Sulphoraphane inhibited the expressions of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 through MyD88-dependent toll-like receptor-4 pathway in cultured endothelial cells

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 22, Issue 3, 2012, Pages 215-222

  Shan, Y ^a   Lin, N ^b   Yang, X ^c   Tan, J ^a   Zhao, R ^d   Dong, S ^a   Wang, S ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Cixi Institute for Health Inspection and Supervision   (China)

^c CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^d Quzhou Center For Disease Control and Prevention   (China)

Author keywords

Adhesion molecule; Inflammation; Sulphoraphane; TLR 4

Indexed keywords

ANTIINFLAMMATORY AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; ISOTHIOCYANIC ACID DERIVATIVE; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE, E COLI O55 B5; LIPOPOLYSACCHARIDE, E COLI O55-B5; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYD88 PROTEIN, HUMAN; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; SULPHORAPHANE; TLR4 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 4; VASCULAR CELL ADHESION MOLECULE 1;

ACTIVE TRANSPORT; ARTICLE; CELL LINE; DOSE RESPONSE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENDOTHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; ISOTHIOCYANATES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTOR 4; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84857911194     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2010.06.013     Document Type: Article

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