Downregulation of Paralemmin-3 Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Rats by Regulating Inflammatory Response and Inhibiting Formation of TLR4/MyD88 and TLR4/TRIF Complexes

Inflammation

Volumn 40, Issue 6, 2017, Pages 1983-1999

  Chen, Xuxin ^a   Tang, Lu ^b   Feng, Jian ^c   Wang, Yi ^d   Han, Zhihai ^a   Meng, Jiguang ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b Changsha First Hospital   (China)

^c THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIVERSITY   (China)

^d JINING MEDICAL UNIVERSITY   (China)

Author keywords

acute lung injury; acute respiratory distress syndrome; inflammation; lipopolysaccharide; paralemmin 3; toll like receptor

Indexed keywords

ADENOVIRUS VECTOR; BETA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 10; INTERLEUKIN 1BETA; MYELOID DIFFERENTIATION FACTOR 88; MYELOPEROXIDASE; PARALEMMIN 3; SHORT HAIRPIN RNA; SUPPRESSOR OF CYTOKINE SIGNALING 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; LIPOPOLYSACCHARIDE; MULTIPROTEIN COMPLEX; MYD88 PROTEIN, RAT; TICAM-1 PROTEIN, RAT; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BRONCHOALVEOLAR LAVAGE FLUID; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; ENZYME ACTIVITY; GENE SILENCING; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATION; LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY; LUNG BLOOD VESSEL; LUNG EDEMA; LUNG PARENCHYMA; MOLECULAR PATHOLOGY; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; RAT; SERUM; SURVIVAL RATE; TRANSGENE; ACUTE LUNG INJURY; ANIMAL; CHEMISTRY; DRUG EFFECT; GENETICS;

ACUTE LUNG INJURY; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CARRIER PROTEINS; DOWN-REGULATION; INFLAMMATION; LIPOPOLYSACCHARIDES; MULTIPROTEIN COMPLEXES; MYELOID DIFFERENTIATION FACTOR 88; RATS; TOLL-LIKE RECEPTOR 4;

EID: 85027326203     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-017-0639-9     Document Type: Article

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