Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1797, Issue 6-7, 2010, Pages 1055-1065

  Guha, Manti ^a   Tang, Weigang ^a   Sondheimer, Neal ^a   Avadhani, Narayan G ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Akt1 activation; Calcineurin activation; HnRNPA2 as a coactivator; Mitochondrial respiratory stress; Retrograde signaling

Indexed keywords

CALCINEURIN; CATHEPSIN L; CCAAT ENHANCER BINDING PROTEIN DELTA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOSE TRANSPORTER 4; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATASE; PROTEIN KINASE B; RYANODINE RECEPTOR 1; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE SILENCING; GLUCOSE TRANSPORT; METABOLIC STRESS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CALCINEURIN; CATHEPSIN L; CELL LINE; CELL NUCLEUS; DNA, MITOCHONDRIAL; GENE KNOCKDOWN TECHNIQUES; GLUCOSE; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HUMANS; MICE; MITOCHONDRIA; MODELS, BIOLOGICAL; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; RNA, SMALL INTERFERING; STRESS, PHYSIOLOGICAL; TRANSCRIPTIONAL ACTIVATION;

MAMMALIA;

EID: 77953806964     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2010.02.008     Document Type: Article

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