Effects of recombinant human growth hormone on acute lung injury in endotoxemic rats

Inflammation Research

Volumn 55, Issue 11, 2006, Pages 491-497

  Yi, C ^a   Wang, S R ^b   Zhang, S Y ^b   Yu, S J ^b   Jiang, C X ^b   Zhi, M H ^b   Huang, Y ^b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Growth hormone; Intercellular adhesion molecule 1; Lung injury; Neutrophil; Nuclear factor kappa B

Indexed keywords

HUMAN GROWTH HORMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA;

ABDOMINAL INFECTION; ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRY WEIGHT; ENDOTOXEMIA; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INJURY SCALE; LEUKOCYTE COUNT; LUNG LAVAGE; LUNG WEIGHT; NEUTROPHIL COUNT; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; ENDOTOXEMIA; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMAN GROWTH HORMONE; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAPERITONEAL; INTERCELLULAR ADHESION MOLECULE-1; LUNG; NEUTROPHILS; NF-KAPPA B; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT; RNA, MESSENGER;

EID: 35548940785     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-006-6011-4     Document Type: Article

References (25)

1. Donaghy A, Ross R, Wicks C, Hughes SC, Holly J, Gimson A et al. Growth hormone therapy in patients with cirrhosis: a pilot study of efficacy and safety. Gastroenterology 1997; 113: 1617-22.
2. Prieto I, Gomez de Segura IA, Garcia Grande A, Guerra A, Pozo F, Garcia P et al. Growth hormone reduces bacterial translocation in radiation enteritis in the rat. Rev Esp Enferm Dig 1998; 90: 353-60.
3. Scopa CD, Koureleas S, Tsamandas AC, Spiliopoulou I, Alexandrides T, Filos KS et al. Beneficial effects of growth hormone and insulin-like growth factor I on intestinal bacterial translocation, endotoxemia, and apoptosis in experimentally jaundiced rats. J Am Coll Surg 2000; 190: 423-31.
4. Gelato MC.The growth hormone/insulin-like growth factor axis in critical illness. J Pediatr Endocrinol Metab 2000; 13: 1023-9.
5. Takala J, Ruokonen E, Webster NR, Nielsen MS, Zandstra DF, Vundelinckx G et al. Increased mortality associated with growth hormone treatment in critically ill adults. N Engl J Med 1999; 341: 785-92.
6. Huang Y, Wang SR, Yi C, Ying MY, Lin Y, Zhi MH. Effects of recombinant human growth hormone on rat septic shock with intraabdominal infection by E. coli. World J Gastroenterol 2002; 8: 1134-7.
7. Osman MO, Kristensen JU, Jacobsen NO, Lausten SB, Deleuran B, Deleuran M, et al. A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits. Gut 1998; 43: 232-9.
8. Cheng S, He S, Zhang J. The role of alveolar macrophage activation in rats with lung injury associated with acute necrotizing pancreatitis. Zhonghua Wai Ke Za Zhi 2002; 40: 609-12.
9. Teng Chung T, Hinds CJ. Treatment with GH and IGF-1 in critical illness. Crit Care Clin 2006; 22: 29-40.
10. Martin TR, Nakamura M, Matute-Bello G. The role of apoptosis in acute lung injury. Crit Care Medicine 2003; 31: S184-8.
11. Atabai K, Matthay MA. The pulmonary physician in critical care. 5: Acute lung injury and the acute respiratory distress syndrome: definitions and epidemiology. Thorax 2002; 57: 452-8.
12. Moraes TJ, Zurawska JH, Downey GP. Neutrophil granule contents in the pathogenesis of lung injury. Curr Opin Hematol 2006; 13: 21-7.
13. Simons RK, Junger WG, Loomis WH, Hoyt DB. Acute lung injury in endotoxemic rats is associated with sustained circulating IL-6 levels and intrapulmonary CINC activity and neutrophil recruitment - role of circulating TNF-alpha and IL-beta? Shock 1996; 6: 39-45.
14. Lee WL, Downey GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care 2001; 7: 1-7.
15. Abraham E. Neutrophils and acute lung injury. Crit Care Med 2003; 31: S195-9.
16. Shimabukuro DW, Sawa T, Gropper M. Injury and repair in lung and airways. Crit Care Med 2003; 31: S524-31.
17. [ 17] Petrache I, Birukova A, Ramirez SI, Garcia JG, Verin AD. The role of the microtubules in tumor necrosis factor-alpha-induced endothelial cell permeability. Am J Respir Cell Mol Biol 2003; 28: 574-81.
18. Shenkar R, Abraham E. Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-κB, and cyclic AMP response element binding protein. J Immunol 1999; 163: 954-62.
19. Fink, MP. Nuclear factor- [kappa] B: Is it a therapeutic target for the adjuvant treatment of sepsis? Crit Care Med 2003; 31: 2400-2.
20. Choi BT, Lee JH, Ko WS, Kim YH, Choi YH, Kang HS et al. Antiinflammatory effects of aqueous extract from Dichroa febrifuga root in rat liver. Acta Pharmacol Sin 2003; 24: 127-32.
21. Abraham E. NF- [kappa] B activation. Critical Care Medicine 2000; 28: N100-4.
22. Sun Z, Andersson R. NF-kappaB activation and inhibition: a review. Shock 2002; 18: 99-106.
23. Wright JG, Christman JW. The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am J Respir Med 2003; 2: 211-9.
24. Li Tanshi, Yin Ming, Wu Xuhui, Song Yangli, Shen Hong. Effects of growth hormone on apoptosis in the acid-induced lung injury in rats. Chinese Critical Care Medicine 2002; 14: 728-31.
25. Luo FQ, Fu HQ. Effect of growth hormone on acute lung injury. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2005; 17: 523-6.