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Volumn 8, Issue 1, 2016, Pages

Effect of Cichorium intybus L. on the expression of hepatic NF-κB and IKKβ and serum TNF-α in STZ-and STZ+ niacinamide-induced diabetes in rats

Author keywords

Chicory; Diabetes type 2; IKK ; Inflammatory cytokines; NF B; TNF

Indexed keywords

ACETYLSALICYLIC ACID; ANTIDIABETIC AGENT; CICHORIUM INTYBUS EXTRACT; GLUCOSE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MESSENGER RNA; METFORMIN; NICOTINAMIDE; PLANT EXTRACT; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 85027949211     PISSN: None     EISSN: 17585996     Source Type: Journal    
DOI: 10.1186/s13098-016-0128-6     Document Type: Article
Times cited : (38)

References (51)
  • 1
    • 78649442666 scopus 로고    scopus 로고
    • Diabetes and inflammation: Fundamental aspects and clinical implications
    • Garcia C, Feve B, Ferre P, Halimi S, Baizri H, Bordier L, et al. Diabetes and inflammation: fundamental aspects and clinical implications. Diabetes Metab. 2010;36(5):327-38.
    • (2010) Diabetes Metab. , vol.36 , Issue.5 , pp. 327-338
    • Garcia, C.1    Feve, B.2    Ferre, P.3    Halimi, S.4    Baizri, H.5    Bordier, L.6
  • 2
    • 84929501223 scopus 로고    scopus 로고
    • Chronic superantigen exposure induces systemic inflammation, elevated bloodstream endotoxin, and abnormal glucose tolerance in rabbits: Possible role in diabetes
    • Vu BG, Stach CS, Kulhankova K, Salgado-Pabon W, Klingelhutz AJ, Schlievert PM. Chronic superantigen exposure induces systemic inflammation, elevated bloodstream endotoxin, and abnormal glucose tolerance in rabbits: possible role in diabetes. MBio. 2015;6(2):e02554.doi:10.1128/mBio.02554-14.
    • (2015) MBio. , vol.6 , Issue.2 , pp. e02554
    • Vu, B.G.1    Stach, C.S.2    Kulhankova, K.3    Salgado-Pabon, W.4    Klingelhutz, A.J.5    Schlievert, P.M.6
  • 3
    • 84863455384 scopus 로고    scopus 로고
    • Inflammation and type 2 diabetes
    • Calle MC, Fernandez ML. Inflammation and type 2 diabetes. Diabetes Metab. 2012;38(3):183-91.
    • (2012) Diabetes Metab. , vol.38 , Issue.3 , pp. 183-191
    • Calle, M.C.1    Fernandez, M.L.2
  • 4
    • 4644297155 scopus 로고    scopus 로고
    • Changes in circulating postprandial proinflammatory cytokine concentrations in diet-controlled type 2 diabetes and the effect of ingested fat
    • Manning PJ, Sutherland WH, Hendry G, de Jong SA, McGrath M, Williams SM. Changes in circulating postprandial proinflammatory cytokine concentrations in diet-controlled type 2 diabetes and the effect of ingested fat. Diabetes Care. 2004;27(10):2509-11.
    • (2004) Diabetes Care. , vol.27 , Issue.10 , pp. 2509-2511
    • Manning, P.J.1    Sutherland, W.H.2    Hendry, G.3    De Jong, S.A.4    McGrath, M.5    Williams, S.M.6
  • 5
    • 19344366005 scopus 로고    scopus 로고
    • Is NF-kappaB a culprit in type 2 diabetes?
    • Chen F. Is NF-kappaB a culprit in type 2 diabetes? Biochem Biophys Res Commun. 2005;332(1):1-3.
    • (2005) Biochem Biophys Res Commun. , vol.332 , Issue.1 , pp. 1-3
    • Chen, F.1
  • 6
    • 13844299421 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain
    • Csehi S-B, Mathieu S, Seifert U, Lange A, Zweyer M, Wernig A, et al. Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain. Biochem Biophys Res Commun. 2005;329(1):397-405.
    • (2005) Biochem Biophys Res Commun. , vol.329 , Issue.1 , pp. 397-405
    • Csehi, S.-B.1    Mathieu, S.2    Seifert, U.3    Lange, A.4    Zweyer, M.5    Wernig, A.6
  • 7
    • 0030206997 scopus 로고    scopus 로고
    • Inhibition of insulin receptor signaling by TNF: Potential role in obesity and non-insulin-dependent diabetes mellitus
    • Skolnik EY, Marcusohn J. Inhibition of insulin receptor signaling by TNF: potential role in obesity and non-insulin-dependent diabetes mellitus. Cytokine Growth F R. 1996;7(2):161-73.
    • (1996) Cytokine Growth F R. , vol.7 , Issue.2 , pp. 161-173
    • Skolnik, E.Y.1    Marcusohn, J.2
  • 8
    • 77954730556 scopus 로고    scopus 로고
    • Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1, 2-dimethylhydrazine-induced rat colon carcinogenesis
    • Umesalma S, Sudhandiran G. Differential inhibitory effects of the polyphenol ellagic acid on inflammatory mediators NF-kappaB, iNOS, COX-2, TNF-alpha, and IL-6 in 1, 2-dimethylhydrazine-induced rat colon carcinogenesis. Basic Clin Pharmacol Toxicol. 2010;107(2):650-5.
    • (2010) Basic Clin Pharmacol Toxicol. , vol.107 , Issue.2 , pp. 650-655
    • Umesalma, S.1    Sudhandiran, G.2
  • 9
    • 84871717518 scopus 로고    scopus 로고
    • Phytochemicals and their impact on adipose tissue inflammation and diabetes
    • Leiherer A, Mundlein A, Drexel H. Phytochemicals and their impact on adipose tissue inflammation and diabetes. Vasc Pharmacol. 2013;58:3-20.
    • (2013) Vasc Pharmacol. , vol.58 , pp. 3-20
    • Leiherer, A.1    Mundlein, A.2    Drexel, H.3
  • 10
    • 40549100352 scopus 로고    scopus 로고
    • Anti-hepatotoxic activity of cichotyboside, a sesquiterpene glycoside from the seeds of Cichorium intybus
    • Ahmed B, Khan S, Masood MH, Siddique AH. Anti-hepatotoxic activity of cichotyboside, a sesquiterpene glycoside from the seeds of Cichorium intybus. J Asian Nat Prod Res. 2008;10(3):223-31.
    • (2008) J Asian Nat Prod Res. , vol.10 , Issue.3 , pp. 223-231
    • Ahmed, B.1    Khan, S.2    Masood, M.H.3    Siddique, A.H.4
  • 11
    • 84887415777 scopus 로고    scopus 로고
    • Antihyperglycemic effect of a natural chicoric acid extract of chicory (Cichorium intybus L.): A comparative in vitro study with the effects of caffeic and ferulic acids
    • Azay-Milhau J, Ferrare K, Leroy J, Aubaterre J, Tournier M, Lajoix A-D, et al. Antihyperglycemic effect of a natural chicoric acid extract of chicory (Cichorium intybus L.): a comparative in vitro study with the effects of caffeic and ferulic acids. J Ethnopharmacol. 2013;150(2):755-60.
    • (2013) J Ethnopharmacol. , vol.150 , Issue.2 , pp. 755-760
    • Azay-Milhau, J.1    Ferrare, K.2    Leroy, J.3    Aubaterre, J.4    Tournier, M.5    Lajoix, A.-D.6
  • 12
    • 84927103294 scopus 로고    scopus 로고
    • Impact of chicory-supplemented diet on HMG-CoA reductase, acetyl-CoA carboxylase, visfatin and anti-oxidant status in triton WR-1339-induced hyperlipidemia
    • Keshk WA, Noeman SA. Impact of chicory-supplemented diet on HMG-CoA reductase, acetyl-CoA carboxylase, visfatin and anti-oxidant status in triton WR-1339-induced hyperlipidemia. J Food Biochem. 2015;39(2):164-72.
    • (2015) J Food Biochem. , vol.39 , Issue.2 , pp. 164-172
    • Keshk, W.A.1    Noeman, S.A.2
  • 13
    • 84942834924 scopus 로고    scopus 로고
    • Chicory, a typical vegetable in mediterranean diet, exerts a therapeutic role in established atherosclerosis in apolipoprotein E-deficient mice
    • Lin W, Liu C, Yang H, Wang W, Ling W, Wang D. Chicory, a typical vegetable in mediterranean diet, exerts a therapeutic role in established atherosclerosis in apolipoprotein E-deficient mice. Mol Nutr Food Res. 2015;59(9):1-11.
    • (2015) Mol Nutr Food Res. , vol.59 , Issue.9 , pp. 1-11
    • Lin, W.1    Liu, C.2    Yang, H.3    Wang, W.4    Ling, W.5    Wang, D.6
  • 15
    • 84905256071 scopus 로고    scopus 로고
    • Ameliorating effect of chicory (Chichorium intybus L.) fruit extract against 4-tertoctylphenol induced liver injury and oxidative stress in male rats
    • Saggu S, Sakeran MI, Zidan N, Tousson E, Mohan A, Rehman H. Ameliorating effect of chicory (Chichorium intybus L.) fruit extract against 4-tertoctylphenol induced liver injury and oxidative stress in male rats. Food Chem Toxicol. 2014;72:138-46.
    • (2014) Food Chem Toxicol. , vol.72 , pp. 138-146
    • Saggu, S.1    Sakeran, M.I.2    Zidan, N.3    Tousson, E.4    Mohan, A.5    Rehman, H.6
  • 16
    • 84881280686 scopus 로고    scopus 로고
    • Chicoric acid prevents obesity by attenuating hepatic steatosis, inflammation and oxidative stress in high-fat diet-fed mice
    • Xiao H, Xie G, Wang J, Hou X, Wang X, Wu W, et al. Chicoric acid prevents obesity by attenuating hepatic steatosis, inflammation and oxidative stress in high-fat diet-fed mice. Food Res Int. 2013;54(1):345-53.
    • (2013) Food Res Int. , vol.54 , Issue.1 , pp. 345-353
    • Xiao, H.1    Xie, G.2    Wang, J.3    Hou, X.4    Wang, X.5    Wu, W.6
  • 17
    • 84955202441 scopus 로고    scopus 로고
    • Phytochemical, antioxidant and mineral composition of hydroalcoholic extract of chicory (Cichorium intybus L.) leaves. Saudi
    • Abbas ZK, Saggu S, Sakeran MI, Zidan N, Rehman H, Ansari AA. Phytochemical, antioxidant and mineral composition of hydroalcoholic extract of chicory (Cichorium intybus L.) leaves. Saudi. J Biol Sci. 2015;22(3):322-6.
    • (2015) J Biol Sci. , vol.22 , Issue.3 , pp. 322-326
    • Abbas, Z.K.1    Saggu, S.2    Sakeran, M.I.3    Zidan, N.4    Rehman, H.5    Ansari, A.A.6
  • 18
    • 84940166511 scopus 로고    scopus 로고
    • Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties
    • Nishimura M, Ohkawara T, Kanayama T, Kitagawa K, Nishimura H, Nishihira J. Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties. J Tradit Complement Med. 2015;5(3):161-7.
    • (2015) J Tradit Complement Med. , vol.5 , Issue.3 , pp. 161-167
    • Nishimura, M.1    Ohkawara, T.2    Kanayama, T.3    Kitagawa, K.4    Nishimura, H.5    Nishihira, J.6
  • 19
    • 77954322447 scopus 로고    scopus 로고
    • Phase 1, placebocontrolled, dose escalation trial of chicory root extract in patients with osteoarthritis of the hip or knee
    • Olsen NJ, Branch VK, Jonnala G, Seskar M, Cooper M. Phase 1, placebocontrolled, dose escalation trial of chicory root extract in patients with osteoarthritis of the hip or knee. BMC Musculoskel Dis. 2010;11:156.
    • (2010) BMC Musculoskel Dis. , vol.11 , pp. 156
    • Olsen, N.J.1    Branch, V.K.2    Jonnala, G.3    Seskar, M.4    Cooper, M.5
  • 20
    • 79955549804 scopus 로고    scopus 로고
    • Thrombosis preventive potential of chicory coffee consumption: A clinical study
    • Schumacher E, Vigh E, Molnar V, Kenyeres P, Feher G, Kesmarky G, et al. Thrombosis preventive potential of chicory coffee consumption: a clinical study. Phytother Res. 2011;25(5):744-8.
    • (2011) Phytother Res. , vol.25 , Issue.5 , pp. 744-748
    • Schumacher, E.1    Vigh, E.2    Molnar, V.3    Kenyeres, P.4    Feher, G.5    Kesmarky, G.6
  • 21
    • 84872293751 scopus 로고    scopus 로고
    • Effect of chicory seed extract on glucose tolerance test (GTT) and metabolic profile in early and late stage diabetic rats
    • Ghamarian A, Abdollahi M, Su X, Amiri A, Ahadi A, Nowrouzi A. Effect of chicory seed extract on glucose tolerance test (GTT) and metabolic profile in early and late stage diabetic rats. Daru. 2012;20(1):56.
    • (2012) Daru. , vol.20 , Issue.1 , pp. 56
    • Ghamarian, A.1    Abdollahi, M.2    Su, X.3    Amiri, A.4    Ahadi, A.5    Nowrouzi, A.6
  • 22
    • 84877626901 scopus 로고    scopus 로고
    • Revisiting the mechanisms of metformin action in the liver
    • Viollet B, Foretz M. Revisiting the mechanisms of metformin action in the liver. Ann Endocrinol (Paris). 2013;74(2):123-9.
    • (2013) Ann Endocrinol (Paris). , vol.74 , Issue.2 , pp. 123-129
    • Viollet, B.1    Foretz, M.2
  • 23
    • 79951656816 scopus 로고    scopus 로고
    • Aspirin: Old drug, new uses and challenges
    • Yeomans ND. Aspirin: old drug, new uses and challenges. J Gastroen Hepatol. 2011;26(3):426-31.
    • (2011) J Gastroen Hepatol. , vol.26 , Issue.3 , pp. 426-431
    • Yeomans, N.D.1
  • 24
    • 78650831605 scopus 로고    scopus 로고
    • Aspirin use rates in diabetes: A systematic review cross-sectional study
    • Law EH, Simpson SH. Aspirin use rates in diabetes: a systematic review cross-sectional study. Can J Diabetes. 2010;34(3):211-7.
    • (2010) Can J Diabetes. , vol.34 , Issue.3 , pp. 211-217
    • Law, E.H.1    Simpson, S.H.2
  • 25
    • 14244269416 scopus 로고
    • On the treatment of glycosuria and diabetes mellitus with sodium salicylate
    • Williamson RT. On the treatment of glycosuria and diabetes mellitus with sodium salicylate. Brit Med J. 1901;1(2100):760-2.
    • (1901) Brit Med J. , vol.1 , Issue.2100 , pp. 760-762
    • Williamson, R.T.1
  • 26
    • 77954933558 scopus 로고    scopus 로고
    • Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
    • Foretz M, Hebrard S, Leclerc J, Zarrinpashneh E, Soty M, Mithieux G, et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. J Clin Invest. 2010;120(7):2355-69.
    • (2010) J Clin Invest. , vol.120 , Issue.7 , pp. 2355-2369
    • Foretz, M.1    Hebrard, S.2    Leclerc, J.3    Zarrinpashneh, E.4    Soty, M.5    Mithieux, G.6
  • 27
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.
    • (1976) Anal Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 28
    • 34047110361 scopus 로고    scopus 로고
    • Anti-diabetic effects of cichorium intybus in Streptozotocin-induced Diabetic Rats
    • Pushparaj PN, Low HK, Manikandan J, Tan BKH, Tan CH. Anti-diabetic effects of Cichorium intybus in streptozotocin-induced diabetic rats. J Ethnopharmacol. 2007;111(2):430-4.
    • (2007) J Ethnopharmacol. , vol.111 , Issue.2 , pp. 430-434
    • Pushparaj, P.N.1    Low, H.K.2    Manikandan, J.3    Bkh, T.4    Tan, C.H.5
  • 29
    • 79958296379 scopus 로고    scopus 로고
    • Effect of aspirin on the expression of hepatocyte NF-kappaB and serum TNF-alpha in streptozotocin-induced type 2 diabetic rats
    • Sun X, Han F, Yi J, Han L, Wang B. Effect of aspirin on the expression of hepatocyte NF-kappaB and serum TNF-alpha in streptozotocin-induced type 2 diabetic rats. J Korean Med Sci. 2011;26(6):765-70.
    • (2011) J Korean Med Sci. , vol.26 , Issue.6 , pp. 765-770
    • Sun, X.1    Han, F.2    Yi, J.3    Han, L.4    Wang, B.5
  • 30
    • 84931422596 scopus 로고    scopus 로고
    • Phenolics composition and antidiabetic property of Brachystegia eurycoma seed flour in high-fat diet, low-dose streptozotocin-induced type 2 diabetes in rats
    • Irondi EA, Oboh G, Akindahunsi AA, Boligon AA, Athayde ML. Phenolics composition and antidiabetic property of Brachystegia eurycoma seed flour in high-fat diet, low-dose streptozotocin-induced type 2 diabetes in rats. Asian Pac J Trop Dis. 2015;5(Supplement 1):S159-65.
    • (2015) Asian Pac J Trop Dis. , vol.5 , pp. S159-S165
    • Irondi, E.A.1    Oboh, G.2    Akindahunsi, A.A.3    Boligon, A.A.4    Athayde, M.L.5
  • 31
    • 67849111442 scopus 로고    scopus 로고
    • A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes
    • Chou TW, Ma CY, Cheng HH, Chen YY, Lai MH. A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes. J Clin Biochem Nutr. 2009;45(1):29-36.
    • (2009) J Clin Biochem Nutr. , vol.45 , Issue.1 , pp. 29-36
    • Chou, T.W.1    Ma, C.Y.2    Cheng, H.H.3    Chen, Y.Y.4    Lai, M.H.5
  • 32
    • 0031939587 scopus 로고    scopus 로고
    • Experimental NIDDM: Development of a new model in adult rats administered streptozotocin and nicotinamide
    • Masiello P, Broca C, Gross R, Roye M, Manteghetti M, Hillaire-Buys D, et al. Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide. Diabetes. 1998;47(2):224-9.
    • (1998) Diabetes. , vol.47 , Issue.2 , pp. 224-229
    • Masiello, P.1    Broca, C.2    Gross, R.3    Roye, M.4    Manteghetti, M.5    Hillaire-Buys, D.6
  • 33
    • 0036000246 scopus 로고    scopus 로고
    • Medicinal plants of India with anti-diabetic potential
    • Grover JK, Yadav S, Vats V. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol. 2002;8(1):81-100.
    • (2002) J Ethnopharmacol. , vol.8 , Issue.1 , pp. 81-100
    • Grover, J.K.1    Yadav, S.2    Vats, V.3
  • 34
    • 77956612338 scopus 로고    scopus 로고
    • Type 2 diabetes-related bioactivities of coffee: Assessment of antioxidant activity NF-κB inhibition and stimulation of glucose uptake
    • Chu Y-F, Chen Y, Black RM, Brown PH, Lyle BJ, Liu RH, et al. Type 2 diabetes-related bioactivities of coffee: assessment of antioxidant activity, NF-κB inhibition, and stimulation of glucose uptake. Food Chem. 2011;124(3):914-20.
    • (2011) Food Chem. , vol.124 , Issue.3 , pp. 914-920
    • Chu, Y.-F.1    Chen, Y.2    Black, R.M.3    Brown, P.H.4    Lyle, B.J.5    Liu, R.H.6
  • 35
    • 77957570183 scopus 로고    scopus 로고
    • Inhibiting NF-kappaB activation by small molecules as a therapeutic strategy
    • Gupta SC, Sundaram C, Reuter S, Aggarwal BB. Inhibiting NF-kappaB activation by small molecules as a therapeutic strategy. Biochim Biophys Acta. 2010;1799(10-12):775-87.
    • (2010) Biochim Biophys Acta. , vol.1799 , Issue.10-12 , pp. 775-787
    • Gupta, S.C.1    Sundaram, C.2    Reuter, S.3    Aggarwal, B.B.4
  • 36
    • 0041842588 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB by phenolic antioxidants: Interplay between antioxidant signaling and inflammatory cytokine expression
    • Ma Q, Kinneer K, Ye J, Chen BJ. Inhibition of nuclear factor kappaB by phenolic antioxidants: interplay between antioxidant signaling and inflammatory cytokine expression. Mol Pharmacol. 2003;64(2):211-9.
    • (2003) Mol Pharmacol. , vol.64 , Issue.2 , pp. 211-219
    • Ma, Q.1    Kinneer, K.2    Ye, J.3    Chen, B.J.4
  • 37
    • 70549093110 scopus 로고    scopus 로고
    • Role of NF-kappa B in the pathogenesis of diabetes and its associated complications
    • Patel S, Santani D. Role of NF-kappa B in the pathogenesis of diabetes and its associated complications. Pharmacol Rep. 2009;61(4):595-603.
    • (2009) Pharmacol Rep. , vol.61 , Issue.4 , pp. 595-603
    • Patel, S.1    Santani, D.2
  • 38
    • 85028256321 scopus 로고    scopus 로고
    • Cichorium intybus L. (CI) as an insulin sensitizer
    • Nowrouzi A, Pourfarjam Y, Amiri A. Cichorium intybus L. (CI) as an insulin sensitizer. Diabetes. 2013;62(Suppl 1):A304.
    • (2013) Diabetes. , vol.62 , pp. A304
    • Nowrouzi, A.1    Pourfarjam, Y.2    Amiri, A.3
  • 39
    • 85014303330 scopus 로고    scopus 로고
    • Antiinflammatory activity of roots of Cichorium intybus due to its inhibitory effect on various cytokines and antioxidant activity
    • Rizvi W, Fayazuddin M, Shariq S, Singh O, Moin S, Akhtar K, et al. Antiinflammatory activity of roots of Cichorium intybus due to its inhibitory effect on various cytokines and antioxidant activity. Anc Sci Life. 2014;34(1):44-9.
    • (2014) Anc Sci Life. , vol.34 , Issue.1 , pp. 44-49
    • Rizvi, W.1    Fayazuddin, M.2    Shariq, S.3    Singh, O.4    Moin, S.5    Akhtar, K.6
  • 40
    • 0033867178 scopus 로고    scopus 로고
    • Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes
    • Moller DE. Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab. 2000;11(6):212-7.
    • (2000) Trends Endocrinol Metab. , vol.11 , Issue.6 , pp. 212-217
    • Moller, D.E.1
  • 41
    • 78650920066 scopus 로고    scopus 로고
    • Non-canonical NF-kappaB signaling pathway
    • Sun SC. Non-canonical NF-kappaB signaling pathway. Cell Res. 2011;21(1):71-85.
    • (2011) Cell Res. , vol.21 , Issue.1 , pp. 71-85
    • Sun, S.C.1
  • 42
    • 77950520450 scopus 로고    scopus 로고
    • Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity
    • Kabuta T, Hakuno F, Cho Y, Yamanaka D, Chida K, Asano T, et al. Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity. Biochem Biophys Res Commun. 2010;394(3):697-702.
    • (2010) Biochem Biophys Res Commun. , vol.394 , Issue.3 , pp. 697-702
    • Kabuta, T.1    Hakuno, F.2    Cho, Y.3    Yamanaka, D.4    Chida, K.5    Asano, T.6
  • 44
    • 84877890083 scopus 로고    scopus 로고
    • Amelioration by chicory seed extract of diabetes-and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARalpha and SREBP-1
    • Ziamajidi N, Khaghani S, Hassanzadeh G, Vardasbi S, Ahmadian S, Nowrouzi A, et al. Amelioration by chicory seed extract of diabetes-and oleic acid-induced non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) via modulation of PPARalpha and SREBP-1. Food Chem Toxicol. 2013;58:198-209.
    • (2013) Food Chem Toxicol. , vol.58 , pp. 198-209
    • Ziamajidi, N.1    Khaghani, S.2    Hassanzadeh, G.3    Vardasbi, S.4    Ahmadian, S.5    Nowrouzi, A.6
  • 45
    • 33747253447 scopus 로고    scopus 로고
    • Aspirin and PPAR-α activators inhibit monocyte chemoattractant protein-1 expression induced by high glucose concentration in human endothelial cells
    • Dragomir E, Tircol M, Manduteanu I, Voinea M, Simionescu M. Aspirin and PPAR-α activators inhibit monocyte chemoattractant protein-1 expression induced by high glucose concentration in human endothelial cells. Vasc Pharmacol. 2006;44(6):440-9.
    • (2006) Vasc Pharmacol. , vol.44 , Issue.6 , pp. 440-449
    • Dragomir, E.1    Tircol, M.2    Manduteanu, I.3    Voinea, M.4    Simionescu, M.5
  • 46
    • 84862816917 scopus 로고    scopus 로고
    • Antidiabetic drug metformin alleviates endotoxin-induced fulminant liver injury in mice
    • Yuan H, Li L, Zheng W, Wan J, Ge P, Li H, et al. Antidiabetic drug metformin alleviates endotoxin-induced fulminant liver injury in mice. Int Immunopharmacol. 2012;12(4):682-8.
    • (2012) Int Immunopharmacol. , vol.12 , Issue.4 , pp. 682-688
    • Yuan, H.1    Li, L.2    Zheng, W.3    Wan, J.4    Ge, P.5    Li, H.6
  • 47
    • 77953739658 scopus 로고    scopus 로고
    • Metformin, an antidiabetic agent, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro
    • Arai M, Uchiba M, Komura H, Mizuochi Y, Harada N, Okajima K. Metformin, an antidiabetic agent, suppresses the production of tumor necrosis factor and tissue factor by inhibiting early growth response factor-1 expression in human monocytes in vitro. J Pharmacol Exp Ther. 2010;334(1):206-13.
    • (2010) J Pharmacol Exp Ther. , vol.334 , Issue.1 , pp. 206-213
    • Arai, M.1    Uchiba, M.2    Komura, H.3    Mizuochi, Y.4    Harada, N.5    Okajima, K.6
  • 48
    • 0032511210 scopus 로고    scopus 로고
    • Simple high-performance liquid chromatographic method for the determination of metformin in human plasma
    • Yuen KH, Peh KK. Simple high-performance liquid chromatographic method for the determination of metformin in human plasma. J Chromatogr B. 1998;710(1-2):243-6.
    • (1998) J Chromatogr B. , vol.710 , Issue.1-2 , pp. 243-246
    • Yuen, K.H.1    Peh, K.K.2
  • 49
    • 84962094356 scopus 로고    scopus 로고
    • The primary glucose-lowering effect of metformin resides in the Gut, not the circulation. Results from short-term Pharmacokinetic and 12-week doseranging studies
    • Buse JB, DeFronzo RA, Rosenstock J, Kim T, Burns C, Skare S, et al. The primary glucose-lowering effect of metformin resides in the Gut, not the circulation. results from short-term Pharmacokinetic and 12-week doseranging studies. Diabetes Care. 2015.doi:10.2337/dc15-0488.
    • (2015) Diabetes Care.
    • Buse, J.B.1    DeFronzo, R.A.2    Rosenstock, J.3    Kim, T.4    Burns, C.5    Skare, S.6
  • 51
    • 33751097948 scopus 로고    scopus 로고
    • Nutrition recommendations and interventions for diabetes-2006: A position statement of the American Diabetes Association
    • Bantle JP, Wylie-Rosett J, Albright AL, Apovian CM, Clark NG, Franz MJ, et al. Nutrition recommendations and interventions for diabetes-2006: a position statement of the American Diabetes Association. Diabetes Care. 2006;29(9):2140-57.
    • (2006) Diabetes Care. , vol.29 , Issue.9 , pp. 2140-2157
    • Bantle, J.P.1    Wylie-Rosett, J.2    Albright, A.L.3    Apovian, C.M.4    Clark, N.G.5    Franz, M.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.