Mitochondrial retrograde signaling induces epithelial–mesenchymal transition and generates breast cancer stem cells

Oncogene

Volumn 33, Issue 45, 2014, Pages 5238-5250

  Guha, M ^a   Srinivasan, S ^a   Ruthel, G ^a   Kashina, A K ^a   Carstens, R P ^b   Mendoza, A ^c   Khanna, C ^c   Van Winkle, T ^a   Avadhani, N G ^a  

^a School of Veterinary Medicine   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

breast cancer; cancer stem cells; epithelial mesenchymal transition; ESRP1; mitochondrial DNA; mitochondrial retrograde signaling

Indexed keywords

CALCINEURIN; DNA BINDING PROTEIN; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; PPP3CA PROTEIN, HUMAN; TFAM PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ANIMAL; BREAST TUMOR; CANCER STEM CELL; CELL LINE; CELL MOTION; CONFOCAL MICROSCOPY; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FEMALE; GENE DOSAGE; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOBLOTTING; LUNG TUMOR; MCF 7 CELL LINE; METABOLISM; MITOCHONDRION; OXYGEN CONSUMPTION; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SCID MOUSE; SECONDARY; SIGNAL TRANSDUCTION; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; CALCINEURIN; CELL LINE; CELL MOVEMENT; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE DOSAGE; GENE EXPRESSION; HUMANS; IMMUNOBLOTTING; LUNG NEOPLASMS; MCF-7 CELLS; MICE, SCID; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEOPLASTIC STEM CELLS; OXYGEN CONSUMPTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 85028213338     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.467     Document Type: Article

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