An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis

Cell Reports

Volumn 20, Issue 7, 2017, Pages 1623-1640

  Walsh, Logan A ^a   Alvarez, Mariano J ^b,c   Sabio, Erich Y ^a   Reyngold, Marsha ^a   Makarov, Vladimir ^a   Mukherjee, Suranjit ^d   Lee, Ken Wing ^a   Desrichard, Alexis ^a   Turcan, Şevin ^a   Dalin, Martin G ^a   Rajasekhar, Vinagolu K ^a   Chen, Shuibing ^d   Vahdat, Linda T ^e   Califano, Andrea ^b   Chan, Timothy A ^a,d  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c DarwinHealth Inc   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

ARACNe; breast; cancer; EFP; MARINa; metastasis; transcription; TRIM25; VIPER

Indexed keywords

DNA; PROTEIN TRIM25; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTOME; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ESTROGEN RECEPTOR; LUCIFERASE; TRIM25 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; TUMOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PROGNOSIS; CANCER STEM CELL; CANCER SURVIVAL; CARCINOGENICITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; METASTATIC BREAST CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SYSTEMS BIOLOGY; TRANSCRIPTION REGULATION; ANIMAL; BREAST TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; LUNG TUMOR; METABOLISM; MORTALITY; NUDE MOUSE; PATHOLOGY; REPORTER GENE; SECONDARY; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; GENES, REPORTER; HETEROGRAFTS; HUMANS; LUCIFERASES; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM PROTEINS; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; SYSTEMS BIOLOGY; TRANSCRIPTION FACTORS; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 85027842034     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.07.052     Document Type: Article

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