Genetic adaptation of fatty-acid metabolism: A human-specific haplotype increasing the biosynthesis of long-chain omega-3 and omega-6 fatty acids

American Journal of Human Genetics

Volumn 90, Issue 5, 2012, Pages 809-820

  Ameur, Adam ^a   Enroth, Stefan ^a   Johansson, Åsa ^a   Zaboli, Ghazal ^a   Igl, Wilmar ^a   Johansson, Anna C V ^a   Rivas, Manuel A ^b   Daly, Mark J ^b   Schmitz, Gerd ^c   Hicks, Andrew A ^e,g   Meitinger, Thomas ^h   Feuk, Lars ^a   Van Duijn, Cornelia ^d   Oostra, Ben ^d   Pramstaller, Peter P ^e,f,g   Rudan, Igor ^i,j   Wright, Alan F ^k   Wilson, James F ^j   Campbell, Harry ^j   Gyllensten, Ulf ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e University of Lubeck   (Italy)

^f General Central Hospital   (Italy)

^g UNIVERSITY OF LÜBECK   (Germany)

^h INSTITUTE OF EPIDEMIOLOGY   (Germany)

ⁱ UNIVERSITY OF SPLIT   (Croatia)

^j UNIVERSITY OF EDINBURGH   (United Kingdom)

^k UNIVERSITY OF EDINBURGH   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE 1; FADS2 PROTEIN; LONG CHAIN FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; OXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; EVOLUTIONARY ADAPTATION; FATTY ACID SYNTHESIS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HOMO NEANDERTHALENSIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTATION, PHYSIOLOGICAL; AMINO ACID SEQUENCE; ANIMALS; CROATIA; CROSS-SECTIONAL STUDIES; DIET; EUROPEAN CONTINENTAL ANCESTRY GROUP; FATTY ACID DESATURASES; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; HAPLOTYPES; HUMANS; ITALY; LIFE STYLE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NEANDERTHALS; PHYLOGEOGRAPHY; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SCOTLAND; SEQUENCE ANALYSIS, DNA; SWEDEN;

PRIMATES;

EID: 84860737984     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2012.03.014     Document Type: Article

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