Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells

European Journal of Cancer Prevention

Volumn 18, Issue 6, 2009, Pages 445-457

  Yu, Man ^a,b,c   Shi, Yurong ^a   Wei, Xiyin ^a   Yang, Yi ^a   Zang, Fenglin ^a   Niu, Ruifang ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Antioxidant defense; Apoptosis; Breast cancer; Drug resistance; Mitochondrial DNA; Oxidative stress; T47D o cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATALASE; DOXORUBICIN; FAS ANTIBODY; GLUTATHIONE PEROXIDASE; GLYCOPROTEIN P; LACTATE DEHYDROGENASE; LACTIC ACID; MITOCHONDRIAL DNA; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; SUPEROXIDE DISMUTASE; VINCRISTINE;

APOPTOSIS; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL DNA DEPLETION; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY CHAIN; UPREGULATION; WILD TYPE;

ADENOSINE TRIPHOSPHATE; ANTIBIOTICS, ANTINEOPLASTIC; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CATALASE; DNA, MITOCHONDRIAL; DOXORUBICIN; ENZYME INHIBITORS; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; L-LACTATE DEHYDROGENASE; LACTIC ACID; MITOCHONDRIA; OXIDATIVE STRESS; OXYGEN CONSUMPTION; P-GLYCOPROTEIN; PACLITAXEL; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAUROSPORINE; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED; VINCRISTINE;

EID: 70349823621     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/CEJ.0b013e32832f9bd6     Document Type: Article

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