γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer

Immunity

Volumn 40, Issue 5, 2014, Pages 785-800

  Wu, Pin ^a,b   Wu, Dang ^a,b   Ni, Chao ^a,b   Ye, Jun ^a,b   Chen, Wuzhen ^b   Hu, Guoming ^a,b   Wang, Zhen ^a,b   Wang, Changrong ^b   Zhang, Zhigang ^b   Xia, Wenjie ^b   Chen, Zhigang ^a,b   Wang, Ke ^b   Zhang, Tao ^a   Xu, Jinghong ^b   Han, Yuehua ^b   Zhang, Ting ^a,b   Wu, Xianguo ^b   Wang, Jianwei ^b   Gong, Weihua ^b   Zheng, Shu ^a   Qiu, Fuming ^a,b   Yan, Jun ^c   Huang, Jian ^a,b   more..

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 8; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CANCER GROWTH; CANCER STAGING; CD3+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL EXPANSION; CELL INFILTRATION; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; GAMMA DELTA T LYMPHOCYTE; GAMMA DELTA T17 LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATION; LYMPHOID CELL; MAJOR CLINICAL STUDY; MYELOID DERIVED SUPPRESSOR CELL; POLARIZATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SUPPRESSOR CELL; T LYMPHOCYTE; TH17 CELL;

CELL PROLIFERATION; COLORECTAL NEOPLASMS; DENDRITIC CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-8; LYMPHOCYTE ACTIVATION; MYELOID CELLS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; TH17 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84900482064     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.03.013     Document Type: Article

References (38)

1. Balkwill F., Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 2001, 357:539-545.
2. Balkwill F., Charles K.A., Mantovani A. Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005, 7:211-217.
3. Caccamo N., La Mendola C., Orlando V., Meraviglia S., Todaro M., Stassi G., Sireci G., Fournié J.J., Dieli F. Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 Tcells. Blood 2011, 118:129-138.
4. Cai Y., Shen X., Ding C., Qi C., Li K., Li X., Jala V.R., Zhang H.G., Wang T., Zheng J., Yan J. Pivotal role of dermal IL-17-producing γδ Tcells in skin inflammation. Immunity 2011, 35:596-610.
5. Chung A.S., Wu X., Zhuang G., Ngu H., Kasman I., Zhang J., Vernes J.M., Jiang Z., Meng Y.G., Peale F.V., et al. An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy. Nat. Med. 2013, 19:1114-1123.
6. Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
7. Fenoglio D., Poggi A., Catellani S., Battaglia F., Ferrera A., Setti M., Murdaca G., Zocchi M.R. Vdelta1T lymphocytes producing IFN-gamma and IL-17 are expanded in HIV-1-infected patients and respond to Candida albicans. Blood 2009, 113:6611-6618.
8. Gabrilovich D.I., Ostrand-Rosenberg S., Bronte V. Coordinated regulation of myeloid cells by tumours. Nat. Rev. Immunol. 2012, 12:253-268.
9. Gray E.E., Ramírez-Valle F., Xu Y., Wu S., Wu Z., Karjalainen K.E., Cyster J.G. Deficiency in IL-17-committed Vγ4(+) γδ Tcells in a spontaneous Sox13-mutant CD45.1(+) congenic mouse substrain provides protection from dermatitis. Nat. Immunol. 2013, 14:584-592.
10. Grivennikov S.I., Greten F.R., Karin M. Immunity, inflammation, and cancer. Cell 2010, 140:883-899.
11. Grivennikov S.I., Wang K., Mucida D., Stewart C.A., Schnabl B., Jauch D., Taniguchi K., Yu G.Y., Osterreicher C.H., Hung K.E., et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012, 491:254-258.
12. He D., Li H., Yusuf N., Elmets C.A., Li J., Mountz J.D., Xu H. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J.Immunol. 2010, 184:2281-2288.
13. Hedrick M.N., Lonsdorf A.S., Shirakawa A.K., Richard Lee C.C., Liao F., Singh S.P., Zhang H.H., Grinberg A., Love P.E., Hwang S.T., Farber J.M. CCR6 is required for IL-23-induced psoriasis-like inflammation in mice. J.Clin. Invest. 2009, 119:2317-2329.
14. Hooper L.V., Littman D.R., Macpherson A.J. Interactions between the microbiota and the immune system. Science 2012, 336:1268-1273.
15. Kapanadze T., Gamrekelashvili J., Ma C., Chan C., Zhao F., Hewitt S., Zender L., Kapoor V., Felsher D.W., Manns M.P., et al. Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma. J.Hepatol. 2013, 59:1007-1013.
16. Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006, 441:431-436.
17. Kenna T.J., Davidson S.I., Duan R., Bradbury L.A., McFarlane J., Smith M., Weedon H., Street S., Thomas R., Thomas G.P., Brown M.A. Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ Tcells in patients with active ankylosing spondylitis. Arthritis Rheum. 2012, 64:1420-1429.
18. Langowski J.L., Zhang X., Wu L., Mattson J.D., Chen T., Smith K., Basham B., McClanahan T., Kastelein R.A., Oft M. IL-23 promotes tumour incidence and growth. Nature 2006, 442:461-465.
19. Mantovani A., Allavena P., Sica A., Balkwill F. Cancer-related inflammation. Nature 2008, 454:436-444.
20. Pantelyushin S., Haak S., Ingold B., Kulig P., Heppner F.L., Navarini A.A., Becher B. Rorγt+ innate lymphocytes and γδ Tcells initiate psoriasiform plaque formation in mice. J.Clin. Invest. 2012, 122:2252-2256.
21. Park S.G., Mathur R., Long M., Hosh N., Hao L., Hayden M.S., Ghosh S. T regulatory cells maintain intestinal homeostasis by suppressing γδ Tcells. Immunity 2010, 33:791-803.
22. Petermann F., Rothhammer V., Claussen M.C., Haas J.D., Blanco L.R., Heink S., Prinz I., Hemmer B., Kuchroo V.K., Oukka M., Korn T. γδ Tcells enhance autoimmunity by restraining regulatory Tcell responses via an interleukin-23-dependent mechanism. Immunity 2010, 33:351-363.
23. Reichling T., Goss K.H., Carson D.J., Holdcraft R.W., Ley-Ebert C., Witte D., Aronow B.J., Groden J. Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. Cancer Res. 2005, 65:166-176.
24. Rothwell P.M., Wilson M., Elwin C.E., Norrving B., Algra A., Warlow C.P., Meade T.W. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet 2010, 376:1741-1750.
25. Sade-Feldman M., Kanterman J., Ish-Shalom E., Elnekave M., Horwitz E., Baniyash M. Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation. Immunity 2013, 38:541-554.
26. Segura E., Touzot M., Bohineust A., Cappuccio A., Chiocchia G., Hosmalin A., Dalod M., Soumelis V., Amigorena S. Human inflammatory dendritic cells induce Th17 cell differentiation. Immunity 2013, 38:336-348.
27. Shichita T., Sugiyama Y., Ooboshi H., Sugimori H., Nakagawa R., Takada I., Iwaki T., Okada Y., Iida M., Cua D.J., et al. Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat. Med. 2009, 15:946-950.
28. Silva-Santos B. Promoting angiogenesis within the tumor microenvironment: the secret life of murine lymphoid IL-17-producing gammadelta Tcells. Eur. J. Immunol. 2010, 40:1873-1876.
29. Sutton C.E., Lalor S.J., Sweeney C.M., Brereton C.F., Lavelle E.C., Mills K.H. Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta Tcells, amplifying Th17 responses and autoimmunity. Immunity 2009, 31:331-341.
30. Tosolini M., Kirilovsky A., Mlecnik B., Fredriksen T., Mauger S., Bindea G., Berger A., Bruneval P., Fridman W.H., Pagès F., Galon J. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res. 2011, 71:1263-1271.
31. Vantourout P., Hayday A. Six-of-the-best: unique contributions of γδ Tcells to immunology. Nat. Rev. Immunol. 2013, 13:88-100.
32. Wakita D., Sumida K., Iwakura Y., Nishikawa H., Ohkuri T., Chamoto K., Kitamura H., Nishimura T. Tumor-infiltrating IL-17-producing gammadelta Tcells support the progression of tumor by promoting angiogenesis. Eur. J. Immunol. 2010, 40:1927-1937.
33. Wang X., Tully O., Ngo B., Zitin M., Mullin J.M. Epithelial tight junctional changes in colorectal cancer tissues. ScientificWorldJournal 2011, 11:826-841.
34. Wang X., Sun R., Wei H., Tian Z. High-mobility group box 1 (HMGB1)-Toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of γδ Tcells with macrophages. Hepatology 2013, 57:373-384.
35. Wood L.D., Parsons D.W., Jones S., Lin J., Sjöblom T., Leary R.J., Shen D., Boca S.M., Barber T., Ptak J., et al. The genomic landscapes of human breast and colorectal cancers. Science 2007, 318:1108-1113.
36. Wu S., Rhee K.J., Albesiano E., Rabizadeh S., Wu X., Yen H.R., Huso D.L., Brancati F.L., Wick E., McAllister F., et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 Tcell responses. Nat. Med. 2009, 15:1016-1022.
37. Zhao X., Rong L., Zhao X., Li X., Liu X., Deng J., Wu H., Xu X., Erben U., Wu P., et al. TNF signaling drives myeloid-derived suppressor cell accumulation. J.Clin. Invest. 2012, 122:4094-4104.
38. Zou W., Restifo N.P. T(H)17 cells in tumour immunity and immunotherapy. Nat. Rev. Immunol. 2010, 10:248-256.