2-(2′-Pyridyl) benzimidazole derivatives and their urease inhibitory activity

Medicinal Chemistry Research

Volumn 23, Issue 10, 2014, Pages 4447-4454

  Saify, Zafar Saeed ^a   Kamil, Arfa ^b   Akhtar, Shamim ^a   Taha, Muhammad ^c   Khan, Ajmal ^a   Khan, Khalid Mohammed ^a   Jahan, Sarwat ^b   Rahim, Fazal ^d   Perveen, Shahnaz ^e   Choudhary, M Iqbal ^a,f  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b FEDERAL URDU UNIVERSITY OF ARTS   (Pakistan)

^c UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^d HAZARA UNIVERSITY   (Pakistan)

^e PCSIR LABORATORIES COMPLEX   (Pakistan)

^f KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Peptic ulcer; Pyridyl benzimidazole analogues; SAR; Urease inhibition

Indexed keywords

1 (2 OXO 2 PHENYLETHYL) 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (2' NITROPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (2',4' DIFLUOROPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (2',5' DIMETHOXYPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (3' NITROPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (3',4' DIHYDROXYPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM CHLORIDE; 1 [2 (4 FLUOROPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (4' CHLOROPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (4' METHOXYPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 (4' NITROPHENYL) 2 OXOETHYL] 2 (2 PYRIDINYL) 1H BENZIMIDAZOL 1 IUM BROMIDE; 1 [2 [(1,1' BIPHENYL) 4 YL] 2 OXOETHYL] 2 (PYRIDIN 2 YL) 1H BENZO[D]IMIDAZOL 1 IUM; ACETOHYDROXAMIC ACID; BENZIMIDAZOLE DERIVATIVE; THIOUREA; UNCLASSIFIED DRUG; UREASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ELECTRON; ENZYME INHIBITION; STRUCTURE ACTIVITY RELATION;

EID: 85027926278     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-014-1015-z     Document Type: Article

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