata, T., Ishikawa, M., et al. (1995) Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity. Mol Biol Cell 6: 967-980.
    • (1995) Mol Biol Cell , vol.6 , pp. 967-980
    • Goishi, K.1    Higashiyama, S.2    Klagsbrun, M.3    Nakano, N.4    Umata, T.5    Ishikawa, M.6
  • 12
    • 0025904265 scopus 로고
    • A heparin-binding growth factor secreted by rnacrophage-like cells that is related to EGF
    • Higashiyama, S., Abraham, J.A., Miller, J., Fiddes, J.C., and Klagsbrun, M. (1991) A heparin-binding growth factor secreted by rnacrophage-like cells that is related to EGF. Science 251: 936-939.
    • (1991) Science , vol.251 , pp. 936-939
    • Higashiyama, S.1    Abraham, J.A.2    Miller, J.3    Fiddes, J.C.4    Klagsbrun, M.5
  • 13
    • 0026673961 scopus 로고
    • Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein
    • Higashiyama, S., Lau, K., Besner, G.E., Abraham, J.A., and Klagsbrun, M. (1992) Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein. J Biol Chem 267: 6205-6212.
    • (1992) J Biol Chem , vol.267 , pp. 6205-6212
    • Higashiyama, S.1    Lau, K.2    Besner, G.E.3    Abraham, J.A.4    Klagsbrun, M.5
  • 14
    • 0028963636 scopus 로고
    • The membrane protein CD9/DRAP27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor
    • Higashiyama, S., Iwamoto, R., Goishi, K., Raab, G., Taniguchi, N., Klagsbrun, M., et al. (1995) The membrane protein CD9/DRAP27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor. J Cell Biol 128: 929-938.
    • (1995) J Cell Biol , vol.128 , pp. 929-938
    • Higashiyama, S.1    Iwamoto, R.2    Goishi, K.3    Raab, G.4    Taniguchi, N.5    Klagsbrun, M.6
  • 15
    • 0028924864 scopus 로고
    • Localization of a critical diphtheria toxin-binding domain to the C- Terminus of the mature heparin-binding EGF-like growth factor region of the diphtheria toxin receptor
    • Hooper, K.P., and Eidels, L. (1995) Localization of a critical diphtheria toxin-binding domain to the C-terminus of the mature heparin-binding EGF-like growth factor region of the diphtheria toxin receptor. Biochem Biophys Res Commun 206: 710-717.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 710-717
    • Hooper, K.P.1    Eidels, L.2
  • 16
    • 0029893228 scopus 로고    scopus 로고
    • Glutamic acid 141 of the diphtheria toxin receptor (HB-EGF precursor) is critical for toxin binding and toxin sensitivity
    • Hooper, K.P., and Eidels, L. (1996) Glutamic acid 141 of the diphtheria toxin receptor (HB-EGF precursor) is critical for toxin binding and toxin sensitivity. Biochem Biophys Res Commun 220: 675-680.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 675-680
    • Hooper, K.P.1    Eidels, L.2
  • 17
    • 0025837419 scopus 로고
    • An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor
    • Iwamoto, R., Senoh, H., Okada, Y., Uchida, T., and Mekada, E. (1991) An antibody that inhibits the binding of diphtheria toxin to cells revealed the association of a 27-kDa membrane protein with the diphtheria toxin receptor. J Biol Chem 266: 20463-20469.
    • (1991) J Biol Chem , vol.266 , pp. 20463-20469
    • Iwamoto, R.1    Senoh, H.2    Okada, Y.3    Uchida, T.4    Mekada, E.5
  • 18
    • 0028284810 scopus 로고
    • Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity
    • Iwamoto, R., Higashiyama, S., Mitamura, T., Taniguchi, N., Klagsbrun, M., and Mekada, E. (1994) Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity. EMBO J 13: 2322-2330.
    • (1994) EMBO J , vol.13 , pp. 2322-2330
    • Iwamoto, R.1    Higashiyama, S.2    Mitamura, T.3    Taniguchi, N.4    Klagsbrun, M.5    Mekada, E.6
  • 19
    • 0031305240 scopus 로고    scopus 로고
    • Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor
    • Louie, G.V., Yang, W., Bowman, M.E., and Choe, S. (1997) Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor. Mol Cell 1: 67-78.
    • (1997) Mol Cell , vol.1 , pp. 67-78
    • Louie, G.V.1    Yang, W.2    Bowman, M.E.3    Choe, S.4
  • 20
    • 0017350046 scopus 로고
    • Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae: Differential cytotoxicity
    • Middlebrook, J.L., and Dorland, R.B. (1977) Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtheriae: differential cytotoxicity. Can J Microbiol 23: 183-189.
    • (1977) Can J Microbiol , vol.23 , pp. 183-189
    • Middlebrook, J.L.1    Dorland, R.B.2
  • 21
    • 0021222922 scopus 로고
    • Bacterial toxins: Cellular mechanisms of action
    • Middlebrook, J.L., and Dorland, R.B. (1984) Bacterial toxins: cellular mechanisms of action. Microbiol Rev 48: 199-221.
    • (1984) Microbiol Rev , vol.48 , pp. 199-221
    • Middlebrook, J.L.1    Dorland, R.B.2
  • 22
    • 0018068693 scopus 로고
    • Association of diphtheria toxin with Vero cells. Demonstration of a receptor
    • Middlebrook, J.L., Dorland, R.B., and Leppla, S.H. (1978) Association of diphtheria toxin with Vero cells. Demonstration of a receptor. J Biol Chem 253: 7325-7330.
    • (1978) J Biol Chem , vol.253 , pp. 7325-7330
    • Middlebrook, J.L.1    Dorland, R.B.2    Leppla, S.H.3
  • 23
    • 0026914870 scopus 로고
    • The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from Vero cells is the monkey homologue of human CD9 antigen: Expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells
    • Mitamura, T., Iwamoto, R., Umata, T., Yomo, T., Urabe, I., Tsuneoka, M., et al. (1992) The 27-kD diphtheria toxin receptor-associated protein (DRAP27) from Vero cells is the monkey homologue of human CD9 antigen: expression of DRAP27 elevates the number of diphtheria toxin receptors on toxin-sensitive cells. J Cell Biol 118: 1389-1399.
    • (1992) J Cell Biol , vol.118 , pp. 1389-1399
    • Mitamura, T.1    Iwamoto, R.2    Umata, T.3    Yomo, T.4    Urabe, I.5    Tsuneoka, M.6
  • 24
    • 0028860250 scopus 로고
    • Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity
    • Mitamura, T., Higashiyama, S., Taniguchi, N., Klagsbrun, M., and Mekada, E. (1995) Diphtheria toxin binds to the epidermal growth factor (EGF)-like domain of human heparin-binding EGF-like growth factor/diphtheria toxin receptor and inhibits specifically its mitogenic activity. J Biol Chem 270: 1015-1019.
    • (1995) J Biol Chem , vol.270 , pp. 1015-1019
    • Mitamura, T.1    Higashiyama, S.2    Taniguchi, N.3    Klagsbrun, M.4    Mekada, E.5
  • 25
    • 0030779109 scopus 로고    scopus 로고
    • Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis
    • Mitamura, T., Umata, T., Nakano, F., Shishido, Y., Toyoda, T., Itai, A., et al. (1997) Structure-function analysis of the diphtheria toxin receptor toxin binding site by site-directed mutagenesis. J Biol Chem 272: 27084-27090.
    • (1997) J Biol Chem , vol.272 , pp. 27084-27090
    • Mitamura, T.1    Umata, T.2    Nakano, F.3    Shishido, Y.4    Toyoda, T.5    Itai, A.6
  • 26
    • 15144343092 scopus 로고
    • Preparation of genomic DNA from monolayer cells for DMS footprinting
    • Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., et al. (eds). New York: John Wiley & Sons
    • Mueller, P.R., Garrity, P.A., and Wold, B. (1995) Preparation of genomic DNA from monolayer cells for DMS footprinting. In Current Protocols in Molecular Biology, Vol. 2. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., et al. (eds). New York: John Wiley & Sons, pp. 15.5.8-13.
    • (1995) Current Protocols in Molecular Biology , vol.2 , pp. 1558-1613
    • Mueller, P.R.1    Garrity, P.A.2    Wold, B.3
  • 27
    • 0026747170 scopus 로고
    • Expression cloning of a diphtheria toxin receptor: Identity with a heparin-binding EGF-like growth factor precursor
    • Naglich, J.G., Metherall, J.E., Russell, D.W., and Eidels, L. (1992) Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell 69: 1051-1061.
    • (1992) Cell , vol.69 , pp. 1051-1061
    • Naglich, J.G.1    Metherall, J.E.2    Russell, D.W.3    Eidels, L.4
  • 29
    • 0015396782 scopus 로고
    • An immunological study of the diphtheria toxin molecule
    • Pappenheimer, Jr, A.M., Uchida, T., and Harper, A.A. (1972) An immunological study of the diphtheria toxin molecule. Immunochemistry 9: 891-906.
    • (1972) Immunochemistry , vol.9 , pp. 891-906
    • Pappenheimer Jr., A.M.1    Uchida, T.2    Harper, A.A.3
  • 30
    • 0019513816 scopus 로고
    • Diphtheria toxin: Receptor interaction. Characterization of the receptor interaction with the nucleotide-free toxin, the nucleotide-bound toxin, and the B-fragment of the toxin
    • Proia, R.L., Eidels, L., and Hart, D.A. (1981) Diphtheria toxin: receptor interaction. Characterization of the receptor interaction with the nucleotide-free toxin, the nucleotide-bound toxin, and the B-fragment of the toxin. J Biol Chem 256: 4991-4997.
    • (1981) J Biol Chem , vol.256 , pp. 4991-4997
    • Proia, R.L.1    Eidels, L.2    Hart, D.A.3
  • 31
    • 0026486829 scopus 로고
    • Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells
    • Temizer, D.H., Yoshizumi, M., Perrella, M.A., Susanni, E.E., Quertermous, T., and Lee, M.E. (1992) Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells. J Biol Chem 267: 24892-24896.
    • (1992) J Biol Chem , vol.267 , pp. 24892-24896
    • Temizer, D.H.1    Yoshizumi, M.2    Perrella, M.A.3    Susanni, E.E.4    Quertermous, T.5    Lee, M.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.